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List of works by Hui Zhao

A highly effective TALEN-mediated approach for targeted gene disruption in Xenopus tropicalis and zebrafish

scientific article published on 17 February 2014

A sclerocornea-associated RAD21 variant induces corneal stroma disorganization

scientific article published on 05 June 2019

Accurate Profiling of Gene Expression and Alternative Polyadenylation with Whole Transcriptome Termini Site Sequencing (WTTS-Seq).

scientific article

Alternative polyadenylation coordinates embryonic development, sexual dimorphism and longitudinal growth in Xenopus tropicalis

scientific article published on 07 February 2019

Bruton's tyrosine kinase potentiates ALK signaling and serves as a potential therapeutic target of neuroblastoma

scientific article published on 16 July 2018

CFTR-β-catenin interaction regulates mouse embryonic stem cell differentiation and embryonic development

scientific article published on 11 November 2016

CRISPR/Cas9-mediated efficient and precise targeted integration of donor DNA harboring double cleavage sites in Xenopus tropicalis

scientific article published on 13 June 2018

Cardiac regeneration in Xenopus tropicalis and Xenopus laevis: discrepancies and problems.

scientific article published on 23 April 2018

Characterization of three synuclein genes in Xenopus laevis.

scientific article

Coordinated activation of the secretory pathway during notochord formation in the Xenopus embryo

scientific article (publication date: November 2009)

Developmental expression of Xenopus short-chain dehydrogenase/reductase 3

scientific article (publication date: 2010)

Developmental expression of sideroflexin family genes in Xenopus embryos.

scientific article published in October 2010

Developmental expression of three prmt genes in Xenopus ⬇️

scientific article published on 20 August 2018

Dhrs3 protein attenuates retinoic acid signaling and is required for early embryonic patterning

scientific article published on 17 September 2013

Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors.

scientific article

Early moderate exercise benefits myocardial infarction healing via improvement of inflammation and ventricular remodelling in rats

scientific article published on 15 October 2019

Efficient RNA/Cas9-mediated genome editing in Xenopus tropicalis.

scientific article published on 8 January 2014

Efficient genome editing of genes involved in neural crest development using the CRISPR/Cas9 system in Xenopus embryos

scientific article published on 31 March 2016

Efficient targeted gene disruption in Xenopus embryos using engineered transcription activator-like effector nucleases (TALENs)

scientific article (publication date: 23 October 2012)

Expression of Xenopus L-arginine:glycine amidinotransferase (XAT) during early embryonic development.

scientific article published in July 2001

Expression profile of rrbp1 genes during embryonic development and in adult tissues of Xenopus laevis.

scientific article published on 26 December 2016

Fenretinide targeting of human colon cancer sphere cells through cell cycle regulation and stress-responsive activities

article published in 2018

Forkhead box O3 protects the heart against paraquat-induced aging-associated phenotypes by upregulating the expression of antioxidant enzymes

scientific article published on 01 July 2019

FoxO3a suppresses the senescence of cardiac microvascular endothelial cells by regulating the ROS-mediated cell cycle

scientific article published on 2 February 2015

Gene delivery of hypoxia-inducible VEGF targeting collagen effectively improves cardiac function after myocardial infarction

scientific article published on 16 October 2017

Generation of gene disruptions by transcription activator-like effector nucleases (TALENs) in Xenopus tropicalis embryos.

scientific article published on 10 May 2013

Genes regulated by potassium channel tetramerization domain containing 15 (Kctd15) in the developing neural crest

scientific article (publication date: 2016)

Germline mutations of KIT in gastrointestinal stromal tumor (GIST) and mastocytosis

scientific article

Grainyhead-like 2 in development and cancer

scientific article

HPD degradation regulated by the TTC36-STK33-PELI1 signaling axis induces tyrosinemia and neurological damage

scientific article published on 19 September 2019

Heart regeneration in adult Xenopus tropicalis after apical resection

scientific article published on 13 December 2017

Heat shock 70-kDa protein 5 (Hspa5) is essential for pronephros formation by mediating retinoic acid signaling

scientific article

Heritable CRISPR/Cas9-mediated targeted integration in Xenopus tropicalis.

scientific article published on 12 August 2015

Homeoprotein hhex-induced conversion of intestinal to ventral pancreatic precursors results in the formation of giant pancreata in Xenopus embryos

scientific article (publication date: 29 May 2012)

Homology-independent multiallelic disruption via CRISPR/Cas9-based knock-in yields distinct functional outcomes in human cells

Hypoxia/ischemia promotes CXCL10 expression in cardiac microvascular endothelial cells by NFkB activation

scientific article published on 15 February 2016

IL-1β inhibits β-Klotho expression and FGF19 signaling in hepatocytes

scientific article published on 15 December 2015

Inheritable and precise large genomic deletions of non-coding RNA genes in zebrafish using TALENs

scientific article

Knock-in of large reporter genes in human cells via CRISPR/Cas9-induced homology-dependent and independent DNA repair

scientific article published on 4 February 2016

Localization of an axon growth inhibitory molecule Nogo and its receptor in the spinal cord of mouse embryos.

scientific article published on 13 October 2009

Localization of protein kinase C isoforms in the optic pathway of mouse embryos and their role in axon routing at the optic chiasm.

scientific article published on 23 May 2014

Lrig3 regulates neural crest formation in Xenopus by modulating Fgf and Wnt signaling pathways

scientific article (publication date: April 2008)

Mutagenesis at specific genomic loci of amphioxus Branchiostoma belcheri using TALEN method.

scientific article

Mutagenesis in Xenopus and Zebrafish using TALENs

scientific article published in January 2016

Mutation screening of HOXA7 and HOXA9 genes in Chinese women with Müllerian duct abnormalities

scientific article published on 12 August 2014

Myoskeletin, a factor related to Myocardin, is expressed in somites and required for hypaxial muscle formation in Xenopus

scientific article (publication date: 2007)

Nogo-B is the major form of Nogo at the floor plate and likely mediates crossing of commissural axons in the mouse spinal cord

scientific article

PPARγ maintains the metabolic heterogeneity and homeostasis of renal tubules

scientific article published on 09 November 2018

PSORI-CM02 Formula Increases CD4+ Foxp3+ Regulatory T Cell Frequency and Ameliorates Imiquimod-Induced Psoriasis in Mice.

scientific article published in January 2017

Quercetin ameliorates imiquimod-induced psoriasis-like skin inflammation in mice via the NF-κB pathway.

scientific article published on 9 May 2017

Retinoic acid promotes stem cell differentiation and embryonic development by transcriptionally activating CFTR.

scientific article published on 8 January 2018

Retinoic acid synthesis and functions in early embryonic development

scientific article

Six2 Is a Coordinator of LiCl-Induced Cell Proliferation and Apoptosis

scientific article published on 08 September 2016

Src-like adaptor protein 2 (SLAP2) binds to and inhibits FLT3 signaling

scientific article published on 21 July 2016

The CXCL10/CXCR3 axis promotes cardiac microvascular endothelial cell migration via the p38/FAK pathway in a proliferation-independent manner

scientific article published on 30 January 2016

The Proto-oncogene Transcription Factor Ets1 Regulates Neural Crest Development through Histone Deacetylase 1 to Mediate Output of Bone Morphogenetic Protein Signaling.

scientific article

The TrkB-T1 receptor mediates BDNF-induced migration of aged cardiac microvascular endothelial cells by recruiting Willin

scientific article published on 22 January 2019

The spatiotemporal relationships between chondroitin sulfate proteoglycans and terminations of calcitonin gene related peptide and parvalbumin immunoreactive afferents in the spinal cord of mouse embryos

scientific article published on 5 July 2017

Toxic effects of polybrominated diphenyl ethers (BDE 47 and 99) and localization of BDE-99-induced cyp1a mRNA in zebrafish larvae.

scientific article published on 14 November 2017

Tuning the Protein Phosphorylation by Receptor Type Protein Tyrosine Phosphatase Epsilon (PTPRE) in Normal and Cancer Cells

Tyrosine 842 in the activation loop is required for full transformation by the oncogenic mutant FLT3-ITD.

scientific article published on 7 March 2017

WGEF activates Rho in the Wnt-PCP pathway and controls convergent extension in Xenopus gastrulation

scientific article

Wnt16 attenuates osteoarthritis progression through a PCP/JNK-mTORC1-PTHrP cascade

scientific article published on 11 February 2019

XBP1 forms a regulatory loop with BMP-4 and suppresses mesodermal and neural differentiation in Xenopus embryos.

scientific article published on 8 November 2005

XETOR regulates the size of the proneural domain during primary neurogenesis in Xenopus laevis.

scientific article published in November 2002

Xenopus X-box binding protein 1, a leucine zipper transcription factor, is involved in the BMP signaling pathway.

scientific article published in May 2003

miR181c promotes apoptosis and suppresses proliferation of metanephric mesenchyme cells by targeting Six2 in vitro.

scientific article published on 3 September 2014

microRNA-221 Enhances MYCN via Targeting Nemo-like Kinase and Functions as an Oncogene Related to Poor Prognosis in Neuroblastoma.

scientific article published on 21 December 2016

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