List of works by Lode Wyns

1H NMR study of the interaction ofN,N′,N″‐triacetyl chitotriose with Ac‐AMP2, a sugar binding antimicrobial protein isolated fromAmaranthus caudatus ⬇️

scientific article published on August 21, 1995

1H, 13C and 15N assignments of a camelid nanobody directed against human α-synuclein

article

1H, 13C and 15N backbone resonance assignment of the arsenate reductase from Staphylococcus aureus in its reduced state

scientific article published on 01 May 2001

A Nanobody Binding to Non-Amyloidogenic Regions of the Protein Human Lysozyme Enhances Partial Unfolding but Inhibits Amyloid Fibril Formation

scientific article

A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme

scientific article

A catalytic function for the structurally conserved residue Phe 100 of ribonuclease T1.

scientific article

A comparative structural study on the steroids [1,2,5]oxadiazolo[3', 4':3,4]-5 alpha-pregn-16-en-20-one oxime (HS998), [1,2,5]oxadiazolo[3, 4':3,4]-5 beta-pregn-16-en-20-one (HS973) by NMR, molecular modeling, and X-ray investigations

scientific article published on 01 October 1995

A model for histone H5-DNA interaction: Simultaneous minor and major groove binding ⬇️

scientific article published on January 31, 1991

A single-domain antibody fragment in complex with RNase A: non-canonical loop structures and nanomolar affinity using two CDR loops

scientific article

A structure of the complex between concanavalin A and methyl-3,6-di-O-(alpha-D-mannopyranosyl)-alpha-D-mannopyranoside reveals two binding modes

scientific article

Align-m--a new algorithm for multiple alignment of highly divergent sequences

scientific article published on 12 February 2004

All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade

scientific article

Allostery and intrinsic disorder mediate transcription regulation by conditional cooperativity

scientific article

An evolutionaty scheme for the histones as derived from a study of internal repetitions and homologies among the different classes

scientific article published on March 21, 1977

An unusual carbohydrate binding site revealed by the structures of two Maackia amurensis lectins complexed with sialic acid-containing oligosaccharides

scientific article

Antigen Binding and Solubility Effects upon the Veneering of a Camel VHH in Framework-2 to Mimic a VH

scientific article published on 01 July 2005

Antigen specificity and high affinity binding provided by one single loop of a camel single-domain antibody

scientific article

Arsenate reductase from S. aureus plasmid pI258 is a phosphatase drafted for redox duty

scientific article

Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchange

scientific article

Assembly of oligonucleosomes into a limit series of multimeric higher-order chromatin structures

scientific article published in 1985

Atomic structure of a nanobody-trapped domain-swapped dimer of an amyloidogenic  2-microglobulin variant

scientific article

Beta-lactamase inhibitors derived from single-domain antibody fragments elicited in the camelidae

scientific article

Camel heavy-chain antibodies: diverse germline V(H)H and specific mechanisms enlarge the antigen-binding repertoire

scientific article published on March 2000

Camel single-domain antibodies as modular building units in bispecific and bivalent antibody constructs

scientific article published on 25 October 2000

Camel single-domain antibody inhibits enzyme by mimicking carbohydrate substrate

scientific article

Camelid immunoglobulins and nanobody technology.

scientific article published on 17 October 2008

Canonical antigen-binding loop structures in immunoglobulins: more structures, more canonical classes?

scientific article

Carbohydrate binding, quaternary structure and a novel hydrophobic binding site in two legume lectin oligomers from Dolichos biflorus

scientific article

Chemical basis for the affinity maturation of a camel single domain antibody

scientific article published on 21 September 2004

Chloroplasts assemble the major subunit FaeG of Escherichia coli F4 (K88) fimbriae to strand-swapped dimers

scientific article published on 4 May 2007

Combining site-specific mutagenesis and seeding as a strategy to crystallize 'difficult' proteins: the case of Staphylococcus aureus thioredoxin.

scientific article published on 30 November 2006

Combining sites of bacterial fimbriae

scientific article published on 23 August 2007

Comparative filter binding study of H5 to nucleosome core particles, H1, H5 depleted chromatosomes and DNA fragments

scientific article published on 01 January 1988

Comparison of llama VH sequences from conventional and heavy chain antibodies

scientific article published on 01 November 1997

Complex of ribonuclease Sa with a cyclic nucleotide and a proposed model for the reaction intermediate

scientific article

Concanavalin A crystallized in complex with the trisaccharide 3,6-di-O-methyl-(alpha-D-mannopyranosyl)-alpha-D-mannopyranoside

scientific article published on 01 July 1996

Conserved waters in legume lectin crystal structures. The importance of bound water for the sequence-structure relationship within the legume lectin family

scientific article published on 01 October 1994

Consistency matrices: quantified structure alignments for sets of related proteins.

scientific article

Correction: Intervening with Urinary Tract Infections Using Anti-Adhesives Based on the Crystal Structure of the FimH–Oligomannose-3 Complex

scientific article

Coupling of domain swapping to kinetic stability in a thioredoxin mutant

scientific article

Cross-linking of nucleosomal histones with monofunctional imidoesters ⬇️

scientific article published on July 1, 1978

Crystal structure determination and refinement at 2.3-.ANG. resolution of the lentil lectin. [Erratum to document cited in CA119(17):176148u]

scientific article published on 01 December 1993

Crystal structure determination and refinement at 2.3-A resolution of the lentil lectin

scientific article

Crystal structure of CcdB, a topoisomerase poison from E. coli

scientific article

Crystal structure of Pterocarpus angolensis lectin in complex with glucose, sucrose, and turanose

scientific article (publication date: 2 May 2003)

Crystal structure of RNase T1 with 3'-guanylic acid and guanosine

scientific article

Crystal structure of a camel single-domain VH antibody fragment in complex with lysozyme

scientific article

Crystal structure of arcelin-5, a lectin-like defense protein from Phaseolus vulgaris

scientific article

Crystal structure of the intrinsically flexible addiction antidote MazE

scientific article (publication date: 25 July 2003)

Crystallization and crystal manipulation of a steric chaperone in complex with its lipase substrate.

scientific article published on 30 July 2005

Crystallization and crystal manipulation of the Pterocarpus angolensis seed lectin.

scientific article published on 26 May 2005

Crystallization and preliminary X-ray analysis of a protease inhibitor from the latex of Carica papaya.

scientific article published on 30 November 2006

Crystallization and preliminary X-ray analysis of the Man(alpha1-2)Man-specific lectin from Bowringia mildbraedii in complex with its carbohydrate ligand

scientific article

Crystallization of CcdB in complex with a GyrA fragment

scientific article published on 21 May 2004

Crystallization of Doc and the Phd-Doc toxin-antitoxin complex

scientific article published on 28 October 2008

Crystallization of ccdB

scientific article published on 01 September 1998

Crystallization of glycosylated and nonglycosylated phytohemagglutinin-L

scientific article published on 01 January 1996

Crystallization of ornithine acetyltransferase from yeast by counter-diffusion and preliminary X-ray study

scientific article published on 30 November 2006

Crystallization of the C-terminal domain of the addiction antidote CcdA in complex with its toxin CcdB

scientific article published on 30 September 2005

Crystallization of the FaeE chaperone of Escherichia coli F4 fimbriae

scientific article published on April 2005

Crystallization of two related lectins from the legume plant Dolichos biflorus

scientific article published on November 1998

Crystallographic Study of Glu58Ala RNase T1.cntdot.2'-Guanosine Monophosphate at 1.9-.ANG. Resolution

scientific article published in 1994

Crystallographic structure of metal-free concanavalin A at 2.5 A resolution

scientific article

Crystallographic study of Glu58Ala RNase T1 x 2'-guanosine monophosphate at 1.9-A resolution

scientific article

Degenerate interfaces in antigen-antibody complexes

scientific article

Development of a downstream process for the isolation of Staphylococcus aureus arsenate reductase overproduced in Escherichia coli.

scientific article

Differences in rearrangements of H1 and H5 in chicken erythrocyte chromatin

scientific article published on 01 March 1981

Differential association of linker histones H1 and H5 with telomeric nucleosomes in chicken erythrocytes

scientific article published on December 1994

Dissection of the ribonuclease T1 subsite. The transesterification kinetics of Asn36Ala and Asn98Ala ribonuclease T1 for minimal dinucleoside phosphates

scientific article published on 01 February 1992

Doc of Prophage P1 Is Inhibited by Its Antitoxin Partner Phd through Fold Complementation

scientific article

E.coli RNase 1 in complex with d(CGCGATCGCG)

scientific article published on 24 June 2008

Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies. African trypanosomes as paradigm

scientific article

Encapsulation of therapeutic nucleoside hydrolase in functionalised nanocapsules

Engineering a camelid antibody fragment that binds to the active site of human lysozyme and inhibits its conversion into amyloid fibrils

scientific article published on 25 September 2008

Expression in E. coli and purification of the active autoprotease P20 of classical swine fever virus

scientific article published on January 1996

FaeG from F4ac ETEC strain 5_95, produced in tobacco plant chloroplast

scientific article published on 10 April 2007

FaeG from F4ac ETEC strain GIS26, produced in tobacco plant chloroplast

scientific article published on 10 April 2007

Formation, stability and core histone positioning of nucleosomes reassembled on bent and other nucleosome-derived DNA.

scientific article

Functional Interactions among the His40, Glu58 and His92 Catalysts of Ribonuclease T1 as Studied by Double and Triple Mutants

H NMR study of the solution structure of Ac-AMP2, a sugar binding antimicrobial protein isolated from Amaranthus caudatus

scientific article

Heterologous expression, purification and characterisation of the extracellular domain of trypanosome invariant surface glycoprotein ISG75.

scientific article published in May 2008

Histidine-40 of ribonuclease T1 acts as base catalyst when the true catalytic base, glutamic acid-58, is replaced by alanine

scientific article published in September 1990

Histone H1 can be removed selectively from chicken erythrocyte chromatin at near physiological conditions

scientific article

Homo- and heteronuclear two-dimensional NMR studies of the globular domain of histone H1: Sequential assignment and secondary structure

scientific article (publication date: October 1993)

Homo- and heteronuclear two-dimensional NMR studies of the globular domain of histone H1: full assignment, tertiary structure, and comparison with the globular domain of histone H5

scientific article

How a Plant Lectin Recognizes High Mannose Oligosaccharides

scientific article

How thioredoxin can reduce a buried disulphide bond

scientific article

How thioredoxin dissociates its mixed disulfide

scientific article

Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography

scientific article

Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies.

scientific article

Impact of natural variation in bacterial F17G adhesins on crystallization behaviour.

scientific article

Influence of histones H1/H5 on the DNA coiling in the nucleosome — electric dichroism and birefringence study

scientific article published in 1981

Interplay between ion binding and catalysis in the thioredoxin-coupled arsenate reductase family

scientific article published on 06 June 2006

Interplay between metal binding and cis/trans isomerization in legume lectins: structural and thermodynamic study of P. angolensis lectin

scientific article published on 21 June 2006

Intervening with urinary tract infections using anti-adhesives based on the crystal structure of the FimH-oligomannose-3 complex

scientific article

Intricate interactions within the ccd plasmid addiction system

scientific article published on 07 December 2001

Investigation of the functional interplay between the primary site and the subsite of RNase T1: Kinetic analysis of single and multiple mutants for modified substrates

scholarly article by Jan Steyaert published in April 1994

Isolectins I-A and I-B of Griffonia (Bandeiraea) simplicifolia. Crystal structure of metal-free GS I-B(4) and molecular basis for metal binding and monosaccharide specificity

scientific article

Kinetics and active site dynamics of Staphylococcus aureus arsenate reductase

scientific article published on 24 July 2001

Legume lectin structure.

scientific article

Limitations of the poly(glutamic acid) reconstitution method in the reassembly of mono- and dinucleosomes

scientific article published in September 1986

Location of the three disulfide bonds in an antimicrobial peptide from Amaranthus caudatus using mass spectrometry

scientific article published on 01 April 1997

Loss of splice consensus signal is responsible for the removal of the entire C(H)1 domain of the functional camel IGG2A heavy-chain antibodies

scientific article

Lys13 plays a crucial role in the functional adaptation of the thermophilic triose-phosphate isomerase from Bacillus stearothermophilus to high temperatures

scientific article published on 2 July 1999

Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies

scholarly article

Molecular basis of gyrase poisoning by the addiction toxin CcdB.

scientific article published on 7 April 2005

Multiple alignment of sequences and structures

scientific article published in January 2002

N-terminal truncation enables crystallization of the receptor-binding domain of the FedF bacterial adhesin

scientific article published on 30 November 2006

NMR, molecular modeling, and crystallographic studies of lentil lectin-sucrose interaction

scientific article

Nanobodies Raised against Monomeric α-Synuclein Distinguish between Fibrils at Different Maturation Stages

scientific article published on 01 April 2013

Neutron scattering of chromatin multinucleosomes

article

Nonspecific base recognition mediated by water bridges and hydrophobic stacking in ribonuclease I fromEscherichia coli

scientific article published in April 2008

Novel structures of plant lectins and their complexes with carbohydrates.

scientific article

Overexpression, purification and crystallization of bacteriocin LlpA from Pseudomonas sp. BW11M1.

scientific article published on 23 September 2004

Pancreatic ribonuclease co-crystallizes with the dinucleotide dCpdG in two distinct forms

scientific article published on 01 August 1992

Potent enzyme inhibitors derived from dromedary heavy-chain antibodies

scientific article published on July 1998

Preparation and behaviour of H1-depleted, H5-containing chicken erythrocyte chromatin [proceedings]

scientific article published on 01 February 1980

Preparation and purification of mononucleosome particles containing histone H5

scientific article published on 01 September 1980

Protection of discrete DNA fragments by the complex H1-octamerhistones or H5-octamerhistones after micrococcal nuclease digestion

scientific article

Protein crystallization in hydrogel beads.

scientific article published on 16 August 2005

Purification and crystallization of Vibrio fischeri CcdB and its complexes with fragments of gyrase and CcdA.

scientific article published on 30 March 2007

Purification of an oxidation-sensitive enzyme, pI258 arsenate reductase from Staphylococcus aureus

scientific article published on 01 June 2003

Purification, circular dichroism analysis, crystallization and preliminary X-ray diffraction analysis of the F plasmid CcdB killer protein.

scientific article

Purification, crystallization, and preliminary X-ray studies on the rhizome lectin from stinging nettle and its complex with NN'N"-triacetylchitotriose

scientific article

Quantitative analysis of the contribution of Glu46 and Asn98 to the guanosine specificity of ribonuclease T1.

scientific article

Quaternary structure of UEA-II, the chitobiose specific lectin from gorse

scientific article published on 01 September 1998

Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin

scientific article published on 01 January 2005

Recognition of the intrinsically flexible addiction antidote MazE by a dromedary single domain antibody fragment. Structure, thermodynamics of binding, stability, and influence on interactions with DNA.

scientific article published on 17 January 2003

Reconsidering the energetics of ribonuclease catalysed RNA hydrolysis

scientific article published on 01 October 1998

Reduced global cooperativity is a common feature underlying the amyloidogenicity of pathogenic lysozyme mutations

Rejuvenation of CcdB-poisoned gyrase by an intrinsically disordered protein domain

scientific article

Role of histidine-40 in ribonuclease T1 catalysis: three-dimensionalstructures of the partially active His40Lys mutant

scientific article

SABmark--a benchmark for sequence alignment that covers the entire known fold space

scientific article published on 27 August 2004

Scatter analysis of discrete-sized chromatin fragments favours a cylindrical organization

scientific article published in September 1985

Selection and identification of single domain antibody fragments from camel heavy-chain antibodies

scientific article (publication date: 15 September 1997)

Sequence-specific 1H, 15N and 13C resonance assignments of the 23.7-kDa homodimeric toxin CcdB from Vibrio fischeri

scientific article published on 3 April 2009

Sequential structural changes upon zinc and calcium binding to metal-free concanavalin A

scientific article

Single-domain antibody fragments with high conformational stability

scientific article published on March 2002

Solving the phase problem for carbohydrate-binding proteins using selenium derivatives of their ligands: a case study involving the bacterial F17-G adhesin.

scientific article published on 23 May 2003

Specific potassium binding stabilizes pI258 arsenate reductase from Staphylococcus aureus

scientific article published on 07 April 2003

Strongin VivoMaturation Compensates for Structurally Restricted H3 Loops in Antibody Repertoires

scientific article published in Journal of Biological Chemistry

Structural analysis of two crystal forms of lentil lectin at 1.8 A resolution

scientific article

Structural and thermodynamic characterization of pre- and postpolymerization states in the F4 fimbrial subunit FaeG

scientific article

Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lectin.

scientific article published on June 2006

Structural basis of carbohydrate recognition by a Man(alpha1-2)Man-specific lectin from Bowringia milbraedii.

scientific article published on 27 March 2006

Structural basis of carbohydrate recognition by lectin II from Ulex europaeus, a protein with a promiscuous carbohydrate-binding site

scientific article

Structural basis of carbohydrate recognition by the lectin LecB from Pseudomonas aeruginosa

scientific article

Structural basis of oligomannose recognition by the Pterocarpus angolensis seed lectin

scientific article

Structure and properties of a complex of α-synuclein and a single-domain camelid antibody

scientific article

Structure of a membrane-based steric chaperone in complex with its lipase substrate

scientific article published on 05 March 2006

Structure of chymopapain at 1.7 A resolution

scientific article

Structure of the crystalline complex of cytidylic acid (2'-CMP) with ribonuclease at 1.6 A resolution. Conservation of solvent sites in RNase-A high-resolution structures

scientific article published in November 1993

Structure of the crystalline complex of deoxycytidylyl-3',5'-guanosine (3',5'-dCpdG) cocrystallized with ribonuclease at 1.9 A resolution

scientific article published on 01 September 1995

Studies on chromatin topology with photoactivatable cross-linkers [proceedings].

scientific article

Study of the structural and dynamic effects in the FimH adhesin upon α-d-heptyl mannose binding

scientific article

Subsite interactions of ribonuclease T1: Asn36 and Asn98 accelerate GpN transesterification through interactions with the leaving nucleoside N.

scientific article published in September 1991

Subsite interactions of ribonuclease T1: viscosity effects indicate that the rate-limiting step of GpN transesterification depends on the nature of N.

scientific article published in September 1991

The F plasmid CcdB protein induces efficient ATP-dependent DNA cleavage by gyrase.

scientific article

The F4 fimbrial chaperone FaeE is stable as a monomer that does not require self-capping of its pilin-interactive surfaces

scientific article published in May 2009

The activation of electrophile, nucleophile and leaving group during the reaction catalysed by pI258 arsenate reductase

scientific article published on 01 June 2006

The affinity of the FimH fimbrial adhesin is receptor-driven and quasi-independent of Escherichia coli pathotypes

scientific article

The conserved active site proline determines the reducing power of Staphylococcus aureus thioredoxin

scientific article

The crystal structure of recombinant rat pancreatic RNase A

scientific article

The crystal structure of triosephosphate isomerase (TIM) from Thermotoga maritima: a comparative thermostability structural analysis of ten different TIM structures

scientific article

The crystal structures of Man(alpha1-3)Man(alpha1-O)Me and Man(alpha1-6)Man(alpha1-O)Me in complex with concanavalin A

scientific article

The crystallographic structure of phytohemagglutinin-L

scientific article

The essential catalytic redox couple in arsenate reductase from Staphylococcus aureus.

scientific article

The fimbrial adhesin F17-G of enterotoxigenic Escherichia coli has an immunoglobulin-like lectin domain that binds N-acetylglucosamine

scientific article

The interaction of histone H5 and its globular domain with core particles, depleted chromatosomes, polynucleosomes, and a DNA decamer

scientific article

The monosaccharide binding site of lentil lectin: an X-ray and molecular modelling study

scientific article

The oxidase DsbA folds a protein with a nonconsecutive disulfide

scientific article

The role of weak protein-protein interactions in multivalent lectin-carbohydrate binding: crystal structure of cross-linked FRIL

scientific article

The structural features of concanavalin A governing non-proline peptide isomerization

scientific article

The structural organization of dinudeosomes and oligonucleosomes. Electric dichroism and birefringence study ⬇️

scientific article published on November 11, 1981

The structure of a triple mutant of pI258 arsenate reductase from Staphylococcus aureus and its 5-thio-2-nitrobenzoic acid adduct.

scientific article

The structures of RNase A complexed with 3'-CMP and d(CpA): active site conformation and conserved water molecules

scientific article published on December 1994

The thermodynamic stability of the proteins of the ccd plasmid addiction system

scientific article published on June 2000

Thermodynamics and kinetics of unfolding of the thermostable trimeric adenylate kinase from the archaeon Sulfolobus acidocaldarius.

scientific article

Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology

scientific article

Toxin-antitoxin modules as bacterial metabolic stress managers

scientific article

Trimeric domain-swapped barnase

scientific article

Triose-phosphate isomerase (TIM) of the psychrophilic bacterium Vibrio marinus. Kinetic and structural properties

scientific article

Two crystal forms of the lentil lectin diffract to high resolution

scientific article published on 01 January 1992

Untangle, a tool for filtering overlapping diffraction patterns from multicrystals

scientific article

Upon the observation of superbeads in chromatin.

scientific article

Validation of Reactivity Descriptors to Assess the Aromatic Stacking within the Tyrosine Gate of FimH

scientific article

Weak protein-protein interactions in lectins: the crystal structure of a vegetative lectin from the legume Dolichos biflorus

scientific article

Zinc/calcium- and cadmium/cadmium-substituted concanavalin A: interplay of metal binding, pH and molecular packing

scientific article

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