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List of works by Fabio A Zucca

A lysosome-plasma membrane-sphingolipid axis linking lysosomal storage to cell growth arrest

scientific article published on 10 May 2018

Amyloid beta and neuromelanin--toxic or protective molecules? The cellular context makes the difference.

scientific article

Biosynthetic pathway to neuromelanin and its aging process

scientific article published on 01 October 2012

Contrast mechanisms associated with neuromelanin-MRI.

scientific article published on 26 December 2016

Dopamine, Oxidative Stress and Protein-Quinone Modifications in Parkinson's and Other Neurodegenerative Diseases

scientific article published on 21 March 2019

Elemental mapping of Neuromelanin organelles of human Substantia Nigra: correlative ultrastructural and chemical analysis by analytical transmission electron microscopy and nano-secondary ion mass spectrometry

scientific article

Engineered nanoparticles. How brain friendly is this new guest?

scientific article

Highly Effective Protocol for Differentiation of Induced Pluripotent Stem Cells (iPS) into Melanin-Producing Cells

scientific article published in 2021

Interaction of Neuromelanin with Xenobiotics and Consequences for Neurodegeneration; Promising Experimental Models

Interactions of dopamine, iron, and alpha-synuclein linked to dopaminergic neuron vulnerability in Parkinson's disease and Neurodegeneration with Brain Iron Accumulation disorders

Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease

scientific article

Iron, Myelin, and the Brain: Neuroimaging Meets Neurobiology

scientific article published on 29 April 2019

Locus coeruleus imaging as a biomarker for noradrenergic dysfunction in neurodegenerative diseases

scientific article published on 01 September 2019

MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration

scientific article

Melanins and melanogenesis: from pigment cells to human health and technological applications

scientific article

Neuromelanin can protect against iron-mediated oxidative damage in system modeling iron overload of brain aging and Parkinson's disease

scientific article published on 4 July 2008

Neuromelanin detection by magnetic resonance imaging (MRI) and its promise as a biomarker for Parkinson's disease

scientific article published on 10 April 2018

Neuromelanin of the human substantia nigra: an update

scientific article published on 24 October 2013

Neuromelanin of the substantia nigra: a neuronal black hole with protective and toxic characteristics

scientific article published on November 1, 2003

Neuromelanin organelles are specialized autolysosomes that accumulate undegraded proteins and lipids in aging human brain and are likely involved in Parkinson's disease.

scientific article

Neuromelanin-sensitive MRI as a noninvasive proxy measure of dopamine function in the human brain

scientific article published on 22 February 2019

Neuromelanins in brain aging and Parkinson's disease: synthesis, structure, neuroinflammatory, and neurodegenerative role

Neuromelanins isolated from different regions of the human brain exhibit a common surface photoionization threshold

scientific article published on 19 November 2008

Neuromelanins of human brain have soluble and insoluble components with dolichols attached to the melanic structure

scientific article

Neuronal pigmented autophagic vacuoles: lipofuscin, neuromelanin, and ceroid as macroautophagic responses during aging and disease

scientific article published on April 2008

New melanic pigments in the human brain that accumulate in aging and block environmental toxic metals

scholarly article

Norepinephrine and its metabolites are involved in the synthesis of neuromelanin derived from the locus coeruleus

scientific article

Protective and toxic roles of dopamine in Parkinson's disease

scientific article published on 18 March 2014

Reduction of the nitro group to amine by hydroiodic acid to synthesize o-aminophenol derivatives as putative degradative markers of neuromelanin.

scientific article published on 16 June 2014

Synthesis, Structure Characterization, and Evaluation in Microglia Cultures of Neuromelanin Analogues Suitable for Modeling Parkinson's Disease.

scientific article published on 28 November 2016

The neuromelanin of human substantia nigra: physiological and pathogenic aspects

scientific article

The role of iron in brain ageing and neurodegenerative disorders.

scientific article

The role of tyrosine hydroxylase as a key player in neuromelanin synthesis and the association of neuromelanin with Parkinson's disease

The structure of neuromelanin as studied by chemical degradative methods

scientific article published in August 2003

The surface oxidation potential of human neuromelanin reveals a spherical architecture with a pheomelanin core and a eumelanin surface

scientific article published on 25 September 2006

Water‐Soluble Melanin–Protein–Fe/Cu Conjugates Derived from Norepinephrine as Reliable Models for Neuromelanin of Human Brain Locus Coeruleus