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List of works by Masayuki Shimada

A Proinflammatory Response of Bovine Endometrial Epithelial Cells to Active Sperm In Vitro.

scientific article published on 16 January 2018

A simple sperm-sexing method that activates TLR7/8 on X sperm for the efficient production of sexed mouse or cattle embryos

scientific article published on 17 July 2020

Activation of PKA, p38 MAPK and ERK1/2 by gonadotropins in cumulus cells is critical for induction of EGF-like factor and TACE/ADAM17 gene expression during in vitro maturation of porcine COCs

scientific article

Activation of Toll-like receptor 7/8 encoded by the X chromosome alters sperm motility and provides a novel simple technology for sexing sperm

scientific article published on 13 August 2019

Adiponectin and its receptors modulate granulosa cell and cumulus cell functions, fertility, and early embryo development in the mouse and human.

scientific article

Adverse effect of superoxide-induced mitochondrial damage in granulosa cells on follicular development in mouse ovaries

scientific article published on 29 December 2020

Androgen/androgen receptor pathway regulates expression of the genes for cyclooxygenase-2 and amphiregulin in periovulatory granulosa cells

scientific article published on 13 February 2013

Anti-bacterial factors secreted from cumulus cells of ovulated COCs enhance sperm capacitation during in vitro fertilization

scientific article published on 4 October 2012

Artificial Insemination With Seminal Plasma Improves the Reproductive Performance of Frozen-Thawed Boar Epididymal Spermatozoa

article

Assessment of human oocyte developmental competence by cumulus cell morphology and circulating hormone profile

scientific article published in January 2007

Bovine embryo induces an anti-inflammatory response in uterine epithelial cells and immune cells in vitro: possible involvement of interferon tau as an intermediator.

scientific article published on 10 June 2017

Contribution of high p34cdc2 kinase activity to premature chromosome condensation of injected somatic cell nuclei in rat oocytes

scientific journal article

Creatine enhances the duration of sperm capacitation: a novel factor for improving in vitro fertilization with small numbers of sperm

scientific article published on 9 April 2018

Cutting the ovarian surface improves the responsiveness to exogenous hormonal treatment in aged mice

scientific article published on 26 August 2020

De Novo-Synthesized Retinoic Acid in Ovarian Antral Follicles Enhances FSH-Mediated Ovarian Follicular Cell Differentiation and Female Fertility

scientific article published on 29 March 2016

Delay of nuclear maturation and reduction in developmental competence of pig oocytes after mineral oil overlay of in vitro maturation media.

scientific article published in October 2002

Down-regulated expression of A disintegrin and metalloproteinase with thrombospondin-like repeats-1 by progesterone receptor antagonist is associated with impaired expansion of porcine cumulus-oocyte complexes.

scientific article

EGF-like factors induce expansion of the cumulus cell-oocyte complexes by activating calpain-mediated cell movement.

scientific article

Effects of wortmannin on the kinetics of GVBD and the activities of the maturation-promoting factor and mitogen-activated protein kinase during bovine oocyte maturation in vitro.

scientific article published in June 2000

Endogenous acetaldehyde toxicity during antral follicular development in the mouse ovary

scientific article published on 18 January 2012

Evidence that interferon-tau secreted from Day-7 embryo in vivo generates anti-inflammatory immune response in the bovine uterus

scientific article published on 30 April 2018

FSH and LH induce progesterone production and progesterone receptor synthesis in cumulus cells: a requirement for meiotic resumption in porcine oocytes.

scientific article published in July 2002

Fecal Progestagen and Estrone During Pregnancy in a Giraffe: A Case Report

scientific article published on 29 September 2006

Gene Expression and Protein Synthesis in Mitochondria Enhance the Duration of High-Speed Linear Motility in Boar Sperm

article

Gene expression profiles of cumulus cell oocyte complexes during ovulation reveal cumulus cells express neuronal and immune-related genes: does this expand their role in the ovulation process?

scientific article published on 2 February 2006

Hormone-induced expression of tumor necrosis factor alpha-converting enzyme/A disintegrin and metalloprotease-17 impacts porcine cumulus cell oocyte complex expansion and meiotic maturation via ligand activation of the epidermal growth factor recept

scientific article published on 27 September 2007

Immune-like mechanisms in ovulation

scientific article published on 11 April 2008

Induced expression of pattern recognition receptors in cumulus oocyte complexes: novel evidence for innate immune-like functions during ovulation

scientific article published on 24 August 2006

Induction of immune-related gene expression by seminal exosomes in the porcine endometrium

scientific article published on 16 November 2017

Inductions of granulosa cell luteinization and cumulus expansion are dependent on the fibronectin-integrin pathway during ovulation process in mice

scientific article published on 8 February 2018

Inhibition of phosphatidylinositol 3-kinase or mitogen-activated protein kinase kinase leads to suppression of p34(cdc2) kinase activity and meiotic progression beyond the meiosis I stage in porcine oocytes surrounded with cumulus cells.

scientific article published in August 2001

Interleukin-6: an autocrine regulator of the mouse cumulus cell-oocyte complex expansion process

scientific article published on 19 March 2009

Involvement of Ca2+-dependent proteasome in the degradation of both cyclin B1 and Mos during spontaneous activation of matured rat oocytes.

scientific article published on 5 October 2006

LH reduces proliferative activity of cumulus cells and accelerates GVBD of porcine oocytes.

scientific article published in November 2003

LH-induced neuregulin 1 (NRG1) type III transcripts control granulosa cell differentiation and oocyte maturation.

scientific article

Luteinizing hormone receptor formation in cumulus cells surrounding porcine oocytes and its role during meiotic maturation of porcine oocytes.

scientific article published on 13 November 2002

MAPK3/1 (ERK1/2) in ovarian granulosa cells are essential for female fertility.

scientific article

Methyl-beta cyclodextrin and creatine work synergistically under hypoxic conditions to improve the fertilization ability of boar ejaculated sperm

scientific article published on 01 January 2020

Mice null for Frizzled4 (Fzd4-/-) are infertile and exhibit impaired corpora lutea formation and function

scientific journal article

Mitochondrial Protein Turnover Is Critical for Granulosa Cell Proliferation and Differentiation in Antral Follicles

scientific article published on 10 December 2018

Mitogen-activated protein kinase kinase inhibitor suppresses cyclin B1 synthesis and reactivation of p34cdc2 kinase, which improves pronuclear formation rate in matured porcine oocytes activated by Ca2+ ionophore

scientific article published on 19 November 2003

Motility and penetration competence of frozen-thawed miniature pig spermatozoa are substantially altered by exposure to seminal plasma before freezing.

scientific article

Neuregulin 1 Regulates Proliferation of Leydig Cells to Support Spermatogenesis and Sexual Behavior in Adult Mice

scientific article published on 12 October 2016

New strategies of boar sperm cryopreservation: development of novel freezing and thawing methods with a focus on the roles of seminal plasma.

scientific article published on 03 July 2012

Oviduct epithelium induces interferon-tau in bovine Day-4 embryos, which generates an anti-inflammatory response in immune cells.

scientific article published on 18 May 2018

Paracrine and autocrine regulation of epidermal growth factor-like factors in cumulus oocyte complexes and granulosa cells: key roles for prostaglandin synthase 2 and progesterone receptor

scientific article published on 16 March 2006

Phosphatidylinositol 3-kinase in cumulus cells is responsible for both suppression of spontaneous maturation and induction of gonadotropin-stimulated maturation of porcine oocytes

scientific article published on October 1, 2003

Polymyxin B neutralizes bacteria-released endotoxin and improves the quality of boar sperm during liquid storage and cryopreservation

article by Tetsuji Okazaki et al published December 2010 in Theriogenology

Positive Feedback Loop Between Prostaglandin E2 and EGF-Like Factors Is Essential for Sustainable Activation of MAPK3/1 in Cumulus Cells During In Vitro Maturation of Porcine Cumulus Oocyte Complexes1

scientific article published on July 20, 2011

Possible involvement of phosphatidylinositol 3-kinase in the maintenance of metaphase II arrest in porcine oocytes matured in vitro

scientific article published in February 2010

Possible role for phosphatidylinositol 3-kinase in regulating meiotic maturation of bovine oocytes in vitro.

scientific article published in August 1998

Production of progesterone from de novo-synthesized cholesterol in cumulus cells and its physiological role during meiotic resumption of porcine oocytes.

scientific article published on 30 October 2002

Protein kinase C (PKC) increases TACE/ADAM17 enzyme activity in porcine ovarian somatic cells, which is essential for granulosa cell luteinization and oocyte maturation.

scientific article published in January 2014

Regulation of oocyte meiotic maturation by somatic cells.

scientific article

Roles of epidermal growth factor (EGF)-like factor in the ovulation process

scientific article published on 15 February 2016

Selective expression of KrasG12D in granulosa cells of the mouse ovary causes defects in follicle development and ovulation

scientific article published on June 2008

Sensing sperm via maternal immune system: a potential mechanism for controlling microenvironment for fertility in the cow

scientific article published on 01 August 2020

Synaptosomal-associated protein 25 gene expression is hormonally regulated during ovulation and is involved in cytokine/chemokine exocytosis from granulosa cells.

scientific article

TAF4b, a TBP associated factor, is required for oocyte development and function.

scientific article

TLR2/4 signaling pathway mediates sperm-induced inflammation in bovine endometrial epithelial cells in vitro

scientific article published on 17 April 2019

Targeted disruption of Nrg1 in granulosa cells alters the temporal progression of oocyte maturation

scientific article published on 20 March 2014

The Cell Type-Specific Expression of Lhcgr in Mouse Ovarian Cells: Evidence for a DNA-Demethylation-Dependent Mechanism

scientific article published on 01 May 2018

The Novel Pig In Vitro Maturation System to Improve Developmental Competence of Oocytes Derived from Atretic Non-Vascularized Follicle

scientific article

The acceleration of reproductive aging in Nrg1flox/flox ;Cyp19-Cre female mice.

scientific article published on 31 August 2017

The addition of calcium ion chelator, EGTA to thawing solution improves fertilizing ability in frozen-thawed boar sperm

article

The involvement of the Toll-like receptor family in ovulation.

scientific article published on 29 May 2008

The lncRNA Neat1 is required for corpus luteum formation and the establishment of pregnancy in a subpopulation of mice.

scientific article

The release of EGF domain from EGF-like factors by a specific cleavage enzyme activates the EGFR-MAPK3/1 pathway in both granulosa cells and cumulus cells during the ovulation process.

scientific article published on January 2012

The stromal fibrosis in aging ovary

scientific article published on 19 January 2018

Timing of MAP kinase inactivation effects on emission of polar body in porcine oocytes activated by Ca2+ ionophore.

scientific article published in January 2005

Toll-like receptors (TLR) 2 and 4 on human sperm recognize bacterial endotoxins and mediate apoptosis.

scientific article

Transgenic mice specifically expressing amphiregulin in white adipose tissue showed less adipose tissue mass.

scientific article published on 17 January 2018