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List of works by Paul A Trainor

A phenotype-driven ENU mutagenesis screen identifies novel alleles with functional roles in early mouse craniofacial development

scientific article

A quantitative method for defining high-arched palate using the Tcof1(+/-) mutant mouse as a model

scientific article published on 06 January 2016

Acrofacial Dysostosis, Cincinnati Type, a Mandibulofacial Dysostosis Syndrome with Limb Anomalies, Is Caused by POLR1A Dysfunction.

scientific article

Alcohol and aldehyde dehydrogenases: retinoid metabolic effects in mouse knockout models

scientific article

Alterations in retinoic acid signaling affect the development of the mouse coronary vasculature

scientific article published on 01 August 2018

Animal models for studying neural crest development: is the mouse different?

scientific article

Antagonism between retinoic acid and fibroblast growth factor signaling during limb development

scientific article published on 25 April 2013

Application of lacZ transgenic mice to cell lineage studies

scientific article

Application of lacZ transgenic mice to cell lineage studies

scientific article published on 01 January 2008

Balancing neural crest cell intrinsic processes with those of the microenvironment in Tcof1 haploinsufficient mice enables complete enteric nervous system formation

scientific article published on 6 January 2012

Bi-modal strategy of gastrulation in reptiles.

scientific article published on 19 June 2015

Captive Care, Raising, and Breeding of the Veiled Chameleon (Chamaeleo calyptratus).

scientific article published on 26 August 2015

Cell delamination in the mesencephalic neural fold and its implication for the origin of ectomesenchyme

scientific article

Cell grafting and labeling in postimplantation mouse embryos

scientific article

Cell grafting and labeling in postimplantation mouse embryos

scientific article published on 01 January 2008

Co-ordinated brain and craniofacial development depend upon Patched1/XIAP regulation of cell survival

scientific article

Cochleovestibular nerve development is integrated with migratory neural crest cells

scientific article

Comparative analysis of neural crest cell death, migration, and function during vertebrate embryogenesis

scientific article published on January 2004

Conservation and elaboration of Hox gene regulation during evolution of the vertebrate head

scientific article published in December 2000

Cranial nerve development requires co-ordinated Shh and canonical Wnt signaling

scientific article

Cranial paraxial mesoderm and neural crest cells of the mouse embryo: co-distribution in the craniofacial mesenchyme but distinct segregation in branchial arches

scientific article published on 01 August 1995

Cranial paraxial mesoderm: regionalisation of cell fate and impact on craniofacial development in mouse embryos.

scientific article published in September 1994

Craniofacial birth defects: The role of neural crest cells in the etiology and pathogenesis of Treacher Collins syndrome and the potential for prevention ⬇️

scientific article published on August 23, 2010

Craniofacial malformations: intrinsic vs extrinsic neural crest cell defects in Treacher Collins and 22q11 deletion syndromes.

scientific article

Craniofacial morphogenesis: a meeting in memory of Peter Thorogood

scientific article published in February 2000

Cux2 (Cutl2) integrates neural progenitor development with cell-cycle progression during spinal cord neurogenesis

scientific article

Cux2 functions downstream of Notch signaling to regulate dorsal interneuron formation in the spinal cord

scientific article published on July 2009

DAPI Staining of Whole-Mount Mouse Embryos or Fetal Organs

scientific article published on 01 October 2018

Defects in pathfinding by cranial neural crest cells in mice lacking the neuregulin receptor ErbB4

scientific journal article

Development and evolution of the pharyngeal apparatus

scientific article

Development. Riding the crest of the Wnt signaling wave

scientific article published on 01 August 2002

Development. The bills of qucks and duails

scientific article published in January 2003

Developmental Biology: We Are All Walking Mutants

scientific article published on 21 January 2016

Developmental biology - more dynamic than ever!

scientific article published in January 2018

Developmental biology is "Cruzing".

scientific article published in October 2004

Disrupting hedgehog and WNT signaling interactions promotes cleft lip pathogenesis

scientific article published on 03 March 2014

Dorsal patterning defects in the hindbrain, roof plate and skeleton in the dreher (dr(J)) mouse mutant.

scientific article published in June 2000

Dynamic expression of murine Cux2 in craniofacial, limb, urogenital and neuronal primordia.

scientific article published in October 2003

Dynamic imaging of mammalian neural tube closure

scientific article

Dynamic sex chromosomes in Old World chameleons (Squamata: Chamaeleonidae).

scientific article published on 18 January 2018

Embryonic bauplans and the developmental origins of facial diversity and constraint

scientific article (publication date: March 2014)

Face off against ROS: Tcof1/Treacle safeguards neuroepithelial cells and progenitor neural crest cells from oxidative stress during craniofacial development.

scientific article published on 2 August 2016

Facial dysostoses: Etiology, pathogenesis and management

scientific article

Facing up to the challenges of advancing Craniofacial Research

scientific article published on 28 March 2015

Filling in the phylogenetic gaps: Induction, migration, and differentiation of neural crest cells in a squamate reptile, the veiled chameleon (Chamaeleo calyptratus)

scientific article published on 29 April 2019

Flexibility of neural stem cells

scientific article

Follow-the-leader cell migration requires biased cell-cell contact and local microenvironmental signals

scientific article

Foxc2 is required for proper cardiac neural crest cell migration, outflow tract septation, and ventricle expansion

scientific article published on 01 December 2018

Foxc2CreERT2 knock-in mice mark stage-specific Foxc2-expressing cells during mouse organogenesis

scientific article published on 26 October 2016

Gadd45γ and Map3k4 interactions regulate mouse testis determination via p38 MAPK-mediated control of Sry expression

scientific article

Gene expression and regulation of hindbrain and spinal cord development.

scientific article published on January 2004

Gene transfer techniques in whole embryo cultured post-implantation mouse embryos

scientific article published in January 2014

Genetic interactions during hindbrain segmentation in the mouse embryo

scientific article

HGF-MET signals via the MLL-ETS2 complex in hepatocellular carcinoma

scientific article published on 24 June 2013

Hand/foot splitting and the 're-evolution' of mesopodial skeletal elements during the evolution and radiation of chameleons

scientific article

Hox genes, neural crest cells and branchial arch patterning

scientific article

Human COL2A1-directed SV40 T antigen expression in transgenic and chimeric mice results in abnormal skeletal development.

scientific article

Interaction between Foxc1 and Fgf8 during mammalian jaw patterning and in the pathogenesis of syngnathia.

scientific article

Interfering with Wnt signalling alters the periodicity of the segmentation clock.

scientific article published on 06 March 2009

Jawsfest: new perspectives on neural crest lineages and morphogenesis

scientific article published on 01 November 2003

Leucine-rich repeat-containing G-protein-coupled Receptor 5 marks short-term hematopoietic stem and progenitor cells during mouse embryonic development

scientific article

Lifting the Veil on Reptile Embryology: The Veiled Chameleon (Chamaeleo calyptratus) as a Model System to Study Reptilian Development.

scientific article

Loss of function mutation in the palmitoyl-transferase HHAT leads to syndromic 46,XY disorder of sex development by impeding Hedgehog protein palmitoylation and signaling

scientific article

MBTPS1/SKI-1/S1P proprotein convertase is required for ECM signaling and axial elongation during somitogenesis and vertebral development†.

scientific article published on 4 February 2015

Making headway: the roles of Hox genes and neural crest cells in craniofacial development

scientific article published on 14 April 2003

Mammalian neurogenesis requires Treacle-Plk1 for precise control of spindle orientation, mitotic progression, and maintenance of neural progenitor cells.

scientific article

Med23 Regulates Sox9 Expression during Craniofacial Development

scientific article published on 06 November 2020

Mef2c-F10N enhancer driven β-galactosidase (LacZ) and Cre recombinase mice facilitate analyses of gene function and lineage fate in neural crest cells

scientific article published on 17 March 2015

Mouse Embryo Culture for the Study of Neural Crest Cells

scientific article published on 01 January 2019

Mouse Models of Rare Craniofacial Disorders.

scientific article published on January 2015

Mutations in Hedgehog acyltransferase (Hhat) perturb Hedgehog signaling, resulting in severe acrania-holoprosencephaly-agnathia craniofacial defects

scientific article

Neural crest and placodes. Preface

scientific article

Neural crest cell evolution: how and when did a neural crest cell become a neural crest cell

scientific article published on 20 January 2015

Neural crest cell plasticity. size matters.

scientific article published on January 2006

Neural crest stem and progenitor cells

scientific article published on January 2006

Neural crest stem cells: discovery, properties and potential for therapy

scientific article published on 10 January 2012

New insights and changing paradigms in the regulation of vitamin A metabolism in development.

scientific article published on 16 February 2017

Non-cell-autonomous effects of Ret deletion in early enteric neurogenesis

scientific article

Organogenesis special issue - preface

scientific article published on 01 March 2015

Origins and plasticity of neural crest cells and their roles in jaw and craniofacial evolution

scientific article published on January 2003

Oscillations of the snail genes in the presomitic mesoderm coordinate segmental patterning and morphogenesis in vertebrate somitogenesis

scientific article published in March 2006

Patterning the cranial neural crest: hindbrain segmentation and Hox gene plasticity

scientific article

Perturbed development of cranial neural crest cells in association with reduced sonic hedgehog signaling underlies the pathogenesis of retinoic-acid-induced cleft palate

scientific article published on 04 October 2019

Plasticity in mouse neural crest cells reveals a new patterning role for cranial mesoderm

scientific article published in February 2000

Prevention of Treacher Collins syndrome craniofacial anomalies in mouse models via maternal antioxidant supplementation

scientific article published on 21 January 2016

Prevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function.

scientific article

RDH10 is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development

scientific journal article

RDH10 is the primary enzyme responsible for the first step of embryonic Vitamin A metabolism and retinoic acid synthesis.

scientific article

RDH10 oxidation of Vitamin A is a critical control step in synthesis of retinoic acid during mouse embryogenesis

scientific article

Rare syndromes of the head and face: mandibulofacial and acrofacial dysostoses

scientific article published on 10 February 2017

Rdh10 loss-of-function and perturbed retinoid signaling underlies the etiology of choanal atresia

scientific article

Rdh10 mutants deficient in limb field retinoic acid signaling exhibit normal limb patterning but display interdigital webbing

scientific article

Relations and interactions between cranial mesoderm and neural crest populations

scientific article (publication date: November 2005)

Retinoic Acid Activity in Undifferentiated Neural Progenitors Is Sufficient to Fulfill Its Role in Restricting Fgf8 Expression for Somitogenesis

scientific article published on 14 September 2015

Retinoic acid signaling promotes the cytoskeletal rearrangement of embryonic epicardial cells

scientific article published on 15 February 2018

Retinoic acid synthesis and autoregulation mediate zonal patterning of vestibular organs and inner ear morphogenesis

scientific article published on 14 July 2020

Ribosome biogenesis in skeletal development and the pathogenesis of skeletal disorders

scientific article

Ribosomopathies: Global process, tissue specific defects

scientific article

Role of morphogens in neural crest cell determination

scientific article

Role of the isthmus and FGFs in resolving the paradox of neural crest plasticity and prepatterning

scientific article published in February 2002

Signalling between the hindbrain and paraxial tissues dictates neural crest migration pathways

scientific article published in January 2002

Signals and switches in Mammalian neural crest cell differentiation ⬇️

scientific article (publication date: February 2013)

Somitogenesis: breaking new boundaries.

scientific article published on September 2003

Specification and patterning of neural crest cells during craniofacial development.

scientific article

Specification and segmentation of the paraxial mesoderm.

scientific article published on April 1994

Specification of neural crest cell formation and migration in mouse embryos.

scientific article

Synergy between Hoxa1 and Hoxb1: the relationship between arch patterning and the generation of cranial neural crest

scientific article published in August 2001

Tcof1 acts as a modifier of Pax3 during enteric nervous system development and in the pathogenesis of colonic aganglionosis

scientific article published on 2 January 2013

Tcof1/Treacle is required for neural crest cell formation and proliferation deficiencies that cause craniofacial abnormalities

scholarly article

The FaceBase Consortium: a comprehensive program to facilitate craniofacial research

scientific article

The Mediator Subunit, Med23 Is Required for Embryonic Survival and Regulation of Canonical WNT Signaling During Cranial Ganglia Development

scientific article published on 22 October 2020

The Mighty Chondrocyte: No Bones about It.

scientific article

The Roles of RNA Polymerase I and III Subunits Polr1c and Polr1d in Craniofacial Development and in Zebrafish Models of Treacher Collins Syndrome.

scientific article published on 22 July 2016

The Society for Craniofacial Genetics and Developmental Biology 37th annual meeting

scientific article published on 30 March 2015

The Society for Craniofacial Genetics and Developmental Biology 40th annual meeting

scientific article published in May 2018

The Society for Craniofacial Genetics and Developmental Biology 41st Annual Meeting

scientific article published on 22 February 2019

The Veiled Chameleon (Chamaeleo calyptratus Duméril and Duméril 1851): A Model for Studying Reptile Body Plan Development and Evolution

scientific article published on 26 August 2015

The developmental etiology and pathogenesis of Hirschsprung disease.

scientific article published on 22 March 2013

The retinaldehyde reductase DHRS3 is essential for preventing the formation of excess retinoic acid during embryonic development

scientific journal article

The role of kreisler in segmentation during hindbrain development

scientific article

The society for craniofacial genetics and developmental biology 38th annual meeting

scientific article published on 22 April 2016

The society for craniofacial genetics and developmental biology 39th annual meeting.

scientific article published on 7 February 2017

The therapeutic potential of stem cells in the treatment of craniofacial abnormalities

scientific article published on May 2004

The transcriptome of the veiled chameleon (Chamaeleo calyptratus): A resource for studying the evolution and development of vertebrates

scientific article published on 25 March 2019

Transcription factor TLX1 controls retinoic acid signaling to ensure spleen development

scientific article published on 23 May 2016

Transcriptional elongation factor elongin A regulates retinoic acid-induced gene expression during neuronal differentiation

scientific article

Treacher Collins syndrome

Treacher Collins syndrome: etiology, pathogenesis and prevention

scientific article

Treacher Collins syndrome: unmasking the role of Tcof1/treacle

scientific article

Ventral neural patterning in the absence of a Shh activity gradient from the floorplate.

scientific article published on 11 September 2017

Whole mount nuclear fluorescent imaging: convenient documentation of embryo morphology

scientific article

tp53-dependent and independent signaling underlies the pathogenesis and possible prevention of Acrofacial Dysostosis-Cincinnati type

scientific article published on 01 August 2018

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