List of works by Patrizia Lavia

A role for endogenous reverse transcriptase in tumorigenesis and as a target in differentiating cancer therapy.

scientific article

A role of p73 in mitotic exit.

scientific article published on 28 June 2005

Activation of human ribosomal genes by 5-azacytidine

article

Aurora-A and ch-TOG act in a common pathway in control of spindle pole integrity.

scientific article

Aurora-A inactivation causes mitotic spindle pole fragmentation by unbalancing microtubule-generated forces

scientific article published on 19 October 2011

Clonal inheritance of rRNA gene activity: Cytological evidence in human cells

article

Cloning of PC3B, a novel member of the PC3/BTG/TOB family of growth inhibitory genes, highly expressed in the olfactory epithelium

scientific article

Control of Aurora-A stability through interaction with TPX2.

scientific article published on 8 December 2010

Cytosine methylation transforms an E2F site in the retinoblastoma gene promoter into a binding site for the general repressor methylcytosine-binding protein 2 (MeCP2).

scientific article published on July 1999

Design and synthesis of 2-heterocyclyl-3-arylthio-1H-indoles as potent tubulin polymerization and cell growth inhibitors with improved metabolic stability.

scientific article published on 21 November 2011

Different effects of histone H1 on de novo DNA methylation in vitro depend on both the DNA base composition and the DNA methyltransferase.

scientific article published on September 1996

Effect of 5-azacytidine (5-azaC) on the induction of chromatid aberrations (CA) and sister-chromatid exchanges (SCE)

scientific article published on 01 May 1985

Identification of small molecule inhibitors of the Aurora-A/TPX2 complex

scientific article

Importin-β and CRM1 control a RANBP2 spatiotemporal switch essential for mitotic kinetochore function.

scientific article

Importin-β negatively regulates multiple aspects of mitosis including RANGAP1 recruitment to kinetochores.

scientific article published on 13 February 2012

Importin-β/karyopherin-β1 modulates mitotic microtubule function and taxane sensitivity in cancer cells via its nucleoporin-binding region

scientific article published on 06 September 2019

Localized RanGTP accumulation promotes microtubule nucleation at kinetochores in somatic mammalian cells

scientific article

Mammalian RanBP1 regulates centrosome cohesion during mitosis

scientific article (publication date: 15 August 2003)

Mitotic cell death induction by targeting the mitotic spindle with tubulin-inhibitory indole derivative molecules

scientific article published on February 2017

Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors

scientific article published on 22 July 2011

New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer

scientific article

New pyrrole derivatives with potent tubulin polymerization inhibiting activity as anticancer agents including hedgehog-dependent cancer

scientific article

Part of Ran is associated with AKAP450 at the centrosome: involvement in microtubule-organizing activity.

scientific article

Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy

scientific article published on 8 October 2015

RANBP1 localizes a subset of mitotic regulatory factors on spindle microtubules and regulates chromosome segregation in human cells.

scientific article

Ran control of mitosis in human cells: gradients and local signals

scientific article published in December 2010

Segmental chromosome aberrations converge on overexpression of mitotic spindle regulatory genes in high-risk neuroblastoma

article

Subcellular localization of the five members of the human steroid 5α-reductase family.

scientific article published on 21 March 2017

Targeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential.

scientific article

The GTPase RAN regulates multiple steps of the centrosome life cycle.

scientific article

The GTPase Ran: regulation of cell life and potential roles in cell transformation.

scientific article published on May 2008

The Mitotic Apparatus and Kinetochores in Microcephaly and Neurodevelopmental Diseases

scientific article published on 24 December 2019

Toward highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitors

scientific article published on 27 December 2012

Two E2F sites control growth-regulated and cell cycle-regulated transcription of the Htf9-a/RanBP1 gene through functionally distinct mechanisms.

scientific article published on April 1999

Visualization of human karyopherin beta-1/importin beta-1 interactions with protein partners in mitotic cells by co-immunoprecipitation and proximity ligation assays

scientific article

p38 MAPK differentially controls NK activating ligands at transcriptional and post-transcriptional level on multiple myeloma cells.

scientific article published on 2 December 2016

p53 displacement from centrosomes and p53-mediated G1 arrest following transient inhibition of the mitotic spindle.

scientific article published on 28 February 2001

p53 localization at centrosomes during mitosis and postmitotic checkpoint are ATM-dependent and require serine 15 phosphorylation.

scientific article published on 4 June 2004

p53-independent apoptosis and p53-dependent block of DNA rereplication following mitotic spindle inhibition in human cells.

scientific article

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