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List of works by Sara Duarte-Silva

Absence of Tau triggers age-dependent sciatic nerve morphofunctional deficits and motor impairment

scientific article published on 8 January 2016

Chronic treatment with 17-DMAG improves balance and coordination in a new mouse model of Machado-Joseph disease

scientific article published on April 2014

Citalopram Reduces Aggregation of ATXN3 in a YAC Transgenic Mouse Model of Machado-Joseph Disease

scientific article published on 04 September 2018

Combined therapy with m-TOR-dependent and -independent autophagy inducers causes neurotoxicity in a mouse model of Machado-Joseph disease

scientific article published on 18 November 2015

Deficiency in classical nonhomologous end-joining-mediated repair of transcribed genes is linked to SCA3 pathogenesis

scientific article published on 23 March 2020

Differential mtDNA damage patterns in a transgenic mouse model of Machado-Joseph disease (MJD/SCA3).

scientific article published on 8 July 2014

Discovery of Therapeutic Approaches for Polyglutamine Diseases: A Summary of Recent Efforts

scientific article published on 21 November 2016

Dominant negative effect of polyglutamine expansion perturbs normal function of ataxin-3 in neuronal cells

scientific article

IP3 R2 null mice display a normal acquisition of somatic and neurological development milestones

scientific article published on 12 March 2020

Limited Effect of Chronic Valproic Acid Treatment in a Mouse Model of Machado-Joseph Disease

scientific article

Lithium chloride therapy fails to improve motor function in a transgenic mouse model of Machado-Joseph disease

scientific article published in December 2014

Monoamine deficits in the brain of methyl-CpG binding protein 2 null mice suggest the involvement of the cerebral cortex in early stages of Rett syndrome

scientific article published on 13 July 2010

Motor uncoordination and neuropathology in a transgenic mouse model of Machado-Joseph disease lacking intranuclear inclusions and ataxin-3 cleavage products

scientific article published on 25 May 2010

Neuroprotective effects of creatine in the CMVMJD135 mouse model of spinocerebellar ataxia type 3.

scientific article published on 23 March 2018

Neurotoxic effects of MPTP on mouse cerebral cortex: Modulation of neuroinflammation as a neuroprotective strategy

scientific article published on 13 February 2019

Pharmacological Therapies for Machado-Joseph Disease.

scientific article published in January 2018

Preclinical Evidence Supporting Early Initiation of Citalopram Treatment in Machado-Joseph Disease

scientific article published on 01 September 2018

Selective impact of Tau loss on nociceptive primary afferents and pain sensation

Serotonergic signalling suppresses ataxin 3 aggregation and neurotoxicity in animal models of Machado-Joseph disease

scientific article

Tauroursodeoxycholic Acid Improves Motor Symptoms in a Mouse Model of Parkinson's Disease

article