List of works - Elizabeth J. New

A FRET-based ratiometric redox probe for detecting oxidative stress by confocal microscopy, FLIM and flow cytometry

scientific article published in July 2015

A Fluorogenic Probe for Cell Surface Phosphatidylserine Using an Intramolecular Indicator Displacement Sensing Mechanism

scientific article published on 13 December 2018

A Fluorogenic Probe for Cell Surface Phosphatidylserine Using an Intramolecular Indicator Displacement Sensing Mechanism

A cell-permeable gadolinium contrast agent for magnetic resonance imaging of copper in a Menkes disease model

scientific article

A cobalt(ii) complex with unique paraSHIFT responses to anions

scientific article published on 13 March 2017

A fluorescent naphthalimide NADH mimic for continuous and reversible sensing of cellular redox state

scientific article published on 01 February 2020

A library-screening approach for developing a fluorescence sensing array for the detection of metal ions

scientific article

A mechanistic study of the dynamic quenching of the excited state of europium(iii) and terbium(iii) macrocyclic complexes by charge- or electron transfer

article

A novel flavin derivative reveals the impact of glucose on oxidative stress in adipocytes

scientific article published on August 2014

A ratiometric fluorescent sensor for the mitochondrial copper pool

scientific article published on 23 August 2016

A ratiometric iron probe enables investigation of iron distribution within tumour spheroids

scientific article published on 16 April 2018

A reversible fluorescent probe for monitoring Ag(I) ions

scientific article published on 01 July 2018

A selective reaction-based fluorescent probe for detecting cobalt in living cells

scientific article published on 24 April 2012

Activity-Based Sensing: Achieving Chemical Selectivity through Chemical Reactivity

scientific article published on 01 January 2020

Bioinspired Small-Molecule Tools for the Imaging of Redox Biology

scientific article published on 12 February 2019

Cell-penetrating metal complex optical probes: targeted and responsive systems based on lanthanide luminescence

scientific article

Cellular uptake and distribution of cobalt complexes of fluorescent ligands

scientific article

Comparative study of the constitution and chiroptical properties of emissive terbium and europium complexes with a common tetraazatriphenylene sensitiser; the nature of the sensitiser determines quenching sensitivity and cellular uptake

scientific article published on January 2009

Copper regulates cyclic-AMP-dependent lipolysis

scientific article

Critical evaluation of five emissive europium(III) complexes as optical probes: correlation of cytotoxicity, anion and protein affinity with complex structure, stability and intracellular localisation profile

scientific article published on 21 April 2008

Definition of the uptake mechanism and sub-cellular localisation profile of emissive lanthanide complexes as cellular optical probes

Development of responsive lanthanide probes for cellular applications

scientific article published on 31 October 2009

Enantioselective binding of a lanthanide(iii) complex to human serum albumin studied by 1H STD NMR techniques

scientific article published on 03 June 2011

Enantioselective regulation of a metal complex in reversible binding to serum albumin: dynamic helicity inversion signalled by circularly polarised luminescence

article

Expanding the breadth of 4-amino-1,8-naphthalimide photophysical properties through substitution of the naphthalimide core

scientific article published on 8 February 2018

Fluorescent analogues of quinoline reveal amine ligand loss from cis and trans platinum(II) complexes in cancer cells

scientific article

Fluorescent probes for the simultaneous detection of multiple analytes in biology

scientific article

Fluorescent sensing arrays for cations and anions

scientific article

Fluorescent sensing of monofunctional platinum species

scientific article published in April 2015

Harnessing the Potential of Small Molecule Intracellular Fluorescent Sensors

Hypoxia-Responsive Cobalt Complexes in Tumor Spheroids: Laser Ablation Inductively Coupled Plasma Mass Spectrometry and Magnetic Resonance Imaging Studies

scientific article published on 2 August 2017

Identification of emissive lanthanide complexes suitable for cellular imaging that resist quenching by endogenous anti-oxidants

scientific article

Imaging metals in biology: balancing sensitivity, selectivity and spatial resolution

scientific article

Imaging mitochondrial hydrogen peroxide in living cells

scientific article published on January 2015

Interactions of cisplatin and the copper transporter CTR1 in human colon cancer cells

scientific article published on 17 May 2017

Investigations using fluorescent ligands to monitor platinum(IV) reduction and platinum(II) reactions in cancer cells

scientific article published on 6 March 2009

Light-activated regulation of cofilin dynamics using a photocaged hydrogen peroxide generator

scientific article

Mechanisms of cell uptake and toxicity of the anticancer drug cisplatin

scientific article published in November 2014

Mitochondrially targeted fluorescent redox sensors

scientific article published on April 2017

Mitochondrially targeted redox probe reveals the variations in oxidative capacity of the haematopoietic cells

scientific article published on June 2015

On the outside looking in: redefining the role of analytical chemistry in the biosciences

scientific article published on 22 February 2016

Pattern recognition of toxic metal ions using a single-probe thiocoumarin array

scientific article published on 01 December 2018

Platinum-oxazoline complexes as anti-cancer agents: syntheses, characterisation and initial biological studies

article

Promising strategies for Gd-based responsive magnetic resonance imaging contrast agents

scientific article

Reaction-based fluorescent probes for selective imaging of hydrogen sulfide in living cells

scientific article published on 15 June 2011

Reversible Fluorescent Probes for Biological Redox States

scientific article

Selective and Reversible Approaches Toward Imaging Redox Signaling Using Small-Molecule Probes

scientific article published on 26 November 2015

Studies of Hematopoietic Cell Differentiation with a Ratiometric and Reversible Sensor of Mitochondrial Reactive Oxygen Species

scientific article

Studies of the labile lead pool using a rhodamine-based fluorescent probe

scientific article published on 28 April 2020

Synthesis and Characterization of Metal Complexes with Schiff Base Ligands

Tailoring the properties of a hypoxia-responsive 1,8-naphthalimide for imaging applications

scientific article published on 5 January 2018

The influence of the ethane-1,2-diamine ligand on the activity of a monofunctional platinum complex

scientific article published on 29 July 2017

The mechanism of cell uptake for luminescent lanthanide optical probes: the role of macropinocytosis and the effect of enhanced membrane permeability on compartmentalisation

scientific article published on 14 January 2009

The nature of the sensitiser substituent determines quenching sensitivity and protein affinity and influences the design of emissive lanthanide complexes as optical probes for intracellular use.

scientific article

Thimerosal neurotoxicity is associated with glutathione depletion: protection with glutathione precursors

scientific article

Tools to study distinct metal pools in biology ⬇️

scientific article published on October 17, 2012

Two-photon microscopy study of the intracellular compartmentalisation of emissive terbium complexes and their oligo-arginine and oligo-guanidinium conjugates

scientific article published on 22 April 2008

Versatile naphthalimide tetrazines for fluorogenic bioorthogonal labelling

scientific article published in 2021

Versatility of Terpyridine-Functionalised Aryl Tetrazoles: Photophysical Properties, Ratiometric Sensing of Zinc Cations and Sensitisation of Lanthanide Luminescence

What has fluorescent sensing told us about copper and brain malfunction?

scientific article

List of works by Elizabeth J. New

A FRET-based ratiometric redox probe for detecting oxidative stress by confocal microscopy, FLIM and flow cytometry

A Fluorogenic Probe for Cell Surface Phosphatidylserine Using an Intramolecular Indicator Displacement Sensing Mechanism

A Fluorogenic Probe for Cell Surface Phosphatidylserine Using an Intramolecular Indicator Displacement Sensing Mechanism

A cell-permeable gadolinium contrast agent for magnetic resonance imaging of copper in a Menkes disease model

A cobalt(ii) complex with unique paraSHIFT responses to anions

A fluorescent naphthalimide NADH mimic for continuous and reversible sensing of cellular redox state

A library-screening approach for developing a fluorescence sensing array for the detection of metal ions

A mechanistic study of the dynamic quenching of the excited state of europium(iii) and terbium(iii) macrocyclic complexes by charge- or electron transfer

A novel flavin derivative reveals the impact of glucose on oxidative stress in adipocytes

A ratiometric fluorescent sensor for the mitochondrial copper pool

A ratiometric iron probe enables investigation of iron distribution within tumour spheroids

A reversible fluorescent probe for monitoring Ag(I) ions

A selective reaction-based fluorescent probe for detecting cobalt in living cells

Activity-Based Sensing: Achieving Chemical Selectivity through Chemical Reactivity

Bioinspired Small-Molecule Tools for the Imaging of Redox Biology

Cell-penetrating metal complex optical probes: targeted and responsive systems based on lanthanide luminescence

Cellular uptake and distribution of cobalt complexes of fluorescent ligands

Comparative study of the constitution and chiroptical properties of emissive terbium and europium complexes with a common tetraazatriphenylene sensitiser; the nature of the sensitiser determines quenching sensitivity and cellular uptake

Copper regulates cyclic-AMP-dependent lipolysis

Critical evaluation of five emissive europium(III) complexes as optical probes: correlation of cytotoxicity, anion and protein affinity with complex structure, stability and intracellular localisation profile

Definition of the uptake mechanism and sub-cellular localisation profile of emissive lanthanide complexes as cellular optical probes

Development of responsive lanthanide probes for cellular applications

Enantioselective binding of a lanthanide(iii) complex to human serum albumin studied by 1H STD NMR techniques

Enantioselective regulation of a metal complex in reversible binding to serum albumin: dynamic helicity inversion signalled by circularly polarised luminescence

Expanding the breadth of 4-amino-1,8-naphthalimide photophysical properties through substitution of the naphthalimide core

Fluorescent analogues of quinoline reveal amine ligand loss from cis and trans platinum(II) complexes in cancer cells

Fluorescent probes for the simultaneous detection of multiple analytes in biology

Fluorescent sensing arrays for cations and anions

Fluorescent sensing of monofunctional platinum species

Harnessing the Potential of Small Molecule Intracellular Fluorescent Sensors

Hypoxia-Responsive Cobalt Complexes in Tumor Spheroids: Laser Ablation Inductively Coupled Plasma Mass Spectrometry and Magnetic Resonance Imaging Studies

Identification of emissive lanthanide complexes suitable for cellular imaging that resist quenching by endogenous anti-oxidants

Imaging metals in biology: balancing sensitivity, selectivity and spatial resolution

Imaging mitochondrial hydrogen peroxide in living cells

Interactions of cisplatin and the copper transporter CTR1 in human colon cancer cells

Investigations using fluorescent ligands to monitor platinum(IV) reduction and platinum(II) reactions in cancer cells

Light-activated regulation of cofilin dynamics using a photocaged hydrogen peroxide generator

Mechanisms of cell uptake and toxicity of the anticancer drug cisplatin

Mitochondrially targeted fluorescent redox sensors

Mitochondrially targeted redox probe reveals the variations in oxidative capacity of the haematopoietic cells

On the outside looking in: redefining the role of analytical chemistry in the biosciences

Pattern recognition of toxic metal ions using a single-probe thiocoumarin array

Platinum-oxazoline complexes as anti-cancer agents: syntheses, characterisation and initial biological studies

Promising strategies for Gd-based responsive magnetic resonance imaging contrast agents

Reaction-based fluorescent probes for selective imaging of hydrogen sulfide in living cells

Reversible Fluorescent Probes for Biological Redox States

Selective and Reversible Approaches Toward Imaging Redox Signaling Using Small-Molecule Probes

Studies of Hematopoietic Cell Differentiation with a Ratiometric and Reversible Sensor of Mitochondrial Reactive Oxygen Species

Studies of the labile lead pool using a rhodamine-based fluorescent probe

Synthesis and Characterization of Metal Complexes with Schiff Base Ligands

Tailoring the properties of a hypoxia-responsive 1,8-naphthalimide for imaging applications

The influence of the ethane-1,2-diamine ligand on the activity of a monofunctional platinum complex

The mechanism of cell uptake for luminescent lanthanide optical probes: the role of macropinocytosis and the effect of enhanced membrane permeability on compartmentalisation

The nature of the sensitiser substituent determines quenching sensitivity and protein affinity and influences the design of emissive lanthanide complexes as optical probes for intracellular use.

Thimerosal neurotoxicity is associated with glutathione depletion: protection with glutathione precursors

Tools to study distinct metal pools in biology ⬇️

Two-photon microscopy study of the intracellular compartmentalisation of emissive terbium complexes and their oligo-arginine and oligo-guanidinium conjugates

Versatile naphthalimide tetrazines for fluorogenic bioorthogonal labelling

Versatility of Terpyridine-Functionalised Aryl Tetrazoles: Photophysical Properties, Ratiometric Sensing of Zinc Cations and Sensitisation of Lanthanide Luminescence

What has fluorescent sensing told us about copper and brain malfunction?