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List of works by Donald Pfaff

Abolition of sex-dependent effects of prenatal exposure to diethylstilbestrol on emotional behavior in estrogen receptor-alpha knockout mice

scientific article published in July 2006

Acute stress and hippocampal histone H3 lysine 9 trimethylation, a retrotransposon silencing response

scientific article

Agonistic behavior in males and females: effects of an estrogen receptor beta agonist in gonadectomized and gonadally intact mice

scientific article

An estrogen-dependent four-gene micronet regulating social recognition: a study with oxytocin and estrogen receptor-alpha and -beta knockout mice

scholarly article

Analyses of rapid estrogen actions on rat ventromedial hypothalamic neurons

scientific article published on 24 March 2016

Angiogenesis in association with the migration of gonadotropic hormone-releasing hormone (GnRH) systems in embryonic mice, early human embryos and in a fetus with Kallmann's syndrome

scientific article published in January 2002

Arousal of cerebral cortex electroencephalogram consequent to high-frequency stimulation of ventral medullary reticular formation

scholarly article

Arousing properties of the vulvar epithelium

scientific article published on August 2006

Brain mast cells link the immune system to anxiety-like behavior

scientific article

CNS arousal mechanisms bearing on sex and other biologically regulated behaviors

scientific article published on June 2006

Calcium flux in neuroblastoma cells is a coupling mechanism between non-genomic and genomic modes of estrogens.

scientific article published on 11 July 2005

Can distinctly different rapid estrogen actions share a common mechanistic step?

scientific article published on 26 February 2018

Clitoral sexual arousal: an immunocytochemical and innervation study of the clitoris

scientific article published in June 2008

Clitoral sexual arousal: neuronal tracing study from the clitoris through the spinal tracts

scientific article published on 15 August 2008

Colocalization of connexin 36 and corticotropin-releasing hormone in the mouse brain

scientific article

Comparing quantitative trait Loci and gene expression data

scientific article

Concepts and mechanisms of generalized central nervous system arousal

scientific article published on January 2008

Deconstructing and reconstructing theory of mind

scientific article

Definition of arousal and mechanistic studies in intact and brain-damaged mice

scientific article published on March 2009

Development of a sexually differentiated behavior and its underlying CNS arousal functions

scientific article published on January 2007

Distinct behavioral phenotypes in male mice lacking the thyroid hormone receptor α1 or β isoforms

scientific article published on April 6, 2013

Effect of ER-beta gene disruption on estrogenic regulation of anxiety in female mice

scientific article published on 29 October 2008

Effects of chronic social defeat on behavioral and neural correlates of sociality: Vasopressin, oxytocin and the vasopressinergic V1b receptor

scientific article published on March 22, 2011

Effects of estrogen receptor alpha and beta gene deletion on estrogenic induction of progesterone receptors in the locus coeruleus in female mice

scientific article published on 24 June 2009

Environmental stress and transposon transcription in the mammalian brain

scientific article published on March 2013

Estradiol differentially regulates lipocalin-type prostaglandin D synthase transcript levels in the rodent brain: Evidence from high-density oligonucleotide arrays and in situ hybridization

scientific article

Estradiol modulates behavioral arousal and induces changes in gene expression profiles in brain regions involved in the control of vigilance

scientific article published on 5 February 2009

Estradiol modulation of phenylephrine-induced excitatory responses in ventromedial hypothalamic neurons of female rats

scholarly article

Estradiol regulates responsiveness of the dorsal premammillary nucleus of the hypothalamus and affects fear- and anxiety-like behaviors in female rats

scientific article published on 24 May 2014

Estradiol regulation of lipocalin-type prostaglandin D synthase promoter activity: evidence for direct and indirect mechanisms

scientific article published on March 2010

Estrogen and thyroid hormone receptor interactions: physiological flexibility by molecular specificity

scientific article

Estrogen evokes a rapid effect on intracellular calcium in neurons characterized by calcium oscillations in the arcuate nucleus

scientific article published in June 2007

Estrogen facilitates fear conditioning and increases corticotropin-releasing hormone mRNA expression in the central amygdala in female mice

scientific article published on 3 August 2005

Estrogen increases locomotor activity in mice through estrogen receptor alpha: specificity for the type of activity

scientific article

Estrogen receptor beta (ERbeta) protein levels in neurons depend on estrogen receptor alpha (ERalpha) gene expression and on its ligand in a brain region-specific manner

scientific article

Estrogen receptor-beta gene disruption potentiates estrogen-inducible aggression but not sexual behaviour in male mice

scientific article

Estrogen receptor-beta regulates transcript levels for oxytocin and arginine vasopressin in the hypothalamic paraventricular nucleus of male mice

scientific article published in December 2002

Estrogen receptor-mediated transcription involves the activation of multiple kinase pathways in neuroblastoma cells.

scientific article published on 10 October 2013

Estrogen receptors alpha and beta mediate different aspects of the facilitatory effects of female cues on male risk taking

scientific article published on 18 April 2008

Estrogen-induced sexual incentive motivation, proceptivity and receptivity depend on a functional estrogen receptor alpha in the ventromedial nucleus of the hypothalamus but not in the amygdala

scientific article

Estrogenic regulation of gene and protein expression within the amygdala of female mice

scientific article

Etiologies underlying sex differences in Autism Spectrum Disorders

scientific article

Exercise reinforcement, stress, and β-endorphins: an initial examination of exercise in anabolic-androgenic steroid dependence

scientific article

Functional genomics of sex hormone-dependent neuroendocrine systems: specific and generalized actions in the CNS.

scientific article published on January 2006

Gene expression in neuroendocrine cells during the critical period for sexual differentiation of the brain

scientific article published on January 1, 2010

Gene-hormone-environment interactions in the regulation of aggressive responses: elegant analysis of complex behavior

scientific article published on 02 October 2007

Genes for sex hormone receptors controlling mouse aggression.

scientific article

Genes, odours and the recognition of parasitized individuals by rodents

scientific article

Genetic influences on aggressive behaviors and arousability in animals.

scientific article

Genotype/age interactions on aggressive behavior in gonadally intact estrogen receptor beta knockout (betaERKO) male mice

scientific article published in May 2002

Histamine-induced excitatory responses in mouse ventromedial hypothalamic neurons: ionic mechanisms and estrogenic regulation

scientific article published on 17 October 2007

Histaminergic responses by hypothalamic neurons that regulate lordosis and their modulation by estradiol

scientific article

Histone modifications proposed to regulate sexual differentiation of brain and behavior

scientific article published on 10 September 2010

How generalized CNS arousal strengthens sexual arousal (and vice versa).

scientific article

Immunocytochemical characterization of pacinian-like corpuscles in the labia minora of prepubertal girls.

scientific article published on 9 September 2011

Immunolocalization of Estrogen Receptor β in the Mouse Brain: Comparison with Estrogen Receptor α

scientific article published on May 1, 2003

Impact of Thyroid Hormones on Estrogen Receptor α-Dependent Transcriptional Mechanisms in Ventromedial Hypothalamus and Preoptic Area

scientific article published on 13 March 2015

Implications of prenatal steroid perturbations for neurodevelopment, behavior, and autism

scientific article

Inadvertent social information and the avoidance of parasitized male mice: a role for oxytocin.

scholarly article

Inhibition of neuronal phenotype by PTEN in PC12 cells

scientific journal article

Innervation of the labia minora of prepubertal girls

scientific article published on 21 May 2010

Integration of steroid hormone initiated membrane action to genomic function in the brain.

scientific article

Interactions between estrogen effects and hunger effects in ovariectomized female mice. I. Measures of arousal

scientific article

Laternal nicotine exposure increases nicotine preference in periadolescent male but not female C57B1/6J mice

scientific article published in February 2003

Mechanisms underlying an ability to behave ethically

scientific article published in May 2008

Mechanisms underlying sexual and affiliative behaviors of mice: relation to generalized CNS arousal.

scientific article published on December 2006

Membrane-initiated actions of estrogens in neuroendocrinology: emerging principles.

scientific article published on 3 October 2006

Metabolic pathways that mediate inhibition of hypothalamic neurons by glucose.

scientific article published in January 2004

Microparticle-based delivery of oxytocin receptor antisense DNA in the medial amygdala blocks social recognition in female mice

scholarly article

Mouse model of diffuse brain damage following anoxia, evaluated by a new assay of generalized arousal

scientific article

Non-genomic actions of estrogens and their interaction with genomic actions in the brain.

scientific article published on October 2007

Nonmammalian gonadotropin-releasing hormone molecules in the brain of promoter transgenic rats

scientific article

Oestrogen receptor expression and neuronal nitric oxide synthase in the clitoris and preputial gland structures of mice

scientific article

Oestrogen receptors and their relation to neural receptive tissue of the labia minora

scientific article published on June 2008

Olfactory-mediated parasite recognition and avoidance: linking genes to behavior.

scientific article published in September 2004

Oxytocin, vasopressin and estrogen receptor gene expression in relation to social recognition in female mice.

scientific article

Perspective: micoarrays and differential display PCR-tools for studying transcript levels of genes in neuroendocrine systems

scientific article published on 01 June 2002

Phase-Amplitude Coupling in Spontaneous Mouse Behavior

scientific article

Potentiation of genomic actions of estrogen by membrane actions in mcf-7 cells and the involvement of protein kinase C activation

scientific article published on August 2005

RNAi-mediated silencing of estrogen receptor {alpha} in the ventromedial nucleus of hypothalamus abolishes female sexual behaviors.

scientific article

Rapid estrogen actions on ion channels: A survey in search for mechanisms

scientific article published on 29 February 2016

Rapid increases in immature synapses parallel estrogen-induced hippocampal learning enhancements

scientific article

Recognition and avoidance of the odors of parasitized conspecifics and predators: differential genomic correlates

scientific article

Reduction of lipocalin-type prostaglandin D synthase in the preoptic area of female mice mimics estradiol effects on arousal and sex behavior

scientific article

Regulation of hippocampal H3 histone methylation by acute and chronic stress.

scientific article

Relationship of arousal to circadian anticipatory behavior: ventromedial hypothalamus: one node in a hunger-arousal network

scientific article published on 26 October 2009

Reproductive behaviors: new developments in concepts and in molecular mechanisms progress in brain research, Luciano Martini, editor, January 19, 2010.

scientific article published on January 2010

Retinoid-related receptor (ROR) alpha mRNA expression is altered in the brain of male mice lacking all ligand-binding thyroid hormone receptor (TR) isoforms

scientific article

Scale invariance in the dynamics of spontaneous behavior

scientific article

Self-assessment of anatomy, sexual sensitivity, and function of the labia and vagina

scientific article

Sex differences in estrogenic regulation of neuronal activity in neonatal cultures of ventromedial nucleus of the hypothalamus

scientific article

Sex on the brain

scientific article published in October 2009

Sex-specific gene-environment interactions underlying ASD-like behaviors

scientific article published on 23 January 2017

Significance of topical estrogens to labial fusion and vaginal introital integrity

scientific article published on October 2006

Silencing Estrogen Receptor-α with siRNA in the Intact Rodent Brain

scientific article published on January 2016

Silencing of estrogen receptor alpha in the ventromedial nucleus of hypothalamus leads to metabolic syndrome.

scholarly article

Statistical analysis of hormonal influences on arousal measures in ovariectomized female mice

scientific article published on December 2002

Steroidal/neuropeptide interactions in hypothalamus and amygdala related to social anxiety.

scientific article published on January 2008

Stomach ghrelin-secreting cells as food-entrainable circadian clocks

scientific article

Stress and corticosteroids regulate rat hippocampal mitochondrial DNA gene expression via the glucocorticoid receptor.

scientific article published on 25 July 2016

Stress and the dynamic genome: Steroids, epigenetics, and the transposome

scientific article published on 10 November 2014

Success of treatment modalities for labial fusion: a retrospective evaluation of topical and surgical treatments

scientific article published on August 2009

Temporal and spatial quantitation of nesting and mating behaviors among mice housed in a semi-natural environment

scientific article published in November 2002

Terminal innervation of female genitalia, cutaneous sensory receptors of the epithelium of the labia minora

scientific article published on 2 February 2015

Terminal innervation of the male genitalia, cutaneous sensory receptors of the male foreskin

scientific article published on 2 February 2015

The diagnostic dilemma of pathological appearance and performance enhancing drug use

scientific article

The membrane actions of estrogens can potentiate their lordosis behavior-facilitating genomic actions

scholarly article

The role of the estrogen receptor alpha in the medial amygdala and ventromedial nucleus of the hypothalamus in social recognition, anxiety and aggression

scientific article published on 23 February 2010

The role of the estrogen receptor α in the medial preoptic area in sexual incentive motivation, proceptivity and receptivity, anxiety, and wheel running in female rats

scientific article published on April 21, 2012

Thyroid hormone can increase estrogen-mediated transcription from a consensus estrogen response element in neuroblastoma cells.

scientific article

Two forces for arousal: Pitting hunger versus circadian influences and identifying neurons responsible for changes in behavioral arousal.

scholarly article

Vasopressin stimulates ventromedial hypothalamic neurons via oxytocin receptors in oxytocin gene knockout male and female mice

scientific article published on 2 November 2004

siRNA silencing of estrogen receptor-α expression specifically in medial preoptic area neurons abolishes maternal care in female mice

scientific article published on September 17, 2012