List of works - Florian Kern

Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects

scientific article

Protection from cytomegalovirus after transplantation is correlated with immediate early 1-specific CD8 T cells

scientific article

T-cell epitope mapping by flow cytometry

scientific article published on August 1, 1998

Diagnosis of childhood tuberculosis and host RNA expression in Africa

scientific article published in May 2014

Detection of tuberculosis in HIV-infected and -uninfected African adults using whole blood RNA expression signatures: a case-control study

scientific article (publication date: October 2013)

Cytomegalovirus (CMV) phosphoprotein 65 makes a large contribution to shaping the T cell repertoire in CMV-exposed individuals

scientific article published on 31 May 2002

Target structures of the CD8(+)-T-cell response to human cytomegalovirus: the 72-kilodalton major immediate-early protein revisited.

scientific article published on October 1999

Putative immunodominant human immunodeficiency virus-specific CD8(+) T-cell responses cannot be predicted by major histocompatibility complex class I haplotype

scientific article

Standardizing Flow Cytometry Immunophenotyping Analysis from the Human ImmunoPhenotyping Consortium

scientific article

Distribution of human CMV-specific memory T cells among the CD8pos. subsets defined by CD57, CD27, and CD45 isoforms

scientific article published in September 1999

CMV and Immunosenescence: from basics to clinics

scientific article published on 31 October 2012

Polyfunctional T cells accumulate in large human cytomegalovirus-specific T cell responses

scientific article published on 9 November 2011

Cytomegalovirus infection induces the accumulation of short-lived, multifunctional CD4+CD45RA+CD27+ T cells: the potential involvement of interleukin-7 in this process

scientific article published on 7 January 2011

Loss of receptor on tuberculin-reactive T-cells marks active pulmonary tuberculosis

scientific article published on 15 August 2007

Mechanisms of human cytomegalovirus (HCMV) (re)activation and its impact on organ transplant patients.

scientific article

Measuring Ag-specific immune responses: understanding immunopathogenesis and improving diagnostics in infectious disease, autoimmunity and cancer

scientific article

Mapping T cell epitopes by flow cytometry

scientific article

Circulating Plasma microRNAs can differentiate Human Sepsis and Systemic Inflammatory Response Syndrome (SIRS).

scientific article published on 20 June 2016

SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19

scientific article published on 29 July 2020

Age-associated increase of low-avidity cytomegalovirus-specific CD8+ T cells that re-express CD45RA

scientific article published on May 2013

Hyperprocalcitonemia in Patients with Noninfectious SIRS and Pulmonary Dysfunction Associated with Cardiopulmonary Bypass

scientific article published on July 1, 1998

Immunosenescence and Cytomegalovirus: where do we stand after a decade?

scientific article published on 7 September 2010

High levels of CMV-IE-1-specific memory T cells are associated with less alloimmunity and improved renal allograft function

scientific article published on 24 November 2008

Random screening of proteins for HLA-A0201-binding nine-amino acid peptides is not sufficient for identifying CD8 T cell epitopes recognized in the context of HLA-A0201.

scientific article published in June 2004

Analysis of antigen-specific T-cell responses with synthetic peptides--what kind of peptide for which purpose?

scientific article

The enigma of CD57+CD28- T cell expansion--anergy or activation?

scientific article published in April 1996

CMV-specific central memory T cells reside in bone marrow

scientific article published in November 2007

How flow cytometry is changing the study of TB immunology and clinical diagnosis

scientific article

Report from the second cytomegalovirus and immunosenescence workshop

scientific article published on 28 October 2011

Confirmation of Mycobacterium tuberculosis infection by flow cytometry after ex vivo incubation of peripheral blood T cells with an ESAT-6-derived peptide pool

scientific article published in July 2004

A novel cytomegalovirus-induced regulatory-type T-cell subset increases in size during older life and links virus-specific immunity to vascular pathology

scientific article

Secondary heterologous dengue infection risk: Disequilibrium between immune regulation and inflammation?

scientific article published on 10 February 2010

CD45RA(bright)/CD11a(bright) CD8+ T cells: effector T cells

scientific article published in December 1998

Cell-mediated immunity to human CMV infection: a brief overview

scientific article published on May 6, 2014

Delayed-type hypersensitivity-like mechanisms dominate late acute rejection episodes in renal allograft recipients

scientific article

Massive elevation of procalcitonin plasma levels in the absence of infection in kidney transplant patients treated with pan-T-cell antibodies

scientific article published on 01 June 2001

Enumeration of antigen-specific CD8+ T lymphocytes by single-platform, HLA tetramer-based flow cytometry: a European multicenter evaluation

scientific article published on 01 November 2004

HLA type-independent generation of antigen-specific T cells for adoptive immunotherapy

scientific article published in July 2005

NS1 specific CD8+ T-cells with effector function and TRBV11 dominance in a patient with parvovirus B19 associated inflammatory cardiomyopathy

scientific article

Detection of antigen-specific T cells by cytokine flow cytometry: the use of whole blood may underestimate frequencies

scientific article published in December 2003

Tuberculin-specific T cells are reduced in active pulmonary tuberculosis compared to LTBI or status post BCG vaccination

scientific article

The role of flow cytometry in the interferon-gamma-based diagnosis of active tuberculosis and its coinfection with HIV-1--A technically oriented review

scientific article published on January 2008

A new perspective of the structural complexity of HCMV-specific T-cell responses

scientific article

Expansions of Cytotoxic CD4+CD28- T Cells Drive Excess Cardiovascular Mortality in Rheumatoid Arthritis and Other Chronic Inflammatory Conditions and Are Triggered by CMV Infection

scientific article published on 02 March 2017

Cytotoxic polyfunctionality maturation of cytomegalovirus-pp65-specific CD4 + and CD8 + T-cell responses in older adults positively correlates with response size

scientific article

Subclinical activation of latent cytomegalovirus (CMV) infection and anti-CMV immune response in patients with atopic dermatitis.

scientific article published in May 2003

Measurement of antigen specific immune responses: 2006 update

scientific article published on March 2007

Flow cytometric enumeration of antigen-specific T lymphocytes.

scientific article published in March 2004

Selection of CMV-specific CD8+ and CD4+ T cells by mini-EBV-transformed B cell lines

scientific article published in July 2005

CMV-Specific T-cell Responses at Older Ages: Broad Responses With a Large Central Memory Component May Be Key to Long-term Survival

scientific article published on 12 February 2017

List of works by Florian Kern

Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects

Protection from cytomegalovirus after transplantation is correlated with immediate early 1-specific CD8 T cells

T-cell epitope mapping by flow cytometry

Diagnosis of childhood tuberculosis and host RNA expression in Africa

Detection of tuberculosis in HIV-infected and -uninfected African adults using whole blood RNA expression signatures: a case-control study

Cytomegalovirus (CMV) phosphoprotein 65 makes a large contribution to shaping the T cell repertoire in CMV-exposed individuals

Target structures of the CD8(+)-T-cell response to human cytomegalovirus: the 72-kilodalton major immediate-early protein revisited.

Putative immunodominant human immunodeficiency virus-specific CD8(+) T-cell responses cannot be predicted by major histocompatibility complex class I haplotype

Standardizing Flow Cytometry Immunophenotyping Analysis from the Human ImmunoPhenotyping Consortium

Distribution of human CMV-specific memory T cells among the CD8pos. subsets defined by CD57, CD27, and CD45 isoforms

CMV and Immunosenescence: from basics to clinics

Polyfunctional T cells accumulate in large human cytomegalovirus-specific T cell responses

Cytomegalovirus infection induces the accumulation of short-lived, multifunctional CD4+CD45RA+CD27+ T cells: the potential involvement of interleukin-7 in this process

Loss of receptor on tuberculin-reactive T-cells marks active pulmonary tuberculosis

Mechanisms of human cytomegalovirus (HCMV) (re)activation and its impact on organ transplant patients.

Measuring Ag-specific immune responses: understanding immunopathogenesis and improving diagnostics in infectious disease, autoimmunity and cancer

Mapping T cell epitopes by flow cytometry

Circulating Plasma microRNAs can differentiate Human Sepsis and Systemic Inflammatory Response Syndrome (SIRS).

SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19

Age-associated increase of low-avidity cytomegalovirus-specific CD8+ T cells that re-express CD45RA

Hyperprocalcitonemia in Patients with Noninfectious SIRS and Pulmonary Dysfunction Associated with Cardiopulmonary Bypass

Immunosenescence and Cytomegalovirus: where do we stand after a decade?

High levels of CMV-IE-1-specific memory T cells are associated with less alloimmunity and improved renal allograft function

Random screening of proteins for HLA-A*0201-binding nine-amino acid peptides is not sufficient for identifying CD8 T cell epitopes recognized in the context of HLA-A*0201.

Analysis of antigen-specific T-cell responses with synthetic peptides--what kind of peptide for which purpose?

The enigma of CD57+CD28- T cell expansion--anergy or activation?

CMV-specific central memory T cells reside in bone marrow

How flow cytometry is changing the study of TB immunology and clinical diagnosis

Report from the second cytomegalovirus and immunosenescence workshop

Confirmation of Mycobacterium tuberculosis infection by flow cytometry after ex vivo incubation of peripheral blood T cells with an ESAT-6-derived peptide pool

A novel cytomegalovirus-induced regulatory-type T-cell subset increases in size during older life and links virus-specific immunity to vascular pathology

Secondary heterologous dengue infection risk: Disequilibrium between immune regulation and inflammation?

CD45RA(bright)/CD11a(bright) CD8+ T cells: effector T cells

Cell-mediated immunity to human CMV infection: a brief overview

Delayed-type hypersensitivity-like mechanisms dominate late acute rejection episodes in renal allograft recipients

Massive elevation of procalcitonin plasma levels in the absence of infection in kidney transplant patients treated with pan-T-cell antibodies

Enumeration of antigen-specific CD8+ T lymphocytes by single-platform, HLA tetramer-based flow cytometry: a European multicenter evaluation

HLA type-independent generation of antigen-specific T cells for adoptive immunotherapy

NS1 specific CD8+ T-cells with effector function and TRBV11 dominance in a patient with parvovirus B19 associated inflammatory cardiomyopathy

Detection of antigen-specific T cells by cytokine flow cytometry: the use of whole blood may underestimate frequencies

Tuberculin-specific T cells are reduced in active pulmonary tuberculosis compared to LTBI or status post BCG vaccination

The role of flow cytometry in the interferon-gamma-based diagnosis of active tuberculosis and its coinfection with HIV-1--A technically oriented review

A new perspective of the structural complexity of HCMV-specific T-cell responses

Expansions of Cytotoxic CD4+CD28- T Cells Drive Excess Cardiovascular Mortality in Rheumatoid Arthritis and Other Chronic Inflammatory Conditions and Are Triggered by CMV Infection

Cytotoxic polyfunctionality maturation of cytomegalovirus-pp65-specific CD4 + and CD8 + T-cell responses in older adults positively correlates with response size

Subclinical activation of latent cytomegalovirus (CMV) infection and anti-CMV immune response in patients with atopic dermatitis.

Measurement of antigen specific immune responses: 2006 update

Flow cytometric enumeration of antigen-specific T lymphocytes.

Selection of CMV-specific CD8+ and CD4+ T cells by mini-EBV-transformed B cell lines

CMV-Specific T-cell Responses at Older Ages: Broad Responses With a Large Central Memory Component May Be Key to Long-term Survival

Random screening of proteins for HLA-A0201-binding nine-amino acid peptides is not sufficient for identifying CD8 T cell epitopes recognized in the context of HLA-A0201.