List of works - Florian Kern

A clinical comparison of two commercially available pediatric hemoconcentrators.

scientific article published in March 2004

A new perspective of the structural complexity of HCMV-specific T-cell responses

scientific article

A novel cytomegalovirus-induced regulatory-type T-cell subset increases in size during older life and links virus-specific immunity to vascular pathology

scientific article

ATP stimulates Ca2+ mobilization by a nucleotide receptor in glomerular endothelial cells

scientific article published in February 1994

Age-associated increase of low-avidity cytomegalovirus-specific CD8+ T cells that re-express CD45RA

scientific article published on May 2013

Ammoniated mercury ointment as a cause of peripheral neuropathy.

scientific article

Amyloid-specific T-cells differentiate Alzheimer's disease from Lewy body dementia

scientific article published on 11 February 2012

Analysis of antigen-specific T-cell responses with synthetic peptides--what kind of peptide for which purpose?

scientific article

Anti-CD4 monoclonal antibody therapy of late acute rejection in renal allograft recipients--CD4+ T cells play an essential role in the rejection process

scientific article published on 01 February 1995

Association between CMV-related graft injury and circulating cytokine-producing CD8+ memory cells.

scientific article published in February 1995

Binase does not induce polyclonal T-cell response

scientific article published on 01 March 2006

Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects

scientific article

CD3+/LFA-1 "bright" T cells represent memory-type effector cells, which, during immune activation in kidney graft recipients, are marked by increased cytokine mRNA levels.

scientific article published in February 1995

CD45RA(bright)/CD11a(bright) CD8+ T cells: effector T cells

scientific article published in December 1998

CMV and Immunosenescence: from basics to clinics

scientific article published on 31 October 2012

CMV-Specific T-cell Responses at Older Ages: Broad Responses With a Large Central Memory Component May Be Key to Long-term Survival

scientific article published on 12 February 2017

CMV-specific central memory T cells reside in bone marrow

scientific article published in November 2007

Cell-mediated immunity to human CMV infection: a brief overview

scientific article

Characterisation of CD154+ T cells following ex vivo allergen stimulation illustrates distinct T cell responses to seasonal and perennial allergens in allergic and non-allergic individuals

scientific article

Characterisation of CD154+ T cells following ex vivo birch allergen stimulation defines a close relationship between T cell subsets in healthy volunteers

scientific article

Chlamydia pneumoniae-induced memory CD4+ T-cell activation in human peripheral blood correlates with distinct antibody response patterns

scientific article

Circulating Plasma microRNAs can differentiate Human Sepsis and Systemic Inflammatory Response Syndrome (SIRS).

scientific article published on 20 June 2016

Comparative study of the influence of proteasome inhibitor MG132 and ganciclovir on the cytomegalovirus-specific CD8(+) T-cell immune response

scientific article published on 23 November 2011

Comparison of proliferation and rapid cytokine induction assays for flow cytometric T-cell epitope mapping

scientific article published in March 2003

Confirmation of Mycobacterium tuberculosis infection by flow cytometry after ex vivo incubation of peripheral blood T cells with an ESAT-6-derived peptide pool

scientific article published in July 2004

Cross-sectional and longitudinal analysis of myelin-reactive T cells in patients with multiple sclerosis

article

Cyclosporin A and tacrolimus reduce T-cell polyfunctionality but not interferon-γ responses directed at cytomegalovirus

scientific article published in August 2012

Cytomegalovirus (CMV) phosphoprotein 65 makes a large contribution to shaping the T cell repertoire in CMV-exposed individuals

scientific article published on 31 May 2002

Cytomegalovirus as a Driver of Excess Cardiovascular Mortality in Rheumatoid Arthritis: A Red Herring or a Smoking Gun?

scientific article published in January 2017

Cytomegalovirus infection induces the accumulation of short-lived, multifunctional CD4+CD45RA+CD27+ T cells: the potential involvement of interleukin-7 in this process

scientific article published on 7 January 2011

Cytomegalovirus infection modulates the phenotype and functional profile of the T-cell immune response to mycobacterial antigens in older life

scientific article published on 25 December 2013

Cytotoxic polyfunctionality maturation of cytomegalovirus-pp65-specific CD4 + and CD8 + T-cell responses in older adults positively correlates with response size

scientific article

Delayed-type hypersensitivity-like mechanisms dominate late acute rejection episodes in renal allograft recipients

scientific article

Detection of antigen-specific T cells by cytokine flow cytometry: the use of whole blood may underestimate frequencies

scientific article published in December 2003

Detection of tuberculosis in HIV-infected and -uninfected African adults using whole blood RNA expression signatures: a case-control study

scientific article (publication date: October 2013)

Diagnosis of childhood tuberculosis and host RNA expression in Africa

scientific article published in May 2014

Discordant expression of LFA-1, VLA-4alpha, VLA-beta 1, CD45RO and CD28 on T-cell subsets: evidence for multiple subsets of 'memory' T cells

scientific article published in May 1994

Dissection of the CMV specific T-cell response is required for optimized cardiac transplant monitoring

scientific article published on 01 September 2008

Distribution of human CMV-specific memory T cells among the CD8pos. subsets defined by CD57, CD27, and CD45 isoforms

scientific article published in September 1999

Enumeration of antigen-specific CD8+ T lymphocytes by single-platform, HLA tetramer-based flow cytometry: a European multicenter evaluation

scientific article published on 01 November 2004

Evaluation of the frequency of virus-specific CD8+ T cells by cytokine flow cytometry.

scientific article published in January 2003

Expansions of Cytotoxic CD4+CD28- T Cells Drive Excess Cardiovascular Mortality in Rheumatoid Arthritis and Other Chronic Inflammatory Conditions and Are Triggered by CMV Infection

scientific article published on 02 March 2017

Flow cytometric enumeration of antigen-specific T lymphocytes.

scientific article published in March 2004

Functional Diversity of Cytomegalovirus-Specific T Cells Is Maintained in Older People and Significantly Associated With Protein Specificity and Response Size

scientific article published on 11 August 2016

Gender differences and age-specific associations between body mass index and other cardiovascular risk factors in CMV infected and uninfected people

scientific article

HLA type-independent generation of antigen-specific T cells for adoptive immunotherapy

scientific article published in July 2005

High levels of CMV-IE-1-specific memory T cells are associated with less alloimmunity and improved renal allograft function

scientific article published on 24 November 2008

How flow cytometry is changing the study of TB immunology and clinical diagnosis

scientific article

Hyperprocalcitonemia in Patients with Noninfectious SIRS and Pulmonary Dysfunction Associated with Cardiopulmonary Bypass ⬇️

scientific article published on July 1, 1998

Immunomodulatory therapies: challenges of individualized therapy strategies

scientific article published on 01 January 2006

Immunosenescence and Cytomegalovirus: where do we stand after a decade?

scientific article published on 7 September 2010

In-Depth Profiling of T-Cell Responsiveness to Commonly Recognized CMV Antigens in Older People Reveals Important Sex Differences

scientific article published on 13 August 2021

Interleukin-7 Unveils Pathogen-Specific T Cells by Enhancing Antigen-Recall Responses

scientific article published on 28 February 2018

Late acute rejection in long-term renal allograft recipients. Diagnostic and predictive value of circulating activated T cells

scientific article published on 01 July 1994

Loss of receptor on tuberculin-reactive T-cells marks active pulmonary tuberculosis

scientific article

Mapping T cell epitopes by flow cytometry

scientific article

Massive elevation of procalcitonin plasma levels in the absence of infection in kidney transplant patients treated with pan-T-cell antibodies

scientific article published on 01 June 2001

Measurement of antigen specific immune responses: 2006 update

scientific article published on March 2007

Measuring Ag-specific immune responses: understanding immunopathogenesis and improving diagnostics in infectious disease, autoimmunity and cancer

scientific article

Measuring antigen-specific immune responses, 2008 update

scientific article published on November 2008

Mechanisms of human cytomegalovirus (HCMV) (re)activation and its impact on organ transplant patients.

scientific article

NS1 specific CD8+ T-cells with effector function and TRBV11 dominance in a patient with parvovirus B19 associated inflammatory cardiomyopathy

scientific article

Peripheral T cell activation in long-term renal transplant patients: concordant upregulation of adhesion molecules and cytokine gene transcription

scientific article published on 01 November 1996

Persistent CMV infection correlates with disease activity and dominates the phenotype of peripheral CD8+ T cells in psoriasis

article published in 2011

Polyfunctional T cells accumulate in large human cytomegalovirus-specific T cell responses

scientific article published on 9 November 2011

Protection from cytomegalovirus after transplantation is correlated with immediate early 1-specific CD8 T cells

scientific article

Putative immunodominant human immunodeficiency virus-specific CD8(+) T-cell responses cannot be predicted by major histocompatibility complex class I haplotype

scientific article

Random screening of proteins for HLA-A0201-binding nine-amino acid peptides is not sufficient for identifying CD8 T cell epitopes recognized in the context of HLA-A0201.

scientific article published in June 2004

Recent developments in flow cytometry.

scientific article

Release of WBC-derived IL-1 receptor antagonist into supernatants of RBCs: influence of storage time and filtration

scientific article published in January 2001

Report from the second cytomegalovirus and immunosenescence workshop

scientific article published on 28 October 2011

SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19

scientific article published on 29 July 2020

Secondary heterologous dengue infection risk: Disequilibrium between immune regulation and inflammation?

scientific article published on 10 February 2010

Selection of CMV-specific CD8+ and CD4+ T cells by mini-EBV-transformed B cell lines

scientific article published in July 2005

Severity of Systemic Inflammatory Response Syndrome Affects the Blood Levels of Circulating Inflammatory-Relevant MicroRNAs

scientific article published in January 2017

Simultaneous Monitoring of Cytomegalovirus-Specific Antibody and T-cell levels in Seropositive Heart Transplant Recipients

Simultaneous characterization of phospho-proteins and cell cycle in activated T cell subsets

scientific article

Sorting and pooling strategy: a novel tool to map a virus proteome for CD8 T-cell epitopes

scientific article published in January 2007

Specific central memory T cells in the bone marrow of patients immunized against tyrosinase peptides

scientific article published in March 2006

Standardizing Flow Cytometry Immunophenotyping Analysis from the Human ImmunoPhenotyping Consortium

scientific article

Subclinical activation of latent cytomegalovirus (CMV) infection and anti-CMV immune response in patients with atopic dermatitis.

scientific article published in May 2003

T cell response to the cytomegalovirus major capsid protein (UL86) is dominated by helper cells with a large polyfunctional component and diverse epitope recognition.

scientific article published in May 2008

T-cell epitope mapping by flow cytometry ⬇️

scientific article published on August 1, 1998

Target structures of the CD8(+)-T-cell response to human cytomegalovirus: the 72-kilodalton major immediate-early protein revisited.

scientific article published on October 1999

The enigma of CD57+CD28- T cell expansion--anergy or activation?

scientific article published in April 1996

The phenotypic distribution and functional profile of tuberculin-specific CD4 T-cells characterizes different stages of TB infection.

scientific article published on 7 September 2012

The role of angiogenic growth factors in breast cancer progression.

scientific article published on June 1996

The role of flow cytometry in the interferon-gamma-based diagnosis of active tuberculosis and its coinfection with HIV-1--A technically oriented review

scientific article published on January 2008

Tuberculin-specific T cells are reduced in active pulmonary tuberculosis compared to LTBI or status post BCG vaccination

scientific article

Use of peptides and peptide libraries as T-cell stimulants in flow cytometric studies.

scientific article published in January 2004

WITHDRAWN: Gender differences and age-specific associations between Body Mass Index and other cardiovascular risk factors in CMV infected and uninfected people

retracted scientific article published on 22 September 2014

Xymedon decreases phosphatidylserine membrane expression induced by proapoptogenic deficit of serum growth factors in Jurkat T-cells

scientific article

[Aspiration of petroleum by a "fire-eater"]

scientific article published on 01 June 1995

List of works by Florian Kern

A clinical comparison of two commercially available pediatric hemoconcentrators.

A new perspective of the structural complexity of HCMV-specific T-cell responses

A novel cytomegalovirus-induced regulatory-type T-cell subset increases in size during older life and links virus-specific immunity to vascular pathology

ATP stimulates Ca2+ mobilization by a nucleotide receptor in glomerular endothelial cells

Age-associated increase of low-avidity cytomegalovirus-specific CD8+ T cells that re-express CD45RA

Ammoniated mercury ointment as a cause of peripheral neuropathy.

Amyloid-specific T-cells differentiate Alzheimer's disease from Lewy body dementia

Analysis of antigen-specific T-cell responses with synthetic peptides--what kind of peptide for which purpose?

Anti-CD4 monoclonal antibody therapy of late acute rejection in renal allograft recipients--CD4+ T cells play an essential role in the rejection process

Association between CMV-related graft injury and circulating cytokine-producing CD8+ memory cells.

Binase does not induce polyclonal T-cell response

Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects

CD3+/LFA-1 "bright" T cells represent memory-type effector cells, which, during immune activation in kidney graft recipients, are marked by increased cytokine mRNA levels.

CD45RA(bright)/CD11a(bright) CD8+ T cells: effector T cells

CMV and Immunosenescence: from basics to clinics

CMV-Specific T-cell Responses at Older Ages: Broad Responses With a Large Central Memory Component May Be Key to Long-term Survival

CMV-specific central memory T cells reside in bone marrow

Cell-mediated immunity to human CMV infection: a brief overview

Characterisation of CD154+ T cells following ex vivo allergen stimulation illustrates distinct T cell responses to seasonal and perennial allergens in allergic and non-allergic individuals

Characterisation of CD154+ T cells following ex vivo birch allergen stimulation defines a close relationship between T cell subsets in healthy volunteers

Chlamydia pneumoniae-induced memory CD4+ T-cell activation in human peripheral blood correlates with distinct antibody response patterns

Circulating Plasma microRNAs can differentiate Human Sepsis and Systemic Inflammatory Response Syndrome (SIRS).

Comparative study of the influence of proteasome inhibitor MG132 and ganciclovir on the cytomegalovirus-specific CD8(+) T-cell immune response

Comparison of proliferation and rapid cytokine induction assays for flow cytometric T-cell epitope mapping

Confirmation of Mycobacterium tuberculosis infection by flow cytometry after ex vivo incubation of peripheral blood T cells with an ESAT-6-derived peptide pool

Cross-sectional and longitudinal analysis of myelin-reactive T cells in patients with multiple sclerosis

Cyclosporin A and tacrolimus reduce T-cell polyfunctionality but not interferon-γ responses directed at cytomegalovirus

Cytomegalovirus (CMV) phosphoprotein 65 makes a large contribution to shaping the T cell repertoire in CMV-exposed individuals

Cytomegalovirus as a Driver of Excess Cardiovascular Mortality in Rheumatoid Arthritis: A Red Herring or a Smoking Gun?

Cytomegalovirus infection induces the accumulation of short-lived, multifunctional CD4+CD45RA+CD27+ T cells: the potential involvement of interleukin-7 in this process

Cytomegalovirus infection modulates the phenotype and functional profile of the T-cell immune response to mycobacterial antigens in older life

Cytotoxic polyfunctionality maturation of cytomegalovirus-pp65-specific CD4 + and CD8 + T-cell responses in older adults positively correlates with response size

Delayed-type hypersensitivity-like mechanisms dominate late acute rejection episodes in renal allograft recipients

Detection of antigen-specific T cells by cytokine flow cytometry: the use of whole blood may underestimate frequencies

Detection of tuberculosis in HIV-infected and -uninfected African adults using whole blood RNA expression signatures: a case-control study

Diagnosis of childhood tuberculosis and host RNA expression in Africa

Discordant expression of LFA-1, VLA-4alpha, VLA-beta 1, CD45RO and CD28 on T-cell subsets: evidence for multiple subsets of 'memory' T cells

Dissection of the CMV specific T-cell response is required for optimized cardiac transplant monitoring

Distribution of human CMV-specific memory T cells among the CD8pos. subsets defined by CD57, CD27, and CD45 isoforms

Enumeration of antigen-specific CD8+ T lymphocytes by single-platform, HLA tetramer-based flow cytometry: a European multicenter evaluation

Evaluation of the frequency of virus-specific CD8+ T cells by cytokine flow cytometry.

Expansions of Cytotoxic CD4+CD28- T Cells Drive Excess Cardiovascular Mortality in Rheumatoid Arthritis and Other Chronic Inflammatory Conditions and Are Triggered by CMV Infection

Flow cytometric enumeration of antigen-specific T lymphocytes.

Functional Diversity of Cytomegalovirus-Specific T Cells Is Maintained in Older People and Significantly Associated With Protein Specificity and Response Size

Gender differences and age-specific associations between body mass index and other cardiovascular risk factors in CMV infected and uninfected people

HLA type-independent generation of antigen-specific T cells for adoptive immunotherapy

High levels of CMV-IE-1-specific memory T cells are associated with less alloimmunity and improved renal allograft function

How flow cytometry is changing the study of TB immunology and clinical diagnosis

Hyperprocalcitonemia in Patients with Noninfectious SIRS and Pulmonary Dysfunction Associated with Cardiopulmonary Bypass ⬇️

Immunomodulatory therapies: challenges of individualized therapy strategies

Immunosenescence and Cytomegalovirus: where do we stand after a decade?

In-Depth Profiling of T-Cell Responsiveness to Commonly Recognized CMV Antigens in Older People Reveals Important Sex Differences

Interleukin-7 Unveils Pathogen-Specific T Cells by Enhancing Antigen-Recall Responses

Late acute rejection in long-term renal allograft recipients. Diagnostic and predictive value of circulating activated T cells

Loss of receptor on tuberculin-reactive T-cells marks active pulmonary tuberculosis

Mapping T cell epitopes by flow cytometry

Massive elevation of procalcitonin plasma levels in the absence of infection in kidney transplant patients treated with pan-T-cell antibodies

Measurement of antigen specific immune responses: 2006 update

Measuring Ag-specific immune responses: understanding immunopathogenesis and improving diagnostics in infectious disease, autoimmunity and cancer

Measuring antigen-specific immune responses, 2008 update

Mechanisms of human cytomegalovirus (HCMV) (re)activation and its impact on organ transplant patients.

NS1 specific CD8+ T-cells with effector function and TRBV11 dominance in a patient with parvovirus B19 associated inflammatory cardiomyopathy

Peripheral T cell activation in long-term renal transplant patients: concordant upregulation of adhesion molecules and cytokine gene transcription

Persistent CMV infection correlates with disease activity and dominates the phenotype of peripheral CD8+ T cells in psoriasis

Polyfunctional T cells accumulate in large human cytomegalovirus-specific T cell responses

Protection from cytomegalovirus after transplantation is correlated with immediate early 1-specific CD8 T cells

Putative immunodominant human immunodeficiency virus-specific CD8(+) T-cell responses cannot be predicted by major histocompatibility complex class I haplotype

Random screening of proteins for HLA-A*0201-binding nine-amino acid peptides is not sufficient for identifying CD8 T cell epitopes recognized in the context of HLA-A*0201.

Recent developments in flow cytometry.

Release of WBC-derived IL-1 receptor antagonist into supernatants of RBCs: influence of storage time and filtration

Report from the second cytomegalovirus and immunosenescence workshop

SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19

Secondary heterologous dengue infection risk: Disequilibrium between immune regulation and inflammation?

Selection of CMV-specific CD8+ and CD4+ T cells by mini-EBV-transformed B cell lines

Severity of Systemic Inflammatory Response Syndrome Affects the Blood Levels of Circulating Inflammatory-Relevant MicroRNAs

Simultaneous Monitoring of Cytomegalovirus-Specific Antibody and T-cell levels in Seropositive Heart Transplant Recipients

Simultaneous characterization of phospho-proteins and cell cycle in activated T cell subsets

Sorting and pooling strategy: a novel tool to map a virus proteome for CD8 T-cell epitopes

Specific central memory T cells in the bone marrow of patients immunized against tyrosinase peptides

Random screening of proteins for HLA-A0201-binding nine-amino acid peptides is not sufficient for identifying CD8 T cell epitopes recognized in the context of HLA-A0201.