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List of works by Kelly M McNagny

A novel ENU-generated truncation mutation lacking the spectrin-binding and C-terminal regulatory domains of Ank1 models severe hemolytic hereditary spherocytosis

scientific article

Bone marrow-derived mast cells accumulate in the central nervous system during inflammation but are dispensable for experimental autoimmune encephalomyelitis pathogenesis

scientific article published in May 2009

CD34 is a key regulator of hematopoietic stem cell trafficking to bone marrow and mast cell progenitor trafficking in the periphery

scientific article published on August 2009

CD34 is required for dendritic cell trafficking and pathology in murine hypersensitivity pneumonitis

scientific article

CD34 is required for infiltration of eosinophils into the colon and pathology associated with DSS-induced ulcerative colitis.

scientific article published on 9 August 2010

CD34 mediates intestinal inflammation in Salmonella-infected mice

scientific article published in November 2010

CD34 promotes satellite cell motility and entry into proliferation to facilitate efficient skeletal muscle regeneration.

scientific article

Cytopenia induction by 5-fluorouracil identifies thrombopoietic mutants in sensitized ENU mutagenesis screens ⬇️

scientific article

Early life antibiotic-driven changes in microbiota enhance susceptibility to allergic asthma

scientific article

G9a regulates group 2 innate lymphoid cell development by repressing the group 3 innate lymphoid cell program

scientific article published on 13 June 2016

Genes, the environment and personalized medicine: We need to harness both environmental and genetic data to maximize personal and population health

scientific article

Granzyme B deficiency exacerbates lung inflammation in mice after acute lung injury

scientific article published in September 2013

Group 2 innate lymphoid cells are critical for the initiation of adaptive T helper 2 cell-mediated allergic lung inflammation

scientific article published on 6 March 2014

Group 2 innate lymphoid cells facilitate sensitization to local, but not systemic, TH2-inducing allergen exposures

scientific article

Hedgehog signaling in the airway epithelium of patients with chronic obstructive pulmonary disease

scientific article published on 04 March 2019

IL-22 Preserves Gut Epithelial Integrity and Promotes Disease Remission during Chronic Salmonella Infection

scientific article published on 07 January 2019

IQCELL: A platform for predicting the effect of gene perturbations on developmental trajectories using single-cell RNA-seq data

scientific article published on 25 February 2022

Impairing eukaryotic elongation factor 2 kinase activity decreases atherosclerotic plaque formation.

scientific article published on 28 September 2014

Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool

scientific article published on 31 July 2011

Inhaled Corticosteroids Selectively Alter the Microbiome and Host Transcriptome in the Small Airways of Patients with Chronic Obstructive Pulmonary Disease

scientific article published on 11 May 2022

Interleukin-11 reduces TLR4-induced colitis in TLR2-deficient mice and restores intestinal STAT3 signaling.

scientific article published on 25 June 2010

Loss of CD34 leads to exacerbated autoimmune arthritis through increased vascular permeability

scientific article published on 28 December 2009

Mast cells in tumor growth: angiogenesis, tissue remodelling and immune-modulation

scientific article published on 21 February 2009

Mast cells promote small bowel cancer in a tumor stage-specific and cytokine-dependent manner

scientific article published on 2 February 2018

Methyltransferase G9A regulates T cell differentiation during murine intestinal inflammation

scientific article published on 25 March 2014

Mouse models to evaluate the function of genes associated with allergic airway disease ⬇️

scientific article published on October 1, 2012

Mutant mice and animal models of airway allergic disease

scientific article published in January 2014

Myeloid cell-specific expression of Ship1 regulates IL-12 production and immunity to helminth infection

article

PODO447: a novel antibody to a tumor-restricted epitope on the cancer antigen podocalyxin

scientific article published on 01 November 2020

Perinatal Immunization With Vaccine-Grade Listeria monocytogenes Provides Protection Against Murine Th2 Airway Inflammation

scientific article

Podocalyxin is required for maintaining blood-brain barrier function during acute inflammation

scientific article published on 20 February 2019

Podocalyxin selectively marks erythroid-committed progenitors during anemic stress but is dispensable for efficient recovery.

scientific article published on 11 November 2008

Proceedings of the Canadian society of allergy and clinical immunology annual scientific meeting 2015

scientific article (publication date: May 2016)

Retinoic-acid-receptor-related orphan nuclear receptor alpha is required for natural helper cell development and allergic inflammation.

scientific article

SHIP represses Th2 skewing by inhibiting IL-4 production from basophils

scientific article published on 3 December 2010

The Transcription Factor RORα Preserves ILC3 Lineage Identity and Function during Chronic Intestinal Infection

scientific article published on 01 November 2019

The anti-adhesive mucin podocalyxin may help initiate the transperitoneal metastasis of high grade serous ovarian carcinoma.

scientific article published on 20 January 2012

The changing landscape of human-animal chimera research: A Canadian regulatory perspective

scientific article published on 14 October 2009

The first identified heterozygous nonsense mutations in podocalyxin offer new perspectives on the biology of podocytopathies

scientific article published on 08 February 2019

The metalloprotease-disintegrin ADAM8 is essential for the development of experimental asthma

scientific journal article

iPS cells: mapping the policy issues

scientific article published on December 2009

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