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List of works by Dirk Brenner

2-Methoxyestradiol inhibits experimental autoimmune encephalomyelitis through suppression of immune cell activation ⬇️

scientific article published on December 3, 2012

Activation or suppression of NFkappaB by HPK1 determines sensitivity to activation-induced cell death

scientific article published on 8 December 2005

Antigen receptor-mediated depletion of FOXP3 in induced regulatory T-lymphocytes via PTPN2 and FOXO1.

scientific article

Autophagy-independent functions of UVRAG are essential for peripheral naive T-cell homeostasis

scientific article

B-Cell Metabolic Remodeling and Cancer

scientific article published in February 2018

BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival

scientific article published on 15 July 2013

Caspase-cleaved HPK1 induces CD95L-independent activation-induced cell death in T and B lymphocytes

scientific article published on 21 August 2007

Cellular senescence or EGFR signaling induces Interleukin 6 (IL-6) receptor expression controlled by mammalian target of rapamycin (mTOR).

scientific article published on 18 September 2013

Choline acetyltransferase-expressing T cells are required to control chronic viral infection

scientific article published on 01 February 2019

Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation

scientific article

Deprivation of dietary fiber in specific-pathogen-free mice promotes susceptibility to the intestinal mucosal pathogen <i>Citrobacter rodentium</i>

scientific article published on 01 January 2021

Energy-sensitive regulation of Na+/K+-ATPase by Janus kinase 2.

scientific article published on 4 December 2013

Enterohaemorrhagic, but not enteropathogenic, Escherichia coli infection of epithelial cells disrupts signalling responses to tumour necrosis factor-alpha

scientific article

Fragile X mental retardation protein protects against tumour necrosis factor-mediated cell death and liver injury

scientific article published on 13 August 2019

Glutathione Primes T Cell Metabolism for Inflammation

scientific article published on 01 June 2017

Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression

Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression

scientific article published on 22 January 2015

Glutathione-dependent redox balance characterizes the distinct metabolic properties of follicular and marginal zone B cells

scientific article published on 04 April 2022

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

scientific article published on 01 October 2019

HDAC inhibitors trigger apoptosis in HPV-positive cells by inducing the E2F-p73 pathway.

scientific article

HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1.

scientific article

Histone deacetylase inhibitor-induced sensitization to TNFalpha/TRAIL-mediated apoptosis in cervical carcinoma cells is dependent on HPV oncogene expression.

scientific article

IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics

scientific article published on August 2012

IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis

scientific article published on 10 December 2012

Idh1 protects murine hepatocytes from endotoxin-induced oxidative stress by regulating the intracellular NADP(+)/NADPH ratio.

scientific article

In vitro generated human memory-like T cells are CD95 type II cells and resistant towards CD95-mediated apoptosis

scientific article published in November 2006

K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression.

scientific article published on 13 January 2017

Lack of T-cell receptor-induced signaling is crucial for CD95 ligand up-regulation and protects cutaneous T-cell lymphoma cells from activation-induced cell death

scientific article

Lymphocyte-derived ACh regulates local innate but not adaptive immunity

scientific article published on 7 January 2013

MALT1 is an intrinsic regulator of regulatory T cells.

scientific article

Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis

scientific article published on 16 May 2022

Mitochondrial cell death effectors.

scientific article published on 12 October 2009

Phosphorylation of CARMA1 by HPK1 is critical for NF-kappaB activation in T cells

scholarly article

Protection from EAE in DOCK8 mutant mice occurs despite increased Th17 cell frequencies in the periphery

scientific article published on 20 February 2019

RAIDD Mediates TLR3 and IRF7 Driven Type I Interferon Production.

scientific article published on 8 September 2016

Reactive Oxygen Species: Involvement in T Cell Signaling and Metabolism

scientific article published on 13 February 2018

Reactive oxygen species delay control of lymphocytic choriomeningitis virus ⬇️

scientific article published on January 18, 2013

Reduced type I interferon production by dendritic cells and weakened antiviral immunity in patients with Wiskott-Aldrich syndrome protein deficiency

scientific article

Regulation of tumour necrosis factor signalling: live or let die

scientific article

Regulatory t cell metabolism at the intersection between autoimmune diseases and cancer

scientific article published on 16 October 2020

Survival of the fittest: Cancer challenges T cell metabolism.

scientific article published on 23 October 2017

Sustained JNK signaling by proteolytically processed HPK1 mediates IL-3 independent survival during monocytic differentiation.

scientific article

TNF and ROS Crosstalk in Inflammation

scientific article

The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis.

scientific article published on 2 January 2012

The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells

scientific article published on November 2012

The TNF Family of Ligands and Receptors: Communication Modules in the Immune System and Beyond

scientific article published on 01 January 2019

The c-FLIP-NH2 terminus (p22-FLIP) induces NF-kappaB activation.

scientific article published on 8 May 2006

Toso regulates differentiation and activation of inflammatory dendritic cells during persistence-prone virus infection

scientific article published on 26 September 2014

Tumor Necrosis Factor-Mediated Survival of CD169+ Cells Promotes Immune Activation during Vesicular Stomatitis Virus Infection

scientific article published on 15 November 2017

c-FLIPR, a new regulator of death receptor-induced apoptosis.

scientific article

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