List of works - Emmanuel A. Asante

A naturally occurring variant of the human prion protein completely prevents prion disease.

scientific article

Absence of spontaneous disease and comparative prion susceptibility of transgenic mice expressing mutant human prion proteins

scientific article

Atypical scrapie prions from sheep and lack of disease in transgenic mice overexpressing human prion protein.

scientific article

BSE prions propagate as either variant CJD-like or sporadic CJD-like prion strains in transgenic mice expressing human prion protein

scientific article published on December 2002

Chronic wasting disease prions are not transmissible to transgenic mice overexpressing human prion protein

scientific article

Dissociation of pathological and molecular phenotype of variant Creutzfeldt-Jakob disease in transgenic human prion protein 129 heterozygous mice

scholarly article

Effect of fixation on brain and lymphoreticular vCJD prions and bioassay of key positive specimens from a retrospective vCJD prevalence study

scientific article published on 10 December 2010

Expression of human full-length and minidystrophin in transgenic mdx mice: implications for gene therapy of Duchenne muscular dystrophy ⬇️

scientific article published on August 1, 1995

Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology

scientific article

Inherited prion disease A117V is not simply a proteinopathy but produces prions transmissible to transgenic mice expressing homologous prion protein.

scientific article

Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites

scientific article

Kuru prions and sporadic Creutzfeldt-Jakob disease prions have equivalent transmission properties in transgenic and wild-type mice

scientific article

Overexpression of the Hspa13 (Stch) gene reduces prion disease incubation time in mice

scientific article

Pathogenic human prion protein rescues PrP null phenotype in transgenic mice.

scientific article

Phenotypic heterogeneity in inherited prion disease (P102L) is associated with differential propagation of protease-resistant wild-type and mutant prion protein.

scientific article published on 5 April 2006

Prion infectivity in variant Creutzfeldt-Jakob disease rectum.

scientific article published on 8 June 2006

Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice

scientific article published in March 2012

Protective Effect of Val129-PrP against Bovine Spongiform Encephalopathy but not Variant Creutzfeldt-Jakob Disease.

scientific article published on September 2017

Review. The origin of the prion agent of kuru: molecular and biological strain typing.

scientific article published on November 2008

Review: contribution of transgenic models to understanding human prion disease.

scientific article

Rskα-actin/hIGF-1 transgenic mice with increased IGF-I in skeletal muscle and blood: Impact on regeneration, denervation and muscular dystrophy

scientific article published in June 2006

Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS

scientific article published on 09 June 2020

Threshold for epileptiform activity is elevated in prion knockout mice

scientific article published on 28 January 2011

Tissue specific expression of an alpha-skeletal actin-lacZ fusion gene during development in transgenic mice

scientific article published in January 1994

Transgenic studies of the influence of the PrP structure on TSE diseases.

scientific article

Transmission Properties of Human PrP 102L Prions Challenge the Relevance of Mouse Models of GSS.

scientific article published on 2 July 2015

Unaltered susceptibility to BSE in transgenic mice expressing human prion protein.

scientific article

List of works by Emmanuel A. Asante

A naturally occurring variant of the human prion protein completely prevents prion disease.

Absence of spontaneous disease and comparative prion susceptibility of transgenic mice expressing mutant human prion proteins

Atypical scrapie prions from sheep and lack of disease in transgenic mice overexpressing human prion protein.

BSE prions propagate as either variant CJD-like or sporadic CJD-like prion strains in transgenic mice expressing human prion protein

Chronic wasting disease prions are not transmissible to transgenic mice overexpressing human prion protein

Dissociation of pathological and molecular phenotype of variant Creutzfeldt-Jakob disease in transgenic human prion protein 129 heterozygous mice

Effect of fixation on brain and lymphoreticular vCJD prions and bioassay of key positive specimens from a retrospective vCJD prevalence study

Expression of human full-length and minidystrophin in transgenic mdx mice: implications for gene therapy of Duchenne muscular dystrophy ⬇️

Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology

Inherited prion disease A117V is not simply a proteinopathy but produces prions transmissible to transgenic mice expressing homologous prion protein.

Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites

Kuru prions and sporadic Creutzfeldt-Jakob disease prions have equivalent transmission properties in transgenic and wild-type mice

Overexpression of the Hspa13 (Stch) gene reduces prion disease incubation time in mice

Pathogenic human prion protein rescues PrP null phenotype in transgenic mice.

Phenotypic heterogeneity in inherited prion disease (P102L) is associated with differential propagation of protease-resistant wild-type and mutant prion protein.

Prion infectivity in variant Creutzfeldt-Jakob disease rectum.

Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice

Protective Effect of Val129-PrP against Bovine Spongiform Encephalopathy but not Variant Creutzfeldt-Jakob Disease.

Review. The origin of the prion agent of kuru: molecular and biological strain typing.

Review: contribution of transgenic models to understanding human prion disease.

Rskα-actin/hIGF-1 transgenic mice with increased IGF-I in skeletal muscle and blood: Impact on regeneration, denervation and muscular dystrophy

Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS

Threshold for epileptiform activity is elevated in prion knockout mice

Tissue specific expression of an alpha-skeletal actin-lacZ fusion gene during development in transgenic mice

Transgenic studies of the influence of the PrP structure on TSE diseases.

Transmission Properties of Human PrP 102L Prions Challenge the Relevance of Mouse Models of GSS.

Unaltered susceptibility to BSE in transgenic mice expressing human prion protein.