List of works - David Mottershead

A covalently dimerized recombinant human bone morphogenetic protein-15 variant identifies bone morphogenetic protein receptor type 1B as a key cell surface receptor on ovarian granulosa cells

scientific article published on 31 January 2012

Aberrant GDF9 expression and activation are associated with common human ovarian disorders.

scientific article

Adenoviral gene transfer allows Smad-responsive gene promoter analyses and delineation of type I receptor usage of transforming growth factor-beta family ligands in cultured human granulosa luteal cells.

scientific article published on 13 October 2004

Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor channels lacking the N-terminal domain

scientific article (publication date: 20 December 2002)

Amphiregulin co-operates with bone morphogenetic protein 15 to increase bovine oocyte developmental competence: effects on gap junction-mediated metabolite supply.

scientific article published on 19 February 2014

Baculoviral display of functional scFv and synthetic IgG-binding domains.

scientific article published on August 2000

Baculoviral display of the green fluorescent protein and rubella virus envelope proteins.

scientific article

Bone morphogenetic protein 15 and growth differentiation factor 9 co-operate to regulate granulosa cell function in ruminants

scientific article published in April 2005

Bone morphogenetic protein 15 and growth differentiation factor 9 co-operate to regulate granulosa cell function.

scientific article published in April 2005

Bone morphogenetic protein 15 in the pro-mature complex form enhances bovine oocyte developmental competence

scientific article

Cumulin, an Oocyte-secreted Heterodimer of the Transforming Growth Factor-β Family, Is a Potent Activator of Granulosa Cells and Improves Oocyte Quality

scientific article

Determinants of antagonist binding at the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor subunit, GluR-D. Role of the conserved arginine 507 and glutamate 727 residues

scientific article published in December 2002

Direct binding of the Mtv7 superantigen (Mls-1) to soluble MHC class II molecules.

scientific article

Effects of differing oocyte-secreted factors during mouse in vitro maturation on subsequent embryo and fetal development

scientific article published on 11 January 2014

Growth differentiation factor 9 signaling requires ERK1/2 activity in mouse granulosa and cumulus cells.

scientific article published on 24 August 2010

Growth differentiation factor 9:bone morphogenetic protein 15 (GDF9:BMP15) synergism and protein heterodimerization.

scientific article published on 6 May 2013

Immunoneutralization of growth differentiation factor 9 reveals it partially accounts for mouse oocyte mitogenic activity.

scientific article

Inhibition of oocyte growth factors in vivo modulates ovarian folliculogenesis in neonatal and immature mice.

scientific article published on 10 December 2009

Metabolic differences in bovine cumulus-oocyte complexes matured in vitro in the presence or absence of follicle-stimulating hormone and bone morphogenetic protein 15.

scientific article published on 11 October 2012

Mimicking rubella virus particles by using recombinant envelope glycoproteins and liposomes.

scientific article published on October 1999

Modifications of human growth differentiation factor 9 to improve the generation of embryos from low competence oocytes.

scientific article

Molecular basis of oocyte-paracrine signalling that promotes granulosa cell proliferation

scientific article published on 22 August 2006

Mouse GDF9 decreases KITL gene expression in human granulosa cells

scientific article

Promotion of EGF receptor signaling improves the quality of low developmental competence oocytes.

scientific article

Redox and anti-oxidant state within cattle oocytes following in vitro maturation with bone morphogenetic protein 15 and follicle stimulating hormone

scientific article

Seminal fluid factors regulate activin A and follistatin synthesis in female cervical epithelial cells.

scientific article published on 25 September 2015

Signalling pathways involved in the synergistic effects of human growth differentiation factor 9 and bone morphogenetic protein 15.

scientific article

Smad signalling in the ovary

scientific article

Specific binding of baculoviruses displaying gp64 fusion proteins to mammalian cells.

scientific article published in June 2001

TGF-β mediates proinflammatory seminal fluid signaling in human cervical epithelial cells.

scientific article published on 15 June 2012

The bioactivity of human bone morphogenetic protein-15 is sensitive to C-terminal modification: characterization of the purified untagged processed mature region.

scientific article published on 16 October 2010

List of works by David Mottershead

A covalently dimerized recombinant human bone morphogenetic protein-15 variant identifies bone morphogenetic protein receptor type 1B as a key cell surface receptor on ovarian granulosa cells

Aberrant GDF9 expression and activation are associated with common human ovarian disorders.

Adenoviral gene transfer allows Smad-responsive gene promoter analyses and delineation of type I receptor usage of transforming growth factor-beta family ligands in cultured human granulosa luteal cells.

Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor channels lacking the N-terminal domain

Amphiregulin co-operates with bone morphogenetic protein 15 to increase bovine oocyte developmental competence: effects on gap junction-mediated metabolite supply.

Baculoviral display of functional scFv and synthetic IgG-binding domains.

Baculoviral display of the green fluorescent protein and rubella virus envelope proteins.

Bone morphogenetic protein 15 and growth differentiation factor 9 co-operate to regulate granulosa cell function in ruminants

Bone morphogenetic protein 15 and growth differentiation factor 9 co-operate to regulate granulosa cell function.

Bone morphogenetic protein 15 in the pro-mature complex form enhances bovine oocyte developmental competence

Cumulin, an Oocyte-secreted Heterodimer of the Transforming Growth Factor-β Family, Is a Potent Activator of Granulosa Cells and Improves Oocyte Quality

Determinants of antagonist binding at the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor subunit, GluR-D. Role of the conserved arginine 507 and glutamate 727 residues

Direct binding of the Mtv7 superantigen (Mls-1) to soluble MHC class II molecules.

Effects of differing oocyte-secreted factors during mouse in vitro maturation on subsequent embryo and fetal development

Growth differentiation factor 9 signaling requires ERK1/2 activity in mouse granulosa and cumulus cells.

Growth differentiation factor 9:bone morphogenetic protein 15 (GDF9:BMP15) synergism and protein heterodimerization.

Immunoneutralization of growth differentiation factor 9 reveals it partially accounts for mouse oocyte mitogenic activity.

Inhibition of oocyte growth factors in vivo modulates ovarian folliculogenesis in neonatal and immature mice.

Metabolic differences in bovine cumulus-oocyte complexes matured in vitro in the presence or absence of follicle-stimulating hormone and bone morphogenetic protein 15.

Mimicking rubella virus particles by using recombinant envelope glycoproteins and liposomes.

Modifications of human growth differentiation factor 9 to improve the generation of embryos from low competence oocytes.

Molecular basis of oocyte-paracrine signalling that promotes granulosa cell proliferation

Mouse GDF9 decreases KITL gene expression in human granulosa cells

Promotion of EGF receptor signaling improves the quality of low developmental competence oocytes.

Redox and anti-oxidant state within cattle oocytes following in vitro maturation with bone morphogenetic protein 15 and follicle stimulating hormone

Seminal fluid factors regulate activin A and follistatin synthesis in female cervical epithelial cells.

Signalling pathways involved in the synergistic effects of human growth differentiation factor 9 and bone morphogenetic protein 15.

Smad signalling in the ovary

Specific binding of baculoviruses displaying gp64 fusion proteins to mammalian cells.

TGF-β mediates proinflammatory seminal fluid signaling in human cervical epithelial cells.

The bioactivity of human bone morphogenetic protein-15 is sensitive to C-terminal modification: characterization of the purified untagged processed mature region.