List of works - Mårten Segelmark

A candidate gene approach to ANCA-associated vasculitis reveals links to the C3 and CTLA-4 genes but not to the IL1-Ra and Fcγ-RIIa genes.

scientific article

A myelopoiesis gene signature during remission in anti-neutrophil cytoplasm antibody-associated vasculitis does not predict relapses but seems to reflect ongoing prednisolone therapy.

scientific article

A population-based study showing better renal prognosis for proteinase 3 antineutrophil cytoplasmic antibody (ANCA)-associated nephritis versus myeloperoxidase ANCA-associated nephritis.

scientific article published in June 2014

ANCA antigens, proteinase 3 and myeloperoxidase, are not expressed in endothelial cells

scientific article published on 01 May 2000

Anti-GBM antibodies in Goodpasture syndrome; anatomy of an epitope

scientific article published on 01 April 1997

Anti-GBM disease with a mild relapsing course and low levels of anti-GBM autoantibodies

scientific article

Antigen and epitope specificity of anti-glomerular basement membrane antibodies in patients with goodpasture disease with or without anti-neutrophil cytoplasmic antibodies.

scientific article published on 28 February 2007

Association of cigarette smoking with organ damage in primary systemic vasculitis

scientific article published on 21 September 2010

Autoantibody response to BPI predict disease severity and outcome in cystic fibrosis

scientific article published on 12 December 2006

Autoimmune kidney diseases

scientific article

BPI-ANCA and long-term prognosis among 46 adult CF patients: a prospective 10-year follow-up study.

scientific article published on 30 December 2012

C3 and C4 allotypes in anti-neutrophil cytoplasmic autoantibody (ANCA)-positive vasculitis

scientific article published in May 1999

Circulating anti-glomerular basement membrane antibodies with predominance of subclass IgG4 and false-negative immunoassay test results in anti-glomerular basement membrane disease

scientific article published on 01 November 2013

Circulating cytokine profile in anti-neutrophilic cytoplasmatic autoantibody-associated vasculitis: prediction of outcome?

scientific article published on August 2004

Clinical evaluation of a capture ELISA for detection of proteinase-3 antineutrophil cytoplasmic antibody

scientific article published on 01 May 1998

Decreased neutrophil apoptosis in quiescent ANCA-associated systemic vasculitis

scientific article

Deficiency of the mannan-binding lectin pathway of complement and poor outcome in cystic fibrosis: bacterial colonization may be decisive for a relationship

scientific article published in February 2005

Development and validation of a consensus methodology for the classification of the ANCA-associated vasculitides and polyarteritis nodosa for epidemiological studies.

scientific article published on 10 August 2006

Diagnosis and classification of Goodpasture's disease (anti-GBM).

scientific article published on 21 January 2014

Different fractions of human serum glycoproteins bind galectin-1 or galectin-8, and their ratio may provide a refined biomarker for pathophysiological conditions in cancer and inflammatory disease

scientific article published on 17 January 2012

Effect of Treatment on Damage and Hospitalization in Elderly Patients with Microscopic Polyangiitis and Granulomatosis with Polyangiitis

scientific article published on 15 July 2019

Elevated neutrophil membrane expression of proteinase 3 is dependent upon CD177 expression

scientific article published on 10 May 2010

Epitope mapping of anti-PR3 antibodies using chimeric human/mouse PR3 recombinant proteins

scientific article

Epitope shift of proteinase-3 anti-neutrophil cytoplasmic antibodies in patients with small vessel vasculitis

scientific article published on 06 January 2010

Excellent long time survival for Swedish patients starting home-hemodialysis with and without subsequent renal transplantations.

scientific article published on 11 April 2013

Expression of p300-truncated fragments results in the modulation of apoptosis in rat mesangial cells.

scientific article

Extensive Endoscopic Image-Guided Sinus Surgery Decreases BPI-ANCA in Patients with Cystic Fibrosis

scientific article published on 01 December 2012

Galectin-8 in IgA nephritis: decreased binding of IgA by galectin-8 affinity chromatography and associated increased binding in non-IgA serum glycoproteins.

scientific article published on 16 December 2011

Genes that link nephritis to autoantibodies and innate immunity

scientific article published on 01 February 2011

Genetically distinct subsets within ANCA-associated vasculitis

scientific journal article

Higher levels of SDMA and not ADMA are associated with poorer survival of trial patients with systemic ANCA-associated vasculitis

scientific article published on 02 April 2018

Identification of a clinically relevant immunodominant region of collagen IV in Goodpasture disease.

scientific article

In Reply to 'IgG4-Restricted Anti-Glomerular Basement Membrane Autoantibodies Targeting Quaternary Epitopes of Native α345(IV) Collagen'

scientific article published on 01 July 2014

Incidence and disease severity of anti-neutrophil cytoplasmic antibody-associated nephritis are higher than in lupus nephritis in Sweden

scientific article published on 23 December 2014

Incidence and survival rates in Wegener's granulomatosis, microscopic polyangiitis, Churg-Strauss syndrome and polyarteritis nodosa.

scientific article

Incidence, prevalence and clinical characteristics of Behcet's disease in southern Sweden

scientific article published on 25 September 2012

Increased expression of the secretory leukocyte proteinase inhibitor in Wegener's granulomatosis.

scientific article

Increased neutrophil membrane expression and plasma level of proteinase 3 in systemic vasculitis are not a consequence of the - 564 A/G promotor polymorphism.

scientific article

L23. Renal transplantation in ANCA-associated vasculitis.

scientific article published on March 2013

Levels of epitope-specific autoantibodies correlate with renal damage in anti-GBM disease.

scientific article published on 16 January 2009

Monitoring proteinase 3 antineutrophil cytoplasmic antibodies for detection of relapses in small vessel vasculitis.

scientific article published in September 2003

Natural anti-GBM antibodies from normal human sera recognize alpha3(IV)NC1 restrictively and recognize the same epitopes as anti-GBM antibodies from patients with anti-GBM disease

scientific article published on 06 June 2007

Natural autoantibodies to myeloperoxidase, proteinase 3, and the glomerular basement membrane are present in normal individuals

scientific article published on 30 June 2010

Neutrophils from vasculitis patients exhibit an increased propensity for activation by anti-neutrophil cytoplasmic antibodies.

scientific article published in June 2014

Novel distribution of the secretory leucocyte proteinase inhibitor in kidney

scientific article published on December 2001

Phagocytosis of apoptotic cells by macrophages in anti-neutrophil cytoplasmic antibody-associated systemic vasculitis

scientific article published on 01 October 2012

Preeclampsia is associated with a reduced response to activated protein C

scientific article published on 01 February 1997

Prevalence of Wegener's granulomatosis, microscopic polyangiitis, polyarteritis nodosa and Churg-Strauss syndrome within a defined population in southern Sweden.

scientific article published on 6 June 2007

Primary systemic vasculitis with severe α1-antitrypsin deficiency revisited

scientific article published on 9 December 2013

Proteinase 3 and CD177 are expressed on the plasma membrane of the same subset of neutrophils

scientific article published on 31 October 2006

Pseudomonas aeruginosa in cystic fibrosis: pyocyanin negative strains are associated with BPI-ANCA and progressive lung disease.

scientific article published on 3 April 2011

Recurrent ANCA-associated small vessel vasculitis after transplantation: A pooled analysis

scientific article published on 01 October 1999

Replacement of acetate with citrate in dialysis fluid: a randomized clinical trial of short term safety and fluid biocompatibility

scientific article

Successful treatment of experimental glomerulonephritis with IdeS and EndoS, IgG-degrading streptococcal enzymes

scientific article published on 10 March 2010

The extent and pattern of organ damage in small vessel vasculitis measured by the Vasculitis Damage Index (VDI).

scientific article published in January 2009

The neutrophil serine protease PR3 induces shape change of platelets via the Rho/Rho kinase and Ca(2+) signaling pathways.

scientific article

Thirty-five years of hemodialysis: two case reports as a tribute to Nils Alwall

scientific article

Treatment of severe renal disease in ANCA positive and negative small vessel vasculitis with rituximab.

scientific article published on 2 June 2015

Urine IgM excretion predicts outcome in ANCA-associated renal vasculitis.

scientific article published on 31 January 2006

List of works by Mårten Segelmark

A candidate gene approach to ANCA-associated vasculitis reveals links to the C3 and CTLA-4 genes but not to the IL1-Ra and Fcγ-RIIa genes.

A myelopoiesis gene signature during remission in anti-neutrophil cytoplasm antibody-associated vasculitis does not predict relapses but seems to reflect ongoing prednisolone therapy.

A population-based study showing better renal prognosis for proteinase 3 antineutrophil cytoplasmic antibody (ANCA)-associated nephritis versus myeloperoxidase ANCA-associated nephritis.

ANCA antigens, proteinase 3 and myeloperoxidase, are not expressed in endothelial cells

Anti-GBM antibodies in Goodpasture syndrome; anatomy of an epitope

Anti-GBM disease with a mild relapsing course and low levels of anti-GBM autoantibodies

Antigen and epitope specificity of anti-glomerular basement membrane antibodies in patients with goodpasture disease with or without anti-neutrophil cytoplasmic antibodies.

Association of cigarette smoking with organ damage in primary systemic vasculitis

Autoantibody response to BPI predict disease severity and outcome in cystic fibrosis

Autoimmune kidney diseases

BPI-ANCA and long-term prognosis among 46 adult CF patients: a prospective 10-year follow-up study.

C3 and C4 allotypes in anti-neutrophil cytoplasmic autoantibody (ANCA)-positive vasculitis

Circulating anti-glomerular basement membrane antibodies with predominance of subclass IgG4 and false-negative immunoassay test results in anti-glomerular basement membrane disease

Circulating cytokine profile in anti-neutrophilic cytoplasmatic autoantibody-associated vasculitis: prediction of outcome?

Clinical evaluation of a capture ELISA for detection of proteinase-3 antineutrophil cytoplasmic antibody

Decreased neutrophil apoptosis in quiescent ANCA-associated systemic vasculitis

Deficiency of the mannan-binding lectin pathway of complement and poor outcome in cystic fibrosis: bacterial colonization may be decisive for a relationship

Development and validation of a consensus methodology for the classification of the ANCA-associated vasculitides and polyarteritis nodosa for epidemiological studies.

Diagnosis and classification of Goodpasture's disease (anti-GBM).

Different fractions of human serum glycoproteins bind galectin-1 or galectin-8, and their ratio may provide a refined biomarker for pathophysiological conditions in cancer and inflammatory disease

Effect of Treatment on Damage and Hospitalization in Elderly Patients with Microscopic Polyangiitis and Granulomatosis with Polyangiitis

Elevated neutrophil membrane expression of proteinase 3 is dependent upon CD177 expression

Epitope mapping of anti-PR3 antibodies using chimeric human/mouse PR3 recombinant proteins

Epitope shift of proteinase-3 anti-neutrophil cytoplasmic antibodies in patients with small vessel vasculitis

Excellent long time survival for Swedish patients starting home-hemodialysis with and without subsequent renal transplantations.

Expression of p300-truncated fragments results in the modulation of apoptosis in rat mesangial cells.

Extensive Endoscopic Image-Guided Sinus Surgery Decreases BPI-ANCA in Patients with Cystic Fibrosis

Galectin-8 in IgA nephritis: decreased binding of IgA by galectin-8 affinity chromatography and associated increased binding in non-IgA serum glycoproteins.

Genes that link nephritis to autoantibodies and innate immunity

Genetically distinct subsets within ANCA-associated vasculitis

Higher levels of SDMA and not ADMA are associated with poorer survival of trial patients with systemic ANCA-associated vasculitis

Identification of a clinically relevant immunodominant region of collagen IV in Goodpasture disease.

In Reply to 'IgG4-Restricted Anti-Glomerular Basement Membrane Autoantibodies Targeting Quaternary Epitopes of Native α345(IV) Collagen'

Incidence and disease severity of anti-neutrophil cytoplasmic antibody-associated nephritis are higher than in lupus nephritis in Sweden

Incidence and survival rates in Wegener's granulomatosis, microscopic polyangiitis, Churg-Strauss syndrome and polyarteritis nodosa.

Incidence, prevalence and clinical characteristics of Behcet's disease in southern Sweden

Increased expression of the secretory leukocyte proteinase inhibitor in Wegener's granulomatosis.

Increased neutrophil membrane expression and plasma level of proteinase 3 in systemic vasculitis are not a consequence of the - 564 A/G promotor polymorphism.

L23. Renal transplantation in ANCA-associated vasculitis.

Levels of epitope-specific autoantibodies correlate with renal damage in anti-GBM disease.

Monitoring proteinase 3 antineutrophil cytoplasmic antibodies for detection of relapses in small vessel vasculitis.

Natural anti-GBM antibodies from normal human sera recognize alpha3(IV)NC1 restrictively and recognize the same epitopes as anti-GBM antibodies from patients with anti-GBM disease

Natural autoantibodies to myeloperoxidase, proteinase 3, and the glomerular basement membrane are present in normal individuals

Neutrophils from vasculitis patients exhibit an increased propensity for activation by anti-neutrophil cytoplasmic antibodies.

Novel distribution of the secretory leucocyte proteinase inhibitor in kidney

Phagocytosis of apoptotic cells by macrophages in anti-neutrophil cytoplasmic antibody-associated systemic vasculitis

Preeclampsia is associated with a reduced response to activated protein C

Prevalence of Wegener's granulomatosis, microscopic polyangiitis, polyarteritis nodosa and Churg-Strauss syndrome within a defined population in southern Sweden.

Primary systemic vasculitis with severe α1-antitrypsin deficiency revisited

Proteinase 3 and CD177 are expressed on the plasma membrane of the same subset of neutrophils

Pseudomonas aeruginosa in cystic fibrosis: pyocyanin negative strains are associated with BPI-ANCA and progressive lung disease.

Recurrent ANCA-associated small vessel vasculitis after transplantation: A pooled analysis

Replacement of acetate with citrate in dialysis fluid: a randomized clinical trial of short term safety and fluid biocompatibility

Successful treatment of experimental glomerulonephritis with IdeS and EndoS, IgG-degrading streptococcal enzymes

The extent and pattern of organ damage in small vessel vasculitis measured by the Vasculitis Damage Index (VDI).

The neutrophil serine protease PR3 induces shape change of platelets via the Rho/Rho kinase and Ca(2+) signaling pathways.

Thirty-five years of hemodialysis: two case reports as a tribute to Nils Alwall

Treatment of severe renal disease in ANCA positive and negative small vessel vasculitis with rituximab.

Urine IgM excretion predicts outcome in ANCA-associated renal vasculitis.