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List of works by Philipp Koch

A Little Bit of Guidance: Mini Brains on Their Route to Adolescence

scientific article

A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat

scientific article

A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration

scholarly article

APP processing in human pluripotent stem cell-derived neurons is resistant to NSAID-based γ-secretase modulation.

scientific article published on 5 December 2013

An Organoid-Based Model of Cortical Development Identifies Non-Cell-Autonomous Defects in Wnt Signaling Contributing to Miller-Dieker Syndrome

scientific article published on April 2017

Anticancer effects of niclosamide in human glioblastoma.

scientific article

Arylsulfatase A Overexpressing Human iPSC-derived Neural Cells Reduce CNS Sulfatide Storage in a Mouse Model of Metachromatic Leukodystrophy

scientific article published on 10 June 2015

Asymmetric Notch activity by differential inheritance of lysosomes in human neural stem cells

scientific article published on 11 February 2022

Auto-attraction of neural precursors and their neuronal progeny impairs neuronal migration

scientific article

Bivalent histone modifications in stem cells poise miRNA loci for CpG island hypermethylation in human cancer

scientific article

C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility

scientific article published on 09 April 2021

Capture of neuroepithelial-like stem cells from pluripotent stem cells provides a versatile system for in vitro production of human neurons

scientific article

Cortical organoids: why all this hype?

scientific article published on 07 June 2018

DNA methylation alterations in iPSC- and hESC-derived neurons: potential implications for neurological disease modeling.

scientific article published on 29 January 2018

Direct Conversion Provides Old Neurons from Aged Donor's Skin

scientific article published on 01 December 2015

Embryonic stem cell-based modeling of tau pathology in human neurons.

scientific article published on 13 March 2013

Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis

scientific article published on 13 June 2019

Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease

scientific article published on 23 November 2011

Functional neuronal cells generated by human parthenogenetic stem cells

scientific article

Generation of Standardized and Reproducible Forebrain-type Cerebral Organoids from Human Induced Pluripotent Stem Cells

scientific article published on 23 January 2018

Generation of functional human serotonergic neurons from fibroblasts

scientific article published on 27 October 2015

Genome Editing in Neuroepithelial Stem Cells to Generate Human Neurons with High Adenosine-Releasing Capacity.

scientific article

Human embryonic stem cell-derived neurons establish region-specific, long-range projections in the adult brain.

scientific article published on 21 July 2011

Human induced pluripotent stem cell-derived cortical neurons integrate in stroke-injured cortex and improve functional recovery

scientific article published on 21 October 2013

Human induced pluripotent stem cells improve recovery in stroke-injured aged rats.

scientific article

Human-induced pluripotent stem cells form functional neurons and improve recovery after grafting in stroke-damaged brain

scientific article

In Vitro Recapitulation of Developmental Transitions in Human Neural Stem Cells

scientific article published on 24 August 2019

In vitro segregation and isolation of human pluripotent stem cell-derived neural crest cells

scientific article published on 13 October 2017

Induction of Amyloid-β42 Production by Fipronil and Other Pyrazole Insecticides

scientific article published on 28 February 2018

Inhibition of notch signaling in human embryonic stem cell-derived neural stem cells delays G1/S phase transition and accelerates neuronal differentiation in vitro and in vivo.

scientific article published on May 2010

Interinstitutional variance of postoperative radiotherapy and follow up for meningiomas in Germany: impact of changes of the WHO classification.

scientific article

Laser-assisted photoablation of human pluripotent stem cells from differentiating cultures

scientific article

Leveling Waddington: the emergence of direct programming and the loss of cell fate hierarchies ⬇️

scientific article published on 13 March 2013

Lineage selection of functional and cryopreservable human embryonic stem cell-derived neurons

scientific article published on 17 April 2008

MTSS1 is epigenetically regulated in glioma cells and inhibits glioma cell motility.

scientific article published on 15 December 2016

MicroRNA-based promotion of human neuronal differentiation and subtype specification

scientific article

Nucleofection of human embryonic stem cells

scientific article published in January 2008

Nucleofection of human embryonic stem cells.

scientific article published on August 2005

Optogenetics reveal delayed afferent synaptogenesis on grafted human-induced pluripotent stem cell-derived neural progenitors

scientific article published in December 2014

Phosphorylation of the amyloid β-peptide at Ser26 stabilizes oligomeric assembly and increases neurotoxicity.

scientific article published on 22 February 2016

Pluripotent stem cell-derived somatic stem cells as tool to study the role of microRNAs in early human neural development.

scientific article published on June 2013

Presenilin-1 L166P mutant human pluripotent stem cell-derived neurons exhibit partial loss of γ-secretase activity in endogenous amyloid-β generation.

scientific article published on 14 April 2012

Reactivation of mutant p53 by a one-hybrid adaptor protein.

scientific article published in July 2003

Small molecules enable highly efficient neuronal conversion of human fibroblasts

scientific article

Specific Inhibition of β-Secretase Processing of the Alzheimer Disease Amyloid Precursor Protein

scientific article

Specific Triazine Herbicides Induce Amyloid-β42 Production

scientific article

Suppression of kindling epileptogenesis by adenosine releasing stem cell-derived brain implants.

scientific article

Targeting the cytosolic innate immune receptors RIG-I and MDA5 effectively counteracts cancer cell heterogeneity in glioblastoma

scientific article published on June 2013

The Alzheimer's Disease γ-Secretase Generates Higher 42:40 Ratios for β-Amyloid Than for p3 Peptides

scientific article published in June 2017

The different moods of human serotonergic neurons.

scientific article published in January 2016

Transduction of human embryonic stem cells by ecotropic retroviral vectors.

scientific article published on 22 September 2006

Tumor-derived mutations within the DNA-binding domain of p53 that phenotypically resemble the deletion of the proline-rich domain

scientific article published on 01 March 2000

Whole-brain 3D mapping of human neural transplant innervation.

scientific article

p66(ShcA) adaptor molecule accelerates ES cell neural induction

scientific article

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