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List of works by Graham Ladds

A temperature-sensitive Krp1 allows in vivo characterization of kexin activation

scientific article published on 01 August 2000

An efficient bipartite PCR technique to introduce specific changes in large plasmids.

scientific article published in November 2004

Author Correction: Combinatorial expression of GPCR isoforms affects signalling and drug responses

scientific article published on 25 November 2020

BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma

scientific article published in Nature Communications

CGRP, adrenomedullin and adrenomedullin 2 display endogenous GPCR agonist bias in primary human cardiovascular cells

scientific article published on 23 June 2021

Combinatorial expression of GPCR isoforms affects signalling and drug responses

scientific article published on 04 November 2020

Combined use of two transcriptional reporters improves signalling assays for G protein-coupled receptors in fission yeast

scientific article published on 01 September 2006

Computer-aided design of multi-target ligands at A1R, A2AR and PDE10A, key proteins in neurodegenerative diseases

scientific article published on 30 December 2017

Correction to Discovery of Novel Adenosine Receptor Agonists That Exhibit Subtype Selectivity

scientific article published on 01 September 2020

Correction to Insights to the Binding of a Selective Adenosine A3 Receptor Antagonist using Molecular Dynamic Simulations, MM-PBSA and MM-GBSA Free Energy Calculations, and Mutagenesis

scientific article published on 25 March 2020

Cortical oscillatory dynamics and benzodiazepine-site modulation of tonic inhibition in fast spiking interneurons.

scientific article published on 20 March 2015

Corticotropin-releasing hormone receptors

scientific article

Development of a semi-quantitative plate-based alpha-galactosidase gene reporter for Schizosaccharomyces pombe and its use to isolate a constitutively active Mam2.

scientific article published in January 2005

Differential effects of RGS proteins on Gαq and Gα11 activity

article

Discovery of Novel Adenosine Receptor Agonists That Exhibit Subtype Selectivity.

scientific article

Dual positive and negative regulation of GPCR signaling by GTP hydrolysis.

scientific article published on 12 March 2009

Emerging patents in the therapeutic areas of glioma and glioblastoma.

scientific article

Engineering a model cell for rational tuning of GPCR signaling

scientific article published on 13 August 2018

Extracellular degradation of agonists as an adaptive mechanism

scientific article published on 01 April 1998

Feedback activation of neurofibromin terminates growth factor-induced Ras activation.

scientific article published on 9 February 2016

Folding-competent and folding-defective forms of ricin A chain have different fates after retrotranslocation from the endoplasmic reticulum

scientific article

GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation

scientific article

Heterologous expression of GPCRs in fission yeast

scientific article published in January 2011

Hyperglycaemia does not affect antigen-specific activation and cytolytic killing by CD8+ T cells in vivo

scientific article published on 10 August 2017

Identification of proteases with shared functions to the proprotein processing protease Krp1 in the fission yeast Schizosaccharomyces pombe.

scientific article published on November 2000

Identifying regulators of pheromone signalling in the fission yeast Schizosaccharomyces pombe

scientific article published on 25 June 2002

Image based validation of dynamical models for cell reorientation.

scientific article

Insights to the Binding of a Selective Adenosine A3 Receptor Antagonist Using Molecular Dynamic Simulations, MM-PBSA and MM-GBSA Free Energy Calculations, and Mutagenesis

scientific article published on 03 December 2019

Investigating G protein signalling bias at the glucagon-like peptide-1 receptor in yeast

scientific article published on August 2014

Investigating RGS proteins in yeast.

scientific article

Modelling and simulation of biased agonism dynamics at a G protein-coupled receptor.

scientific article published on 11 January 2018

Modulation of Glucagon Receptor Pharmacology by Receptor Activity-modifying Protein-2 (RAMP2).

scientific article published on 21 July 2015

One motif to bind them: A small-XXX-small motif affects transmembrane domain 1 oligomerization, function, localization, and cross-talk between two yeast GPCRs

scientific article published on 23 August 2014

Paracrine oxytocin and estradiol demonstrate a spatial increase in human intrauterine tissues with labor.

scientific article published on July 2003

Parameter identification problems in the modelling of cell motility

scientific article published on 2 September 2014

Quantitative analysis of human ras localization and function in the fission yeast Schizosaccharomyces pombe.

scientific article

RAMP3 determines rapid recycling of atypical chemokine receptor-3 for guided angiogenesis

scientific article published on 11 November 2019

Ras activation revisited: role of GEF and GAP systems.

scientific article published on August 2015

Receptor Activity-modifying Protein-directed G Protein Signaling Specificity for the Calcitonin Gene-related Peptide Family of Receptors

scientific article published on 14 October 2016

Receptor activity-modifying protein-directed G protein signaling specificity for the calcitonin gene-related peptide family of receptors

scientific article published on December 2016

Receptor activity-modifying proteins; multifunctional G protein-coupled receptor accessory proteins.

scientific article published on April 2016

Regulators of G protein signalling proteins in the human myometrium

scientific article published on 24 March 2009

Structure-based identification of dual ligands at the A<sub>2A</sub>R and PDE10A with anti-proliferative effects in lung cancer cell-lines

scientific article published on 03 March 2021

Sxa2 is a serine carboxypeptidase that degrades extracellular P-factor in the fission yeast Schizosaccharomyces pombe

scientific article published on 01 April 2000

The cationic region of Rhes mediates its interactions with specific Gbeta subunits

scientific article

The coordination of cell growth during fission yeast mating requires Ras1-GTP hydrolysis

scientific article

The effects of RAMPs upon cell signalling

scientific article published on 5 April 2017

The processing of yeast pheromones

scientific article published on 01 February 1998

The role of the RACK1 ortholog Cpc2p in modulating pheromone-induced cell cycle arrest in fission yeast.

scientific article

The sxa2-dependent inactivation of the P-factor mating pheromone in the fission yeast Schizosaccharomyces pombe

scientific article published on 01 April 1996

Utilisation of the budding yeast Saccharomyces cerevisiae for the generation and isolation of non-lethal ricin A chain variants

scientific article published on 01 December 2005

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