List of works - Frédéric Charron

14-3-3 proteins regulate a cell-intrinsic switch from sonic hedgehog-mediated commissural axon attraction to repulsion after midline crossing

scientific article published in November 2012

14-3-3 proteins regulate protein kinase a activity to modulate growth cone turning responses

scientific article published in October 2010

A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease

scientific journal article

A novel conserved evx1 enhancer links spinal interneuron morphology and cis-regulation from fish to mammals.

scientific article published on 18 October 2008

Axon Guidance: Gained in Translation

scientific article published on 01 July 2018

Boc is a receptor for sonic hedgehog in the guidance of commissural axons

scientific journal article

Cardiac tissue enriched factors serum response factor and GATA-4 are mutual coregulators

scientific article

Cellular Functions of the Autism Risk Factor PTCHD1 in Mice.

scientific article published on 8 November 2017

De Novo Pathogenic Variants in N-cadherin Cause a Syndromic Neurodevelopmental Disorder with Corpus Collosum, Axon, Cardiac, Ocular, and Genital Defects

scientific article published on 01 October 2019

Dissection and culture of commissural neurons from embryonic spinal cord

scientific article published on 25 May 2010

Dscam guides embryonic axons by Netrin-dependent and -independent functions

scientific article published on 23 October 2008

Evasion of Cell Senescence Leads to Medulloblastoma Progression

scientific article

Evasion of cell senescence in SHH medulloblastoma.

scientific article published on 26 May 2016

Extracellular phosphorylation in axon pathfinding

scientific article published on 01 November 2019

GATA-4 is a nuclear mediator of mechanical stretch-activated hypertrophic program

scientific journal article

Ihog and Boi are essential for Hedgehog signaling in Drosophila.

scientific article

Ihog and Boi elicit Hh signaling via Ptc but do not aid Ptc in sequestering the Hh ligand

scientific article

Integration of shallow gradients of Shh and Netrin-1 guides commissural axons.

scientific article published on 31 March 2015

Lateralization of motor control in the human nervous system: genetics of mirror movements.

scientific article published on 16 September 2012

Linking Hedgehog, Translation, and mTORC1 in Medulloblastoma

scientific article published in December 2017

Long-Range Guidance of Spinal Commissural Axons by Netrin1 and Sonic Hedgehog from Midline Floor Plate Cells

scientific article published on 17 January 2019

Loss of Dcc in the Spinal Cord is Sufficient to Cause a Deficit in Lateralized Motor Control and the Switch to a Hopping Gait.

scientific article

Mesocortical Dopamine Phenotypes in Mice Lacking the Sonic Hedgehog Receptor Cdon

scientific article

Midline axon guidance and human genetic disorders ⬇️

scientific article published on July 25, 2011

Mutations in DCC cause congenital mirror movements.

scientific article

N-cadherin relocalizes from the periphery to the center of the synapse after transient synaptic stimulation in hippocampal neurons

scientific article

Neurons diversify astrocytes in the adult brain through sonic hedgehog signaling.

scientific article published in February 2016

Neurotrophins and netrins require calcineurin/NFAT signaling to stimulate outgrowth of embryonic axons

scientific article (publication date: 30 May 2003)

Novel brain wiring functions for classical morphogens: a role as graded positional cues in axon guidance.

scientific article

Numb positively regulates Hedgehog signaling at the ciliary pocket

scientific article published in 2024

Overexpression of Desmoglein 2 in a mouse model of Gorlin syndrome enhances spontaneous basal cell carcinoma formation through STAT3-mediated Gli1 expression ⬇️

article

Pioneer midbrain longitudinal axons navigate using a balance of Netrin attraction and Slit repulsion.

scientific article

Polarized Dock Activity Drives Shh-Mediated Axon Guidance

scientific article published on 02 August 2018

Recent advances in SHH medulloblastoma progression: tumor suppressor mechanisms and the tumor microenvironment

scientific article published on 29 October 2019

Segregation of ipsilateral retinal ganglion cell axons at the optic chiasm requires the Shh receptor Boc

scientific journal article

Signaling from Within: Endocytic Trafficking of the Robo Receptor Is Required for Midline Axon Repulsion

scientific article published on 3 September 2015

Signaling mechanisms of non-conventional axon guidance cues: the Shh, BMP and Wnt morphogens.

scientific article published on 29 October 2013

Sonic Hedgehog Guides Axons via Zipcode Binding Protein 1-Mediated Local Translation.

scientific article published on 10 January 2017

Sonic Hedgehog Is a Remotely Produced Cue that Controls Axon Guidance Trans-axonally at a Midline Choice Point

scientific article published in January 2018

Sonic hedgehog guides axons through a noncanonical, Src-family-kinase-dependent signaling pathway

scientific journal article

Switching responses: spatial and temporal regulators of axon guidance.

scientific article

Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons

scientific article published on 03 December 2015

The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence

scientific article

The Hedgehog, TGF-beta/BMP and Wnt families of morphogens in axon guidance.

scientific article published on January 2007

The Shh receptor Boc promotes progression of early medulloblastoma to advanced tumors

scientific article published on 25 September 2014

The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors

scientific article

The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance

scientific journal article

Tissue-specific GATA factors are transcriptional effectors of the small GTPase RhoA

scientific article

Transcription factor SCL is required for c-kit expression and c-Kit function in hemopoietic cells.

scientific article

VEGF mediates commissural axon chemoattraction through its receptor Flk1.

scientific article published on June 2011

[Sonic hedgehog and Boc: a very attractive story about axons]

scientific article published on 01 February 2008

[VEGF guides commissural axons: a classic blood vessel trophic factor on the nerve's service]

scientific article published on 23 December 2011

List of works by Frédéric Charron

14-3-3 proteins regulate a cell-intrinsic switch from sonic hedgehog-mediated commissural axon attraction to repulsion after midline crossing

14-3-3 proteins regulate protein kinase a activity to modulate growth cone turning responses

A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease

A novel conserved evx1 enhancer links spinal interneuron morphology and cis-regulation from fish to mammals.

Axon Guidance: Gained in Translation

Boc is a receptor for sonic hedgehog in the guidance of commissural axons

Cardiac tissue enriched factors serum response factor and GATA-4 are mutual coregulators

Cellular Functions of the Autism Risk Factor PTCHD1 in Mice.

De Novo Pathogenic Variants in N-cadherin Cause a Syndromic Neurodevelopmental Disorder with Corpus Collosum, Axon, Cardiac, Ocular, and Genital Defects

Dissection and culture of commissural neurons from embryonic spinal cord

Dscam guides embryonic axons by Netrin-dependent and -independent functions

Evasion of Cell Senescence Leads to Medulloblastoma Progression

Evasion of cell senescence in SHH medulloblastoma.

Extracellular phosphorylation in axon pathfinding

GATA-4 is a nuclear mediator of mechanical stretch-activated hypertrophic program

Ihog and Boi are essential for Hedgehog signaling in Drosophila.

Ihog and Boi elicit Hh signaling via Ptc but do not aid Ptc in sequestering the Hh ligand

Integration of shallow gradients of Shh and Netrin-1 guides commissural axons.

Lateralization of motor control in the human nervous system: genetics of mirror movements.

Linking Hedgehog, Translation, and mTORC1 in Medulloblastoma

Long-Range Guidance of Spinal Commissural Axons by Netrin1 and Sonic Hedgehog from Midline Floor Plate Cells

Loss of Dcc in the Spinal Cord is Sufficient to Cause a Deficit in Lateralized Motor Control and the Switch to a Hopping Gait.

Mesocortical Dopamine Phenotypes in Mice Lacking the Sonic Hedgehog Receptor Cdon

Midline axon guidance and human genetic disorders ⬇️

Mutations in DCC cause congenital mirror movements.

N-cadherin relocalizes from the periphery to the center of the synapse after transient synaptic stimulation in hippocampal neurons

Neurons diversify astrocytes in the adult brain through sonic hedgehog signaling.

Neurotrophins and netrins require calcineurin/NFAT signaling to stimulate outgrowth of embryonic axons

Novel brain wiring functions for classical morphogens: a role as graded positional cues in axon guidance.

Numb positively regulates Hedgehog signaling at the ciliary pocket

Overexpression of Desmoglein 2 in a mouse model of Gorlin syndrome enhances spontaneous basal cell carcinoma formation through STAT3-mediated Gli1 expression ⬇️

Pioneer midbrain longitudinal axons navigate using a balance of Netrin attraction and Slit repulsion.

Polarized Dock Activity Drives Shh-Mediated Axon Guidance

Recent advances in SHH medulloblastoma progression: tumor suppressor mechanisms and the tumor microenvironment

Segregation of ipsilateral retinal ganglion cell axons at the optic chiasm requires the Shh receptor Boc

Signaling from Within: Endocytic Trafficking of the Robo Receptor Is Required for Midline Axon Repulsion

Signaling mechanisms of non-conventional axon guidance cues: the Shh, BMP and Wnt morphogens.

Sonic Hedgehog Guides Axons via Zipcode Binding Protein 1-Mediated Local Translation.

Sonic Hedgehog Is a Remotely Produced Cue that Controls Axon Guidance Trans-axonally at a Midline Choice Point

Sonic hedgehog guides axons through a noncanonical, Src-family-kinase-dependent signaling pathway

Switching responses: spatial and temporal regulators of axon guidance.

Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons

The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence

The Hedgehog, TGF-beta/BMP and Wnt families of morphogens in axon guidance.

The Shh receptor Boc promotes progression of early medulloblastoma to advanced tumors

The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors

The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance

Tissue-specific GATA factors are transcriptional effectors of the small GTPase RhoA

Transcription factor SCL is required for c-kit expression and c-Kit function in hemopoietic cells.

VEGF mediates commissural axon chemoattraction through its receptor Flk1.

[Sonic hedgehog and Boc: a very attractive story about axons]

[VEGF guides commissural axons: a classic blood vessel trophic factor on the nerve's service]