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List of works by Baldomero Olivera

A bacterial source for mollusk pyrone polyketides ⬇️

scientific article published on January 2013

A disulfide tether stabilizes the block of sodium channels by the conotoxin μO§-GVIIJ.

scientific article published on 04 February 2014

A family of excitatory peptide toxins from venomous crassispirine snails: using Constellation Pharmacology to assess bioactivity

scientific article

A marine analgesic peptide, Contulakin-G, and neurotensin are distinct agonists for neurotensin receptors: uncovering structural determinants of desensitization properties

scientific article

A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin

scientific article

A new species of Casmaria H. Adams & A. Adams, 1853 (Gastropoda, Cassidae) from the Philippines identified by molecular data

scientific article published on 28 March 2014

A novel Conus snail polypeptide causes excitotoxicity by blocking desensitization of AMPA receptors

scientific article

A novel alpha conotoxin (alpha-PIB) isolated from C. purpurascens is selective for skeletal muscle nicotinic acetylcholine receptors

scientific article published on 24 February 2007

A novel alpha-conotoxin, PeIA, cloned from Conus pergrandis, discriminates between rat alpha9alpha10 and alpha7 nicotinic cholinergic receptors

scientific article published on 27 June 2005

A novel arrangement of Cys residues in a paralytic peptide of Conus cancellatus (jr. syn.: Conus austini), a worm-hunting snail from the Gulf of Mexico ⬇️

scientific article published on March 7, 2013

A novel conotoxin from Conus delessertii with posttranslationally modified lysine residues

scientific article published in August 2005

A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins.

scientific article published in July 2006

A novel conus peptide ligand for K+ channels

scientific article published on 23 October 2002

A novel structural class of toxins: the methionine-rich peptides from the venoms of turrid marine snails (Mollusca, Conoidea).

scientific article published in March 2004

A rapidly diverging superfamily of peptide toxins in venomous Gemmula species

scientific article

A structurally minimized yet fully active insulin based on cone-snail venom insulin principles

scientific article published on 01 June 2020

A uniquely selective inhibitor of the mammalian fetal neuromuscular nicotinic acetylcholine receptor

scientific article

A very short, functionally constrained sequence diagnoses cone snails in several Conasprella clades ⬇️

scientific article published on June 26, 2012

Adaptive radiation of venomous marine snail lineages and the accelerated evolution of venom peptide genes ⬇️

scientific article published on September 1, 2012

Against expectation: A short sequence with high signal elucidates cone snail phylogeny ⬇️

scientific article (publication date: February 2011)

Alpha S-conotoxin RVIIIA: a structurally unique conotoxin that broadly targets nicotinic acetylcholine receptors

scientific article published in May 2005

Alpha-RgIA: a novel conotoxin that specifically and potently blocks the alpha9alpha10 nAChR.

scientific article published in February 2006

Alpha-conotoxin BuIA, a novel peptide from Conus bullatus, distinguishes among neuronal nicotinic acetylcholine receptors

scientific article published in November 2004

Alpha-conotoxin GIC from Conus geographus, a novel peptide antagonist of nicotinic acetylcholine receptors

scientific article

Alpha-conotoxin OmIA is a potent ligand for the acetylcholine-binding protein as well as alpha3beta2 and alpha7 nicotinic acetylcholine receptors

scientific article published on 27 June 2006

Alpha-conotoxin PIA is selective for alpha6 subunit-containing nicotinic acetylcholine receptors.

scientific article published in September 2003

Alpha-conotoxins ImI and ImII target distinct regions of the human alpha7 nicotinic acetylcholine receptor and distinguish human nicotinic receptor subtypes

scientific article published in December 2004

Alpha-conotoxins ImI and ImII. Similar alpha 7 nicotinic receptor antagonists act at different sites

scientific article published on 15 October 2002

Alpha4/3 conotoxins: phylogenetic distribution, functional properties, and structure-function insights

scientific article published on January 2007

AlphaA-Conotoxin OIVA defines a new alphaA-conotoxin subfamily of nicotinic acetylcholine receptor inhibitors

scientific article published on August 2004

AlphaC-conotoxin PrXA: a new family of nicotinic acetylcholine receptor antagonists

scientific article

Amino acid sequence and biological activity of a gamma-conotoxin-like peptide from the worm-hunting snail Conus austini

scientific article published on 2 December 2005

An O-conotoxin from the vermivorous Conus spurius active on mice and mollusks

scientific article

An integrative approach to the facile functional classification of dorsal root ganglion neuronal subclasses

scientific article published on 20 February 2020

Author Correction: A structurally minimized yet fully active insulin based on cone-snail venom insulin principles

scientific article published on 12 June 2020

Biochemical and gene expression analyses of conotoxins in Conus textile venom ducts

scientific article published on 01 March 2005

Biochemical characterization of kappaM-RIIIJ, a Kv1.2 channel blocker: evaluation of cardioprotective effects of kappaM-conotoxins

scientific article

Biodiversity of cone snails and other venomous marine gastropods: evolutionary success through neuropharmacology

scientific article

Characterization and three-dimensional structure determination of psi-conotoxin Piiif, a novel noncompetitive antagonist of nicotinic acetylcholine receptors

scientific article (publication date: 3 June 2003)

Characterization of D-amino-acid-containing excitatory conotoxins and redefinition of the I-conotoxin superfamily

scientific article

Characterization of a novel psi-conotoxin from Conus parius Reeve

scientific article published on 31 July 2007

Characterization of a venom peptide from a crassispirid gastropod ⬇️

scientific article published on September 12, 2011

Characterization of conantokin Rl-A: molecular phylogeny as structure/function study

scientific article

Characterization of the Conus bullatus genome and its venom-duct transcriptome ⬇️

scientific article published on January 25, 2011

Characterization of the First Conotoxin from Conus ateralbus, a Vermivorous Cone Snail from the Cabo Verde Archipelago

scientific article published on 24 July 2019

Characterization of the complete mitochondrial genome of Conus tribblei Walls, 1977.

scientific article published on 16 October 2015

Characterization of the peptidylglycine α-amidating monooxygenase (PAM) from the venom ducts of neogastropods, Conus bullatus and Conus geographus

scientific article

Characterization of two neuronal subclasses through constellation pharmacology ⬇️

scientific article published on July 9, 2012

Chronicling changes in the somatosensory neurons after peripheral nerve injury

scientific article published on 05 October 2020

Classifying neuronal subclasses of the cerebellum through constellation pharmacology

scientific article published on 18 November 2015

Combined proteomic and transcriptomic interrogation of the venom gland of Conus geographus uncovers novel components and functional compartmentalization

scientific article published on 29 January 2014

Comparison of the Venom Peptides and Their Expression in Closely Related Conus Species: Insights into Adaptive Post-speciation Evolution of Conus Exogenomes

scientific article

Complete mitochondrial DNA sequence of a Conoidean gastropod, Lophiotoma (Xenuroturris) cerithiformis: gene order and gastropod phylogeny

scientific article published on 5 May 2006

Conantokin-Br from Conus brettinghami and selectivity determinants for the NR2D subunit of the NMDA receptor

scientific article

Conantokin-L, a new NMDA receptor antagonist: determinants for anticonvulsant potency.

scientific article

Conantokin-P, an unusual conantokin with a long disulfide loop

scientific article

Conkunitzin-S1 is the first member of a new Kunitz-type neurotoxin family. Structural and functional characterization

scientific article published on 15 April 2005

Conopeptides promote itch through human itch receptor hMgprX1

scientific article published on 21 September 2018

Conorfamide-Sr2, a gamma-carboxyglutamate-containing FMRFamide-related peptide from the venom of Conus spurius with activity in mice and mollusks

scientific article published on 5 December 2007

Conotoxin κM-RIIIJ, a tool targeting asymmetric heteromeric Kv1 channels

scientific article published on 28 December 2018

Conotoxins containing nonnatural backbone spacers: cladistic-based design, chemical synthesis, and improved analgesic activity

scientific article published in April 2007

Conotoxins down under

scientific article published on 15 July 2006

Conus venoms - a rich source of peptide-based therapeutics

scientific article published on January 2008

Conus venoms: a rich source of novel ion channel-targeted peptides

scientific article

Cooccupancy of the outer vestibule of voltage-gated sodium channels by micro-conotoxin KIIIA and saxitoxin or tetrodotoxin

scientific article

Co‐expression of NaVβ subunits alters the kinetics of inhibition of voltage‐gated sodium channels by pore‐blocking μ‐conotoxins ⬇️

scientific article published on April 1, 2013

Curses or Cures: A Review of the Numerous Benefits Versus the Biosecurity Concerns of Conotoxin Research

scientific article published on 22 July 2020

Defining a Clade by Morphological, Molecular and Toxinological Criteria: Distinctive Forms related to Conus praecellens A. Adams, 1854.

scientific article

Defining modulatory inputs into CNS neuronal subclasses by functional pharmacological profiling

scientific article

Definition and characterization of the short alphaA-conotoxins: a single residue determines dissociation kinetics from the fetal muscle nicotinic acetylcholine receptor

scientific article

Discovery and characterization of the short kappaA-conotoxins: a novel subfamily of excitatory conotoxins

scientific article published on 14 October 2006

Discovery by proteogenomics and characterization of an RF-amide neuropeptide from cone snail venom

scientific article

Discovery, synthesis, and structure activity of a highly selective alpha7 nicotinic acetylcholine receptor antagonist

scientific article

Dissecting a role of evolutionary‐conserved but noncritical disulfide bridges in cysteine‐rich peptides using ω‐conotoxin GVIA and its selenocysteine analogs ⬇️

scientific article published on January 1, 2012

Distinct Disulfide Isomers of μ-Conotoxins KIIIA and KIIIB Block Voltage-Gated Sodium Channels

scientific article

Disulfide-Depleted Selenoconopeptides: a Minimalist Strategy to Oxidative Folding of Cysteine-Rich Peptides

scientific article published on May 2010

Divergence of the Venom Exogene Repertoire in Two Sister Species of Turriconus.

scientific article published on September 2017

Divergent M- and O-superfamily peptides from venom of fish-hunting Conus parius

scientific article

Efficient oxidative folding of conotoxins and the radiation of venomous cone snails

scientific article (publication date: 25 November 2003)

Elucidation of the molecular envenomation strategy of the cone snail Conus geographus through transcriptome sequencing of its venom duct ⬇️

scientific article published on June 28, 2012

Ero1-Mediated Reoxidation of Protein Disulfide Isomerase Accelerates the Folding of Cone Snail Toxins

scientific article published on 31 October 2018

Essential roles of the acetylcholine receptor gamma-subunit in neuromuscular synaptic patterning

scientific article

Fish-hunting cone snail venoms are a rich source of minimized ligands of the vertebrate insulin receptor

scientific article published on 12 February 2019

Functional profiling of neurons through cellular neuropharmacology ⬇️

scientific article published on January 23, 2012

Glycine-rich conotoxins from the Virgiconus clade

scientific article

Griseorhodins D-F, neuroactive intermediates and end products of post-PKS tailoring modification in Griseorhodin biosynthesis ⬇️

scientific article

High conopeptide diversity in Conus tribblei revealed through analysis of venom duct transcriptome using two high-throughput sequencing platforms

scientific article published on 13 August 2014

I(1)-superfamily conotoxins and prediction of single D-amino acid occurrence

scientific article published on 29 September 2007

I-conotoxins in vermivorous species of the West Atlantic: peptide sr11a from Conus spurius

scientific article

Identification of Conus peptidylprolyl cis-trans isomerases (PPIases) and assessment of their role in the oxidative folding of conotoxins

scientific article

Identification of a mammalian target of kappaM-conotoxin RIIIK.

scientific article published in June 2004

Insights into the origins of fish hunting in venomous cone snails from studies of Conus tessulatus

scientific article

Integrated oxidative folding of cysteine/selenocysteine containing peptides: improving chemical synthesis of conotoxins.

scientific article published on January 2009

Integrating Venom Peptide Libraries Into a Phylogenetic and Broader Biological Framework

scientific article published on 21 February 2022

Interactions of disulfide-deficient selenocysteine analogs of μ-conotoxin BuIIIB with the α-subunit of the voltage-gated sodium channel subtype 1.3.

scientific article

Linking neuroethology to the chemical biology of natural products: interactions between cone snails and their fish prey, a case study

scientific article

Mammalian Neuronal Sodium Channel Blocker μ-Conotoxin BuIIIB Has a Structured N-Terminus That Influences Potency

scientific article

Metabolic model for diversity-generating biosynthesis

scientific article published on February 2016

Microhabitats within venomous cone snails contain diverse actinobacteria

scientific article

Modulation of conotoxin structure and function is achieved through a multienzyme complex in the venom glands of cone snails

scientific article

Molecular characterization of frog vocal neurons using constellation pharmacology

scientific article published on 06 May 2020

Molecular mechanism for analgesia involving specific antagonism of alpha9alpha10 nicotinic acetylcholine receptors

scientific article

Mu-conotoxin SmIIIA, a potent inhibitor of tetrodotoxin-resistant sodium channels in amphibian sympathetic and sensory neurons

scientific article

Multiple 6-bromotryptophan residues in a sleep-inducing peptide

scientific article published in September 2004

Multiple genes elucidate the evolution of venomous snail-hunting Conus species

scientific article published on 16 July 2009

NMR structure determination of alpha-conotoxin BuIA, a novel neuronal nicotinic acetylcholine receptor antagonist with an unusual 4/4 disulfide scaffold

scientific article published on 07 September 2006

NMR-based mapping of disulfide bridges in cysteine-rich peptides: application to the mu-conotoxin SxIIIA

scientific article published on 03 October 2008

NaVβ Subunits Modulate the Inhibition of NaV1.8 by the Analgesic Gating Modifier μO-Conotoxin MrVIB ⬇️

scientific article published on May 17, 2011

Natural Products and Ion Channel Pharmacology ⬇️

scientific article published on May 1, 2010

Neuroactive diol and acyloin metabolites from cone snail-associated bacteria ⬇️

scientific article published on 08 July 2013

Neuroprotective and cardioprotective conopeptides: an emerging class of drug leads.

scientific article published on March 2009

Nobilamides A–H, Long-Acting Transient Receptor Potential Vanilloid-1 (TRPV1) Antagonists from Mollusk-Associated Bacteria ⬇️

scientific article published on May 16, 2011

Novel Conotoxins fromConus striatusandConus kinoshitaiSelectively Block TTX-Resistant Sodium Channels

scientific article published in 2006

Novel conantokins from Conus parius venom are specific antagonists of N-methyl-D-aspartate receptors

scientific article

Novel conotoxins from Conus striatus and Conus kinoshitai selectively block TTX-resistant sodium channels

scientific article published in May 2005

Novel excitatory Conus peptides define a new conotoxin superfamily.

scientific article

Novel venom peptides from the cone snail Conus pulicarius discovered through next-generation sequencing of its venom duct transcriptome

scientific article

Oxidative folding of conotoxins sharing an identical disulfide bridging framework

scientific article published in April 2005

Pain therapeutics from cone snail venoms: From Ziconotide to novel non-opioid pathways

scientific article published on 16 May 2018

Peptide pal9a from the venom of the turrid snail Polystira albida from the Gulf of Mexico: purification, characterization, and comparison with P-conotoxin-like (framework IX) conoidean peptides

scientific article published on 02 October 2008

Peptide-toxin tools for probing the expression and function of fetal and adult subtypes of the nicotinic acetylcholine receptor

scientific article published in January 2008

Pharmacological fractionation of tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons by μ-conotoxins ⬇️

scientific article published on May 1, 2013

Phylogeny of the genus Turris: correlating molecular data with radular anatomy and shell morphology

scientific article

Post-translational amino acid isomerization: a functionally important D-amino acid in an excitatory peptide

scientific article published on 23 November 2004

Prey-Capture Strategies of Fish-Hunting Cone Snails: Behavior, Neurobiology and Evolution

scientific article

Probing the Redox States of Sodium Channel Cysteines at the Binding Site of μO§-Conotoxin GVIIJ.

scientific article

Production of recombinant Conkunitzin-S1 in Escherichia coli

scientific article published on 20 February 2006

Prolongation of evoked and spontaneous synaptic currents at the neuromuscular junction after activity blockade is caused by the upregulation of fetal acetylcholine receptors.

scientific article published in August 2006

Propeptide does not act as an intramolecular chaperone but facilitates protein disulfide isomerase-assisted folding of a conotoxin precursor

scientific article published on 01 February 2004

Pulicatins A−E, Neuroactive Thiazoline Metabolites from Cone Snail-Associated Bacteria ⬇️

scientific article published on October 28, 2010

Purification and Characterization of the Pink-Floyd Drillipeptide, a Bioactive Venom Peptide from Clavus davidgilmouri (Gastropoda: Conoidea: Drilliidae)

scientific article published on 07 August 2020

Purification and characterization of a novel excitatory peptide from Conus distans venom that defines a novel gene superfamily of conotoxins

scientific article published on 5 June 2008

Putative gamma-conotoxins in vermivorous cone snails: the case of Conus delessertii.

scientific article published in January 2005

Rapid expansion of the protein disulfide isomerase gene family facilitates the folding of venom peptides

scientific article published on 8 March 2016

Reagentless Oxidative Folding of Disulfide‐Rich Peptides Catalyzed by an Intramolecular Diselenide ⬇️

scientific article published on March 27, 2012

Reconstructing the Origins of the Somatostatin and Allatostatin-C Signaling Systems Using the Accelerated Evolution of Biodiverse Cone Snail Toxins

scientific article published on 01 April 2022

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

scientific article

Role of hydroxyprolines in the in vitro oxidative folding and biological activity of conotoxins.

scientific article

Selective purification of recombinant neuroactive peptides using the flagellar type III secretion system.

scientific article

Site-specific effects of diselenide bridges on the oxidative folding of a cystine knot peptide, omega-selenoconotoxin GVIA.

scientific article published on March 2010

Small Molecules in the Cone Snail Arsenal

scientific article published on 30 September 2015

Solution conformation of a neuronal nicotinic acetylcholine receptor antagonist alpha-conotoxin OmIA that discriminates alpha3 vs. alpha6 nAChR subtypes

scientific article published on 27 April 2006

Solution conformation of alpha-conotoxin GIC, a novel potent antagonist of alpha3beta2 nicotinic acetylcholine receptors

scientific article published on June 2004

Solution conformation of alphaA-conotoxin EIVA, a potent neuromuscular nicotinic acetylcholine receptor antagonist from Conus ermineus

scientific article

Solution structure of alpha-conotoxin PIA, a novel antagonist of alpha6 subunit containing nicotinic acetylcholine receptors

scientific article

Somatostatin venom analogs evolved by fish-hunting cone snails: From prey capture behavior to identifying drug leads

scientific article published on 25 March 2022

Specialized insulin is used for chemical warfare by fish-hunting cone snails.

scientific article

Specificity, affinity and efficacy of iota-conotoxin RXIA, an agonist of voltage-gated sodium channels Na(V)1.2, 1.6 and 1.7.

scientific article published on 06 April 2008

Stenotrophomonas-Like Bacteria Are Widespread Symbionts in Cone Snail Venom Ducts.

scientific article

Structural Basis for the Inhibition of Voltage-gated Sodium Channels by Conotoxin μO§-GVIIJ.

scientific article published on 27 January 2016

Structural and functional diversities among mu-conotoxins targeting TTX-resistant sodium channels

scientific article published in March 2006

Structural basis for tetrodotoxin-resistant sodium channel binding by mu-conotoxin SmIIIA

scientific article

Structural features of conopeptide genes inferred from partial sequences of the Conus tribblei genome.

scientific article

Structure and Biological Activity of a Turripeptide from Unedogemmula bisaya Venom.

scientific article published in November 2017

Structure and Sodium Channel Activity of an Excitatory I 1 -Superfamily Conotoxin † , ‡

scientific article

Structure and activity of contryphan-Vc2: Importance of the d-amino acid residue.

scientific article published on 16 February 2017

Structure and activity of lobophorins from a turrid mollusk-associated Streptomyces sp ⬇️

scientific article

Structure of a novel P-superfamily spasmodic conotoxin reveals an inhibitory cystine knot motif

scientific article

Structure of the analgesic mu-conotoxin KIIIA and effects on the structure and function of disulfide deletion

scientific article

Structure, dynamics, and selectivity of the sodium channel blocker mu-conotoxin SIIIA.

scientific article

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

scientific article published on 27 August 2007

Subtype-selective conopeptides targeted to nicotinic receptors: Concerted discovery and biomedical applications

scientific article

Synergistic and antagonistic interactions between tetrodotoxin and mu-conotoxin in blocking voltage-gated sodium channels

scientific article

Synthetic muO-conotoxin MrVIB blocks TTX-resistant sodium channel NaV1.8 and has a long-lasting analgesic activity

scientific article published in June 2006

THE INDO-PACIFIC GEMMULA SPECIES IN THE SUBFAMILY TURRINAE: ASPECTS OF FIELD DISTRIBUTION, MOLECULAR PHYLOGENY, RADULAR ANATOMY AND FEEDING ECOLOGY ⬇️

scientific article published on March 5, 2010

The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea.

scientific article

The mitochondrial genome of Conus textile, coxI-coxII intergenic sequences and Conoidean evolution

scientific article

The rescue of developing avian motoneurons from programmed cell death by a selective inhibitor of the fetal muscle-specific nicotinic acetylcholine receptor

scientific article published in June 2008

The tetrodotoxin receptor of voltage-gated sodium channels--perspectives from interactions with micro-conotoxins

scientific article published on 13 July 2010

The three-dimensional structure of an H-superfamily conotoxin reveals a granulin fold arising from a common ICK cysteine framework

scientific article published on 11 April 2019

Total chemical synthesis and NMR characterization of the glycopeptide tx5a, a heavily post-translationally modified conotoxin, reveals that the glycan structure is alpha-D-Gal-(1-->3)-alpha-D-GalNAc

scientific article published in December 2004

Two new 4-Cys conotoxins (framework 14) of the vermivorous snail Conus austini from the Gulf of Mexico with activity in the central nervous system of mice

scientific article

Tyrosine-rich conopeptides affect voltage-gated K+ channels

scientific article

Using Chemistry to Reconstruct Evolution: On the Origins of Fish-Hunting in Venomous Cone Snails

scientific article

Venom Insulins of Cone Snails Diversify Rapidly and Track Prey Taxa

scientific article published on 14 August 2016

gamma -Glutamyl carboxylation: An extracellular posttranslational modification that antedates the divergence of molluscs, arthropods, and chordates

scientific article

muO conotoxins inhibit NaV channels by interfering with their voltage sensors in domain-2.

scientific article

Α- and β-subunit composition of voltage-gated sodium channels investigated with μ-conotoxins and the recently discovered μO§-conotoxin GVIIJ.

scientific article published on 28 January 2015

α-Conotoxin VnIB from Conus ventricosus is a potent and selective antagonist of α6β4* nicotinic acetylcholine receptors

scientific article published on 28 June 2019

α-RgIA, a Novel Conotoxin That Blocks the α9α10 nAChR: Structure and Identification of Key Receptor-Binding Residues

scientific article

αM-Conotoxin MIIIJ Blocks Nicotinic Acetylcholine Receptors at Neuromuscular Junctions of Frog and Fish

scientific article published on 21 March 2020

αS-conotoxin GVIIIB potently and selectively blocks α9α10 nicotinic acetylcholine receptors

scientific article published on 11 June 2015

μ-Conotoxins that differentially block sodium channels NaV1.1 through 1.8 identify those responsible for action potentials in sciatic nerve

scientific article

μ-conotoxin KIIIA derivatives with divergent affinities versus efficacies in blocking voltage-gated sodium channels

scientific article

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