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List of works by Cathy Drennan

3.3-Å resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound

scientific article published on 20 February 2018

A widely distributed diheme enzyme from Burkholderia that displays an atypically stable bis-Fe(IV) state

scientific article published on 07 March 2019

Biochemical and Structural Characterization of a Schiff Base in the Radical-Mediated Biosynthesis of 4-Demethylwyosine by TYW1.

scientific article published on 24 May 2018

Biochemical and crystallographic investigations into isonitrile formation by a non-heme iron-dependent oxidase/decarboxylase

scientific article published on 27 December 2020

Biophysical Examination of the Calcium-Modulated Nickel-Binding Properties of Human Calprotectin Reveals Conformational Change in the EF-Hand Domains and His3Asp Site.

scientific article published on 26 June 2018

Conformational Motions and Water Networks at the α/β Interface in E. coli Ribonucleotide Reductase

scientific article published on 06 July 2020

Crystal Structure of the [4Fe-4S] Cluster-Containing Adenosine-5'-phosphosulfate Reductase from <i>Mycobacterium tuberculosis</i>

scientific article published on 17 May 2021

Crystal Structures of Fumarate Hydratases from Leishmania major in a Complex with Inhibitor 2-Thiomalate

scientific article published on 24 January 2019

Crystal structure of AdoMet radical enzyme 7-carboxy-7-deazaguanine synthase from Escherichia coli suggests how modifications near [4Fe-4S] cluster engender flavodoxin specificity

article

Data publication with the structural biology data grid supports live analysis

scientific article

Disruption of an oligomeric interface prevents allosteric inhibition of Escherichia coli class Ia ribonucleotide reductase.

scientific article published on 26 April 2018

Gated Proton Release during Radical Transfer at the Subunit Interface of Ribonucleotide Reductase

scientific article published on 23 December 2020

Glutamate 52-β at the α/β subunit interface of Escherichia coli class Ia ribonucleotide reductase is essential for conformational gating of radical transfer

scientific article published on 4 April 2017

Molecular basis for catabolism of the abundant metabolite trans-4-hydroxy-L-proline by a microbial glycyl radical enzyme

scientific article published on 17 March 2020

Redox-dependent rearrangements of the NiFeS cluster of carbon monoxide dehydrogenase

scientific article published on 02 October 2018

Ribonucleotide Reductases: Structure, Chemistry, and Metabolism Suggest New Therapeutic Targets

scientific article published on 01 June 2020

Solution structure and biochemical characterization of a spare part protein that restores activity to an oxygen-damaged glycyl radical enzyme

scientific article published on 27 June 2019

Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase from Leishmania major

scientific article published on 27 November 2019

Structural basis for methylphosphonate biosynthesis.

scientific article

Structural basis for non-radical catalysis by TsrM, a radical SAM methylase

scientific article

Structural insight into metallocofactor maturation in carbon monoxide dehydrogenase

scientific article published on 11 July 2019

Structure of a trapped radical transfer pathway within a ribonucleotide reductase holocomplex

scientific article

Structure of human Fe-S assembly subcomplex reveals unexpected cysteine desulfurase architecture and acyl-ACP-ISD11 interactions.

scientific article published on 20 June 2017

Structure-Guided Identification of a Small Molecule That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria

scientific article published on 17 December 2018

X-ray crystallography-based structural elucidation of enzyme-bound intermediates along the 1-deoxy-d-xylulose 5-phosphate synthase reaction coordinate

scientific article published on 25 June 2019

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