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List of works by Christian Wolff

Activity of the anticonvulsant lacosamide in experimental and human epilepsy via selective effects on slow Na+ channel inactivation

scientific article published on 19 November 2016

Brivaracetam differentially affects voltage-gated sodium currents without impairing sustained repetitive firing in neurons

scientific article

Comparative study of lacosamide and classical sodium channel blocking antiepileptic drugs on sodium channel slow inactivation ⬇️

scientific article published on December 13, 2012

Comparative study of membrane potential-sensitive fluorescent probes and their use in ion channel screening assays

scientific article published in October 2003

Current understanding of the mechanism of action of the antiepileptic drug lacosamide.

scientific article

Discovery of a small molecule modulator of the Kv1.1/Kvβ1 channel complex that reduces neuronal excitability and in vitro epileptiform activity

scientific article published on 21 September 2018

Drug binding assays do not reveal specific binding of lacosamide to collapsin response mediator protein 2 (CRMP-2).

scientific article

Functional characterization of the antiepileptic drug candidate, padsevonil, on GABAA receptors

scientific article published on 16 April 2020

GRIN2B gain of function mutations are sensitive to radiprodil, a negative allosteric modulator of GluN2B-containing NMDA receptors

scientific article published on 19 May 2017

Interaction with a lipid membrane: a key step in bacterial toxins virulence.

scientific article

Loss of β1accessory Na+channel subunits causes failure of carbamazepine, but not of lacosamide, in blocking high-frequency firing via differential effects on persistent Na+currents

scientific article published on 27 September 2012

Structure and topology of diphtheria toxin R domain in lipid membranes

scientific article published on 01 January 1999

Synaptic vesicle glycoprotein 2A modulates vesicular release and calcium channel function at peripheral sympathetic synapses

scientific article published on 8 December 2014

The synaptic vesicle glycoprotein 2A ligand levetiracetam inhibits presynaptic Ca2+ channels through an intracellular pathway

scientific article published on May 3, 2012

Towards a KCC2 blocker pharmacophore model ⬇️

scientific article published on April 30, 2012

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