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List of works by Kikuko Hotta

ADIPOQ polymorphisms are associated with insulin resistance in Japanese women

scientific article published on 31 March 2015

Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell

scientific article

Adipocytokine orosomucoid integrates inflammatory and metabolic signals to preserve energy homeostasis by resolving immoderate inflammation

scientific article

Age-Related Adipose Tissue mRNA Expression of ADD1/SREBP1, PPAR , Lipoprotein Lipase, and GLUT4 Glucose Transporter in Rhesus Monkeys

scientific article published on 01 May 1999

Altered expression of carnitine palmitoyltransferase II in liver, muscle, and heart of mouse strain with juvenile visceral steatosis

scientific article published on 01 February 1996

Anomer specificity of glucose-6-phosphatase and glucokinase

scientific article published on 01 December 1986

Association between PPARGC1A polymorphisms and the occurrence of nonalcoholic fatty liver disease (NAFLD).

scientific article

Association between angiotensin II type 1 receptor polymorphisms and the occurrence of nonalcoholic fatty liver disease

scientific article published on 3 March 2009

Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population

scientific article

Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography

scientific article published on 01 March 2012

Association of polymorphisms in GCKR and TRIB1 with nonalcoholic fatty liver disease and metabolic syndrome traits

scientific article published on 01 May 2014

Association of single-nucleotide polymorphisms in MTMR9 gene with obesity

scientific article published on 12 September 2007

Association of variations in the FTO, SCG3 and MTMR9 genes with metabolic syndrome in a Japanese population

article

CDH13 Polymorphisms are Associated with Adiponectin Levels and Metabolic Syndrome Traits Independently of Visceral Fat Mass.

scientific article published in October 2015

Characteristics of Cardiac Hypertrophy in the Juvenile Visceral Steatosis Mouse with Systemic Carnitine Deficiency

scientific article published on 01 April 1998

Characteristics of non-obese non-alcoholic fatty liver disease: Effect of genetic and environmental factors

scientific article published on 05 April 2016

Computed tomography analysis of the association between the SH2B1 rs7498665 single-nucleotide polymorphism and visceral fat area

article

Disordered expression of glycolytic and gluconeogenic liver enzymes of juvenile visceral steatosis mice with systemic carnitine deficiency

scientific article published on 01 May 1996

Disordered expression of hepatic glycolytic and gluconeogenic enzymes in Itsuka long-evans Tokushima fatty rats with spontaneous long-term hyperglycemia

scientific article published on 01 February 1996

Effects of FTO Genotype on Weight Loss and Metabolic Risk Factors in Response to Calorie Restriction Among Japanese Women ⬇️

scientific article published on October 20, 2011

Enhancement of the Aquaporin Adipose Gene Expression by a Peroxisome Proliferator-activated Receptor γ ⬇️

scientific article published on October 25, 2001

FTO gene variant and risk of hypertension: A meta-analysis of 57,464 hypertensive cases and 41,256 controls

article

Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity

scientific article

Gene expression profiling of non-alcoholic steatohepatitis using gene set enrichment analysis

article

Genetic variations in the CYP17A1 and NT5C2 genes are associated with a reduction in visceral and subcutaneous fat areas in Japanese women.

scientific article

Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan.

scientific article

Genomic structure and mutations in adipose-specific gene, adiponectin

article

INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese.

scientific article published on 10 July 2008

Identification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling

scientific article

Identification of core gene networks and hub genes associated with progression of non-alcoholic fatty liver disease by RNA sequencing.

scientific article published on 20 February 2017

Identification of differentially methylated region (DMR) networks associated with progression of nonalcoholic fatty liver disease

scientific article published in Scientific Reports

Identification of the genomic region under epigenetic regulation during non-alcoholic fatty liver disease progression.

scientific article

Influence of inducible nitric oxide synthase polymorphisms in Japanese patients with non-alcoholic fatty liver disease

scientific article published on 13 July 2009

Influence of the rs738409 polymorphism in patatin-like phospholipase 3 on the treatment efficacy of non-alcoholic fatty liver disease with type 2 diabetes mellitus.

scientific article

Life style-related diseases of the digestive system: gene expression in nonalcoholic steatohepatitis patients and treatment strategies.

scientific article published on 06 October 2007

Monkey Leptin Receptor mRNA: Sequence, Tissue Distribution, and mRNA Expression in the Adipose Tissue of Normal, Hyperinsulinemic, and Type 2 Diabetic Rhesus Monkeys ⬇️

scientific article published on September 1, 1998

Mutation in bombesin receptor subtype-3 gene is not a major cause of obesity in the Japanese

article

NUDT3 rs206936 is associated with body mass index in obese Japanese women

scientific article published on 25 May 2013

New insights about obesity-related genes

scientific article published in February 2009

Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin

scientific article

Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. 1999.

scientific article published in August 2012

Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients

scientific article

Polymorphisms in NRXN3, TFAP2B, MSRA, LYPLAL1, FTO and MC4R and their effect on visceral fat area in the Japanese population.

scientific article published on 12 August 2010

Rat-liver-type phosphofructokinase mRNA. Structure, tissue distribution and regulation ⬇️

scientific article published on December 5, 1991

Relationships of PPARγ and PPARγ2 mRNA levels to obesity, diabetes and hyperinsulinaemia in rhesus monkeys

scientific article published on 01 October 1998

Screening of 336 single-nucleotide polymorphisms in 85 obesity-related genes revealed McKusick-Kaufman syndrome gene variants are associated with metabolic syndrome.

scientific article published on 27 February 2009

Secretogranin II binds to secretogranin III and forms secretory granules with orexin, neuropeptide Y, and POMC.

scientific article

Serum ferritin is a clinical biomarker in Japanese patients with nonalcoholic steatohepatitis (NASH) independent of HFE gene mutation

scientific article published on 7 March 2009

Serum vaspin concentrations are closely related to insulin resistance, and rs77060950 at SERPINA12 genetically defines distinct group with higher serum levels in Japanese population.

scientific article

Small Heterodimer Partner, an Orphan Nuclear Receptor, Augments Peroxisome Proliferator-activated Receptor γ Transactivation ⬇️

scientific article (publication date: 11 January 2002)

Structure of the entire human muscle phosphofructokinase-encoding gene: a two-promoter system ⬇️

scientific article published on August 15, 1991

Targeted next-generation sequencing and fine linkage disequilibrium mapping reveals association of PNPLA3 and PARVB with the severity of nonalcoholic fatty liver disease

scientific article published on 13 March 2014

Targeted-bisulfite sequence analysis of the methylation of CpG islands in genes encoding PNPLA3, SAMM50, and PARVB of patients with non-alcoholic fatty liver disease.

scientific article published on 14 March 2015

The FTO genotype as a useful predictor of body weight maintenance: initial data from a 5-year follow-up study

scientific article

The expression of SPARC in adipose tissue and its increased plasma concentration in patients with coronary artery disease.

scientific article published in July 2001

Thiazolidinedione derivative improves fat distribution and multiple risk factors in subjects with visceral fat accumulation—double-blind placebo-controlled trial ⬇️

scientific article published on December 1, 2001

Visceral fat is a major contributor for multiple risk factor clustering in Japanese men with impaired glucose tolerance.

scientific article published in December 2001

[Genetic testing and gene-based testing for obesity]

scientific article published on 01 December 2005

[Molecular mechanism in the development of the complications associated with obesity--the physiological and pathological role of adipocytokines]

scientific article published on 01 March 2001

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