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List of works by Christian Rainer Wirtz

10th annual congress of the German Society for Radiation Oncology

scientific article published in June 2004

3D ultrasound navigation in syrinx surgery - a feasibility study

scientific article

A conceptually new treatment approach for relapsed glioblastoma: coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care

scientific article

A deformable digital brain atlas system according to Talairach and Tournoux.

scientific article published on March 2004

A flexible registration framework for multimodal image data

scientific article

Activation of Cytotoxic Natural Killer Cells After Aneurysmal Subarachnoid Hemorrhage

scientific article published on 16 March 2017

An integrated head-holder/coil for intraoperative MRI in open neurosurgery

scientific article published on 01 May 2000

Anti-glioma Activity of Dapsone and Its Enhancement by Synthetic Chemical Modification

scientific article published on 29 August 2017

Application of a novel FAM-conjugated activity-based probe to determine cathepsin G activity intracellularly

scientific article published on 23 October 2019

Artesunate enhances the antiproliferative effect of temozolomide on U87MG and A172 glioblastoma cell lines

scientific article published on February 2014

Augmented reality-assisted ventriculostomy

scientific article published on 01 January 2021

Bcl-2/Bcl-xL inhibition predominantly synergistically enhances the anti-neoplastic activity of a low-dose CUSP9 repurposed drug regime against glioblastoma

scientific article published on 30 July 2019

Biopsy findings of symptomatic cerebral X-linked adrenoleucodystrophy and histological differentiation from multiple sclerosis

scientific article published in August 2014

Bortezomib primes glioblastoma, including glioblastoma stem cells, for TRAIL by increasing tBid stability and mitochondrial apoptosis

scientific article

Brain metastases in gastrointestinal cancers: is there a role for surgery?

scientific article

Brain metastasis in pancreatic cancer

scientific article published on 19 February 2013

CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells

scientific article

Cancer stem cells: The potential role of autophagy, proteolysis, and cathepsins in glioblastoma stem cells

scientific article published on March 2017

Cathepsin G-mediated proteolytic degradation of MHC class I molecules to facilitate immune detection of human glioblastoma cells

scientific article published on 2 February 2016

Cell surface cathepsin G activity differs between human natural killer cell subsets.

scientific article

Cerebral vasospasm and health-related quality of life after subarachnoid hemorrhage.

scientific article published on 25 September 2012

Clinical evaluation and follow-up results for intraoperative magnetic resonance imaging in neurosurgery.

scientific article

Clinical outcome after decompression of intraneural peroneal ganglion cyst and its morphologic correlation to postoperative nerve ultrasound

scientific article published on 28 June 2019

Clipping as re-treatment strategy after treatment of a cerebral aneurysm with the Woven EndoBridge embolization device: case report

scientific article published on 01 March 2018

Cognitive performance following spontaneous subarachnoid haemorrhage versus other forms of intracranial haemorrhage.

scientific article published on 24 July 2013

Combined inhibition of HER1/EGFR and RAC1 results in a synergistic antiproliferative effect on established and primary cultured human glioblastoma cells

scientific article published on 5 July 2013

Combined inhibition of RAC1 and Bcl-2/Bcl-xL synergistically induces glioblastoma cell death through down-regulation of the Usp9X/Mcl-1 axis

scientific article published on 11 March 2019

Comment on: "ependymal cyst in the conus medullaris"

scientific article published on 01 December 2010

Comparative study of application accuracy of two frameless neuronavigation systems: experimental error assessment quantifying registration methods and clinically influencing factors

scientific article

Comparison of hemispheric dominance and correlation of evoked speech responses between functional magnetic resonance imaging and navigated transcranial magnetic stimulation in language mapping

scientific article published on 25 September 2018

Comparison of intraoperative MR imaging and 3D-navigated ultrasonography in the detection and resection control of lesions

scientific article

Contemporary use of intraoperative imaging in glioma surgery: A survey among EANS members.

scientific article published on 31 October 2017

Counseling Patients with a Glioblastoma Amenable Only for Subtotal Resection: Results of a Multicenter Retrospective Assessment of Survival and Neurologic Outcome.

scientific article

Current state and future perspective of drug repurposing in malignant glioma

scientific article published on 14 November 2019

DeepSeg: deep neural network framework for automatic brain tumor segmentation using magnetic resonance FLAIR images

scientific article published on 05 May 2020

Desmopressin acetate in intracranial haemorrhage

scientific article published on 23 December 2014

Determining the utility of intraoperative magnetic resonance imaging for transsphenoidal surgery: a retrospective study

scientific article published on 13 December 2013

Diagnostic accuracy of intraoperative perfusion-weighted MRI and 5-aminolevulinic acid in relation to contrast-enhanced intraoperative MRI and 11C-methionine positron emission tomography in resection of glioblastoma: a prospective study

scientific article published on 28 May 2018

Do Complication Rates of Ventricular Drain Placement Differ between Twist Drill and Burr Hole in Acute Hydrocephalus?

scientific article published on 24 April 2019

Does the routine use of intraoperative MRI prolong progression free survival in low-grade glioma surgery? A retrospective study

Drug combinations enhancing the antineoplastic effects of erlotinib in high-grade glioma

scientific article published on September 2011

Dual metabolic reprogramming by ONC201/TIC10 and 2-Deoxyglucose induces energy depletion and synergistic anti-cancer activity in glioblastoma

scientific article published on 02 March 2020

EXTH-54. Bcl-2/Bcl-xL INHIBITION SYNERGISTICALLY ENHANCES THE ANTI-NEOPLASTIC ACTIVITY OF CUSP9 AGAINST GLIOBLASTOMA CELLS IN VITRO

EXTH-55. CONCOMITANT INHIBITION OF RAC1 AND Bcl-2/Bcl-xL INTERFERES WITH THE Mcl-1/Usp9X AXIS AND YIELDS SYNERGISTIC ANTI-GLIOMA ACTIVITY

Epidermal growth factor receptor inhibition for the treatment of glioblastoma multiforme and other malignant brain tumours

scientific article

Epidermal to Mesenchymal Transition and Failure of EGFR-Targeted Therapy in Glioblastoma

scientific article published on 08 May 2012

Erlotinib in glioblastoma: lost in translation?

scientific article published on October 2011

Evaluating patients for psychosocial distress and supportive care needs based on health-related quality of life in primary brain tumors: a prospective multicenter analysis of patients with gliomas in an outpatient setting

scientific article published on 16 September 2016

Evaluation of surgical decision making and resulting outcome in patients with highly eloquent glioblastoma: Results of a multicenter assessment

scientific article published on 8 September 2017

Exogenous cathepsin G upregulates cell surface MHC class I molecules on immune and glioblastoma cells

scientific article published on 28 October 2016

Experimental study of sector and linear array ultrasound accuracy and the influence of navigated 3D-reconstruction as compared to MRI in a brain tumor model

scientific article

First Report of Recurrent Intramuscular Lipoma after Decompression Surgery of the Lumbar Spine

scientific article published on 27 April 2015

Fluorescence guided surgery by 5-ALA and intraoperative MRI in high grade glioma: a systematic review

scientific article published on 28 November 2018

Gravitational valves. Personal 27 year experience in 420 patients

HOXA7, HOXA9, and HOXA10 are differentially expressed in clival and sacral chordomas

scientific article

Head Injury in Children: Has a Change in Circumstances Caused an Increase in Treatment Numbers?

scientific article published on 4 November 2014

Health-related quality of life after spontaneous subarachnoid hemorrhage measured in a recent patient population

scientific article published on 6 October 2012

Health-related quality of life and distress in elderly vs. younger patients with high-grade glioma-results of a multicenter study

scientific article published on 14 February 2020

Hemicraniectomy with dural augmentation in medically uncontrollable hemispheric infarction

scientific article published on 01 May 1997

High-resolution laser surface scanning for patient registration in cranial computer-assisted surgery.

scientific article

Histopathological Insights on Imaging Results of Intraoperative Magnetic Resonance Imaging, 5-Aminolevulinic Acid, and Intraoperative Ultrasound in Glioblastoma Surgery.

scientific article

Image guided aneurysm surgery in a Brainsuite® ioMRI Miyabi 1.5 T environment

scientific article

Image guided excision of a ruptured feeding artery "pedicle aneurysm" associated with an arteriovenous malformation in a child: case report

scientific article published on 01 January 1997

Image-guided neurosurgery with intraoperative MRI: update of frameless stereotaxy and radicality control

scientific article published in January 1997

Immune phenotypes predict survival in patients with glioblastoma multiforme.

scientific article

Impact of extent of resection and recurrent surgery on clinical outcome and overall survival in a consecutive series of 170 patients for glioblastoma in intraoperative high field magnetic resonance imaging.

scientific article

Inhibition of NF-κB signaling ablates the invasive phenotype of glioblastoma

scientific article published on 21 October 2013

Initial experience with an ultrasound-integrated single-RACK neuronavigation system.

scientific article published on November 2001

Interventional MRI-guided brain biopsies using inductively coupled surface coils

scientific article published on 01 February 2000

Intraneural hemangioma of the ulnar nerve

scientific article

Intraoperative MR imaging increases the extent of tumor resection in patients with high-grade gliomas.

scientific article published in October 1999

Intraoperative MRI for interventional neurosurgical procedures and tumor resection control in children

scientific article published in February 2006

Intraoperative MRI in transsphenoidal resection of invasive pituitary macroadenomas

scientific article published on 04 April 2019

Intraoperative computer-assisted neuronavigation in functional neurosurgery

scientific article published on 01 January 1996

Intraoperative diagnostic and interventional magnetic resonance imaging in neurosurgery.

scientific article published on May 1997

Intraoperative guidance in maxillofacial and craniofacial surgery

scientific article published on 01 January 1997

Intraoperative high-resolution ultrasound and contrast-enhanced ultrasound of peripheral nerve tumors and tumorlike lesions

scientific article published in September 2015

Intraoperative high-resolution ultrasound: a new technique in the management of peripheral nerve disorders

scientific article published on 05 November 2010

Intraoperative magnetic resonance imaging to update interactive navigation in neurosurgery: method and preliminary experience

scientific article published on January 1997

Intrathecal baclofen treatment for stiff-man syndrome: pump failure may be fatal

scientific article published on 01 November 1994

Is MGMT promoter methylation to be considered in the decision making for recurrent surgery in glioblastoma patients?

scientific article published on 5 February 2018

Is There an Indication for Intraoperative MRI in Subtotal Resection of Glioblastoma? A Multicenter Retrospective Comparative Analysis.

scientific article

Lactoferrin Is an Allosteric Enhancer of the Proteolytic Activity of Cathepsin G.

scientific article

Linear array ultrasound in low-grade glioma surgery: histology-based assessment of accuracy in comparison to conventional intraoperative ultrasound and intraoperative MRI.

scientific article published on 6 January 2015

Low-field interventional MRI in neurosurgery: finding the right dose of contrast medium

scientific article published in March 2001

Low-grade Glioma Surgery in Intraoperative Magnetic Resonance Imaging: Results of a Multicenter Retrospective Assessment of the German Study Group for Intraoperative Magnetic Resonance Imaging.

scientific article published on 28 October 2015

Lows and highs: 15 years of development in intraoperative magnetic resonance imaging.

scientific article

Mechanisms, treatment, and patient outcome of iatrogenic injury to the brachial plexus - a retrospective single-center study

scientific article

Modified Headholder and operating table for intra-operative MRI in neurosurgery

scientific article published on 01 October 1998

Monocrystalline iron oxide nanoparticles: possible solution to the problem of surgically induced intracranial contrast enhancement in intraoperative MR imaging.

scientific article published in January 2001

Multicentric Registry Study on Epidemiological and Biological Disease Profile as Well as Clinical Outcome in Patients with Low-Grade Gliomas: The LoG-Glio Project

scientific article published on 24 September 2019

Multimodal Online Monitoring in Middle Cerebral Artery Territory Stroke ⬇️

scientific article published on November 1, 2001

Navigated high frequency ultrasound: description of technique and clinical comparison with conventional intracranial ultrasound.

scientific article published on 27 May 2014

Neurolymphomatosis : Two case reports

scientific article published on 27 November 2017

Neuronavigation--first experiences with three different commercially available systems.

scientific article

Neuronavigation. Methods and prospects

scientific article

Olanzapine inhibits proliferation, migration and anchorage-independent growth in human glioblastoma cell lines and enhances temozolomide's antiproliferative effect

scientific article published on 19 December 2014

Outcome After Decompressive Craniectomy in Different Pathologies

scientific article published on 25 June 2016

Pre- and intraoperative processing and integration of various anatomical and functional data in neurosurgery

scientific article

Preoperative planning and intraoperative navigation in skull base surgery

scientific article published on 01 August 1998

Quality of Life After Treatment of Unruptured Intracranial Aneurysms

scientific article published on 20 September 2018

Response to Cervical Medial Branch Blocks In Patients with Cervicogenic Vertigo

Ribozyme-mediated inhibition of 801-bp deletion-mutant epidermal growth factor receptor mRNA expression in glioblastoma multiforme.

scientific article published on 30 June 2010

Robot-assisted craniotomy

scientific article published in June 2005

Sensitivity and specificity of linear array intraoperative ultrasound in glioblastoma surgery: a comparative study with high field intraoperative MRI and conventional sector array ultrasound

scientific article published on 10 April 2015

Simultaneous Interference with HER1/EGFR and RAC1 Signaling Drives Cytostasis and Suppression of Survivin in Human Glioma Cells in Vitro.

scientific article

Sodium Fluorescein as Intraoperative Visualization Tool During Peripheral Nerve Biopsies

Sodium Fluorescein-Guided Surgery in Peripheral Nerve Sheath Tumors: First Experience in 10 Cases of Schwannoma

scientific article published on 17 January 2019

Super-selective cervical nerve root stimulation in contralateral C7 transfer: An intraoperative study

scientific article published on 7 October 2017

Supportive Care Needs in Glioma Patients and Their Caregivers in Clinical Practice: Results of a Multicenter Cross-Sectional Study

Surgery for Diffuse WHO Grade II Gliomas: Volumetric Analysis of a Multicenter Retrospective Cohort From the German Study Group for Intraoperative Magnetic Resonance Imaging

scientific article published on 01 January 2020

Surgery for Glioblastoma: Impact of the Combined Use of 5-Aminolevulinic Acid and Intraoperative MRI on Extent of Resection and Survival

scientific article published on 26 June 2015

Surgical Workflow Analysis: Ideal Application of Navigated Linear Array Ultrasound in Low-Grade Glioma Surgery.

scientific article

Surgically induced intracranial contrast enhancement: potential source of diagnostic error in intraoperative MR imaging.

scientific article

Ten years' experience with intraoperative MRI-assisted transsphenoidal pituitary surgery

scientific article published on 01 June 2020

The Value of Intraoperative Magnetic Resonance Imaging in Endoscopic and Microsurgical Transsphenoidal Pituitary Adenoma Resection.

scientific article

The Value of Intraoperative and Early Postoperative Magnetic Resonance Imaging in Low-Grade Glioma Surgery: A Retrospective Study.

scientific article published on 8 June 2016

The benefit of neuronavigation for neurosurgery analyzed by its impact on glioblastoma surgery.

scientific article published in June 2000

The evolution of invasive cerebral vasospasm treatment in patients with spontaneous subarachnoid hemorrhage and delayed cerebral ischemia-continuous selective intracarotid nimodipine therapy in awake patients without sedation

scientific article published on 26 May 2018

The influence of nimodipine and vasopressors on outcome in patients with delayed cerebral ischemia after spontaneous subarachnoid hemorrhage

scientific article published on 08 March 2019

The patients' view: impact of the extent of resection, intraoperative imaging, and awake surgery on health-related quality of life in high-grade glioma patients-results of a multicenter cross-sectional study.

scientific article published on 6 March 2017

The rationale of targeting neutrophils with dapsone during glioblastoma treatment

scientific article published on October 2011

Therapy for Recurrent High-Grade Gliomas: Results of a Prospective Multicenter Study on Health-Related Quality of Life

scientific article published on 10 March 2017

To treat or not to treat? A retrospective multicenter assessment of survival in patients with IDH-mutant low-grade glioma based on adjuvant treatment

scientific article published on 19 July 2019

Treatment of trigeminal neuralgia associated with multiple sclerosis: case report

scientific article published on 01 November 2004

Tumor detection with 5-aminolevulinic acid fluorescence and Gd-DTPA-enhanced intraoperative MRI at the border of contrast-enhancing lesions: a prospective study based on histopathological assessment.

scientific article

Vacquinol-1 inducible cell death in glioblastoma multiforme is counter regulated by TRPM7 activity induced by exogenous ATP.

scientific article

Value of whole-body low-dose computed tomography in patients with ventriculoperitoneal shunts: a retrospective study.

scientific article published on 5 January 2018

Viability of glioblastoma stem cells is effectively reduced by diisothiocyanate-derived mercapturic acids

scientific article published on 21 August 2018

Which clinical variable influences health-related quality of life the most after spontaneous subarachnoid hemorrhage? Hunt and Hess scale, Fisher score, World Federation of Neurosurgeons score, Brussels coma score, and Glasgow coma score compared

scientific article published on 25 September 2012

[A computer system for planning and carrying out neurosurgical interventions]

scientific article published on 01 January 2002

[Comment on the contribution by C. B. Ostertag and P. C. Warnke. Neuronavigation. Computer-assisted neurosurgery]

scientific article published on 01 February 2000

[Intraoperative magnetic resonance imaging. Fifteen years' experience in the neurosurgical hybrid operating suite].

scientific article

[Intraoperative magnetic resonance tomography for control of extent of neurosurgical operations]

scientific article published in March 1998

[Quantification of brain shift effects in MRI images]

scientific article published on 01 January 1997

[The hybrid operating room. Home of high-end intraoperative imaging]

scientific article published on 01 February 2012

[Virtual reality in neurosurgery]

scientific article published on 01 March 2000

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