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List of works by Lisbeth A Guethlein

A Distinctive Cytoplasmic Tail Contributes to Low Surface Expression and Intracellular Retention of the Patr-AL MHC Class I Molecule

scientific article

A subpopulation of human peripheral blood NK cells that lacks inhibitory receptors for self-MHC is developmentally immature

scientific article published on 28 March 2007

Adaptive Natural Killer Cell and Killer Cell Immunoglobulin-Like Receptor-Expressing T Cell Responses are Induced by Cytomegalovirus and Are Associated with Protection against Cytomegalovirus Reactivation after Allogeneic Donor Hematopoietic Cell Tr

scientific article

Allele-level haplotype frequencies and pairwise linkage disequilibrium for 14 KIR loci in 506 European-American individuals

scientific article

Allelic polymorphism synergizes with variable gene content to individualize human KIR genotype

scientific article (publication date: March 2002)

Although divergent in residues of the peptide binding site, conserved chimpanzee Patr-AL and polymorphic human HLA-A*02 have overlapping peptide-binding repertoires

scientific article (publication date: February 2011)

Bonobos Maintain Immune System Diversity with Three Functional Types of MHC-B.

scientific article published on 27 March 2017

Characterization of killer immunoglobulin-like receptor genetics and comprehensive genotyping by pyrosequencing in rhesus macaques

scientific article

Chimpanzee susceptibility to hepatitis C virus infection correlates with presence of Pt-KIR3DS2 and Pt-KIR2DL9: paired activating and inhibitory natural killer cell receptors

scientific article

Class I HLA haplotypes form two schools that educate NK cells in different ways

scientific article published on 09 September 2016

Co-evolution of Human Leukocyte Antigen (HLA) Class I Ligands with Killer-Cell Immunoglobulin-Like Receptors (KIR) in a Genetically Diverse Population of Sub-Saharan Africans

scientific article (publication date: October 2013)

Co-evolution of MHC class I and variable NK cell receptors in placental mammals

scientific article published on September 2015

Coevolution of killer cell Ig-like receptors with HLA-C to become the major variable regulators of human NK cells

scientific article (publication date: October 2010)

Comparison of Chimpanzee and Human Leukocyte Ig-Like Receptor Genes Reveals Framework and Rapidly Evolving Genes ⬇️

scientific article published on November 15, 2001

Complex MHC Class I Gene Transcription Profiles and Their Functional Impact in Orangutans

scientific article published on 18 December 2015

Conservation and Variation in Human and Common Chimpanzee CD94 and NKG2 Genes ⬇️

scientific article published on January 1, 2002

Conservation, Extensive Heterozygosity, and Convergence of Signaling Potential All Indicate a Critical Role for KIR3DL3 in Higher Primates

scientific article published on 28 January 2019

Correction to: Nomenclature report 2019: major histocompatibility complex genes and alleles of great and small ape and old and new world monkey species

scientific article published on 01 February 2020

Defining KIR and HLA Class I Genotypes at Highest Resolution via High-Throughput Sequencing.

scientific article published on August 2016

Definition of the cattle killer cell Ig-like receptor gene family: comparison with aurochs and human counterparts

scientific article

Description of the novelKIR2DL4*035allele identified using high-throughput sequencing

scientific article published on 24 February 2016

Different NK cell surface phenotypes defined by the DX9 antibody are due to KIR3DL1 gene polymorphism

scientific article (publication date: March 2001)

Different patterns of evolution in the centromeric and telomeric regions of group A and B haplotypes of the human killer cell Ig-like receptor locus

scientific article (publication date: 29 December 2010)

Dimorphic motifs in D0 and D1+D2 domains of killer cell Ig-like receptor 3DL1 combine to form receptors with high, moderate, and no avidity for the complex of a peptide derived from HIV and HLA-A*2402.

scientific article

Distinguishing functional polymorphism from random variation in the sequences of >10,000 HLA-A, -B and -C alleles

scientific article published on 26 June 2017

Diversity of KIR, HLA Class I, and Their Interactions in Seven Populations of Sub-Saharan Africans

scientific article published on 27 March 2019

Donor KIR B Genotype Improves Progression-Free Survival of Non-Hodgkin Lymphoma Patients Receiving Unrelated Donor Transplantation

scientific article published on 21 May 2016

Donor Killer Cell Immunoglobulin-Like Receptor Genotype Does Not Improve Graft-versus-Leukemia Responses in Chronic Lymphocytic Leukemia after Unrelated Donor Transplant: A Center for International Blood and Marrow Transplant Research Analysis

scientific article published on 27 December 2018

Donor killer cell Ig-like receptor B haplotypes, recipient HLA-C1, and HLA-C mismatch enhance the clinical benefit of unrelated transplantation for acute myelogenous leukemia

scientific article

Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia

scientific article

Donor-recipient combinations of group A and B KIR haplotypes and HLA class I ligand affect the outcome of HLA-matched, sibling donor hematopoietic cell transplantation

scientific article published on 12 March 2007

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia

scientific article

Evolution and survival of marine carnivores did not require a diversity of killer cell Ig-like receptors or Ly49 NK cell receptors

scientific article published on March 2009

Evolution of killer cell Ig-like receptor (KIR) genes: definition of an orangutan KIR haplotype reveals expansion of lineage III KIR associated with the emergence of MHC-C.

scientific article published in July 2007

Genetic and environmental determinants of human NK cell diversity revealed by mass cytometry

scientific article published on October 2013

Genetic control of human NK cell repertoire

scientific article published on 01 July 2002

Genetics of Natural Killer Cells in Human Health, Disease, and Survival

scientific article published on 2 February 2018

Genotype List String: a grammar for describing HLA and KIR genotyping results in a text string

scientific article published on August 2013

HLA class I variation in Iranian Lur and Kurd populations: high haplotype and allotype diversity with an abundance of KIR ligands.

scientific article published on 24 August 2016

Hematopoietic stem cell transplantation: Improving alloreactive Bw4 donor selection by genotyping codon 86 of KIR3DL1/S1.

scientific article published on 18 March 2016

Human KIR sequences 2003.

scientific article published on 28 June 2003

Human NK Cells Downregulate Zap70 and Syk in Response to Prolonged Activation or DNA Damage

scientific article published on 20 December 2017

Human-specific evolution and adaptation led to major qualitative differences in the variable receptors of human and chimpanzee natural killer cells

scientific article

Human-specific evolution of killer cell immunoglobulin-like receptor recognition of major histocompatibility complex class I molecules

scientific article published on March 2012

Humans Differ from Other Hominids in Lacking an Activating NK Cell Receptor That Recognizes the C1 Epitope of MHC Class I ⬇️

scientific article published on August 27, 2010

IPD-MHC 2.0: an improved inter-species database for the study of the major histocompatibility complex

scientific article (publication date: 4 January 2017)

In vitro education of human natural killer cells by KIR3DL1

scientific article published on 13 November 2019

KIR B donors improve the outcome for AML patients given reduced intensity conditioning and unrelated donor transplantation

scientific article published on 01 February 2020

KIR Donor Selection: Feasibility in Identifying better Donors

scientific article published on 24 August 2018

KIR Variation in Iranians Combines High Haplotype and Allotype Diversity With an Abundance of Functional Inhibitory Receptors

scientific article published on 02 April 2020

KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A * 11 while diminishing avidity for HLA-C

scientific article

KIR2DS5 allotypes that recognize the C2 epitope of HLA-C are common among Africans and absent from Europeans

scientific article published on 6 July 2017

Killer-cell immunoglobulin-like receptor (KIR) nomenclature report, 2002

scientific article published on 01 June 2003

Killer-cell immunoglobulin-like receptor (KIR) nomenclature report, 2002.

scientific article published in July 2003

Killer-cell immunoglobulin-like receptor (KIR) nomenclature report, 2002.

scientific article published in June 2003

Killer-cell immunoglobulin-like receptor (KIR) nomenclature report, 2002.

scientific article published on 28 June 2003

Linkage of Patr-AL to Patr-A and- B in the major histocompatibility complex of the common chimpanzee (Pan troglodytes).

scientific article published on 11 April 2002

Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population

scientific article published on 20 August 2015

Meiotic recombination generates rich diversity in NK cell receptor genes, alleles, and haplotypes.

scientific article (publication date: May 2009)

Missing KIR ligands are associated with less relapse and increased graft-versus-host disease (GVHD) following unrelated donor allogeneic HCT.

scientific article published on 22 February 2007

Modes of salmonid MHC class I and II evolution differ from the primate paradigm

scientific article published in March 2001

Mutation at positively selected positions in the binding site for HLA-C shows that KIR2DL1 is a more refined but less adaptable NK cell receptor than KIR2DL3.

scientific article

NK cell receptors of the orangutan (Pongo pygmaeus): a pivotal species for tracking the coevolution of killer cell Ig-like receptors with MHC-C.

scientific article

Natural selection on marine carnivores elaborated a diverse family of classical MHC class I genes exhibiting haplotypic gene content variation and allelic polymorphism

scientific article

Natural variation at position 45 in the D1 domain of lineage III killer cell immunoglobulin-like receptors (KIR) has major effects on the avidity and specificity for MHC class I ⬇️

scientific article published on 04 May 2011

New DP sequences: three DPA1 and one DPB1.

scientific article published in May 1993

Nomenclature for the KIR of non-human species

scientific article published on 04 June 2018

Nomenclature report 2019: major histocompatibility complex genes and alleles of Great and Small Ape and Old and New World monkey species

scientific article published on 17 October 2019

Nomenclature report for killer-cell immunoglobulin-like receptors (KIR) in macaque species: new genes/alleles, renaming recombinant entities and IPD-NHKIR updates

scientific article published on 29 November 2019

Polymorphic HLA-C Receptors Balance the Functional Characteristics of KIR Haplotypes

scientific article

Polymorphic sites away from the Bw4 epitope that affect interaction of Bw4+ HLA-B with KIR3DL1

scientific article

Predominance of group A KIR haplotypes in Japanese associated with diverse NK cell repertoires of KIR expression

scientific article published on 24 October 2002

Pregnancy immunogenetics: NK cell education in the womb? ⬇️

scientific article published on October 25, 2010

Primate-specific regulation of natural killer cells.

scientific article

Re-evaluation of DRB1*0702: evidence for only one allele, DRB1*0701, encoding the beta chain of the HLA-DR7 antigen

scientific article published on February 1994

Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation

scientific article published on 28 September 2015

Regulation of the expression of mouse TAP-associated glycoprotein (tapasin) by cytokines

scientific article published on 01 October 2002

Resurrecting KIR2DP1: A Key Intermediate in the Evolution of Human Inhibitory NK Cell Receptors That Recognize HLA-C.

scientific article

Review: Immunogenetics of human placentation

scientific article published on 15 December 2011

Rhesus macaque KIR bind human MHC class I with broad specificity and recognize HLA-C more effectively than HLA-A and HLA-B

scientific article published on 26 May 2011

Sequences of 95 human MHC haplotypes reveal extreme coding variation in genes other than highly polymorphic HLA class I and II.

scientific article published on 30 March 2017

Short KIR haplotypes in pygmy chimpanzee (Bonobo) resemble the conserved framework of diverse human KIR haplotypes

scientific article

Signature Patterns of MHC Diversity in Three Gombe Communities of Wild Chimpanzees Reflect Fitness in Reproduction and Immune Defense against SIVcpz

scientific article (publication date: May 2015)

The Intergenic Recombinant HLA-B∗46:01 Has a Distinctive Peptidome that Includes KIR2DL3 Ligands

scientific article published on May 2017

The expanded cattle KIR genes are orthologous to the conserved single-copy KIR3DX1 gene of primates

scientific article published on 21 April 2007

The production of KIR-Fc fusion proteins and their use in a multiplex HLA class I binding assay

scientific article

The shaping of modern human immune systems by multiregional admixture with archaic humans

scientific article

Transient receptor potential TRPM3 channels: Pharmacology, signaling, and biological functions

scientific article

Two Orangutan Species Have Evolved Different KIR Alleles and Haplotypes.

scientific article published on 6 March 2017

Two alternate strategies for innate immunity to Epstein-Barr virus: One using NK cells and the other NK cells and γδ T cells.

scientific article published on 3 May 2017

Two to Tango: Co-evolution of Hominid Natural Killer Cell Receptors and MHC

Variable NK cell receptors exemplified by human KIR3DL1/S1

scientific article published on July 2011

Very long haplotype tracts characterized at high resolution from HLA homozygous cell lines

scientific article

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