List of works - Inmaculada Robina

6-Azido hyacinthacine A2 gives a straightforward access to the first multivalent pyrrolizidine architectures

scientific article published in August 2014

A D-ribofuranosylamine as glycosyl acceptor

scientific article published on 01 May 1994

Allenyl sulfones and allenyl sulfides in the synthesis of 3-pyrrolines. A novel nucleophilic [3 + 2] cycloaddition on allenyl sulfones giving rearranged cycloadducts

scientific article published on 01 November 2009

An efficient combinatorial method for the discovery of glycosidase inhibitors

scientific article published on 01 May 2002

Azabicyclic vinyl sulfones for residue-specific dual protein labelling

scientific article published on 18 March 2019

Derivatives of (2R,3R,4S)-2-aminomethylpyrrolidine-3,4-diol are selective alpha-mannosidase inhibitors.

scientific article

Differential modulation of SIRT6 deacetylase and deacylase activities by lysine-based small molecules

scientific article published on 25 June 2019

Discovery of a Potent α-Galactosidase Inhibitor by in Situ Analysis of a Library of Pyrrolizidine-(Thio)urea Hybrid Molecules Generated via Click Chemistry

scientific article published on 01 August 2018

Effects of Ethylene Glycol Addition on the Aggregation and Micellar Growth of Gemini Surfactants

article

Epididymal α-l-fucosidase and its possible role in remodelling the surface of bull spermatozoa

scientific article published on 19 August 2017

Expanding the library of divalent fucosidase inhibitors with polyamino and triazole-benzyl bridged bispyrrolidines

scientific article

Exploiting the ring strain in bicyclo[2.2.1]heptane systems for the stereoselective preparation of highly functionalized cyclopentene, dihydrofuran, pyrroline, and pyrrolidine scaffolds

scientific article published on 08 November 2011

Exploring a Multivalent Approach to α-L-Fucosidase Inhibition

Exploring architectures displaying multimeric presentations of a trihydroxypiperidine iminosugar.

scientific article published on 16 December 2015

Exploring substituent diversity on pyrrolidine-aryltriazole iminosugars: Structural basis of β-glucocerebrosidase inhibition

scientific article published on 12 February 2019

Glucosylenamines as glycosyl acceptors: synthesis of gentiobiosylenamines.

scientific article

Glycosidase inhibitors as potential HIV entry inhibitors?

scientific article published in August 2004

Harnessing pyrrolidine iminosugars into dimeric structures for the rapid discovery of divalent glycosidase inhibitors

scientific article published on 05 April 2018

Induction of cell killing and autophagy by amphiphilic pyrrolidine derivatives on human pancreatic cancer cells.

scientific article published on 2 March 2018

Mechanistic Insight into the Binding of Multivalent Pyrrolidines to α-Mannosidases

scientific article published on 7 August 2017

New leads for selective inhibitors of alpha-L-fucosidases. Synthesis and glycosidase inhibitory activities of [(2R,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]furan derivatives.

scientific article

Physicochemical characterization of bromide mono- and dimeric surfactants with phenyl and cyclohexyl rings in the head group.

scientific article

Polyhydroxyamino-Piperidine-Type Iminosugars and Pipecolic Acid Analogues from aD-Mannose-Derived Aldehyde

Rapid discovery of potent α-fucosidase inhibitors by in situ screening of a library of (pyrrolidin-2-yl)triazoles

scientific article

Reversibility of the interactions between a novel surfactant derived from lysine and biomolecules.

scientific article published on 31 July 2015

Stable Pyrrole-Linked Bioconjugates through Tetrazine-Triggered Azanorbornadiene Fragmentation

scientific article published on 18 February 2020

Stereoselective Syntheses of 1,4-Dideoxy-1,4-imino-octitols and Novel Tetrahydroxyindolizidines ⬇️

scientific article published on May 16, 2003

Strain-promoted retro-Dieckmann-type condensation on [2.2.2]- and [2.2.1]bicyclic systems: a fragmentation reaction for the preparation of functionalized heterocycles and carbocycles

scientific article

Structural basis of the inhibition of GH1 β-glucosidases by multivalent pyrrolidine iminosugars

scientific article published on 04 June 2019

Study of the Micellization and Micellar Growth in Pure Alkanediyl-α-ω-Bis(dodecyldimethylammonium) Bromide and MEGA10 Surfactant Solutions and Their Mixtures. Influence of the Spacer on the Enthalpy Change Accompanying Sphere-to-Rod Transitions

scientific article published on 01 June 2010

Synthesis and anti-HIV activity of trivalent CD4-mimetic miniproteins.

scientific article published on 24 March 2007

Synthesis and conformational analysis of novel trimeric maleimide cross-linking reagents.

scientific article

Synthesis and glycosidase inhibitory activities of 2-(aminoalkyl)pyrrolidine-3,4-diol derivatives.

scientific article published in November 2003

Synthesis and inhibitory activities of novel C-3 substituted azafagomines: a new type of selective inhibitors of α-L-fucosidases.

scientific article

Synthesis and physicochemical characterization of alkanedyil-α-ω-bis(dimethyldodecylammonium) bromide, 12-s-12,2Br−, surfactants with s=7, 9, 11 in aqueous medium

scientific article published on 02 August 2012

Synthesis of Pyrrolidine 3,4-Diol Derivatives with Anticancer Activity on Pancreatic Tumor Cells

Synthesis, biological evaluation, WAC and NMR studies of S-galactosides and non-carbohydrate ligands of cholera toxin based on polyhydroxyalkylfuroate moieties.

scientific article published on 21 November 2013

Three dimensional structure of a bacterial α-l-fucosidase with a 5-membered iminocyclitol inhibitor

scientific article

Tuning of β-glucosidase and α-galactosidase inhibition by generation and in situ screening of a library of pyrrolidine-triazole hybrid molecules

scientific article published on 27 June 2017

List of works by Inmaculada Robina

6-Azido hyacinthacine A2 gives a straightforward access to the first multivalent pyrrolizidine architectures

A D-ribofuranosylamine as glycosyl acceptor

Allenyl sulfones and allenyl sulfides in the synthesis of 3-pyrrolines. A novel nucleophilic [3 + 2] cycloaddition on allenyl sulfones giving rearranged cycloadducts

An efficient combinatorial method for the discovery of glycosidase inhibitors

Azabicyclic vinyl sulfones for residue-specific dual protein labelling

Derivatives of (2R,3R,4S)-2-aminomethylpyrrolidine-3,4-diol are selective alpha-mannosidase inhibitors.

Differential modulation of SIRT6 deacetylase and deacylase activities by lysine-based small molecules

Discovery of a Potent α-Galactosidase Inhibitor by in Situ Analysis of a Library of Pyrrolizidine-(Thio)urea Hybrid Molecules Generated via Click Chemistry

Effects of Ethylene Glycol Addition on the Aggregation and Micellar Growth of Gemini Surfactants

Epididymal α-l-fucosidase and its possible role in remodelling the surface of bull spermatozoa

Expanding the library of divalent fucosidase inhibitors with polyamino and triazole-benzyl bridged bispyrrolidines

Exploiting the ring strain in bicyclo[2.2.1]heptane systems for the stereoselective preparation of highly functionalized cyclopentene, dihydrofuran, pyrroline, and pyrrolidine scaffolds

Exploring a Multivalent Approach to α-L-Fucosidase Inhibition

Exploring architectures displaying multimeric presentations of a trihydroxypiperidine iminosugar.

Exploring substituent diversity on pyrrolidine-aryltriazole iminosugars: Structural basis of β-glucocerebrosidase inhibition

Glucosylenamines as glycosyl acceptors: synthesis of gentiobiosylenamines.

Glycosidase inhibitors as potential HIV entry inhibitors?

Harnessing pyrrolidine iminosugars into dimeric structures for the rapid discovery of divalent glycosidase inhibitors

Induction of cell killing and autophagy by amphiphilic pyrrolidine derivatives on human pancreatic cancer cells.

Mechanistic Insight into the Binding of Multivalent Pyrrolidines to α-Mannosidases

New leads for selective inhibitors of alpha-L-fucosidases. Synthesis and glycosidase inhibitory activities of [(2R,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]furan derivatives.

Physicochemical characterization of bromide mono- and dimeric surfactants with phenyl and cyclohexyl rings in the head group.

Polyhydroxyamino-Piperidine-Type Iminosugars and Pipecolic Acid Analogues from aD-Mannose-Derived Aldehyde

Rapid discovery of potent α-fucosidase inhibitors by in situ screening of a library of (pyrrolidin-2-yl)triazoles

Reversibility of the interactions between a novel surfactant derived from lysine and biomolecules.

Stable Pyrrole-Linked Bioconjugates through Tetrazine-Triggered Azanorbornadiene Fragmentation

Stereoselective Syntheses of 1,4-Dideoxy-1,4-imino-octitols and Novel Tetrahydroxyindolizidines ⬇️

Strain-promoted retro-Dieckmann-type condensation on [2.2.2]- and [2.2.1]bicyclic systems: a fragmentation reaction for the preparation of functionalized heterocycles and carbocycles

Structural basis of the inhibition of GH1 β-glucosidases by multivalent pyrrolidine iminosugars

Study of the Micellization and Micellar Growth in Pure Alkanediyl-α-ω-Bis(dodecyldimethylammonium) Bromide and MEGA10 Surfactant Solutions and Their Mixtures. Influence of the Spacer on the Enthalpy Change Accompanying Sphere-to-Rod Transitions

Synthesis and anti-HIV activity of trivalent CD4-mimetic miniproteins.

Synthesis and conformational analysis of novel trimeric maleimide cross-linking reagents.

Synthesis and glycosidase inhibitory activities of 2-(aminoalkyl)pyrrolidine-3,4-diol derivatives.

Synthesis and inhibitory activities of novel C-3 substituted azafagomines: a new type of selective inhibitors of α-L-fucosidases.

Synthesis and physicochemical characterization of alkanedyil-α-ω-bis(dimethyldodecylammonium) bromide, 12-s-12,2Br−, surfactants with s=7, 9, 11 in aqueous medium

Synthesis of Pyrrolidine 3,4-Diol Derivatives with Anticancer Activity on Pancreatic Tumor Cells

Synthesis, biological evaluation, WAC and NMR studies of S-galactosides and non-carbohydrate ligands of cholera toxin based on polyhydroxyalkylfuroate moieties.

Three dimensional structure of a bacterial α-l-fucosidase with a 5-membered iminocyclitol inhibitor

Tuning of β-glucosidase and α-galactosidase inhibition by generation and in situ screening of a library of pyrrolidine-triazole hybrid molecules