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List of works by Keyvan Karkouti

A cluster-randomized controlled trial of a blood conservation algorithm in patients undergoing total hip joint arthroplasty

scientific article published in May 2007

A hemorrhage of off-label use

scientific article published on 01 September 2011

A multivariable model for predicting the need for blood transfusion in patients undergoing first-time elective coronary bypass graft surgery

scientific article published in October 2001

A propensity score case-control comparison of aprotinin and tranexamic acid in high-transfusion-risk cardiac surgery.

scientific article published in March 2006

Acute kidney injury after cardiac surgery: focus on modifiable risk factors

scientific article published on 19 January 2009

Acute surgical anemia influences the cardioprotective effects of beta-blockade: a single-center, propensity-matched cohort study

scientific article published in January 2010

Antithrombotic therapy management of adult and pediatric cardiac surgery patients

scientific article published on 30 September 2018

Aprotinin is useful as a hemostatic agent in cardiopulmonary surgery: no.

scientific article published on 27 June 2006

Association of echocardiography before major elective non-cardiac surgery with postoperative survival and length of hospital stay: population based cohort study

scientific article

Blood transfusions and mortality among critically ill patients

scientific article published in March 2003

Calcium antagonists are associated with reduced mortality after cardiac surgery: a propensity analysis

scientific article published in March 2004

Can predicting transfusion in cardiac surgery help patients?

scientific article

Case 6--2007: massive intraoperative thrombosis and death after recombinant activated factor VII administration

scientific article published on 01 December 2007

Case report: management of life-threatening oropharyngeal bleeding with recombinant factor VIIa.

scientific article published in September 2006

Case report: transfusion-related acute lung injury (TRALI) - a clear and present danger.

scientific article published on December 2007

Commentary: recombinant activated factor VII: the controversial conundrum regarding its off-label use

scientific article published on 25 July 2011

Comparison of Two Major Perioperative Bleeding Scores for Cardiac Surgery Trials: Universal Definition of Perioperative Bleeding in Cardiac Surgery and European Coronary Artery Bypass Grafting Bleeding Severity Grade.

scientific article published on 15 March 2018

Comprehensive Canadian review of the off-label use of recombinant activated factor VII in cardiac surgery.

scientific article published on 07 July 2008

Con: Aprotinin has a good efficacy and safety profile relative to other alternatives for prevention of bleeding in cardiac surgery

scientific article published on 01 December 2006

Cryoprecipitate: the current state of knowledge.

scientific article published on July 2009

Defining clinically important perioperative blood loss and transfusion for the Standardised Endpoints for Perioperative Medicine (StEP) collaborative: a protocol for a scoping review

scientific article

Derivation and validation of a simplified predictive index for renal replacement therapy after cardiac surgery

scientific article published in April 2007

Derivation of a risk index for the prediction of massive blood transfusion in liver transplantation

scientific article published in November 2006

Determinants of complications with recombinant factor VIIa for refractory blood loss in cardiac surgery

scientific article published in August 2006

Does tight heart rate control improve beta-blocker efficacy? An updated analysis of the noncardiac surgical randomized trials.

scientific article published in April 2008

Dual antiplatelet therapy in patients requiring urgent coronary artery bypass grafting surgery: a position statement of the Canadian Cardiovascular Society

scientific article published on December 2009

Early rise in postoperative creatinine for identification of acute kidney injury after cardiac surgery.

scientific article published on 19 May 2017

Effectiveness of platelet inhibition on major adverse cardiac events in non-cardiac surgery after percutaneous coronary intervention: a prospective cohort study.

scientific article

Erythropoietin is an effective clinical modality for reducing RBC transfusion in joint surgery

scientific article published in April 2005

Evaluating surrogate measures of renal dysfunction after cardiac surgery

scientific article published on May 2003

Evaluation of a novel transfusion algorithm employing point-of-care coagulation assays in cardiac surgery: a retrospective cohort study with interrupted time-series analysis.

scientific article published in March 2015

From the Journal archives: The red blood cell storage lesion: past, present, and future.

scientific article published on 09 January 2014

Hemodilution during cardiopulmonary bypass is an independent risk factor for acute renal failure in adult cardiac surgery.

scientific article published in February 2005

Hyperglycemia during cardiopulmonary bypass is an independent risk factor for mortality in patients undergoing cardiac surgery

scientific article

Improving the identification of patients at risk of postoperative renal failure after cardiac surgery.

scientific article published in January 2006

In Reply

In reply: Use of early postoperative serum creatinine elevation to identify acute kidney injury after cardiac surgery.

scientific article

Influence of erythrocyte transfusion on the risk of acute kidney injury after cardiac surgery differs in anemic and nonanemic patients

scientific article published in September 2011

Interrelationship of preoperative anemia, intraoperative anemia, and red blood cell transfusion as potentially modifiable risk factors for acute kidney injury in cardiac surgery: a historical multicentre cohort study

scientific article published on 24 December 2014

Intraoperative variables and morbidity and mortality after coronary artery bypass surgery

scientific article published on 01 May 2000

Intravenous iron and recombinant erythropoietin for the treatment of postoperative anemia

scientific article

Is tranexamic acid indicated for total knee replacement surgery?

scientific article published on 01 July 2000

Learning fiberoptic intubation on a simple model transfers to the O.R.

scientific article published in June 2001

Letter by Karkouti and Beattie regarding article "Aprotinin does not increase the risk of renal failure in cardiac surgery patients"

scientific article published on 01 June 2008

Losing sight of the precautionary principle.

scientific article published in August 2017

Low hematocrit during cardiopulmonary bypass is associated with increased risk of perioperative stroke in cardiac surgery.

scientific article published in October 2005

Mild to Moderate Atheromatous Disease of the Thoracic Aorta and New Ischemic Brain Lesions After Conventional Coronary Artery Bypass Graft Surgery

scientific article published on 29 July 2004

Models for difficult laryngoscopy

scientific article published on 01 January 2000

N-acetylcysteine is associated with increased blood loss and blood product utilization during cardiac surgery.

scientific article published in June 2009

Off-label use of recombinant activated factor VII in surgical and non-surgical patients at 16 Canadian hospitals from 2007 to 2010 (Canadian Registry Report).

scientific article published on 3 June 2014

Off-pump coronary artery surgery for reducing mortality and morbidity: meta-analysis of randomized and observational studies

scientific article

Patient blood management during cardiac surgery: do we have enough evidence for clinical practice?

scientific article

Perioperative blood conservation--the experts, the elephants, the clinicians, and the gauntlet

scientific article published on 01 November 2007

Perioperative hemostasis and thrombosis

scientific article published in December 2006

Platelet dysfunction as measured by a point-of-care monitor is an independent predictor of high blood loss in cardiac surgery

scientific article published in February 2014

Platelet transfusions are not associated with increased morbidity or mortality in cardiac surgery

scientific article published in March 2006

Platelet transfusions as a risk factor in cardiac surgery

scientific article published on 01 September 2007

Point-of-Care Hemostatic Testing in Cardiac Surgery: A Stepped-Wedge Clustered Randomized Controlled Trial.

scientific article published on 21 September 2016

Point-of-care viscoelastic hemostatic testing in cardiac surgery patients: a systematic review and meta-analysis

scientific article published on 07 September 2018

Pre-operative anaemia, intra-operative hepcidin concentration and acute kidney injury after cardiac surgery: a retrospective observational study.

scientific article published on 12 March 2018

Predicting difficult intubation: a multivariable analysis

scientific article published in August 2000

Preventing and managing catastrophic bleeding during extracorporeal circulation

scientific article published on 01 November 2018

Pro: Preoperative autologous blood donation has a role in cardiac surgery

scientific article published in February 2003

Pro: The role of recombinant factor VIIa in cardiac surgery

scientific article published on 22 August 2008

Prognostic value of postoperative proteinuria in cardiac surgery: a pilot study

scientific article published in May 2006

Pulmonary-artery catheters in high-risk surgical patients

Recombinant factor VIIa for intractable blood loss after cardiac surgery: a propensity score-matched case-control analysis

scientific article published in January 2005

Red Cell Transfusion-Associated Hemolysis in Cardiac Surgery: An Observational Cohort Study.

scientific article published on 17 February 2017

Reliability of a point-of-care device for international normalized ratio testing during the three surgical phases of orthotopic liver transplantation: a retrospective observational study.

scientific article published on 10 February 2015

Risk associated with preoperative anemia in cardiac surgery: a multicenter cohort study

scientific article published on 2 January 2008

Risk associated with preoperative anemia in noncardiac surgery: a single-center cohort study

scientific article published in March 2009

Risk factors for major complications after extrapleural pneumonectomy for malignant pleural mesothelioma

scientific article published in April 2008

Seek and you shall find--but then what do you do? Cold agglutinins in cardiopulmonary bypass and a single-center experience with cold agglutinin screening before cardiac surgery.

scientific article published on February 2013

Starches for fluid therapy: Is it time for a re-appraisal, or has the horse left the barn? ⬇️

scientific article published on April 30, 2013

Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine (StEP) initiative: renal endpoints

scientific article published on 21 September 2018

Technical report: analysis of citrated blood with thromboelastography: comparison with fresh blood samples.

scientific article published in May 2008

The case for routine screening for SARS-CoV-2 before surgery

scientific article published on 03 June 2020

The clinical dilemma of managing patients who are on dual antiplatelet therapy and require major non-cardiac surgery

scientific article published on 05 November 2018

The effects of a treatment protocol for cardiac surgical patients with excessive blood loss on clinical outcomes.

scientific article published in August 2006

The incremental value of thrombelastography for prediction of excessive blood loss after cardiac surgery: an observational study

scientific article published on 7 July 2010

The independent association of massive blood loss with mortality in cardiac surgery

scientific article published in October 2004

The influence of baseline hemoglobin concentration on tolerance of anemia in cardiac surgery

scientific article published on 10 January 2008

The influence of perioperative coagulation status on postoperative blood loss in complex cardiac surgery: a prospective observational study.

scientific article published on 30 April 2010

The pathophysiology and consequences of red blood cell storage.

scientific article

The pharmacokinetic profile of recombinant human erythropoietin is unchanged in patients undergoing cardiac surgery.

scientific article published on 30 October 2008

The post-BART anti-fibrinolytic dilemma?

scientific article published in February 2011

The rationale for platelet transfusion during cardiopulmonary bypass: an observational study

scientific article

The relationship between fibrinogen levels after cardiopulmonary bypass and large volume red cell transfusion in cardiac surgery: an observational study.

scientific article published on 17 May 2013

The risk-benefit profile of aprotinin versus tranexamic acid in cardiac surgery

scientific article published on 12 November 2009

The role of point-of-care platelet function testing in predicting postoperative bleeding following cardiac surgery: a systematic review and meta-analysis

scientific article published on 27 April 2015

The safety of perioperative esmolol: a systematic review and meta-analysis of randomized controlled trials

scientific article published on 02 December 2010

The utility of thromboelastography for guiding recombinant activated factor VII therapy for refractory hemorrhage after cardiac surgery.

scientific article published on 20 May 2009

Transfusion and risk of acute kidney injury in cardiac surgery ⬇️

scientific article published on December 1, 2012

Universal definition of perioperative bleeding in adult cardiac surgery

scientific article published on 09 December 2013

Use of clinically based troponin underestimates the cardiac injury in non-cardiac surgery: a single-centre cohort study in 51,701 consecutive patients.

scientific article published on 8 September 2012

Use of prothrombin complex concentrate for management of coagulopathy after cardiac surgery: a propensity score matched comparison to plasma.

scientific article published on 24 March 2018

Utilization and Effectiveness of Desmopressin Acetate After Cardiac Surgery Supplemented With Point-of-Care Hemostatic Testing: A Propensity-Score-Matched Analysis.

scientific article

Validity of Thromboelastometry for Rapid Assessment of Fibrinogen Levels in Heparinized Samples During Cardiac Surgery: A Retrospective, Single-center, Observational Study.

scientific article published on 05 May 2015

Variability and predictability of large-volume red blood cell transfusion in cardiac surgery: a multicenter study

scientific article published in November 2007

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