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List of works by Sally A. Cowley

A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response

scientific article

A Simplified Method for Generating Purkinje Cells from Human-Induced Pluripotent Stem Cells.

scientific article

A novel real time imaging platform to quantify macrophage phagocytosis

scientific article published on 27 July 2016

ADAM17-triggered TNF signalling protects the ageing Drosophila retina from lipid droplet-mediated degeneration

scientific article published on 26 July 2020

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

scientific article (publication date: 17 June 1994)

Alpha-synuclein induces the unfolded protein response in Parkinson's disease SNCA triplication iPSC-derived neurons

scientific article

Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics.

scientific article published on 5 January 2016

C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal

scientific article published on 20 April 2016

CRISPR-mediated genotypic and phenotypic correction of a chronic granulomatous disease mutation in human iPS cells.

scientific article

Cellular reprogramming: a new approach to modelling Parkinson's disease.

scientific article published on October 2012

Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson's iPSC-derived dopamine neurons.

scientific article published in June 2019

Derivation and functional analysis of patient-specific induced pluripotent stem cells as an in vitro model of chronic granulomatous disease

scientific article published on April 2012

Differentially expressed, variant U1 snRNAs regulate gene expression in human cells

scientific article published on 15 October 2012

ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons.

scientific article published on 17 February 2016

Efficient, long term production of monocyte-derived macrophages from human pluripotent stem cells under partly-defined and fully-defined conditions

scientific article

Enhancement of cell recovery for dissociated human embryonic stem cells after cryopreservation.

scientific article

Episomal transgene expression in pluripotent stem cells.

scientific article

Excess α-synuclein compromises phagocytosis in iPSC-derived macrophages

scientific article published on 21 August 2017

FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex

scientific article published on 13 June 2018

Functional human artificial chromosomes are generated and stably maintained in human embryonic stem cells

scientific article published on 18 May 2011

Genome editing in induced pluripotent stem cells rescues TAF1 levels in X-linked dystonia-parkinsonism

scientific article published on 01 July 2018

Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27.

scientific article

LRRK2 in peripheral and central nervous system innate immunity: its link to Parkinson's disease.

scientific article published on February 2017

LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages.

scientific article

MAPT Genetic Variation and Neuronal Maturity Alter Isoform Expression Affecting Axonal Transport in iPSC-Derived Dopamine Neurons.

scientific article published on 3 July 2017

Microglial inflammation and phagocytosis in Alzheimer's disease: Potential therapeutic targets

scientific article published on 11 May 2019

Multiplex High-Throughput Targeted Proteomic Assay To Identify Induced Pluripotent Stem Cells

scientific article published on 6 February 2017

Neurodegeneration in SCA14 is associated with increased PKCγ kinase activity, mislocalization and aggregation

scientific article published on 24 September 2018

Physiological characterisation of human iPS-derived dopaminergic neurons

scientific article

Profiling of naïve and primed human pluripotent stem cells reveals state-associated miRNAs

scientific article published on 29 June 2020

Protein kinase C and NF-κB-dependent CD4 downregulation in macrophages induced by T cell-derived soluble factors: consequences for HIV-1 infection

scientific article published on 10 June 2011

RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation

scientific article published on 24 September 2018

Regulation of GATA-2 phosphorylation by mitogen-activated protein kinase and interleukin-3.

scientific article

Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes

scientific article published on 29 November 2018

Stem Cell modeling of Mitochondrial Parkinsonism reveals key functions of OPA1.

scientific article published on 31 March 2018

The Current State of Naïve Human Pluripotency

scientific article published on 29 June 2015

The Mitogen-activated Protein Kinase Kinase MEK1 Stimulates a Pattern of Gene Expression Typical of the Hypertrophic Phenotype in Rat Ventricular Cardiomyocytes

article

The productive entry pathway of HIV-1 in macrophages is dependent on endocytosis through lipid rafts containing CD4.

scientific article published on 22 January 2014

Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson's disease

scientific article

Transportin 3 promotes a nuclear maturation step required for efficient HIV-1 integration.

scientific article

Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease.

scientific article published on 17 August 2016

[29] Assay and expression of mitogen-activated protein kinase, MAP kinase kinase, and Raf

scientific article published on 01 January 1995

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