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List of works by Chris Charles

(Pro)renin Receptor Blockade Ameliorates Cardiac Injury and Remodeling and Improves Function After Myocardial Infarction

scientific article

A neural mechanism for sudden death after myocardial infarction

scientific article published on 1 October 2003

Acute hemodynamic, hormonal, and renal effects of neutral endopeptidase inhibition in ovine heart failure

scientific article published on 01 April 1992

Adrenomedullin 2 attenuates the pressor but not adrenal responses to angiotensin II in conscious sheep

scientific article published on 19 February 2010

Adrenomedullin 2 increases cardiac sympathetic nerve activity in parallel to heart rate in normal conscious sheep

scientific article published on 01 May 2019

Adrenomedullin Attenuates Pressor Response to Angiotensin II in Conscious Sheep

scientific article published in October 2000

Adrenomedullin and heart failure

scientific article

Adrenomedullin and the renin-angiotensin-aldosterone system

scientific article

Adrenomedullin augments the neurohumoral response to haemorrhage in non-pregnant but not in pregnant sheep

scientific article published in November 2001

Adrenomedullin in heart failure

scientific article

Adrenomedullin in heart failure: potential therapeutic implications

scientific article

Adrenomedullin increases cardiac sympathetic nerve activity in normal conscious sheep

scientific article published on 1 November 2005

Adrenomedullin modulates the neurohumoral response to acute volume loading in normal conscious sheep

scientific article

Amino-terminal proBNP in ovine plasma: evidence for enhanced secretion in response to cardiac overload

scientific article published in October 1998

An Ovine Model of Acute Myocardial Infarction and Chronic Left Ventricular Dysfunction ⬇️

scientific article published on August 1, 1997

Angiotensin II receptor antagonism in ovine heart failure: acute hemodynamic, hormonal, and renal effects ⬇️

scientific article published on July 1, 1992

Apelin-13 induces a biphasic haemodynamic response and hormonal activation in normal conscious sheep

scientific article

Arginine vasopressin V1-receptor antagonism in an ovine model of acute myocardial infarction

scientific article published in November 1998

Assay of endopeptidase-24.11 activity in plasma applied to in vivo studies of endopeptidase inhibitors

scientific article published on 1 September 1992

Beneficial hemodynamic and renal effects of adrenomedullin in an ovine model of heart failure

scientific article published in September 1997

Beneficial hemodynamic, endocrine, and renal effects of urocortin in experimental heart failure: comparison with normal sheep

scientific article published in October 2002

Bioactivity of natriuretic peptide coinfusions; no evidence for unique effects of BNP in conscious sheep

scientific article published in February 1999

Biological actions and pharmacokinetics of C-type natriuretic peptide in conscious sheep

scientific article published on 1 January 1995

Biological actions of cleaved atrial natriuretic factor (ANF101-105/106-126) in conscious sheep

scientific article published on 1 March 1991

Bivariate assay for cleaved atrial natriuretic factor (ANF(101-105/106-126)) in sheep plasma

scientific article published on August 13, 1992

Blockade of the renin-angiotensin system

scientific article published on 1 December 1994

Cardiac sympathetic nerve activity and ventricular fibrillation during acute myocardial infarction in a conscious sheep model

scientific article published on 16 March 2007

Cardiovascular actions of ANF: contributions of renal, neurohumoral, and hemodynamic factors in sheep

scientific article published on 01 March 1993

Cardiovascular effects of DWORF (dwarf open reading frame) peptide in normal and ischaemia/reperfused isolated rat hearts

scientific article published on 8 November 2019

Central C-type natriuretic peptide augments the hormone response to hemorrhage in conscious sheep

scientific article published on 01 January 1995

Central C-type natriuretic peptide but not atrial natriuretic factor lowers blood pressure and adrenocortical secretion in normal conscious sheep

scientific article published in October 1992

Central angiotensin II AT1-receptor antagonism in normal and heart-failed sheep ⬇️

scientific article published on August 1, 1995

Chronic infusions of brain natriuretic peptide in conscious sheep: bioactivity at low physiological levels

scientific article published in December 1998

Chronic ouabain infusion does not cause hypertension in sheep

scientific article published on 1 March 1996

Clearance receptors and endopeptidase 24.11: equal role in natriuretic peptide metabolism in conscious sheep

scientific article published in August 1996

Clearance receptors and endopeptidase: equal role in natriuretic peptide metabolism in heart failure ⬇️

scientific article published on November 1, 1997

Combined angiotensin-converting enzyme inhibition and adrenomedullin in an ovine model of heart failure

scientific article published in June 2002

Combined endopeptidase inhibition and adrenomedullin in sheep with experimental heart failure

scientific article published in January 2002

Combined inhibition of angiotensin II and endothelin suppresses the brain natriuretic peptide response to developing heart failure

scientific article

Combined neutral endopeptidase and angiotensin-converting enzyme inhibition in heart failure: role of natriuretic peptides and angiotensin II

scientific article

Comparative actions of adrenomedullin and nitroprusside: interactions with ANG II and norepinephrine ⬇️

scientific article published on December 1, 2001

Comparative bioactivity of atrial and brain natriuretic peptides in an ovine model of heart failure

scientific article published on 1 February 1997

Comparative bioactivity of atrial, brain, and C-type natriuretic peptides in conscious sheep

scientific article published on 1 June 1996

Comparative pathology of an implantable left atrial pressure sensor

scientific article published on 01 September 2013

Comparative pharmacokinetics and pharmacodynamics of urocortins 1, 2 and 3 in healthy sheep

scientific article

Comparison of chronic neutral endopeptidase inhibition and furosemide in an ovine model of heart failure

scientific article published on 1 March 1996

Comparison of the effect of renin inhibition and angiotensin-converting enzyme inhibition in ovine heart failure

scientific article published in February 1992

Comparison of the effects of ouabain and brain natriuretic peptide in saline-loaded sheep ⬇️

scientific article published on November 1, 1997

Continual recordings of cardiac sympathetic nerve activity in conscious sheep ⬇️

scientific article published on January 1, 2002

Delayed metabolism of human brain natriuretic peptide reflects resistance to neutral endopeptidase.

scientific article published on November 2000

Endogenous urocortins reduce vascular tone and renin-aldosterone/endothelin activity in experimental heart failure

scientific article published on 8 April 2005

Endopeptidase inhibition in angiotensin-induced hypertension. Effect of SCH 39370 in sheep

scientific article published on 01 July 1995

Extracellular Vesicles in Cardiovascular Diseases: Alternative Biomarker Sources, Therapeutic Agents, and Drug Delivery Carriers

scientific article published on 3 July 2019

Four-day urocortin-I administration has sustained beneficial haemodynamic, hormonal, and renal effects in experimental heart failure

scientific article published on 16 June 2005

Haemodynamic, endocrine and renal actions of adrenomedullin 5 in an ovine model of heart failure

scientific article published in May 2012

Hemodynamic and hormonal effects of neutral endopeptidase inhibitor SCH 39370 in sheep.

scientific article published on May 1991

Hemodynamic and hormonal effects of renin inhibition in ovine heart failure

scientific article published on 1 June 1990

Hemodynamic, Hormonal, and Renal Actions of Phosphodiesterase-9 Inhibition in Experimental Heart Failure

scientific article published on 1 August 2019

Hemodynamic, Hormonal, and Renal Effects of Intracerebroventricular Adrenomedullin in Conscious Sheep1

scientific article published in April 1998

Hemodynamic, hormonal, and renal actions of adrenomedullin 2 in experimental heart failure

scientific article published on 28 May 2008

Hemodynamic, hormonal, and renal actions of adrenomedullin-2 in normal conscious sheep

scientific article published on 12 January 2006

Hemodynamic, hormonal, and renal actions of adrenomedullin-5 in normal conscious sheep

scientific article published on 01 July 2011

Hemodynamic, hormonal, and renal effects of (pro)renin receptor blockade in experimental heart failure

scientific article published on 12 July 2012

Hemodynamic, hormonal, and renal effects of adrenomedullin in conscious sheep ⬇️

scientific article published on June 1, 1997

Hemodynamic, renal, and endocrine actions of ANF in sheep: effect of 24-h, low-dose infusions

scientific article published on 1 May 1990

Human muscle sympathetic nerve responses to urocortin-2 in health and stable heart failure

scientific article published on 1 September 2015

Hypothalamo-pituitary-adrenal axis response to coronary artery embolization: an ovine model of acute myocardial infarction

scientific article

Identification and biological activity of ovine and caprine calcitonin receptor-stimulating peptides 1 and 2.

scientific article published on 15 May 2008

Identification of novel microRNAs in the sheep heart and their regulation in heart failure

scientific article published on 15 August 2017

Increased cardiac sympathetic nerve activity following acute myocardial infarction in a sheep model

scientific article

Integrated hemodynamic, hormonal, and renal actions of urocortin 2 in normal and paced sheep: beneficial effects in heart failure

scientific article

Integrated microscopy techniques for comprehensive pathology evaluation of an implantable left atrial pressure sensor

scientific article published on March 2013

Interactions of enhanced urocortin 2 and mineralocorticoid receptor antagonism in experimental heart failure

scientific article published on 10 June 2013

Intracerebroventricular atrial natriuretic factor (ANF) antiserum inhibits volume-induced ANF in sheep: evidence for the brain's regulation of ANF secretion

scientific article published in October 1991

Large Animal Models of Heart Failure: Reduced vs. Preserved Ejection Fraction

scientific article published on 18 October 2020

Long-term adrenomedullin administration in experimental heart failure

scientific article published in November 2002

Low-dose B-type natriuretic peptide raises cardiac sympathetic nerve activity in sheep

scientific article published on 7 May 2014

Monitoring of heart failure: comparison of left atrial pressure with intrathoracic impedance and natriuretic peptide measurements in an experimental model of ovine heart failure

scientific article published in March 2011

Myocardial infarction with and without reperfusion in sheep: early cardiac and neurohumoral changes

scientific article

Natriuretic peptide responses to acute and chronic ventricular pacing in sheep

scientific article published in February 1996

Natriuretic peptides in sheep with pressure overload left ventricular hypertrophy

scientific article

Natriuretic peptides maintain sodium homoeostasis during chronic volume loading post-myocardial infarction in sheep

scientific article published in April 2003

Neurohormones in an ovine model of compensated postinfarction left ventricular dysfunction

scientific article published on 1 March 2000

Neutral endopeptidase inhibition: augmented atrial and brain natriuretic peptide, haemodynamic and natriuretic responses in ovine heart failure

scientific article

Nitric oxide inhibition in an ovine model of heart failure

scientific article published on 1 May 1996

Ovine brain natriuretic peptide in cardiac tissues and plasma: effects of cardiac hypertrophy and heart failure on tissue concentration and molecular forms

scientific article published in December 1997

Plasma urocortin 1 in sheep: regional sampling and effects of experimental heart failure

scientific article published on 25 January 2006

Prolonged urocortin 2 administration in experimental heart failure: sustained hemodynamic, endocrine, and renal effects

scientific article published on 2 May 2011

Putative role for apelin in pressure/volume homeostasis and cardiovascular disease.

scientific article published on January 2007

Regional sampling and the effects of experimental heart failure in sheep: differential responses in A, B and C-type natriuretic peptides

scientific article published on 10 August 2005

Skeletal contributions to plasma CNP forms: evidence from regional sampling in growing lambs

scientific article published on 5 August 2009

Systemic angiotensin II does not increase cardiac sympathetic nerve activity in normal conscious sheep

scientific article published on 17 October 2018

The apelin peptides as putative targets in cardiovascular drug discovery and development.

scientific article published on January 2008

The ovine hypothalamus and pituitary have markedly different distribution of C-type natriuretic peptide forms

scientific article

The role of adrenomedullin

scientific article

Thoracic impedance measures tissue characteristics in the vicinity of the electrodes, not intervening lung water: implications for heart failure monitoring

scientific article published on 12 March 2014

Treatment of Staphylococcus epidermidis central vascular catheter infection with 70% ethanol locks: efficacy in a sheep model.

scientific article published on 5 February 2007

Update on apelin peptides as putative targets for cardiovascular drug discovery

scientific article published on 24 March 2011

Urocortin 1 administration from onset of rapid left ventricular pacing represses progression to overt heart failure

scientific article

Urocortin 1 exhibits potent inhibition of cardiac sympathetic nerve activity in conscious sheep

scientific article published on 1 January 2008

Urocortin 1 modulates the neurohumoral response to acute nitroprusside-induced hypotension in sheep

scientific article published in July 2007

Urocortin 2 combined with angiotensin-converting enzyme inhibition in experimental heart failure

scientific article published in May 2008

Urocortin 2 induces potent long-lasting inhibition of cardiac sympathetic drive despite baroreflex activation in conscious sheep

scientific article published on 13 November 2009

Urocortin 2 inhibits furosemide-induced activation of renin and enhances renal function and diuretic responsiveness in experimental heart failure

scientific article published on 22 September 2009

Urocortin 2 protects heart and kidney structure and function in an ovine model of acute decompensated heart failure: Comparison with dobutamine

scientific article

Urocortin 2 sustains haemodynamic and renal function during introduction of beta-blockade in experimental heart failure

scientific article published on 1 September 2011

Urocortin 3 Inhibits Cardiac Sympathetic Nerve Activity in Conscious Sheep ⬇️

scientific article published on 01 October 2011

Urocortin 3: haemodynamic, hormonal, and renal effects in experimental heart failure

scientific article published on 06 July 2006

Urocortins: putative role in cardiovascular disease

scientific article

Urotensin II in the cardiovascular system.

scientific article published in October 2004

Urotensin II: evidence for cardiac, hepatic and renal production

scientific article published on 19 April 2005

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