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List of works by Giuseppe Testa

7q11.23 dosage-dependent dysregulation in human pluripotent stem cells affects transcriptional programs in disease-relevant lineages

scientific article published on 15 December 2014

Activation of neuronal gene expression by the JMJD3 demethylase is required for postnatal and adult brain neurogenesis.

scientific article published on 28 August 2014

Autism spectrum disorder at the crossroad between genes and environment: contributions, convergences, and interactions in ASD developmental pathophysiology

scientific article published on 10 September 2020

BAC engineering for the generation of ES cell-targeting constructs and mouse transgenes

scientific article published in January 2004

Bacterial artificial chromosome transgenesis through pronuclear injection of fertilized mouse oocytes.

scientific article published in January 2008

Breakdown of the potentiality principle and its impact on global stem cell research

scientific article published on 01 August 2007

Brief report: functional MRI of a patient with 7q11.23 duplication syndrome and autism spectrum disorder

scientific article published in October 2014

Cell reprogramming requires silencing of a core subset of polycomb targets

scientific article

Correction: Curation of causal interactions mediated by genes associated with autism accelerates the understanding of gene-phenotype relationships underlying neurodevelopmental disorders

scientific article published in 2024

Curation of causal interactions mediated by genes associated with autism accelerates the understanding of gene-phenotype relationships underlying neurodevelopmental disorders

scientific article published in 2023

DNA cloning by homologous recombination in Escherichia coli

scientific article published on 01 December 2000

DNA damage in mammalian neural stem cells leads to astrocytic differentiation mediated by BMP2 signaling through JAK-STAT

scientific article published on 25 July 2013

Dosage analysis of the 7q11.23 Williams region identifies BAZ1B as a major human gene patterning the modern human face and underlying self-domestication

scientific article published on 04 December 2019

ET recombination: DNA engineering using homologous recombination in E. coli

scientific article published in January 2004

Engineering the mouse genome with bacterial artificial chromosomes to create multipurpose alleles.

scientific article published on 10 March 2003

Epigenomic landscape of human colorectal cancer unveils an aberrant core of pan-cancer enhancers orchestrated by YAP/TAZ

scientific article published on 20 April 2021

Ethical standards for human-to-animal chimera experiments in stem cell research

article

Ethics and synthetic gametes

scientific article published in April 2005

Ethics report on interspecies somatic cell nuclear transfer research

scientific article published on 01 July 2009

Exploiting epigenetic dependencies in ovarian cancer therapy

scientific article published in 2021

Genetics. Ethical aspects of ES cell-derived gametes

scientific article published in September 2004

Genomic, Proteomic and Phenotypic Heterogeneity in HeLa Cells across Laboratories: Implications for Reproducibility of Research Results

Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis.

scientific article published on 8 November 2013

HOXB7 overexpression in lung cancer is a hallmark of acquired stem-like phenotype.

scientific article published on 26 March 2018

High-throughput screening identifies histone deacetylase inhibitors that modulate GTF2I expression in 7q11.23 microduplication autism spectrum disorder patient-derived cortical neurons

scientific article published on 19 November 2020

Imbalanced autophagy causes synaptic deficits in a human model for neurodevelopmental disorders

scientific article published on 21 July 2021

JMJD3 acts in tandem with KLF4 to facilitate reprogramming to pluripotency

scientific article published on 08 October 2020

Jmjd3 contributes to the control of gene expression in LPS-activated macrophages

scientific article published on 24 September 2009

KMT2B and Neuronal Transdifferentiation: Bridging Basic Chromatin Mechanisms to Disease Actionability

scientific article published on 14 June 2020

Mast cell-specific Cre/loxP-mediated recombination in vivo

scientific article

Microinjection of BAC DNA into the pronuclei of fertilized mouse oocytes

scientific article published in January 2004

Multiplex parenting: IVG and the generations to come

scientific article

Pluripotency and differentiation in embryos and stem cells.

scientific article published in January 2008

Polycomb dysregulation in gliomagenesis targets a Zfp423-dependent differentiation network

scientific article published on 29 February 2016

Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication

scientific article published on 14 April 2014

Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine

scientific article published on 17 March 2021

RNAontheBENCH: computational and empirical resources for benchmarking RNAseq quantification and differential expression methods

scientific article

Rapid modification of bacterial artificial chromosomes by ET-recombination.

scientific article published on March 1999

Reconstitution of a functional human thymus by postnatal stromal progenitor cells and natural whole-organ scaffolds

scientific article published on 11 December 2020

Reprogramming potentiality: the co-production of stem cell policy and democracy

scientific article published in January 2013

Scrutinizing the EU General Data Protection Regulation

scientific article

Scrutinizing the epigenetics revolution.

scientific article

Systematic proteome and proteostasis profiling in human Trisomy 21 fibroblast cells.

scientific article published on 31 October 2017

TRIC: an automated alignment strategy for reproducible protein quantification in targeted proteomics

scientific article published on August 2016

The H3K27 demethylase JMJD3 is required for maintenance of the embryonic respiratory neuronal network, neonatal breathing, and survival.

scientific article

The chromatin basis of neurodevelopmental disorders: Rethinking dysfunction along the molecular and temporal axes.

scientific article published on 5 January 2018

The future therapeutic potential of histone demethylases: A critical analysis.

scientific article published on September 2009

The histone H3 lysine 27-specific demethylase Jmjd3 is required for neural commitment

scientific article

The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing

scientific journal article

The histone methyltransferase Wbp7 controls macrophage function through GPI glycolipid anchor synthesis

scientific article published on 5 April 2012

The methyltransferase Set7/9 (Setd7) is dispensable for the p53-mediated DNA damage response in vivo.

scientific article

The sociability spectrum: evidence from reciprocal genetic copy number variations

scientific article published on 16 June 2020

The time of timing: How Polycomb proteins regulate neurogenesis ⬇️

scientific article published on June 1, 2011

Thinking "ethical" when designing an international, cross-disciplinary biomedical research consortium

scientific article published on 07 September 2020

What to do with the Grail now that we have it? iPSCs, potentiality, and public policy

scientific article published in October 2009

YY1 Haploinsufficiency Causes an Intellectual Disability Syndrome Featuring Transcriptional and Chromatin Dysfunction

scientific article published on June 2017

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