Search filters

List of works by Jörg Steinbach

(177)Lu-labelled macrocyclic bisphosphonates for targeting bone metastasis in cancer treatment

scientific article

(18)F-Labeled 1,4-Dioxa-8-azaspiro[4.5]decane Derivative: Synthesis and Biological Evaluation of a σ1 Receptor Radioligand with Low Lipophilicity as Potent Tumor Imaging Agent

scientific article

(99m)Tc-Cyclopentadienyl Tricarbonyl Chelate-Labeled Compounds as Selective Sigma-2 Receptor Ligands for Tumor Imaging.

scientific article published on 7 January 2016

4-[18F]Fluoro-N-methyl-N-(propyl-2-yn-1-yl)benzenesulfonamide ([18F]F-SA): a versatile building block for labeling of peptides, proteins and oligonucleotides with fluorine-18 via Cu(I)-mediated click chemistry

scientific article published on 10 January 2013

A Promising PET Tracer for Imaging of α₇ Nicotinic Acetylcholine Receptors in the Brain: Design, Synthesis, and in Vivo Evaluation of a Dibenzothiophene-Based Radioligand

scientific article published on 9 October 2015

A fluoro versus a nitro derivative-a high-performance liquid chromatography study of two basic analytes with different reversed phases and silica phases as basis for the separation of a positron emission tomography radiotracer.

scientific article published on 27 August 2013

A novel nanobody-based target module for retargeting of T lymphocytes to EGFR-expressing cancer cells via the modular UniCAR platform.

scientific article

An automatic method for accurate volume delineation of heterogeneous tumors in PET.

scientific article published in August 2013

An efficient bioorthogonal strategy using CuAAC click chemistry for radiofluorinations of SNEW peptides and the role of copper depletion.

scientific article published on 4 April 2013

Automation of the radiosynthesis and purification procedures for [18F]Fluspidine preparation, a new radiotracer for clinical investigations in PET imaging of σ(1) receptors in brain

scientific article published on 5 November 2013

Bevacizumab Plus Irinotecan Versus Temozolomide in Newly Diagnosed O6-Methylguanine-DNA Methyltransferase Nonmethylated Glioblastoma: The Randomized GLARIUS Trial

scientific article published on 14 March 2016

Convenient recycling and reuse of bombarded [¹⁸O]H₂O for the production and the application of [¹⁸F]F⁻.

scientific article

Cryogel-supported stem cell factory for customized sustained release of bispecific antibodies for cancer immunotherapy

scientific article published on 16 February 2017

Cyclopeptides containing the DEKS motif as conformationally restricted collagen telopeptide analogues: synthesis and conformational analysis.

scientific article

Cytotoxic properties of radionuclide-conjugated Cetuximab without and in combination with external irradiation in head and neck cancer cells in vitro.

scientific article published on 3 April 2014

Development of (18)F-labeled radiotracers for neuroreceptor imaging with positron emission tomography

scientific article

Development of a Novel Nonpeptidic (18)F-Labeled Radiotracer for in Vivo Imaging of Oxytocin Receptors with Positron Emission Tomography.

scientific article published on 21 January 2016

Development of highly potent phosphodiesterase 10A (PDE10A) inhibitors: Synthesis and in vitro evaluation of 1,8-dipyridinyl- and 1-pyridinyl-substituted imidazo[1,5-a]quinoxalines

scientific article published on 19 October 2015

Development of indazolylpyrimidine derivatives as high-affine EphB4 receptor ligands and potential PET radiotracers

scientific article published on 2 July 2015

Development of novel target modules for retargeting of UniCAR T cells to GD2 positive tumor cells

scientific article published on 18 September 2017

Direct and Auger Electron-Induced, Single- and Double-Strand Breaks on Plasmid DNA Caused by 99mTc-Labeled Pyrene Derivatives and the Effect of Bonding Distance

scientific article

Distinctive in vivo kinetics of the new σ1 receptor ligands (R)-(+)- and (S)-(-)-18F-fluspidine in porcine brain

scientific article published on 28 July 2014

EGF receptor-targeting peptide conjugate incorporating a near-IR fluorescent dye and a novel 1,4,7-triazacyclononane-based (64)Cu(II) chelator assembled via click chemistry.

scientific article

Effect of [(18)F]FMISO stratified dose-escalation on local control in FaDu hSCC in nude mice

scientific article published on 14 March 2014

Engrafting human regulatory T cells with a flexible modular chimeric antigen receptor technology.

scientific article published in March 2018

ErbB2/HER2-Specific NK Cells for Targeted Therapy of Glioblastoma.

scientific article published on 6 December 2015

Evaluation of PET quantification accuracy in vivo. Comparison of measured FDG concentration in the bladder with urine samples.

scientific article published on 20 February 2014

Evaluation of in vivo quantification accuracy of the Ingenuity-TF PET/MR.

scientific article

Evaluation of metabolism, plasma protein binding and other biological parameters after administration of (-)-[(18)F]Flubatine in humans

scientific article published on 29 March 2014

Evaluation of the Enantiomer Specific Biokinetics and Radiation Doses of [(18)F]Fluspidine-A New Tracer in Clinical Translation for Imaging of σ₁ Receptors.

scientific article

From mono- to bivalent: improving theranostic properties of target modules for redirection of UniCAR T cells against EGFR-expressing tumor cells in vitro and in vivo.

scientific article published on 22 May 2018

Gelatin-based Hydrogel Degradation and Tissue Interaction in vivo: Insights from Multimodal Preclinical Imaging in Immunocompetent Nude Mice.

scientific article published on 12 September 2016

Imaging of α7 nicotinic acetylcholine receptors in brain and cerebral vasculature of juvenile pigs with [(18)F]NS14490.

scientific article

Impact of pre- and early per-treatment FDG-PET based dose-escalation on local tumour control in fractionated irradiated FaDu xenograft tumours.

scientific article published on 17 August 2016

In vivo demonstration of an active tumor pretargeting approach with peptide nucleic acid bioconjugates as complementary system.

scientific article published on 17 June 2015

Internal dose assessment of (-)-18F-flubatine, comparing animal model datasets of mice and piglets with first-in-human results

scientific article published on 6 October 2014

Investigation of an 18F-labelled Imidazopyridotriazine for Molecular Imaging of Cyclic Nucleotide Phosphodiesterase 2A

scientific article published on 02 March 2018

LC-MS Supported Studies on the in Vitro Metabolism of both Enantiomers of Flubatine and the in Vivo Metabolism of (+)-[(18)F]Flubatine-A Positron Emission Tomography Radioligand for Imaging α4β2 Nicotinic Acetylcholine Receptors.

scientific article published on 8 September 2016

NDRG1 prognosticates the natural course of disease in WHO grade II glioma

scientific article published on 7 January 2014

New systematically modified vesamicol analogs and their affinity and selectivity for the vesicular acetylcholine transporter - A critical examination of the lead structure

scientific article published on 22 May 2015

Novel (pyrazolyl)benzenesulfonamides with a nitric oxide-releasing moiety as selective cyclooxygenase-2 inhibitors

scientific article published on 29 May 2015

Novel cyclopentadienyl tricarbonyl (99m)tc complexes containing 1-piperonylpiperazine moiety: potential imaging probes for sigma-1 receptors

scientific article

Potential of a Cetuximab-based radioimmunotherapy combined with external irradiation manifests in a 3-D cell assay.

scientific article published on 11 February 2014

Preparation of a novel radiotracer targeting the EphB4 receptor via radiofluorination using spiro azetidinium salts as precursor

scientific article published on 31 May 2017

Radiofluorination and first radiopharmacological characterization of a SWLAY peptide-based ligand targeting EphA2.

scientific article published on 29 September 2014

Radiolabeled anti-EGFR-antibody improves local tumor control after external beam radiotherapy and offers theragnostic potential

scientific article published on 16 January 2014

Radiopharmacological characterization of ⁶⁴Cu-labeled α-MSH analogs for potential use in imaging of malignant melanoma

scientific article published on 07 December 2015

Radiosynthesis and biological evaluation of the new PDE10A radioligand [18 F]AQ28A.

scientific article published on 29 November 2016

Recent progress using the Staudinger ligation for radiolabeling applications.

scientific article published on 11 September 2017

Retargeting of T lymphocytes to PSCA- or PSMA positive prostate cancer cells using the novel modular chimeric antigen receptor platform technology "UniCAR".

scientific article

Retargeting of UniCAR T cells with an in vivo synthesized target module directed against CD19 positive tumor cells

scientific article published on 21 December 2017

Spatial distribution of FMISO in head and neck squamous cell carcinomas during radio-chemotherapy and its correlation to pattern of failure.

scientific article published on 23 September 2015

Synthesis and biodistribution studies of (3)H- and (64)Cu-labeled dendritic polyglycerol and dendritic polyglycerol sulfate

scientific article published on 11 May 2015

Synthesis and biological evaluation of both enantiomers of [(18)F]flubatine, promising radiotracers with fast kinetics for the imaging of α4β2-nicotinic acetylcholine receptors.

scientific article

Synthesis and evaluation of a (18) F-labeled 4-phenylpiperidine-4-carbonitrile radioligand for σ1 receptor imaging

scientific article published on 9 June 2016

Synthesis and evaluation of a 18F-labeled spirocyclic piperidine derivative as promising σ1 receptor imaging agent.

scientific article published on 12 August 2014

Synthesis, 18F-Radiolabelling and Biological Characterization of Novel Fluoroalkylated Triazine Derivatives for in Vivo Imaging of Phosphodiesterase 2A in Brain via Positron Emission Tomography.

scientific article

Synthesis, radiolabelling and initial biological characterisation of 18F-labelled xanthine derivatives for PET imaging of Eph receptors

scientific article published on 07 April 2020

Theranostic mercury: (197(m))Hg with high specific activity for imaging and therapy

scientific article published on 05 January 2015

Tos-Nos-Mos: Synthesis of different aryl sulfonate precursors for the radiosynthesis of the alpha7 nicotinic acetylcholine receptor radioligand [(18)F]NS14490.

scientific article published on 28 April 2016