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List of works by Daniel Gackowski

5-Formylcytosine and 5-hydroxymethyluracil as surrogate markers of TET2 and SF3B1 mutations in myelodysplastic syndrome, respectively

scientific article published on 05 September 2019

8-Oxo-7,8-dihydroguanine and uric acid as efficient predictors of survival in colon cancer patients

scientific article published on 5 August 2013

8-Oxoguanine incision activity is impaired in lung tissues of NSCLC patients with the polymorphism of OGG1 and XRCC1 genes

article

Aberrant repair of etheno-DNA adducts in leukocytes and colon tissue of colon cancer patients

scientific article published on 28 June 2010

Accurate, Direct, and High-Throughput Analyses of a Broad Spectrum of Endogenously Generated DNA Base Modifications with Isotope-Dilution Two-Dimensional Ultraperformance Liquid Chromatography with Tandem Mass Spectrometry: Possible Clinical Implica

scientific article published on 8 December 2016

An IDH-independent mechanism of DNA hypermethylation upon VHL inactivation in cancer

scientific article published on 8 September 2021

An IDH-independent mechanism of DNA hypermethylation upon VHL inactivation in cancer

scientific article published on 10 December 2020

Analysis of 5-Hydroxymethyluracil Levels Using Flow Cytometry

scientific article published on 01 January 2021

Are 8-oxoguanine (8-oxoGua) and 5-hydroxymethyluracil (5-hmUra) oxidatively damaged DNA bases or transcription (epigenetic) marks?

scientific article

Cellular level of 8-oxo-2'-deoxyguanosine in DNA does not correlate with urinary excretion of the modified base/nucleoside.

scientific article published in January 2003

Characteristic profiles of DNA epigenetic modifications in colon cancer and its predisposing conditions-benign adenomas and inflammatory bowel disease.

scientific article

Comparison of oxidative stress/DNA damage in semen and blood of fertile and infertile men

scientific article

Comparison of the Absolute Level of Epigenetic Marks 5-Methylcytosine, 5-Hydroxymethylcytosine, and 5-Hydroxymethyluracil Between Human Leukocytes and Sperm1

scientific article published on 24 July 2014

Context dependent effects of ascorbic acid treatment in TET2 mutant myeloid neoplasia

scientific article published on 07 September 2020

Contribution of hMTH1 to the maintenance of 8-oxoguanine levels in lung DNA of non-small-cell lung cancer patients

scientific article published in March 2005

Correction: Profiles of a broad spectrum of epigenetic DNA modifications in normal and malignant human cell lines: Proliferation rate is not the major factor responsible for the 5-hydroxymethyl-2'-deoxycytidine level in cultured cancerous cell lines

scientific article

Cu,Zn-superoxide dismutase deficiency in mice leads to organ-specific increase in oxidatively damaged DNA and NF-κB1 protein activity.

scientific article published on 9 November 2010

DNA repair is responsible for the presence of oxidatively damaged DNA lesions in urine

scientific article

Decreased repair activities of 1,N(6)-ethenoadenine and 3,N(4)-ethenocytosine in lung adenocarcinoma patients.

scientific article published in August 2003

Detection and Quantification of RNA Modifications on RNA–DNA Hybrids Using SID-UPLC-MS/MS

scientific article published in 2022

Diagnostic and Prognostic Power of Active DNA Demethylation Pathway Intermediates in Acute Myelogenous Leukemia and Myelodysplastic Syndromes

scientific article published on 4 March 2022

Diet is not responsible for the presence of several oxidatively damaged DNA lesions in mouse urine

scientific article published in November 2004

Does morphology of carotid plaque depend on patient's oxidative stress?

scientific article published on 29 May 2013

Dynamic changes in genomic 5-hydroxymethyluracil and N6-methyladenine levels in the Drosophila melanogaster life cycle and in response to different temperature conditions

scientific article published on 20 October 2022

Dynamics of estrogen-induced oxidative stress.

scientific article published on 15 May 2007

Dynamics of oxidative damage at early stages of estrogen-dependant carcinogenesis.

scientific article published in January 2008

ERCC1-deficient cells and mice are hypersensitive to lipid peroxidation

Effects of basal level of antioxidants on oxidative DNA damage in humans

scientific article

Elevated level of 8-oxo-7,8-dihydro-2'-deoxyguanosine in leukocytes of BRCA1 mutation carriers compared to healthy controls.

scientific article published in November 2009

Endogenous oxidative DNA base modifications analysed with repair enzymes and GC/MS technique

scientific article published on March 2000

Endogenously generated DNA nucleobase modifications source, and significance as possible biomarkers of malignant transformation risk, and role in anticancer therapy

scientific article

Enigmatic 5-hydroxymethyluracil: Oxidatively modified base, epigenetic mark or both?

scientific article published on January 2016

Epigenetic modifications and NF-κB pathway activity in Cu,Zn-SOD-deficient mice

scientific article published on 20 August 2014

Evidence for attenuated cellular 8-oxo-7,8-dihydro-2′-deoxyguanosine removal in cancer patients

scientific article published on 01 April 2006

Global hypomethylation pattern in systemic sclerosis: An application for absolute quantification of epigenetic DNA modification products by 2D-UPLC-MS/MS

scientific article published in June 2022

Helicobacter pylori infection is associated with oxidatively damaged DNA in human leukocytes and decreased level of urinary 8-oxo-7,8-dihydroguanine

scientific article

High concentrations of excised oxidative DNA lesions in human cerebrospinal fluid

scientific article

Higher Leukocyte 8-Oxo-7,8-Dihydro-2'-Deoxyguanosine and Lower Plasma Ascorbate in Aging Humans?

scientific article published on 01 January 2007

Human and methodological sources of variability in the measurement of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine.

scientific article published on 31 January 2013

In vivo evidence of ascorbate involvement in the generation of epigenetic DNA modifications in leukocytes from patients with colorectal carcinoma, benign adenoma and inflammatory bowel disease

scientific article published on 20 July 2018

Interlaboratory comparison of methodologies for the measurement of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine

scientific article

LINE-1 transcription in round spermatids is associated with accretion of 5-carboxylcytosine in their open reading frames

scientific article published on 7 June 2021

Lymphocyte labile iron pool, plasma iron, transferrin saturation and ferritin levels in colon cancer patients

scientific article published on 01 January 2002

Mass Spectrometry-Based Analysis of DNA Modifications: Potential Applications in Basic Research and Clinic

scientific article published on 01 January 2021

Mass spectrometry reveals the presence of specific set of epigenetic DNA modifications in the Norway spruce genome

scientific article published on 17 December 2019

Modulation of TET2 Activity By Ascorbic Acid and Factors Affecting Lysine Acetylation

scientific article published on 29 November 2018

N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells

scientific article published on 16 December 2019

Normalization of metabolic data to total thymine content and its application to determination of 2-hydroxyglutarate

scientific article

Nucleotide excision repair of oxidised genomic DNA is not a source of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine

scientific article

Oxidation Products of 5-Methyl Cytosine are Decreased in Senescent Cells and Tissues of Progeroid Mice.

scientific article published on 3 February 2018

Oxidative DNA damage and antioxidant vitamin level: comparison among lung cancer patients, healthy smokers and nonsmokers

scientific article

Oxidative DNA damage in cancer patients: a cause or a consequence of the disease development?

scientific article published on October 2003

Oxidative DNA damage: assessment of the role in carcinogenesis, atherosclerosis, and acquired immunodeficiency syndrome

scientific article

Oxidative damage to DNA and antioxidant status in aging and age-related diseases.

scientific article published on 9 January 2007

Oxidative stress and 8-oxoguanine repair are enhanced in colon adenoma and carcinoma patients

scientific article published on 9 June 2010

Oxidative stress and oxidative DNA damage is characteristic for mixed Alzheimer disease/vascular dementia

scientific article published on 20 September 2007

Oxidatively damaged DNA/oxidative stress in children with celiac disease

scientific article published on August 2010

Persistent oxidative stress in colorectal carcinoma patients

scientific article

Plasma micronutrients, trace elements, and breast cancer in BRCA1 mutation carriers: an exploratory study

scientific article published on 11 May 2012

Polystyrene nanoparticles: the mechanism of their genotoxicity in human peripheral blood mononuclear cells

scientific article published on 14 September 2022

Preparation of Internal Standards for 2D-UPLC-MS/MS Quantification of Noncanonical DNA Bases

scientific article published on 01 January 2021

Products of oxidative DNA damage and repair as possible biomarkers of susceptibility to lung cancer

scientific article published in August 2003

Profiles of a broad spectrum of epigenetic DNA modifications in normal and malignant human cell lines: Proliferation rate is not the major factor responsible for the 5-hydroxymethyl-2'-deoxycytidine level in cultured cancerous cell lines

scientific article published on 30 November 2017

Quantification of DNA Modifications Using Two-Dimensional Ultraperformance Liquid Chromatography Tandem Mass Spectrometry (2D-UPLC-MS/MS)

scientific article published on 01 January 2021

Selective Estrogen Receptor Modulators' (SERMs) Influence on Expression in Breast Cancer Cell Lines with Distinct Biological Subtypes

scientific article published on 6 August 2024

Selenium supplementation reduced oxidative DNA damage in adnexectomized BRCA1 mutations carriers

scientific article published on 20 October 2009

Severe oxidatively damaged DNA after cisplatin treatment of cancer patients

scientific article published on 01 November 2006

Small field radiotherapy of head and neck cancer patients is responsible for oxidatively damaged DNA/oxidative stress on the level of a whole organism

scientific article published in October 2008

Substantial decrease of urinary 8-oxo-7,8-dihydroguanine, a product of the base excision repair pathway, in DNA glycosylase defective mice

scientific article

Supplementation with antioxidant vitamins prevents oxidative modification of DNA in lymphocytes of HIV-infected patients

scientific article published in March 2002

Systemic oxidoreductive balance and vascular function in individuals without clinical manifestation of atherosclerosis

scientific article published on 05 October 2017

Systemowa równowaga antyoksyacyjna u pacjentów bez klinicznej manifestacji miażdżycy

scientific article published on 12 April 2018

Targeted DNA oxidation by LSD1-SMAD2/3 primes TGF-β1/ EMT genes for activation or repression

scientific article published on 22 July 2020

The Membrane Electrical Potential and Intracellular pH as Factors Influencing Intracellular Ascorbate Concentration and Their Role in Cancer Treatment

scientific article published on 30 October 2021

The level of 8-hydroxyguanine, a possible repair product of oxidative DNA damage, is higher in urine of cancer patients than in control subjects

scientific article published in October 2002

The level of 8-oxo-7,8-dihydro-2'-deoxyguanosine is positively correlated with the size of the labile iron pool in human lymphocytes

scientific article

The level of active DNA demethylation compounds in leukocytes and urine samples as potential epigenetic biomarkers in breast cancer patients

scientific article published on 18 March 2024

The relationship between 8-oxo-7,8-dihydro-2'-deoxyguanosine level and extent of cytosine methylation in leukocytes DNA of healthy subjects and in patients with colon adenomas and carcinomas

scientific article

The urinary excretion of epigenetically modified DNA as a marker of pediatric ALL status and chemotherapy response

scientific article published in November 2021

Tissue-Specific Differences in DNA Modifications (5-Hydroxymethylcytosine, 5-Formylcytosine, 5-Carboxylcytosine and 5-Hydroxymethyluracil) and Their Interrelationships

scientific article published on 14 December 2015

Urinary 5-hydroxymethyluracil and 8-oxo-7,8-dihydroguanine as potential biomarkers in patients with colorectal cancer

scientific article published on 31 July 2015

Urinary Measurement of Epigenetic DNA Modifications: A Non-Invasive Assessment of the Whole-Body Epigenetic Status in Healthy Subjects and Colorectal Cancer Patients.

scientific article

Urinary excretion rates of 8-oxoGua and 8-oxodG and antioxidant vitamins level as a measure of oxidative status in healthy, full-term newborns

scientific article published on 01 September 2007

Urinary measurement of 8-OxodG, 8-OxoGua, and 5HMUra: a noninvasive assessment of oxidative damage to DNA.

scientific article published in May 2006

Viral infection-oxidative stress/DNA damage-aberrant DNA methylation: separate or interrelated events responsible for genetic instability and childhood ALL development?

scientific article published on 05 July 2014

Vitamin C enhances substantially formation of 5-hydroxymethyluracil in cellular DNA.

scientific article published on 7 November 2016

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