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List of works by Rob J Vandebriel

A comparison of immunotoxic effects of nanomedicinal products with regulatory immunotoxicity testing requirements

scientific article

A helper T-cell epitope of the E7 protein of human papillomavirus type 16 in BALB/c mice

scientific article published on 01 June 1995

A methodology for developing key events to advance nanomaterial-relevant adverse outcome pathways to inform risk assessment

journal article published in 2021

A practical approach to assess inhalation toxicity of metal oxide nanoparticles in vitro

scientific article published on 28 September 2017

A quantitative method for assessing the sensitizing potency of low molecular weight chemicals using a local lymph node assay: employment of a regression method that includes determination of the uncertainty margins.

scientific article published in April 2000

A review of mammalian toxicity of ZnO nanoparticles

scientific article

Airborne particulate matter from goat farm increases acute allergic airway responses in mice

scientific article published on 22 June 2020

Altered cytokine (receptor) mRNA expression as a tool in immunotoxicology

scientific article published on 01 September 1998

An European inter-laboratory validation of alternative endpoints of the murine local lymph node assay: 2nd round

scientific article published on 12 February 2005

Angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers and the risk of developing rheumatoid arthritis in antihypertensive drug users

scientific article published on 06 June 2012

Assessment of preferential T-helper 1 or T-helper 2 induction by low molecular weight compounds using the local lymph node assay in conjunction with RT-PCR and ELISA for interferon-gamma and interleukin-4

scientific article

Association between statin use and lupus-like syndrome using spontaneous reports

scientific article published on 24 August 2011

Association of Bordetella pertussis with host immune cells in the mouse lung

scientific article published on 01 July 2003

Comparative gene expression profiling in two congenic mouse strains following Bordetella pertussis infection.

scientific article

Comparison of dose-responses of contact allergens using the guinea pig maximization test and the local lymph node assay.

scientific article

Comparison of the molecular topologies of stress-activated transcription factors HSF1, AP-1, NRF2, and NF-κB in their induction kinetics of HMOX1.

scientific article published on 6 September 2014

Consequences of the expression of lipopolysaccharide-modifying enzymes for the efficacy and reactogenicity of whole-cell pertussis vaccines

scientific article published on 17 May 2007

Considerations for Safe Innovation: The Case of Graphene.

scientific article published on 21 September 2017

Dendritic cell-based in vitro assays for vaccine immunogenicity ⬇️

scientific article published on September 1, 2012

Detection of immunotoxicity using T-cell based cytokine reporter cell lines ("Cell Chip").

scientific article

Determination of the sensitising activity of the rubber contact sensitisers TMTD, ZDMC, MBT and DEA in a modified local lymph node assay and the effect of sodium dodecyl sulfate pretreatment on local lymph node responses.

scientific article

Development of the "Cell Chip": a new in vitro alternative technique for immunotoxicity testing.

scientific article

Distribution, elimination, and toxicity of silver nanoparticles and silver ions in rats after 28-day oral exposure.

scientific article published on 9 August 2012

Drivers and barriers in the consistency approach for vaccine batch release testing: Report of an international workshop

scientific article published on 27 June 2017

Effects of a diphtheria-tetanus-acellular pertussis vaccine on immune responses in murine local lymph node and lung allergy models

scientific article published on 3 January 2007

Effects of in vivo exposure to bis(tri-n-butyltin)oxide, hexachlorobenzene, and benzo(a)pyrene on cytokine (receptor) mRNA levels in cultured rat splenocytes and on IL-2 receptor protein levels.

scientific article published on January 1998

Gene polymorphisms within the immune system that may underlie drug allergy ⬇️

scientific article published on October 3, 2003

Horizon scan of nanomedicinal products.

scientific article published on 19 February 2015

Host genetics of Bordetella pertussis infection in mice: significance of Toll-like receptor 4 in genetic susceptibility and pathobiology.

scientific article

Identification of biomarkers to detect residual pertussis toxin using microarray analysis of dendritic cells.

scientific article published on 18 September 2013

Immunotoxicology: A brief history, current status and strategies for future immunotoxicity assessment

scientific article published on 01 August 2017

Impact of exposure duration by low molecular weight compounds on interferon-gamma and interleukin-4 mRNA expression and production in the draining lymph nodes of mice.

scientific article published in June 2003

In vitro exposure effects of cyclosporin A and bis(tri-n-butyltin)oxide on lymphocyte proliferation, cytokine (receptor) mRNA expression, and cell surface marker expression in rat thymocytes and splenocytes

scientific article

In vitro immunotoxicity of bis(tri-n-butyltin)oxide (TBTO) studied by toxicogenomics

scientific article published on 05 May 2007

In vitro innate immune cell based models to assess whole cell Bordetella pertussis vaccine quality: a proof of principle

scientific article

Initial immunochemical characterization of specific macrophage-arming factor

scientific article published on 01 January 1989

Keratinocyte gene expression profiles discriminate sensitizing and irritating compounds.

scientific article published on 20 June 2010

Lung pathology and immediate hypersensitivity in a mouse model after vaccination with pertussis vaccines and challenge with Bordetella pertussis

scientific article published on 12 December 2006

Lung response to Bordetella pertussis infection in mice identified by gene-expression profiling

scientific article published on 9 May 2007

Nanomedicinal products: a survey on specific toxicity and side effects

scientific article published on 22 August 2017

Nonclinical regulatory immunotoxicity testing of nanomedicinal products: Proposed strategy and possible pitfalls ⬇️

scientific article published on 07 April 2020

Pattern of risks of rheumatoid arthritis among patients using statins: A cohort study with the clinical practice research datalink

scientific article published on 23 February 2018

Pattern of risks of systemic lupus erythematosus among statin users: a population-based cohort study

scientific article

Respiratory sensitization: advances in assessing the risk of respiratory inflammation and irritation.

scientific article published on 05 May 2011

Response of MUTZ-3 dendritic cells to the different components of the Haemophilus influenzae type B conjugate vaccine: towards an in vitro assay for vaccine immunogenicity.

scientific article published on 30 May 2011

Response to 'Statins accelerate the onset of collagen type II-induced arthritis in mice'-authors' reply ⬇️

scientific article published on March 8, 2013

Risk assessment of titanium dioxide nanoparticles via oral exposure, including toxicokinetic considerations.

scientific article published on 29 September 2016

Specific T-cell factor production and lymphocytes in the direct surroundings of a subcutaneous allogeneic tumor

scientific article published on October 15, 1992

Specific T-cell factors that initiate cellular immune responses are produced by CD4-, CD8-, V beta 8- lymphocytes and are present in nude mice

State of the art in non-animal approaches for skin sensitization testing: from individual test methods towards testing strategies

scientific article published on 14 September 2016

Statin use and markers of immunity in the Doetinchem cohort study

scientific article

Statin-associated polymyalgia rheumatica. An analysis using WHO global individual case safety database: a case/non-case approach

scientific article

Statins accelerate the onset of collagen type II-induced arthritis in mice ⬇️

scientific article published on April 26, 2012

Strategies for the optimisation of in vivo experiments in accordance with the 3Rs philosophy.

scientific article

Sub-chronic toxicity study in rats orally exposed to nanostructured silica.

scientific article published on 7 February 2014

The crystal structure of titanium dioxide nanoparticles influences immune activity in vitro and in vivo

scientific article published on 30 January 2018

The effect of zirconium doping of cerium dioxide nanoparticles on pulmonary and cardiovascular toxicity and biodistribution in mice after inhalation.

scientific article published on 25 July 2017

Toward a mechanism-based in vitro safety test for pertussis toxin

scientific article

Towards a nanospecific approach for risk assessment

scientific article published on 30 May 2016

Toxicogenomics in the assessment of immunotoxicity.

scientific article published on January 2007

UVB exposure-induced systemic modulation of Th1- and Th2-mediated immune responses

scientific article published on 01 July 1999

Use of statins is associated with an increased risk of rheumatoid arthritis

scientific article published on 06 October 2011

Vaccine-induced antibody responses as parameters of the influence of endogenous and environmental factors

scientific article

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