Advanced search

Authors whose works are in public domain in at least one jurisdiction

List of works by Gaël Roué

1-50 of 69 results

View this query on the Wikidata Query Service
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article
The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status

scientific article published on 15 September 2005
Landscape of somatic mutations and clonal evolution in mantle cell lymphoma.

scientific article published on 21 October 2013
The BH3-mimetic GX15-070 synergizes with bortezomib in mantle cell lymphoma by enhancing Noxa-mediated activation of Bak

scientific article published on 16 January 2007
SOX11 regulates PAX5 expression and blocks terminal B-cell differentiation in aggressive mantle cell lymphoma

scientific article published on 15 January 2013
Drp1 mediates caspase-independent type III cell death in normal and leukemic cells

scientific article published on 6 August 2007
BCL-2 phosphorylation modulates sensitivity to the BH3 mimetic GX15-070 (Obatoclax) and reduces its synergistic interaction with bortezomib in chronic lymphocytic leukemia cells.

scientific article published on 3 July 2008
The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78

scientific article published on 24 November 2010
The EMT activator ZEB1 promotes tumor growth and determines differential response to chemotherapy in mantle cell lymphoma

scientific article
Bendamustine is effective in p53-deficient B-cell neoplasms and requires oxidative stress and caspase-independent signaling

scientific article
Vorinostat-induced apoptosis in mantle cell lymphoma is mediated by acetylation of proapoptotic BH3-only gene promoters

scientific article published on 7 June 2011
Selective Inhibition of I B Kinase Sensitizes Mantle Cell Lymphoma B Cells to TRAIL by Decreasing Cellular FLIP Level

scientific article published on 01 February 2007
Synergistic antitumor activity of lenalidomide with the BET bromodomain inhibitor CPI203 in bortezomib-resistant mantle cell lymphoma

scientific article
The γ-secretase inhibitor PF-03084014 combined with fludarabine antagonizes migration, invasion and angiogenesis in NOTCH1-mutated CLL cells

scientific article published on 30 April 2014
Counteracting autophagy overcomes resistance to everolimus in mantle cell lymphoma

scientific article
In vitro and In vivo selective antitumor activity of Edelfosine against mantle cell lymphoma and chronic lymphocytic leukemia involving lipid rafts

scientific article published on 16 March 2010
The expression of the endoplasmic reticulum stress sensor BiP/GRP78 predicts response to chemotherapy and determines the efficacy of proteasome inhibitors in diffuse large b-cell lymphoma

scientific article
A dual role of IFN-alpha in the balance between proliferation and death of human CD4+ T lymphocytes during primary response

scientific article published on 01 September 2004
The phosphatidylinositol-3-kinase inhibitor NVP-BKM120 overcomes resistance signals derived from microenvironment by regulating the Akt/FoxO3a/Bim axis in chronic lymphocytic leukemia cells

scientific article published on 12 July 2013
Lipid raft-mediated Akt signaling as a therapeutic target in mantle cell lymphoma

scientific article published on May 31, 2013
Mitochondrial dysfunction in CD47-mediated caspase-independent cell death: ROS production in the absence of cytochrome c and AIF release

scientific article published in August 2003
Dual PI3K/mTOR inhibition is required to effectively impair microenvironment survival signals in mantle cell lymphoma.

scientific article published on August 2014
p65 activity and ZAP-70 status predict the sensitivity of chronic lymphocytic leukemia cells to the selective IkappaB kinase inhibitor BMS-345541.

scientific article
The BET bromodomain inhibitor CPI203 overcomes resistance to ABT-199 (venetoclax) by downregulation of BFL-1/A1 in in vitro and in vivo models of MYC+/BCL2+ double hit lymphoma.

scientific article published on 22 January 2018
Caspase-independent type III programmed cell death in chronic lymphocytic leukemia: the key role of the F-actin cytoskeleton

scientific article published on 10 March 2009
Antitumoral activity of lenalidomide in in vitro and in vivo models of mantle cell lymphoma involves the destabilization of cyclin D1/p27KIP1 complexes

scientific article published on 31 October 2013
Expression of dengue ApoptoM sequence results in disruption of mitochondrial potential and caspase activation.

scientific article published on August 2003
Sorafenib inhibits cell migration and stroma-mediated bortezomib resistance by interfering B-cell receptor signaling and protein translation in mantle cell lymphoma

scientific article published on 11 December 2012
Synergistic anti-tumor activity of acadesine (AICAR) in combination with the anti-CD20 monoclonal antibody rituximab in in vivo and in vitro models of mantle cell lymphoma

scientific article published on February 2014
Annonaceous acetogenins: the hydroxyl groups and THF rings are crucial structural elements for targeting the mitochondria, demonstration with the synthesis of fluorescent squamocin analogues.

scientific article published in June 2005
Plasmablastic transformation of low-grade B-cell lymphomas: report on 6 cases

scientific article published in February 2013
Update on the molecular pathogenesis and clinical treatment of mantle cell lymphoma: report of the 10th annual conference of the European Mantle Cell Lymphoma Network

scientific article published on 18 August 2011
In vivo intratumoral Epstein-Barr virus replication is associated with XBP1 activation and early-onset post-transplant lymphoproliferative disorders with prognostic implications.

scientific article published on 25 April 2014
Targeting the ubiquitin proteasome system: beyond proteasome inhibition.

scientific article published on January 2013
ZEB1-induced tumourigenesis requires senescence inhibition via activation of DKK1/mutant p53/Mdm2/CtBP and repression of macroH2A1.

scientific article published on 13 December 2016
Autophagy controls everolimus (RAD001) activity in mantle cell lymphoma

scientific article published on 18 October 2012
The Human CD38 Monoclonal Antibody Daratumumab Shows Antitumor Activity and Hampers Leukemia-Microenvironment Interactions in Chronic Lymphocytic Leukemia.

scientific article published on 16 September 2016
Disruption of follicular dendritic cells-follicular lymphoma cross-talk by the pan-PI3K inhibitor BKM120 (Buparlisib).

scientific article published on 5 May 2014
Cytoplasmic cyclin D1 controls the migration and invasiveness of mantle lymphoma cells.

scientific article published on 24 October 2017
Sorafenib targets BCR kinases and blocks migratory and microenvironmental survival signals in CLL cells.

scientific article published on 20 December 2011
The BET bromodomain inhibitor CPI203 improves lenalidomide and dexamethasone activity in in vitro and in vivo models of multiple myeloma by blockade of Ikaros and MYC signaling.

scientific article
B cell activation through CD40 and IL4R ligation modulates the response of chronic lymphocytic leukaemia cells to BAFF and APRIL.

scientific article
Ectopic expression of cyclin D1 impairs the proliferation and enhances the apoptosis of a murine lymphoid cell line.

scientific article published on January 2001
Caspase-independent type III PCD: a new means to modulate cell death in chronic lymphocytic leukemia

scientific article
Upstream mediators of the Fas apoptotic transduction pathway are defective in B-chronic lymphocytic leukemia.

scientific article
Expression of cyclins D-type in B-chronic lymphoproliferative disorders

scientific article published in July 2000
Bcl-2high mantle cell lymphoma cells are sensitized to acadesine with ABT-199.

scientific article
Activity of the novel BCR kinase inhibitor IQS019 in preclinical models of B-cell non-Hodgkin lymphoma

scientific article published on 31 March 2017
Combined analysis of levels of serum B-cell activating factor and a proliferation-inducing ligand as predictor of disease progression in patients with chronic lymphocytic leukemia

scientific article
Pharmacological modulation of CXCR4 cooperates with BET bromodomain inhibition in diffuse large B-cell lymphoma

scientific article published on 28 June 2018

Paulina is supported by:

About Paulina

Help