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List of works by Seth Darst

Climate change and the integrity of science

scientific article

Crystal structure of Aquifex aeolicus σN bound to promoter DNA and the structure of σN-holoenzyme.

scientific article published on 21 February 2017

E. coli TraR allosterically regulates transcription initiation by altering RNA polymerase conformation

scientific article published on 16 December 2019

Fidaxomicin jams Mycobacterium tuberculosis RNA polymerase motions needed for initiation via RbpA contacts.

scientific article published on 26 February 2018

RNA polymerase motions during promoter melting.

scientific article published on May 2017

Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex

scientific article published on 13 July 2020

Structural basis for transcription activation by Crl through tethering of σS and RNA polymerase

scientific article published on 04 September 2019

Structural basis of transcription arrest by coliphage HK022 Nun in an Escherichia coli RNA polymerase elongation complex.

scientific article published on 20 March 2017

Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin

article published in the Proceedings of the National Academy of Sciences of the United States of America

Structure and function of the mycobacterial transcription initiation complex with the essential regulator RbpA.

scientific article published on 09 January 2017

The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase

scientific article published on 16 November 2020

Time-resolved cryo-EM using Spotiton

scientific article published on 10 August 2020

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