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List of works by Andreas Weigert

AXL Inhibition in Macrophages Stimulates Host-versus-Leukemia Immunity and Eradicates Naïve and Treatment-Resistant Leukemia

publication published on 08 June 2021

An in vitro test system for compounds that modulate human inflammatory macrophage polarization

scientific article published on 18 June 2018

Anti-inflammatory role of microsomal prostaglandin E synthase-1 in a model of neuroinflammation.

scientific article published on 12 November 2010

Apoptotic Cancer Cells Suppress 5-Lipoxygenase in Tumor-Associated Macrophages

scientific article published on 11 December 2017

Apoptotic Diminution of Immature Single and Double Positive Thymocyte Subpopulations Contributes to Thymus Involution During Murine Polymicrobial Sepsis

scientific article published in August 2017

Apoptotic cells enhance sphingosine‐1‐phosphate receptor 1 dependent macrophage migration ⬇️

scientific article published on August 29, 2013

Apoptotic cells induce arginase II in macrophages, thereby attenuating NO production

scientific article published on 24 April 2007

Apoptotic cells promote macrophage survival by releasing the antiapoptotic mediator sphingosine-1-phosphate.

scientific article published on 11 May 2006

Apoptotic tumor cell-derived microRNA-375 uses CD36 to alter the tumor-associated macrophage phenotype

scientific article published on 08 March 2019

Beyond Immune Cell Migration: The Emerging Role of the Sphingosine-1-phosphate Receptor S1PR4 as a Modulator of Innate Immune Cell Activation

scientific article published on 07 August 2017

Blocking mTOR Signalling with Rapamycin Ameliorates Imiquimod-induced Psoriasis in Mice

scientific article published on 09 June 2017

Cancer cell and macrophage cross-talk in the tumor microenvironment

scientific article

Cancer-induced inflammation and inflammation-induced cancer in colon: a role for S1P lyase

scientific article published on 28 February 2019

Cellular analysis of the histamine H4 receptor in human myeloid cells

scientific article published on 13 January 2016

Ceramide Synthase 5 Deficiency Aggravates Dextran Sodium Sulfate-Induced Colitis and Colon Carcinogenesis and Impairs T-Cell Activation

scientific article published on 01 July 2020

Ceramide synthase 2 deficiency aggravates AOM-DSS-induced colitis in mice: role of colon barrier integrity.

scientific article published on 12 April 2017

Characterization of RA839, a Noncovalent Small Molecule Binder to Keap1 and Selective Activator of Nrf2 Signaling

scientific article published on 12 October 2015

Cleavage of sphingosine kinase 2 by caspase-1 provokes its release from apoptotic cells.

scientific article published on 2 March 2010

Dedicated immunosensing of the mouse intestinal epithelium facilitated by a pair of genetically coupled lectin-like receptors

scientific article

Depletion of tristetraprolin in breast cancer cells increases interleukin-16 expression and promotes tumor infiltration with monocytes/macrophages ⬇️

scientific article published on December 14, 2012

Downregulation of BTLA on NKT Cells Promotes Tumor Immune Control in a Mouse Model of Mammary Carcinoma.

scientific article published on 7 March 2018

Endo-PDI is required for TNFα-induced angiogenesis

scientific article

Fibroblast Growth Factor-14 Acts as Tumor Suppressor in Lung Adenocarcinomas

scientific article published on 22 July 2020

Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system

scientific article published in 2022

GM-CSF in murine psoriasiform dermatitis: Redundant and pathogenic roles uncovered by antibody-induced neutralization and genetic deficiency.

scientific article

HIF-1α is a negative regulator of plasmacytoid DC development in vitro and in vivo

scientific article published on 30 August 2012

HVEM, a cosignaling molecular switch, and its interactions with BTLA, CD160 and LIGHT

scientific article published on 03 June 2019

Heme oxygenase-1 contributes to an alternative macrophage activation profile induced by apoptotic cell supernatants.

scientific article published on 7 January 2009

Histone Deacetylation Inhibitors as Modulators of Regulatory T Cells

scientific article published on 29 March 2020

Hypoxia Causes Downregulation of Dicer in Hepatocellular Carcinoma, Which Is Required for Upregulation of Hypoxia-Inducible Factor 1α and Epithelial-Mesenchymal Transition

scientific article published on 6 February 2017

Hypoxia Potentiates Palmitate-induced Pro-inflammatory Activation of Primary Human Macrophages

scientific article

Hypoxia enhances sphingosine kinase 2 activity and provokes sphingosine-1-phosphate-mediated chemoresistance in A549 lung cancer cells.

scientific article

Hypoxia stimulus: An adaptive immune response during dendritic cell maturation.

scientific article published on 23 January 2008

IL-1 family cytokines in cancer immunity - a matter of life and death

scientific article

IL-38 Ameliorates Skin Inflammation and Limits IL-17 Production from γδ T Cells

scientific article published on 01 April 2019

IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors

scientific article published on 30 July 2018

Identification of IRF1 as critical dual regulator of Smac mimetic-induced apoptosis and inflammatory cytokine response

scientific article published on 11 December 2014

Identification of tumor-associated macrophage subsets that are associated with breast cancer prognosis

scientific article published on 01 December 2020

Immune and Inflammatory Cell Composition of Human Lung Cancer Stroma

scientific article published on 28 September 2015

Inflammation-induced loss of Pdcd4 is mediated by phosphorylation-dependent degradation

scientific article

Inhibition of GTP cyclohydrolase attenuates tumor growth by reducing angiogenesis and M2-like polarization of tumor associated macrophages.

scientific article

Inhibition of GTP cyclohydrolase reduces cancer pain in mice and enhances analgesic effects of morphine

scientific article published on 17 June 2012

Interleukin-10-induced neutrophil gelatinase-associated lipocalin production in macrophages with consequences for tumor growth.

scientific article

Interleukin-38 is released from apoptotic cells to limit inflammatory macrophage responses

scientific article published on 17 February 2016

Killing Is Not Enough: How Apoptosis Hijacks Tumor-Associated Macrophages to Promote Cancer Progression

scientific article published in January 2016

Knockout of HIF-1α in tumor-associated macrophages enhances M2 polarization and attenuates their pro-angiogenic responses

scientific article

L-type calcium channel inhibitor diltiazem prevents aneurysm formation by blood pressure-independent anti-inflammatory effects.

scientific article published on 30 September 2013

Lipocalin 2 from macrophages stimulated by tumor cell-derived sphingosine 1-phosphate promotes lymphangiogenesis and tumor metastasis

scientific article published on 28 June 2016

Loss of Nrf2 in bone marrow-derived macrophages impairs antigen-driven CD8(+) T cell function by limiting GSH and Cys availability.

scientific article

Lung cancer-associated pulmonary hypertension: Role of microenvironmental inflammation based on tumor cell-immune cell cross-talk

scientific article

Macrophage NOS2 in Tumor Leukocytes

scientific article published on 9 July 2016

Macrophage Polarization In The Tumor Microenvironment

scientific article

Macrophage S1PR1 Signaling Alters Angiogenesis and Lymphangiogenesis During Skin Inflammation

scientific article published on 28 July 2019

Macrophage and cancer cell cross-talk via CCR2 and CX3CR1 is a fundamental mechanism driving lung cancer

scientific article published on February 2015

Macrophage-derived lipocalin-2 transports iron in the tumor microenvironment

scientific article published on 22 December 2017

Macrophages attenuate the transcription of CYP1A1 in breast tumor cells and enhance their proliferation

scientific article published in PLoS ONE

Macrophages programmed by apoptotic cells promote angiogenesis via prostaglandin E2.

scientific article published on 30 March 2011

Metastasis-associated protein 2 represses NF-ƙB to reduce lung tumor growth and inflammation

scientific article published on 14 August 2020

Microenvironmental Th9- and Th17- lymphocytes induce metastatic spreading in lung cancer

scientific article published on 31 March 2020

Myeloid-Specific Deletion of the AMPKα2 Subunit Alters Monocyte Protein Expression and Atherogenesis

scientific article published on 19 June 2019

Necrosis in DU145 prostate cancer spheroids induces COX‐2/mPGES‐1‐derived PGE2 to promote tumor growth and to inhibit T cell activation ⬇️

scientific article published on April 22, 2013

Neuromediators in inflammation--a macrophage/nerve connection.

scientific article published on 04 June 2010

Nitric oxide maintains endothelial redox homeostasis through PKM2 inhibition

scientific article published on 22 July 2019

Nitric oxide, apoptosis and macrophage polarization during tumor progression.

scientific article published on 29 April 2008

Nox2-dependent signaling between macrophages and sensory neurons contributes to neuropathic pain hypersensitivity

scientific article published on 17 August 2014

NoxO1 Controls Proliferation of Colon Epithelial Cells.

scientific article

PGE2 in fibrosis and cancer: Insights into fibroblast activation

scientific article published on 14 May 2019

PGE2/EP4 signaling in peripheral immune cells promotes development of experimental autoimmune encephalomyelitis

scientific article published on 16 December 2013

PPARgamma1 attenuates cytosol to membrane translocation of PKCalpha to desensitize monocytes/macrophages.

scientific article

RNAi screen in apoptotic cancer cell-stimulated human macrophages reveals co-regulation of IL-6/IL-10 expression

scientific article published on 2 February 2012

Redirecting tumor-associated macrophages to become tumoricidal effectors as a novel strategy for cancer therapy

scientific article published on 12 April 2017

Redox control of inflammation in macrophages

scientific article published on 06 March 2013

Redox-signals and macrophage biology (for the upcoming issue of molecular aspects of medicine on signaling by reactive oxygen species).

scientific article published on 9 January 2018

Regulation of macrophage function by sphingosine-1-phosphate.

scientific article published on 21 July 2009

Reprogramming of tumor-associated macrophages by targeting β-catenin/FOSL2/ARID5A signaling: A potential treatment of lung cancer

scientific article published on 05 June 2020

Response to Sympathoinhibitory Effect of Diltiazem and Prevention of Aneurysm Formation

scientific article published on 01 March 2014

Response to letter regarding article, "Vitamin D promotes vascular regeneration".

scientific article published in June 2015

Resveratrol-induced potentiation of the antitumor effects of oxaliplatin is accompanied by an altered cytokine profile of human monocyte-derived macrophages

scientific article published on 9 April 2014

S1P Provokes Tumor Lymphangiogenesis via Macrophage-Derived Mediators Such as IL-1β or Lipocalin-2.

scientific article published on 19 July 2017

S1PR1 on tumor-associated macrophages promotes lymphangiogenesis and metastasis via NLRP3/IL-1β.

scientific article published on 24 July 2017

S1PR4 Signaling Attenuates ILT 7 Internalization To Limit IFN-α Production by Human Plasmacytoid Dendritic Cells.

scientific article

S1PR4 is required for plasmacytoid dendritic cell differentiation

scientific article published on June 2015

S1PR4-dependent CCL2 production promotes macrophage recruitment in a murine psoriasis model

scientific article published on 04 February 2020

Smac Mimetic-Induced Upregulation of CCL2/MCP-1 Triggers Migration and Invasion of Glioblastoma Cells and Influences the Tumor Microenvironment in a Paracrine Manner

scientific article published on June 2015

Smac mimetic and glucocorticoids synergize to induce apoptosis in childhood ALL by promoting ripoptosome assembly

scientific article published on 22 May 2014

Spatial Density and Distribution of Tumor-Associated Macrophages Predict Survival in Non-Small-Cell Lung Carcinoma

scientific article published on 22 July 2020

Sphingosine Kinases are Involved in Macrophage NLRP3 Inflammasome Transcriptional Induction ⬇️

scientific article published on 02 July 2020

Sphingosine kinase 2 deficient tumor xenografts show impaired growth and fail to polarize macrophages towards an anti-inflammatory phenotype

scientific article

Sphingosine kinase 2 is a negative regulator of inflammatory macrophage activation

scientific article published on 23 May 2019

Sphingosine-1 phosphate promotes thymic atrophy during sepsis progression.

scientific article published on 3 December 2014

Sphingosine-1-Phosphate and Macrophage Biology-How the Sphinx Tames the Big Eater

scientific article published on 19 July 2019

Sphingosine-1-phosphate signalling induces the production of Lcn-2 by macrophages to promote kidney regeneration

scientific article

Sulforaphane potentiates oxaliplatin-induced cell growth inhibition in colorectal cancer cells via induction of different modes of cell death

scientific article published on 6 August 2010

THP-1 and human peripheral blood mononuclear cell-derived macrophages differ in their capacity to polarize in vitro.

scientific article published on 07 June 2017

Technical advance: Generation of human pDC equivalents from primary monocytes using Flt3-L and their functional validation under hypoxia

scientific article published on 18 May 2010

The G2A Receptor Controls Polarization of Macrophage by Determining Their Localization Within the Inflamed Tissue

scientific article published on 01 October 2018

The Lipid Receptor G2A (GPR132) Mediates Macrophage Migration in Nerve Injury-Induced Neuropathic Pain

scientific article published on 21 July 2020

The NADPH Oxidase Nox4 Controls Macrophage Polarization in an NFκB-Dependent Manner

scientific article published on 18 April 2019

The NADPH organizers NoxO1 and p47phox are both mediators of diabetes-induced vascular dysfunction in mice

scientific article

The RNA-binding protein HuR inhibits expression of CCL5 and limits recruitment of macrophages into tumors

scientific article published on 21 July 2017

The Specific IKKε/TBK1 Inhibitor Amlexanox Suppresses Human Melanoma by the Inhibition of Autophagy, NF-κB and MAP Kinase Pathways ⬇️

scientific article published on 02 July 2020

The histone demethylase PHF8 facilitates alternative splicing of the histocompatibility antigen HLA-G

scientific article published on 27 February 2019

The liaison between apoptotic cells and macrophages--the end programs the beginning.

scientific article published on May 2009

The multi-faceted roles of prostaglandin E2 in cancer-infiltrating mononuclear phagocyte biology.

scientific article published on 11 May 2012

The portal vein as a distinct immunological compartment - A comprehensive immune phenotyping study

scientific article published on 30 July 2018

The prostaglandin E2 receptor EP3 controls CC-chemokine ligand 2-mediated neuropathic pain induced by mechanical nerve damage.

scientific article published on 11 May 2018

The role of TRKA signaling in IL-10 production by apoptotic tumor cell-activated macrophages

scientific article published on 12 March 2012

The supernatant of apoptotic cells causes transcriptional activation of hypoxia-inducible factor-1alpha in macrophages via sphingosine-1-phosphate and transforming growth factor-beta.

scientific article published on 23 June 2009

Tolerizing CTL by Sustained Hepatic PD-L1 Expression Provides a New Therapy Approach in Mouse Sepsis

scientific article published on 16 March 2019

Tumor cell apoptosis polarizes macrophages role of sphingosine-1-phosphate.

scientific article

Tumor-associated macrophages as targets for tumor immunotherapy.

scientific article published on January 2009

Tumour stroma-derived lipocalin-2 promotes breast cancer metastasis.

scientific article published on April 2016

VASP regulates leukocyte infiltration, polarization, and vascular repair after ischemia.

scientific article published on 5 March 2018

Vitamin D promotes vascular regeneration

scientific article published on 11 July 2014

mPGES-1 and ALOX5/-15 in tumor-associated macrophages

scientific article published on 01 September 2018

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