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List of works by Jan Bakker

A National Multicenter Trial on Family Presence During Brain Death Determination: The FABRA Study ⬇️

scientific article published on October 1, 2012

A novel approach to assess hemorrhagic shock severity using the arterially determined left ventricular isovolumic contraction period

scientific article published on 15 December 2013

A novel mortality risk score predicting intensive care mortality in cardiogenic shock patients treated with veno-arterial extracorporeal membrane oxygenation

scientific article published on 09 October 2019

A systematic review of implementation strategies for assessment, prevention, and management of ICU delirium and their effect on clinical outcomes

scientific article

Accidental methanol ingestion: case report

scientific article

Acidosis predicts mortality independently from hyperlactatemia in patients with sepsis

scientific article published on 03 March 2020

Acute folate deficiency in a critically ill patient

scientific article

Alternatives to the Swan–Ganz catheter

scientific article published on 03 May 2018

An Observational Study on a Protocol for Withdrawal of Life-Sustaining Measures on Two Non-Academic Intensive Care Units in The Netherlands: Few Signs of Distress, No Suffering?

scientific article published on 31 August 2015

Assessment of tissue oxygen saturation during a vascular occlusion test using near-infrared spectroscopy: the role of probe spacing and measurement site studied in healthy volunteers.

scientific article

Bedside measurement of changes in lung impedance to monitor alveolar ventilation in dependent and non-dependent parts by electrical impedance tomography during a positive end-expiratory pressure trial in mechanically ventilated intensive care [...]

scientific article

Biomarkers for the prediction of acute kidney injury: a narrative review on current status and future challenges.

scientific article published on April 2012

Bis maltolato oxovanadium (BMOV) and ischemia/reperfusion-induced acute kidney injury in rats

scientific article published on 27 February 2014

Capillary refill time during fluid resuscitation in patients with sepsis-related hyperlactatemia at the emergency department is related to mortality.

scientific article published on 27 November 2017

Capillary refill time status could identify different clinical phenotypes among septic shock patients fulfilling Sepsis-3 criteria: a post hoc analysis of ANDROMEDA-SHOCK trial

scientific article published on 19 February 2020

Capillary refill time: the missing link between macrocirculation and microcirculation in septic shock?

scientific article published on 01 March 2020

Changes in peripheral perfusion relate to visceral organ perfusion in early septic shock: A pilot study

scientific article published on 12 May 2016

Clinical assessment of peripheral circulation

scientific article published on June 2015

Clinical assessment of peripheral perfusion to predict postoperative complications after major abdominal surgery early: a prospective observational study in adults

scientific article

Clinical monitoring of peripheral perfusion: there is more to learn

scientific article

Clinical review: Clinical imaging of the sublingual microcirculation in the critically ill--where do we stand?

scientific article published on 19 June 2012

Clinical use of lactate monitoring in critically ill patients.

scientific article

Clinical validation of a computerized algorithm to determine mean systemic filling pressure

scientific article published on 31 March 2021

Colistin for the treatment of ventilator-associated pneumonia caused by multidrug-resistant Gram-negative bacteria: a systematic review and meta-analysis.

scientific article published on 10 August 2014

Colistin, SDD and resistance: nihil novi sub sole.

scientific article published on 27 May 2014

Conceptual issues specifically related to health-related quality of life in critically ill patients.

scientific article published on 19 February 2009

Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine.

scientific article

Control of Confounding and Reporting of Results in Causal Inference Studies: Guidance for Authors from Editors of Respiratory, Sleep, and Critical Care Journals

Correction to: Fluid administration for acute circulatory dysfunction using basic monitoring: narrative review and expert panel recommendations from an ESICM task force

scientific article published on 01 January 2019

Cost-consequence analysis of remifentanil-based analgo-sedation vs. conventional analgesia and sedation for patients on mechanical ventilation in the Netherlands ⬇️

scientific article published on January 1, 2010

Counterbalancing work-related stress? Work engagement among intensive care professionals.

scientific article

Current use of vasopressors in septic shock

scientific article published on 30 January 2019

Development of a clinical data warehouse from an intensive care clinical information system.

scientific article

Direct cost analysis of intensive care unit stay in four European countries: applying a standardized costing methodology.

scientific article published in January 2012

Donor conversion rates depend on the assessment tools used in the evaluation of potential organ donors

scientific article

Drotrecogin alfa (activated) in the treatment of severe sepsis patients with multiple-organ dysfunction: data from the PROWESS trial

scientific article

Early Circulating Lactate and Glucose Levels After Aneurysmal Subarachnoid Hemorrhage Correlate With Poor Outcome and Delayed Cerebral Ischemia: A Two-Center Cohort Study.

scientific article

Early lactate clearance-guided therapy in patients with sepsis: a meta-analysis with trial sequential analysis of randomized controlled trials

scientific article published on 08 July 2015

Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial.

scientific article published on 12 May 2010

Early peripheral perfusion-guided fluid therapy in patients with septic shock.

scientific article published in February 2015

Early rise in central venous pressure during a spontaneous breathing trial: A promising test to identify patients at high risk of weaning failure?

scientific article published on 05 December 2019

Effects of a Resuscitation Strategy Targeting Peripheral Perfusion Status versus Serum Lactate Levels among Patients with Septic Shock. A Bayesian Reanalysis of the ANDROMEDA-SHOCK Trial

scientific article published on 01 February 2020

Effects of capillary refill time-vs. lactate-targeted fluid resuscitation on regional, microcirculatory and hypoxia-related perfusion parameters in septic shock: a randomized controlled trial

scientific article published on 02 November 2020

Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock.

scientific article published on 2 August 2016

Electrical impedance tomography measured at two thoracic levels can visualize the ventilation distribution changes at the bedside during a decremental positive end-expiratory lung pressure trial.

scientific article

Endotracheal suctioning with nonsterile gloves and only when necessary!

scientific article published on 11 June 2015

Enhanced paracetamol clearance with molecular adsorbents recirculating system (MARS®) in severe autointoxication.

scientific article published on 12 August 2010

Evaluation of 7.5 years of Surviving Sepsis Campaign Guidelines

scientific article published on 29 October 2014

External validation of a prognostic model predicting time of death after withdrawal of life support in neurocritical patients.

scientific article published in January 2012

Extreme blood pressure oscillations in a patient with a MEN-2a syndrome

scientific article published on 16 January 2014

Failure to wean caused by cryptogenic fibrosing pleuritis and bilateral lung trapping: case report

scientific article published on 01 December 2007

Fluid administration for acute circulatory dysfunction using basic monitoring: narrative review and expert panel recommendations from an ESICM task force

scientific article published on 19 November 2018

Fluid resuscitation in ICU patients: quo vadis?

scientific article published on 14 June 2015

Focus on acute circulatory failure

scientific article published on 21 October 2016

Functional status after intensive care

scientific article published on 01 September 2009

Gain-of-function single nucleotide variants of the CYP2C19 gene (CYP2C19*17) can identify subtherapeutic voriconazole concentrations in critically ill patients: a case series

scientific article published on 04 August 2015

Hastening death due to administration of sedatives and opioids after withdrawal of life-sustaining measures: even in the absence of discomfort?

scientific article published on 18 February 2014

Health-related quality of life in critically ill patients: how to score and what is the clinical impact?

scientific article published on October 2009

Hepatosplanchnic circulation in cirrhosis and sepsis

scientific article

Hospitalized patients at risk of dying: an Intensive Care Medicine call for papers.

scientific article published on 22 October 2015

Imminent brain death and brain death are not the same: reply to Verheijde and Rady ⬇️

scientific article published on September 16, 2010

Imminent brain death: point of departure for potential heart-beating organ donor recognition.

scientific article

Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion.

scientific article published on 22 April 2015

Implications of ICU triage decisions on patient mortality: a cost-effectiveness analysis

scientific article published on 9 February 2011

Improved Guideline Adherence and Reduced Brain Dysfunction After a Multicenter Multifaceted Implementation of ICU Delirium Guidelines in 3,930 Patients

scientific article published on 01 March 2019

Improvement of care for ICU patients with delirium by early screening and treatment: study protocol of iDECePTIvE study

scientific article

Inability to obtain deferred consent due to early death in emergency research: effect on validity of clinical trial results

scientific article

Increased Dead Space Ventilation and Refractory Hypercapnia in Patients With Coronavirus Disease 2019: A Potential Marker of Thrombosis in the Pulmonary Vasculature

scientific article published on 17 September 2020

Increasing intensity of selective digestive decontamination dosing does not result in improved clinical outcomes.

scientific article published on 18 November 2016

Infections, antibiotic treatment and mortality in patients admitted to ICUs in countries considered to have high levels of antibiotic resistance compared to those with low levels

scientific article

Inflatable external leg compression prevents orthostatic hypotension in a patient with a traumatic cervical spinal cord injury

scientific article published on September 2013

Inflatable external upper and lower leg compression improves stroke volume and peripheral perfusion during central hypovolemia in healthy volunteers

scientific article published on September 2013

International point prevalence study of Intensive Care Unit transfusion practices-Pilot study in the Netherlands

scientific article published on 26 September 2019

Is organ donation from brain dead donors reaching an inescapable and desirable nadir?

scientific article published on 01 June 2011

Lactate Measurements: A Guide to Therapy or to Quality?

Lactate and microcirculation as suitable targets for hemodynamic optimization in resuscitation of circulatory shock.

scientific article

Lactate is THE target for early resuscitation in sepsis.

scientific article published on April 2017

Lactate levels and hemodynamic coherence in acute circulatory failure.

scientific article published on 10 November 2016

Lactate-guided resuscitation saves lives: we are not sure

scientific article published on 01 February 2016

Lactate: Where Are We Now?

scientific article published on 18 October 2019

Laser speckle imaging identification of increases in cortical microcirculatory blood flow induced by motor activity during awake craniotomy.

scientific article

Lost in translation: on lactate, hypotension, sepsis-induced tissue hypoperfusion, quantitative resuscitation and Surviving Sepsis Campaign bundles

scientific article published on 01 March 2015

Low tissue oxygen saturation at the end of early goal-directed therapy is associated with worse outcome in critically ill patients.

scientific article

Memorable patients: I’ll be dead on Friday ⬇️

scientific article published on February 1, 2013

Metrology part 1: definition of quality criteria

scientific article published on 17 March 2020

Metrology part 2: Procedures for the validation of major measurement quality criteria and measuring instrument properties

scientific article published on 18 March 2020

Microvascular perfusion as a target for fluid resuscitation in experimental circulatory shock.

scientific article published in February 2014

Multiple-center, randomized, placebo-controlled, double-blind study of the nitric oxide synthase inhibitor 546C88: effect on survival in patients with septic shock

scientific article published on January 2004

Narrative review: clinical assessment of peripheral tissue perfusion in septic shock

scientific article published on 13 March 2019

Near-infrared spectroscopy for monitoring peripheral tissue perfusion in critically ill patients

scientific article published on September 1, 2011

Neutrophil Gelatinase-associated Lipocalin at ICU Admission Predicts for Acute Kidney Injury in Adult Patients ⬇️

scientific article published on October 8, 2010

Nitroglycerin reverts clinical manifestations of poor peripheral perfusion in patients with circulatory shock.

scientific article

Noninvasive functional liver blood flow measurement: comparison between bolus dose and steady-state clearance of sorbitol in a small-rodent model.

scientific article published on 25 November 2009

Noninvasive monitoring of peripheral perfusion

scientific article published on 17 September 2005

Norepinephrine, more than a vasopressor

scientific article published on 01 March 2019

Opioid and Benzodiazepine Requirements in Obese Adult Patients Receiving Extracorporeal Membrane Oxygenation

scientific article published on 27 August 2019

Peripheral Perfusion Index Predicts Hypotension during Fluid Withdrawal by Continuous Veno-Venous Hemofiltration in Critically Ill Patients.

scientific article published on 30 June 2015

Peripheral perfusion index as an early predictor for central hypovolemia in awake healthy volunteers.

scientific article published on 9 January 2013

Peripheral vasoconstriction influences thenar oxygen saturation as measured by near-infrared spectroscopy ⬇️

scientific article published on February 14, 2012

Persistent peripheral and microcirculatory perfusion alterations after out-of-hospital cardiac arrest are associated with poor survival.

scientific article published in August 2012

Perspectives on perfusion monitoring in septic shock after the ANDROMEDA-SHOCK trial

scientific article published on 03 November 2019

Physician-Assisted Suicide and Euthanasia in the ICU: A Dialogue on Core Ethical Issues

scientific article published in February 2017

Postural change in volunteers: sympathetic tone determines microvascular response to cardiac preload and output increases.

scientific article published on 18 August 2015

Practical Use of Lactate Levels in the Intensive Care.

scientific article

Prevalence and incidence of severe sepsis in Dutch intensive care units

scientific article

Prognostic relevance of serum lactate kinetics in critically ill patients

scientific article published on 26 November 2018

Prognostic value of blood lactate levels: does the clinical diagnosis at admission matter?

scientific article published in February 2009

Prolonged mechanical ventilation and chronic critical illness

scientific article published on May 2016

Quality of Care for Elderly Patients With Pneumonia

scientific article published on June 24, 1998

Quality of life on admission to the intensive care: can we query the relatives? ⬇️

scientific article published on May 7, 2003

Re-thinking resuscitation: leaving blood pressure cosmetics behind and moving forward to permissive hypotension and a tissue perfusion-based approach

scientific article published on 08 October 2013

Remarkable changes in the choice of timing to discuss organ donation with the relatives of a patient: a study in 228 organ donations in 20 years

scientific article published on 7 October 2011

Risk indicators for acute kidney injury in cardiogenic shock

scientific article published on 10 November 2018

Safety and efficacy of beta-blockers to improve oxygenation in patients on veno-venous ECMO

scientific article published on 27 June 2019

Severe Infections are Common in Thiamine Deficiency and May be Related to Cognitive Outcomes: A Cohort Study of 68 Patients With Wernicke-Korsakoff Syndrome.

scientific article published on 18 June 2016

Single-nucleotide polymorphisms in the Toll-like receptor pathway increase susceptibility to infections in severely injured trauma patients.

scientific article published on March 2013

Standard of usual care defines effectiveness of early goal directed therapy

scientific article published on 01 December 2019

Starling curves and central venous pressure

scientific article

Statistical analysis plan for early goal-directed therapy using a physiological holistic view - the ANDROMEDA-SHOCK: a randomized controlled trial

scientific article published on 30 July 2018

The Eldicus prospective, observational study of triage decision making in European intensive care units: part I--European Intensive Care Admission Triage Scores

scientific article published on 01 January 2012

The Prevalence of Compassion Fatigue and Burnout among Healthcare Professionals in Intensive Care Units: A Systematic Review

scientific article

The Use of Opioids and Sedatives and Time Until Death After Withdrawing Mechanical Ventilation and Vasoactive Drugs in a Dutch Intensive Care Unit ⬇️

scientific article published on February 8, 2011

The brain is not dead when the cortex is dead.

scientific article

The effect of goal-directed therapy on mortality in patients with sepsis - earlier is better: a meta-analysis of randomized controlled trials

scientific article

The prognostic value of the subjective assessment of peripheral perfusion in critically ill patients.

scientific article published in March 2009

The relation of near-infrared spectroscopy with changes in peripheral circulation in critically ill patients.

scientific article published in July 2011

The ten pitfalls of lactate clearance in sepsis.

scientific article published on 12 May 2018

Time-limited trial of intensive care treatment: an overview of current literature

scientific article published on 22 August 2018

Tissue perfusion and oxygenation to monitor fluid responsiveness in critically ill, septic patients after initial resuscitation: a prospective observational study

scientific article published on 20 January 2015

Total and high-affinity corticosteroid-binding globulin depletion in septic shock is associated with mortality

scientific article published on 26 September 2018

Understanding clinical signs of poor tissue perfusion during septic shock.

scientific article published on 4 February 2016

Understanding venous return

scientific article published on 26 June 2014

Urinary Neutrophil Gelatinase-Associated Lipocalin Measured on Admission to the Intensive Care Unit Accurately Discriminates between Sustained and Transient Acute Kidney Injury in Adult Critically Ill Patients ⬇️

scientific article published on August 4, 2011

Vasopressor therapy: not like antibiotics!

scientific article published on 25 April 2016

What's new on the HPA axis?

scientific article published on 8 April 2015

When to stop septic shock resuscitation: clues from a dynamic perfusion monitoring

scientific article

Withdrawal of Life-Sustaining Treatment in a Mixed Intensive Care Unit: Most Common in Patients with Catastropic Brain Injury ⬇️

scientific article published on February 1, 2012

Year in review in Intensive Care Medicine 2013: I. Acute kidney injury, ultrasound, hemodynamics, cardiac arrest, transfusion, neurocritical care, and nutrition.

scientific article published on 13 December 2013

Year in review in Intensive Care Medicine 2013: II. Sedation, invasive and noninvasive ventilation, airways, ARDS, ECMO, family satisfaction, end-of-life care, organ donation, informed consent, safety, hematological issues in critically ill patients

scientific article published on 24 January 2014

Year in review in Intensive Care Medicine 2013: III. Sepsis, infections, respiratory diseases, pediatrics.

scientific article published on 12 February 2014

Year in review in Intensive Care Medicine 2014: II. ARDS, airway management, ventilation, adjuvants in sepsis, hepatic failure, symptoms assessment and management, palliative care and support for families, prognostication, organ donation, outcome, o

scientific article published on 25 February 2015

Year in review in Intensive Care Medicine 2014: III. Severe infections, septic shock, healthcare-associated infections, highly resistant bacteria, invasive fungal infections, severe viral infections, Ebola virus disease and paediatrics.

scientific article

[Communication with the relatives of a patient presumed brain dead]

scientific article published on 01 January 2011

[Peripheral circulation in critically ill patients: non-invasive methods for the assessment of the peripheral perfusion]

scientific article published on 01 January 2013

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