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List of works by Didier Bouscary

A phase Ib GOELAMS study of the mTOR inhibitor RAD001 in association with chemotherapy for AML patients in first relapse.

scientific article published on 16 January 2013

Activity of the caspase-3/CPP32 enzyme is increased in “early stage” myelodysplastic syndromes with excessive apoptosis, but caspase inhibition does not enhance colony formation in vitro

scientific article published on 01 July 2000

Analysis of megakaryocyte growth and development factor (thrombopoietin) effects on blast cell and megakaryocyte growth in myelodysplasia.

scientific article

Anorexia nervosa hyperactivity-induced ischemic colitis (ANHIC): a new cause of anaemia

scientific article published on 17 June 2016

Antileukemic HLA-restricted T-cell clones generated with naturally processed peptides eluted from acute myeloblastic leukemia blasts ⬇️

scientific article published on July 1, 1998

Antileukemic activity of the VPS34-IN1 inhibitor in acute myeloid leukemia

scientific article published on 22 October 2020

Architectural and functional heterogeneity of hematopoietic stem/progenitor cells in non-del(5q) myelodysplastic syndromes.

scientific article published on 16 November 2016

Autoimmune haemolytic anaemia revealing miliary tuberculosis

scientific article published on 01 May 2000

Autologous stem cell transplantation in patients who object to a blood transfusion: contribution of new pharmacological haematopoiesis support

scientific article published on 11 March 2013

Azacitidine for the treatment of relapsed and refractory AML in older patients

scientific article published on 24 November 2014

Bcl–2 protects from lethal hepatic apoptosis induced by an ant–Fas antibody in mice

scientific article published on 01 January 1996

Bortezomib Does Not Prevent the Occurrence of Kaposi's Sarcoma in Patients with Haematological Malignancies: Two Case Reports

scientific article published on 9 June 2017

Bortezomib, doxorubicin and dexamethasone association is an effective option for plasma cell leukemia induction therapy.

scientific article

Caspase activation is required for terminal erythroid differentiation

scientific article

Castleman's disease (giant lymph node hyperplasia): clinical, biological and developing polymorphism. Apropos of 4 cases

scientific article published in January 1990

Chromosomal abnormalities are major prognostic factors in elderly patients with multiple myeloma: the intergroupe francophone du myélome experience

scientific article published on 24 June 2013

Chronic myelomonocytic leukemia associated with generalized myasthenia gravis

scientific article published on 6 November 2013

Clinical and biological features of t(4;14) multiple myeloma: a prospective study

scientific article published on 24 January 2011

Clonal chromosomal abnormalities identified by interphase fluorescence in situ hybridization on collagen cultured hematopoietic stem cells

scientific article published on 01 May 2000

Co-activation of AMPK and mTORC1 Induces Cytotoxicity in Acute Myeloid Leukemia

scientific article published on 20 May 2015

Common 4q24 deletion in four cases of hematopoietic malignancy: early stem cell involvement?

scientific article published on 01 August 2005

Complex karyotype in mantle cell lymphoma is a strong prognostic factor for the time to treatment and overall survival, independent of the MCL international prognostic index

scientific article

Constitutive phosphoinositide 3-kinase activation in acute myeloid leukemia is not due to p110delta mutations

scientific article published on 01 February 2006

Constitutive phosphoinositide 3-kinase/Akt activation represents a favorable prognostic factor in de novo acute myelogenous leukemia patients.

scientific article published on 10 April 2007

Control of Pim2 kinase stability and expression in transformed human haematopoietic cells

scientific article

Critical role for PI 3-kinase in the control of erythropoietin-induced erythroid progenitor proliferation.

scientific article

Cytoplasmic proliferating cell nuclear antigen connects glycolysis and cell survival in acute myeloid leukemia

scientific article published on 19 October 2016

Disseminated Scopulariopsis brevicaulis infection in an allogeneic stem cell recipient

scientific article published on 29 November 2010

Dual inhibition of PI3K and mTORC1/2 signaling by NVP-BEZ235 as a new therapeutic strategy for acute myeloid leukemia.

scientific article published on 30 September 2010

Early matched sibling hematopoietic cell transplantation for adult AML in first remission using an age-adapted strategy: long-term results of a prospective GOELAMS study

scientific article published on 09 February 2012

Ectopic expression of murine TPO receptor (c-mpl) in mice is pathogenic and induces erythroblastic proliferation.

scientific article

Effect of spacing intravenous bisphosphonates in patients with multiple myeloma in plateau phase.

scientific article published on 26 April 2007

Effectiveness and tolerance of low to very low dose thalidomide in low-risk myelodysplastic syndromes.

scientific article published on 21 July 2008

Elevated thrombopoietin serum concentrations in myelodysplasias

scientific article published on 01 January 1998

Essential role for the p110 isoform in phosphoinositide 3-kinase activation and cell proliferation in acute myeloid leukemia

scientific article published on 19 April 2005

Expression of the Evi-1 gene in myelodysplastic syndromes

scientific article published on 01 January 1995

Expression of the transcription factor Evi-1 in human erythroleukemia cell lines and in leukemias

scientific article published in February 1997

FLT3 inhibitors: clinical potential in acute myeloid leukemia.

scientific article published on 03 February 2017

Fas/Apo-1(CD95) expression and apoptosis in patients with myelodysplastic syndromes

scientific article published on 01 June 1997

Flow cytometric quantification of all phases of the cell cycle and apoptosis in a two-color fluorescence plot.

scientific article

HHV-8 and multiple myeloma in France

scientific article published in The Lancet

Helical tomotherapy and systemic targeted therapies in solitary plasmacytoma: Pilot study

scientific article published on June 2013

Hemophagocytic histiocytosis (HH) in renal transplant recipients under ciclosporin therapy: report of the first two cases.

scientific article published on April 1995

Hemophagocytic syndrome associated with Bacteroides fragilis infection in a patient with acute monoblastic leukemia

scientific article published on 01 June 1996

High levels of CD34+CD38low/-CD123+ blasts are predictive of an adverse outcome in acute myeloid leukemia: a Groupe Ouest-Est des Leucemies Aigues et Maladies du Sang (GOELAMS) study.

scientific article published on 20 September 2011

High mTORC1 activity drives glycolysis addiction and sensitivity to G6PD inhibition in acute myeloid leukemia cells

scientific article published on 10 March 2017

In vitro proliferation and differentiation of erythroid progenitors from patients with myelodysplastic syndromes: evidence for Fas-dependent apoptosis.

scientific article published in March 2002

Ineffective erythropoiesis in myelodysplastic syndromes: correlation with Fas expression but not with lack of erythropoietin receptor signal transduction

scientific article published on 01 August 1999

Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia.

scientific article published on 06 September 2013

Insulin receptor A and IGF-1R in AML - Letter.

scientific article

Intensified-dose (4 gm/m2) cyclophosphamide and granulocyte colony-stimulating factor administration for hematopoietic stem cell mobilization in refractory rheumatoid arthritis

scientific article published on 01 November 1999

Isodicentric/pseudoisodicentric chromosome 21 amplification in four cases of acute myelocytic leukemia or myelodysplasia

scientific article published on 01 October 2002

IκB kinase overcomes PI3K/Akt and ERK/MAPK to control FOXO3a activity in acute myeloid leukemia

scientific article published on 29 July 2010

LKB1/AMPK/mTOR signaling pathway in hematological malignancies: from metabolism to cancer cell biology.

scientific article published on July 2011

Lack of evidence of an association between HHV-8 and multiple myeloma

article

Large granular lymphocyte leukemia associated with hepatitis C virus infection and B cell lymphoma: improvement after antiviral therapy

scientific article published on 26 December 2012

Leukemic cell xenograft in zebrafish embryo for investigating drug efficacy.

scientific article

Leukemic phase of follicular lymphomas: an atypical presentation.

scientific article published on 17 May 2011

Listeria monocytogenes meningitis following imatinib mesylate-induced monocytopenia in a patient with chronic myeloid leukemia.

scientific article published in December 2005

Long-term analysis of the IFM 99 trials for myeloma: cytogenetic abnormalities [t(4;14), del(17p), 1q gains] play a major role in defining long-term survival.

scientific article published on 30 April 2012

Long-term remission of an EBV-positive B cell lymphoproliferative disorder associated with rheumatoid arthritis under methotrexate with anti-CD20 monoclonal antibody (Rituximab) monotherapy.

scientific article published in October 2002

Long-term results of a randomized phase 3 trial comparing idarubicin and daunorubicin in younger patients with acute myeloid leukaemia

scientific article published on 09 October 2013

Maintenance therapy with alternating azacitidine and lenalidomide in elderly fit patients with poor prognosis acute myeloid leukemia: a phase II multicentre FILO trial.

scientific article published on 2 June 2017

Mammalian target of rapamycin (mTOR) inhibition activates phosphatidylinositol 3-kinase/Akt by up-regulating insulin-like growth factor-1 receptor signaling in acute myeloid leukemia: rationale for therapeutic inhibition of both pathways.

scientific article

Mitoxantrone-related acute myeloblastic leukaemia in a patient with metastatic hormone-refractory prostate cancer

scientific article published on 01 February 2007

Neutrophilic myositis sine dermatitis in a neutropenic patient with myelodysplastic syndrome

scientific article

Nucleophosmin status may influence the therapeutic decision in de novo acute myeloid leukemia with normal karyotype

scientific article published on 22 June 2006

PI-103, a dual inhibitor of Class IA phosphatidylinositide 3-kinase and mTOR, has antileukemic activity in AML.

scientific article published on 12 June 2008

PI3K and mTOR signaling pathways in cancer: new data on targeted therapies

scientific article

Paroxysmal nocturnal hemoglobinuria and pregnancy before the eculizumab era: the French experience

scientific article

Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia

scientific article

Place of modern imaging modalities for solitary plasmacytoma: toward improved primary staging and treatment monitoring.

scientific article published on 28 May 2011

Plasmocytomes cutanés associés au virus Epstein-Barr chez les transplantés d’organes

scientific article published on 01 December 2004

Polymyositis Associated with Ki-1 Lymphoma

Primary bone diffuse large B-cell lymphoma: a retrospective evaluation on 76 cases from French institutional and LYSA studies

scientific article published on 27 April 2016

Primary follicular lymphoma of the gastrointestinal tract: a study of 25 cases and a literature review.

scientific article

Proceedings of Réanimation 2017, the French Intensive Care Society International Congress

scientific article published on 10 January 2017

Prognostic impact of day 15 blast clearance in risk-adapted remission induction chemotherapy for younger patients with acute myeloid leukemia: long-term results of the multicenter prospective LAM-2001 trial by the GOELAMS study group

scientific article

Prognostic value of c-mpl expression in myelodysplastic syndromes

scientific article published on 01 May 1995

Protein synthesis is resistant to rapamycin and constitutes a promising therapeutic target in acute myeloid leukemia.

scientific article

Pseudouveitis: a clue to the diagnosis of primary central nervous system lymphoma in immunocompetent patients

scientific article published on 01 July 2004

Rational for targeting the hedgehog signalling pathway in acute myeloid leukemia with FLT3 mutation

scientific article published on October 2016

Remission of nonerosive polyarthritis associated with Sjögren's syndrome after autologous hematopoietic stem cell transplantation for lymphoma

scientific article published on 01 December 1997

Ribavirin therapy for cryoglobulinemia and thrombocytopenia associated with hepatitis C virus infection.

scientific article published in December 1997

Rituximab (anti-CD20 monoclonal antibody) for the treatment of patients with clonal lymphoproliferative disorders after orthotopic liver transplantation: a report of three cases

scientific article published on 01 March 2000

Role of autologous hematopoietic stem cell transplantation according to the NPM1/FLT3-ITD molecular status for cytogenetically normal AML patients: a GOELAMS study

scientific article published on 22 August 2012

Role of the PI3K/AKT and mTOR signaling pathways in acute myeloid leukemia.

scientific article

Salvage therapy of Autoimmune Thrombocytopenic Purpura revealing non-Hodgkin Lymphoma by the thrombopoietin receptor agonist romiplostim

Single cell analysis of phosphoinositide 3-kinase/Akt and ERK activation in acute myeloid leukemia by flow cytometry

scientific article published on 01 June 2006

Successful treatment of acquired factor VIII inhibitor with fludarabine and cyclophosphamide in chronic lymphoid leukemia

scientific article published on 01 August 1999

Successful treatment of l-asparaginase-induced severe acute hepatotoxicity using mitochondrial cofactors

scientific article published on 14 November 2013

Sustained leukemia-free state and molecular response to sorafenib in a patient with chronic myelomonocytic leukemia in transformation driven by homozygous FLT3-ITD malignant hematopoiesis.

scientific article

TET2 mutations in secondary acute myeloid leukemias: a French retrospective study ⬇️

scientific article published on April 20, 2011

Tandem versus single autologous peripheral blood stem cell transplantation as post-remission therapy in adult acute myeloid leukemia patients under 60 in first complete remission: results of the multicenter prospective phase III GOELAMS LAM-2001 tri

scientific article published on 27 May 2010

Targeting glutamine uptake in AML

scientific article published on 10 January 2014

Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition

scientific article

The FLT3 and Pim kinases inhibitor SGI-1776 preferentially target FLT3-ITD AML cells

scientific article published in February 2012

The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation

scientific article published on 28 July 2010

The cap-translation inhibitor 4EGI-1 induces apoptosis in multiple myeloma through Noxa induction.

scientific article

The dual mTORC1 and mTORC2 inhibitor AZD8055 has anti-tumor activity in acute myeloid leukemia.

scientific article published on 6 December 2011

The eukaryotic initiating factor 4E protein is overexpressed, but its level has no prognostic impact in acute myeloid leukaemia.

scientific article published on 14 October 2011

The role of helical tomotherapy in the treatment of bone plasmacytoma

scientific article published on 25 June 2011

Thrombocytemia and abnormal megakaryopoiesis associated with abnormality of chromosome 1p34 in myelodysplastic syndromes.

scientific article

Thrombopoietin is not responsible for the thrombocytosis observed in patients with acute myeloid leukemias and the 3q21q26 syndrome

scientific article published on 01 October 1995

Treatment of Adult T-Cell Leukemia-Lymphoma with Zidovudine and Interferon Alfa

Treatment of myelodysplastic syndromes with 5q deletion before the lenalidomide era; the GFM experience with EPO and thalidomide

scientific article

Treatment with lenalidomide does not appear to increase the risk of progression in lower risk myelodysplastic syndromes with 5q deletion. A comparative analysis by the Groupe Francophone des Myelodysplasies

scientific article published on 11 October 2011

Tuberculosis due to Mycobacterium bovis after alemtuzumab administration

scientific article published on 09 July 2003

Type I cryoglobulinemia in multiple myeloma, a rare entity: analysis of clinical and biological characteristics of seven cases and review of the literature.

scientific article published on 19 April 2012

When can real-time quantitative RT-PCR effectively define molecular relapse in acute promyelocytic leukemia patients? (Results of the French Belgian Swiss APL Group).

scientific article

[Acyclovir-resistance zona in a immunocompromised HIV seronegative patient]

scientific article published on 01 February 1998

[Bone marrow transplantation in the treatment of autoimmune diseases. ISAMAIR Group]

scientific article published on 01 September 1999

[Co-activation of AMPK and mTORC1: a therapeutic application of synthetic lethality in acute myeloid leukemia].

scientific article published on 19 October 2015

[Serum monoclonal immunoglobulins and HIV-I infection]

scientific article published on 01 June 1987

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