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List of works by Jerome Tamburini

A novel, dual pan-PIM/FLT3 inhibitor SEL24 exhibits broad therapeutic potential in acute myeloid leukemia.

scientific article published on 30 March 2018

A phase Ib GOELAMS study of the mTOR inhibitor RAD001 in association with chemotherapy for AML patients in first relapse.

scientific article published on 16 January 2013

AMPK Activation Promotes Tight Junction Assembly in Intestinal Epithelial Caco-2 Cells

scientific article published on 18 October 2019

Acute bacterial meningitis in a patient receiving ibuprofen.

scientific article

Adrenomedullin-CALCRL axis controls relapse-initiating drug tolerant acute myeloid leukemia cells

scientific article published on 18 January 2021

Antileukaemic effect of PI3K-mTOR inhibitors in acute myeloid leukaemia-gene expression profiles reveal CDC25B expression as determinate of pharmacological effect

scientific article published on 23 October 2013

Antileukemic Activity of 2-Deoxy-d-Glucose through Inhibition of N-Linked Glycosylation in Acute Myeloid Leukemia with FLT3-ITD or c-KIT Mutations

scientific article published on 23 July 2015

Aplastic anemia in the elderly: a nationwide survey on behalf of the French Reference Center for Aplastic Anemia

article

Autologous stem cell transplantation in patients who object to a blood transfusion: contribution of new pharmacological haematopoiesis support

scientific article published on 11 March 2013

Autologous111 Indium-oxinate-labelled platelet sequestration study in patients with immune thrombocytopenia treated by thrombopoietin receptor-agonists

scientific article published on 04 April 2019

Balancing risk versus benefit in the treatment of Waldenström's Macroglobulinemia patients with nucleoside analogue-based therapy

scientific article published on 01 March 2009

Bortezomib, doxorubicin and dexamethasone association is an effective option for plasma cell leukemia induction therapy.

scientific article

CDC25A governs proliferation and differentiation of FLT3-ITD acute myeloid leukemia.

scientific article published on 16 October 2015

Chronic myelomonocytic leukemia associated with generalized myasthenia gravis

scientific article published on 6 November 2013

Co-activation of AMPK and mTORC1 Induces Cytotoxicity in Acute Myeloid Leukemia

scientific article published on 20 May 2015

Co-activation of AMPK and mTORC1 as a new therapeutic option for acute myeloid leukemia.

scientific article published on 27 August 2015

Co-activation of AMPK and mTORC1: a therapeutic application of synthetic lethality in acute myeloid leukemia

scientific article published on 19 October 2015

Constitutive phosphoinositide 3-kinase activation in acute myeloid leukemia is not due to p110delta mutations

scientific article published on 01 February 2006

Constitutive phosphoinositide 3-kinase/Akt activation represents a favorable prognostic factor in de novo acute myelogenous leukemia patients.

scientific article published on 10 April 2007

Control of Pim2 kinase stability and expression in transformed human haematopoietic cells

scientific article

Core-binding factor acute myeloid leukemia in first relapse: a retrospective study from the French AML Intergroup

scientific article published on 08 July 2014

Cytokine pattern in Kaposi??s sarcoma associated with immune restoration disease in HIV and tuberculosis co-infected patients

article

Dual inhibition of PI3K and mTORC1/2 signaling by NVP-BEZ235 as a new therapeutic strategy for acute myeloid leukemia.

scientific article published on 30 September 2010

Effectiveness and tolerance of low to very low dose thalidomide in low-risk myelodysplastic syndromes.

scientific article published on 21 July 2008

Efficacy and long-term toxicity of the rituximab-fludarabine-cyclophosphamide combination therapy in Waldenstrom's macroglobulinemia

scientific article

Efficacy and safety of high-dose etoposide cytarabine as consolidation following rituximab methotrexate temozolomide induction in newly diagnosed primary central nervous system lymphoma in immunocompetent patients

scientific article published on 22 February 2018

Efficacy of tyrosine kinase inhibitors in Ph-like acute lymphoblastic leukemia harboring ABL-class rearrangements

scientific article published on 01 October 2019

Establishing assay-specific 97.5th percentile upper reference limit for serum D-2-hydroxyglutarate for the management of patients with acute myeloid leukemia

scientific article published on 01 March 2019

Evidence for IL-35 Expression in Diffuse Large B-Cell Lymphoma and Impact on the Patient's Prognosis

scientific article published on 28 June 2019

Extracellular ATP and CD39 activate cAMP-mediated mitochondrial stress response to promote cytarabine resistance in acute myeloid leukemia

scientific article published on 08 July 2020

FLT3 inhibitors: clinical potential in acute myeloid leukemia.

scientific article published on 03 February 2017

Feasibility of helical tomotherapy for debulking irradiation before stem cell transplantation in malignant lymphoma

scientific article published on 18 June 2010

Finely-tuned regulation of AMP-activated protein kinase (AMPK) is crucial for human adult erythropoiesis

scientific article published on 11 October 2018

Fludarabine plus cyclophosphamide in Waldenström's macroglobulinemia: results in 49 patients.

scientific article published in October 2005

Focal rituximab-induced edematous reaction at primary cutaneous follicle center lymphoma lesions: case report and literature review

scientific article published on 04 October 2011

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Helical tomotherapy and systemic targeted therapies in solitary plasmacytoma: Pilot study

scientific article published on June 2013

High levels of CD34+CD38low/-CD123+ blasts are predictive of an adverse outcome in acute myeloid leukemia: a Groupe Ouest-Est des Leucemies Aigues et Maladies du Sang (GOELAMS) study.

scientific article published on 20 September 2011

High mTORC1 activity drives glycolysis addiction and sensitivity to G6PD inhibition in acute myeloid leukemia cells

scientific article published on 10 March 2017

High-dose chemotherapy without transfusion for Philadelphia chromosome negative B-cell acute lymphoblastic leukemia in two Jehovah's Witnesses patients: a feasible option in the age of hematopoietic growth factors

scientific article published on 18 February 2019

High-dose thiotepa-based chemotherapy with autologous stem cell support in elderly patients with primary central nervous system lymphoma: a European retrospective study

scientific article published on 24 April 2017

Homoharringtonine (omacetaxine mepesuccinate) as an adjunct for FLT3-ITD acute myeloid leukemia.

scientific article published in October 2016

How should we diagnose and treat blastic plasmacytoid dendritic cell neoplasm patients?

scientific article published on 01 December 2019

Impact of genotype in relapsed and refractory acute myeloid leukaemia patients treated with clofarabine and cytarabine: a retrospective study

scientific article published on 18 June 2019

Indications and outcome of splenectomy in hematologic disease

scientific article published on 27 July 2017

Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia.

scientific article published on 06 September 2013

Insulin receptor A and IGF-1R in AML - Letter

scientific article

IκB kinase overcomes PI3K/Akt and ERK/MAPK to control FOXO3a activity in acute myeloid leukemia

scientific article published on 29 July 2010

Knockdown of Human AMPK Using the CRISPR/Cas9 Genome-Editing System.

scientific article published in January 2018

LAMP2 expression dictates azacytidine response and prognosis in MDS/AML

scientific article published on 03 January 2019

LKB1/AMPK/mTOR signaling pathway in hematological malignancies: from metabolism to cancer cell biology.

scientific article published on July 2011

Leukemic cell xenograft in zebrafish embryo for investigating drug efficacy.

scientific article

Leukemic phase of follicular lymphomas: an atypical presentation.

scientific article published on 17 May 2011

Listeria monocytogenes meningitis following imatinib mesylate-induced monocytopenia in a patient with chronic myeloid leukemia.

scientific article published in December 2005

Lung Abnormalities after Dasatinib Treatment for Chronic Myeloid Leukemia

scientific article published on 28 June 2007

MB4-2 breakpoint in MMSET combined with del(17p) defines a subset of t(4;14) multiple myeloma with very poor prognosis.

scientific article published on 23 July 2015

Mammalian target of rapamycin (mTOR) inhibition activates phosphatidylinositol 3-kinase/Akt by up-regulating insulin-like growth factor-1 receptor signaling in acute myeloid leukemia: rationale for therapeutic inhibition of both pathways.

scientific article

Management and outcome of primary CNS lymphoma in the modern era: An LOC network study

scientific article published on 06 January 2020

Mutations in G protein β subunits promote transformation and kinase inhibitor resistance

scientific article

Nucleophosmin status may influence the therapeutic decision in de novo acute myeloid leukemia with normal karyotype

scientific article published on 22 June 2006

Our experience of solitary plasmacytoma of the bone: improved PFS with a short-course treatment by IMiDs or proteasome inhibitors combined with intensity-modulated radiotherapy

scientific article published on 31 October 2017

PET2 -driven de-escalation therapy in 64 high-risk Hodgkin Lymphoma patients treated with escalated BEACOPP

scientific article published on 09 January 2015

PI-103, a dual inhibitor of Class IA phosphatidylinositide 3-kinase and mTOR, has antileukemic activity in AML.

scientific article published on 12 June 2008

PI3K and mTOR signaling pathways in cancer: new data on targeted therapies

scientific article

Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia

scientific article

Pim kinases phosphorylate Chk1 and regulate its functions in acute myeloid leukemia ⬇️

scientific article published on June 10, 2013

Predicting effects of kinase inhibitor in therapy for myeloid malignancies - the challenges in capturing disease heterogeneity

scientific article

Primary bone diffuse large B-cell lymphoma: a retrospective evaluation on 76 cases from French institutional and LYSA studies

scientific article published on 27 April 2016

Proceedings of Réanimation 2017, the French Intensive Care Society International Congress

scientific article published on 10 January 2017

Profound anaemia and acute blindness in a Jehovah's Witness.

scientific article published in September 2013

Prognostic value of early 18F-FDG PET scanning evaluation in immunocompetent primary CNS lymphoma patients

scientific article

Prognostic value of the International Scoring System and response in patients with advanced Waldenstrom macroglobulinemia

scientific article

Proteasome inhibitors induce FLT3-ITD degradation through autophagy in AML cells.

scientific article published on 18 August 2015

Protein synthesis is resistant to rapamycin and constitutes a promising therapeutic target in acute myeloid leukemia.

scientific article

Proton beam therapy for the management of mediastinal Hodgkin lymphoma in a young female patient

scientific article published on 30 March 2018

RSK2 is a new Pim2 target with pro-survival functions in FLT3-ITD-positive acute myeloid leukemia.

scientific article

Rationale for Targeting Deregulated Metabolic Pathways as a Therapeutic Strategy in Acute Myeloid Leukemia

scientific article published on 22 May 2019

Rituximab therapy for hairy cell leukemia: a retrospective study of 41 cases

scientific article published on 07 September 2014

Role of the PI3K/AKT and mTOR signaling pathways in acute myeloid leukemia.

scientific article

S100 proteins in AML: differentiation and beyond

scientific article published in April 2017

Salvage therapy of Autoimmune Thrombocytopenic Purpura revealing non-Hodgkin Lymphoma by the thrombopoietin receptor agonist romiplostim

Single cell analysis of phosphoinositide 3-kinase/Akt and ERK activation in acute myeloid leukemia by flow cytometry

scientific article published on 01 June 2006

Sinusoidal obstruction syndrome: a warning about autologous stem cell transplantation preceded by regimens containing oxaliplatin

scientific article published on 20 January 2020

Successful treatment of l-asparaginase-induced severe acute hepatotoxicity using mitochondrial cofactors

scientific article published on 14 November 2013

Sustained leukemia-free state and molecular response to sorafenib in a patient with chronic myelomonocytic leukemia in transformation driven by homozygous FLT3-ITD malignant hematopoiesis

scientific article

T-cell large granular lymphocyte leukemia transfomation into aggressive T-cell lymphoma: a report of two cases with molecular characterization

scientific article published on 20 December 2018

Tandem haematopoietic stem cell transplantation for High Risk relapsed/refractory Hodgkin Lymphoma: a LYSA study.

scientific article published on 2 April 2018

Targeting CHK1 inhibits cell proliferation in FLT3-ITD positive acute myeloid leukemia.

scientific article published on 16 September 2014

Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition

scientific article

The FLT3 and Pim kinases inhibitor SGI-1776 preferentially target FLT3-ITD AML cells

scientific article published in February 2012

The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation

scientific article published on 28 July 2010

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

scientific article published on April 2016

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

scientific article published on 11 July 2016

The cap-translation inhibitor 4EGI-1 induces apoptosis in multiple myeloma through Noxa induction.

scientific article

The dual mTORC1 and mTORC2 inhibitor AZD8055 has anti-tumor activity in acute myeloid leukemia.

scientific article published on 6 December 2011

The eukaryotic initiating factor 4E protein is overexpressed, but its level has no prognostic impact in acute myeloid leukaemia.

scientific article published on 14 October 2011

Type I cryoglobulinemia in multiple myeloma, a rare entity: analysis of clinical and biological characteristics of seven cases and review of the literature.

scientific article published on 19 April 2012

Urgent Chemotherapy in Sepsis-Like Shock Related to Hematologic Malignancies.

scientific article published on 25 January 2018

Vitamin D Receptor Controls Cell Stemness in Acute Myeloid Leukemia and in Normal Bone Marrow

scientific article published on 01 January 2020

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