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List of works by Gianluca Sala

A phosphoinositide 3-kinase/phospholipase Cgamma1 pathway regulates fibroblast growth factor-induced capillary tube formation

scientific article

ABCC3 is a novel target for the treatment of pancreatic cancer

scientific article published on 24 April 2019

An ErbB-3 antibody, MP-RM-1, inhibits tumor growth by blocking ligand-dependent and independent activation of ErbB-3/Akt signaling.

scientific article

Antibody-Drug Conjugates: The New Frontier of Chemotherapy

scientific article published on 31 July 2020

BAG3 promotes pancreatic ductal adenocarcinoma growth by activating stromal macrophages.

scientific article

CAF-Derived IL6 and GM-CSF Cooperate to Induce M2-like TAMs-Letter

scientific article published on 01 January 2019

Combined effect of anti-BAG3 and anti-PD-1 treatment on macrophage infiltrate, CD8(+) T cell number and tumour growth in pancreatic cancer.

scientific article published on 11 August 2017

Concerted BAG3 and SIRPα blockade impairs pancreatic tumor growth

scientific article published on 03 March 2022

Development of an anti-BAG3 humanized antibody for treatment of pancreatic cancer

scientific article published on 17 May 2019

Dual PDK1/Aurora Kinase A Inhibitors Reduce Pancreatic Cancer Cell Proliferation and Colony Formation

scientific article published on 31 October 2019

Dual targeting of ErbB-2/ErbB-3 results in enhanced antitumor activity in preclinical models of pancreatic cancer

scientific article published on 18 August 2014

EV20, a Novel Anti-ErbB-3 Humanized Antibody, Promotes ErbB-3 Down-Regulation and Inhibits Tumor Growth In Vivo.

scientific article published on December 2013

EV20-Sap, a novel anti-HER-3 antibody-drug conjugate, displays promising antitumor activity in melanoma.

scientific article published on 8 September 2017

EV20-mediated delivery of cytotoxic auristatin MMAF exhibits potent therapeutic efficacy in cutaneous melanoma.

scientific article published on 14 March 2018

Engineered Human Nanoferritin Bearing the Drug Genz-644282 for Cancer Therapy

scientific article published on 20 October 2020

Expression of RALT, a feedback inhibitor of ErbB receptors, is subjected to an integrated transcriptional and post-translational control

scientific article (publication date: 19 September 2002)

Feedback inhibition by RALT controls signal output by the ErbB network

scientific article (publication date: 3 July 2003)

Functional and prognostic significance of the genomic amplification of frizzled 6 (FZD6) in breast cancer

scientific article

GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in mice, and its inhibition increases effects of gemcitabine

scientific article published on 30 July 2018

HER-3: hub for escape mechanisms.

scientific article published on 18 November 2015

HER3 targeting with an antibody-drug conjugate bypasses resistance to anti-HER2 therapies

scientific article published on 24 April 2020

Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines.

scientific article published on February 2015

Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans

scientific article published on 28 March 2022

PLC-gamma-1 phosphorylation status is prognostic of metastatic risk in patients with early-stage Luminal-A and -B breast cancer subtypes

scientific article published on 30 July 2019

Pharmacological inhibition of ABCC3 slows tumour progression in animal models of pancreatic cancer

scientific article published on 05 August 2019

Phospholipase Cgamma1 is required for metastasis development and progression

scientific article

Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer

scientific article published on 14 May 2019

Repurposing a psychoactive drug for children with cancer: p27Kip1-dependent inhibition of metastatic neuroblastomas by Prozac

scientific article published on 02 January 2020

Role of BAG3 in cancer progression: A therapeutic opportunity.

scientific article published on 29 August 2017

Secreted Gal-3BP is a novel promising target for non-internalizing Antibody-Drug Conjugates

scientific article published on 13 December 2018

Targeting Vesicular LGALS3BP by an Antibody-Drug Conjugate as Novel Therapeutic Strategy for Neuroblastoma

scientific article published on 15 October 2020

The E27 beta2-adrenergic receptor polymorphism reduces the risk of myocardial infarction in dyslipidemic young males

scientific article published on 01 February 2001

The G-protein-coupled receptor kinase GRK4 mediates homologous desensitization of metabotropic glutamate receptor 1

scientific journal article

The Role of Phosphoinositide 3-Kinase C2α in Insulin Signaling

scientific article published in Journal of Biological Chemistry

The role of phospholipase Cγ1 in breast cancer and its clinical significance

scientific article published on 22 August 2017

Therapeutic Efficacy of the Novel Stimuli-Sensitive Nano-Ferritins Containing Doxorubicin in a Head and Neck Cancer Model.

scientific article published on 18 July 2017

miR-205-5p-mediated downregulation of ErbB/HER receptors in breast cancer stem cells results in targeted therapy resistance.

scientific article

miR-574-5p as RNA decoy for CUGBP1 stimulates human lung tumor growth by mPGES-1 induction

scientific article published on 28 March 2019

p63 role in breast cancer

scientific article published on 26 October 2016

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