List of works - Erik D. Roberson

100 years and counting: prospects for defeating Alzheimer's disease

scientific article published on November 2006

14-3-3θ Does Not Protect against Behavioral or Pathological Deficits in Alzheimer's Disease Mouse Models

scientific article published in 2022

18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery

scientific article published in February 2018

A REDCap-based model for electronic consent (eConsent): Moving toward a more personalized consent

scientific article published on 03 April 2020

A role for superoxide in protein kinase C activation and induction of long-term potentiation.

scientific article

ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects

scientific article published on 10 February 2014

Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease

scientific article published in September 2007

Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy

scientific article published on 07 January 2021

Abnormal social behaviors in mice lacking Fgf17.

scientific article published in October 2007

Alzheimer's disease risk gene BIN1 induces Tau-dependent network hyperexcitability

scientific article published on 13 July 2020

Amyloid-β signals through tau to drive ectopic neuronal cell cycle re-entry in Alzheimer's disease.

scientific article

Amyloid-β/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease.

scientific article

Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer's disease

scientific article published on September 2006

Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint

scientific article published on 01 January 2020

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Beyond diagnosis: what biomarkers are teaching us about the "bio"logy of Alzheimer disease

scientific article published in March 2010

Brain volumetric deficits in MAPT mutation carriers: a multisite study

scientific article published on 28 November 2020

Challenges and opportunities for characterizing cognitive aging across species

scientific article

Clinical and volumetric changes with increasing functional impairment in familial frontotemporal lobar degeneration

scientific article published on 06 January 2020

Clinical, imaging, pathological, and biochemical characterization of a novel presenilin 1 mutation (N135Y) causing Alzheimer's disease

scientific article published on 3 October 2016

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

scientific article

Comparison of Pittsburgh compound B and florbetapir in cross-sectional and longitudinal studies

article

Contemporary approaches to Alzheimer's disease and frontotemporal dementia.

scientific article published on January 2011

DNA methylation slows effects of C9orf72 mutations: An epigenetic brake on genetic inheritance

scientific article published on 20 March 2015

Davunetide in patients with progressive supranuclear palsy: a randomised, double-blind, placebo-controlled phase 2/3 trial

scientific article

Dissociation of frontotemporal dementia-related deficits and neuroinflammation in progranulin haploinsufficient mice

scientific article published on March 2013

Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD

scientific article

Effects of Exercise on Progranulin Levels and Gliosis in Progranulin-Insufficient Mice

scientific article

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

scientific article

Enkephalin elevations contribute to neuronal and behavioral impairments in a transgenic mouse model of Alzheimer's disease

scientific article

Frontotemporal degeneration, the next therapeutic frontier: molecules and animal models for frontotemporal degeneration drug development

scientific article published on 05 October 2012

Frontotemporal dementia

scientific article published on 01 November 2006

Genetic influences on cognition in progressive supranuclear palsy.

scientific article published on 27 October 2017

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Genetic screening of a large series of North American sporadic and familial frontotemporal dementia cases

scientific article published on 01 January 2020

Geriatric epilepsy: research and clinical directions for the future

scientific article published on 19 May 2011

Holocranohistochemistry enables the visualization of α-synuclein expression in the murine olfactory system and discovery of its systemic anti-microbial effects

scientific article

Identification of an insulin-like factor in astrocyte conditioned medium

scientific article published on 01 September 1988

Impaired β-glucocerebrosidase activity and processing in frontotemporal dementia due to progranulin mutations

scientific article published on 23 December 2019

Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degeneration

scientific article published on 06 January 2020

Loss of Hsp70 exacerbates pathogenesis but not levels of fibrillar aggregates in a mouse model of Huntington's disease

scientific article published on July 2009

Memory-forming chemical reactions.

scientific article

MicroRNA-124 modulates social behavior in frontotemporal dementia

scientific article (publication date: 4 December 2014)

Mouse models of Alzheimer's disease ⬇️

scientific article published on November 28, 2011

Mouse models of frontotemporal dementia

scientific article

Noradrenergic dysfunction in Alzheimer's disease.

scientific article published on 17 June 2015

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

scientific article

Partial Tmem106b reduction does not correct abnormalities due to progranulin haploinsufficiency.

scientific article

Polyneuropathy following gastric bypass surgery

scientific article

Progranulin Gene Therapy Improves Lysosomal Dysfunction and Microglial Pathology Associated with Frontotemporal Dementia and Neuronal Ceroid Lipofuscinosis.

scientific article published on 29 January 2018

Quantifying biomarkers of cognitive dysfunction and neuronal network hyperexcitability in mouse models of Alzheimer's disease: depletion of calcium-dependent proteins and inhibitory hippocampal remodeling

scientific article

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article

Rarity of the Alzheimer disease-protective APP A673T variant in the United States

scientific article

Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

scientific article (publication date: 4 May 2007)

Restoring neuronal progranulin reverses deficits in a mouse model of frontotemporal dementia

scientific article published on 29 March 2017

Revised Self-Monitoring Scale: A potential endpoint for frontotemporal dementia clinical trials

scientific article published on 05 May 2020

Seizure resistance without parkinsonism in aged mice after tau reduction

scientific article

Step-by-Step In Situ Hybridization Method for Localizing Gene Expression Changes in the Brain ⬇️

scientific article published on January 1, 2011

TAU ablation in excitatory neurons and postnatal TAU knockdown reduce epilepsy, SUDEP, and autism behaviors in a Dravet syndrome model

scientific article published on 27 April 2022

Tau-dependent Kv4.2 depletion and dendritic hyperexcitability in a mouse model of Alzheimer's disease

scientific article

Tau-mediated NMDA receptor impairment underlies dysfunction of a selectively vulnerable network in a mouse model of frontotemporal dementia

scientific article

The Alzheimer's disease risk factor CD2AP maintains blood-brain barrier integrity

scientific article

The dendritic hypothesis for Alzheimer's disease pathophysiology

scientific article

Transient activation of cyclic AMP-dependent protein kinase during hippocampal long-term potentiation.

scientific article published in November 1996

Usp14 deficiency increases tau phosphorylation without altering tau degradation or causing tau-dependent deficits

scientific article

Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium

scientific article published on 01 January 2020

Vascular amyloidosis impairs the gliovascular unit in a mouse model of Alzheimer's disease

scientific article

Vascular amyloidosis impairs the gliovascular unit in a mouse model of Alzheimer’s disease

β-amyloid redirects norepinephrine signaling to activate the pathogenic GSK3β/tau cascade

scientific article published on 01 January 2020

List of works by Erik D. Roberson

100 years and counting: prospects for defeating Alzheimer's disease

14-3-3θ Does Not Protect against Behavioral or Pathological Deficits in Alzheimer's Disease Mouse Models

18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery

A REDCap-based model for electronic consent (eConsent): Moving toward a more personalized consent

A role for superoxide in protein kinase C activation and induction of long-term potentiation.

ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects

Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease

Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy

Abnormal social behaviors in mice lacking Fgf17.

Alzheimer's disease risk gene BIN1 induces Tau-dependent network hyperexcitability

Amyloid-β signals through tau to drive ectopic neuronal cell cycle re-entry in Alzheimer's disease.

Amyloid-β/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease.

Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer's disease

Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Beyond diagnosis: what biomarkers are teaching us about the "bio"logy of Alzheimer disease

Brain volumetric deficits in MAPT mutation carriers: a multisite study

Challenges and opportunities for characterizing cognitive aging across species

Clinical and volumetric changes with increasing functional impairment in familial frontotemporal lobar degeneration

Clinical, imaging, pathological, and biochemical characterization of a novel presenilin 1 mutation (N135Y) causing Alzheimer's disease

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

Comparison of Pittsburgh compound B and florbetapir in cross-sectional and longitudinal studies

Contemporary approaches to Alzheimer's disease and frontotemporal dementia.

DNA methylation slows effects of C9orf72 mutations: An epigenetic brake on genetic inheritance

Davunetide in patients with progressive supranuclear palsy: a randomised, double-blind, placebo-controlled phase 2/3 trial

Dissociation of frontotemporal dementia-related deficits and neuroinflammation in progranulin haploinsufficient mice

Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD

Effects of Exercise on Progranulin Levels and Gliosis in Progranulin-Insufficient Mice

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

Enkephalin elevations contribute to neuronal and behavioral impairments in a transgenic mouse model of Alzheimer's disease

Frontotemporal degeneration, the next therapeutic frontier: molecules and animal models for frontotemporal degeneration drug development

Frontotemporal dementia

Genetic influences on cognition in progressive supranuclear palsy.

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Genetic screening of a large series of North American sporadic and familial frontotemporal dementia cases

Geriatric epilepsy: research and clinical directions for the future

Holocranohistochemistry enables the visualization of α-synuclein expression in the murine olfactory system and discovery of its systemic anti-microbial effects

Identification of an insulin-like factor in astrocyte conditioned medium

Impaired β-glucocerebrosidase activity and processing in frontotemporal dementia due to progranulin mutations

Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degeneration

Loss of Hsp70 exacerbates pathogenesis but not levels of fibrillar aggregates in a mouse model of Huntington's disease

Memory-forming chemical reactions.

MicroRNA-124 modulates social behavior in frontotemporal dementia

Mouse models of Alzheimer's disease ⬇️

Mouse models of frontotemporal dementia

Noradrenergic dysfunction in Alzheimer's disease.

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

Partial Tmem106b reduction does not correct abnormalities due to progranulin haploinsufficiency.

Polyneuropathy following gastric bypass surgery

Progranulin Gene Therapy Improves Lysosomal Dysfunction and Microglial Pathology Associated with Frontotemporal Dementia and Neuronal Ceroid Lipofuscinosis.

Quantifying biomarkers of cognitive dysfunction and neuronal network hyperexcitability in mouse models of Alzheimer's disease: depletion of calcium-dependent proteins and inhibitory hippocampal remodeling

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Rarity of the Alzheimer disease-protective APP A673T variant in the United States

Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

Restoring neuronal progranulin reverses deficits in a mouse model of frontotemporal dementia

Revised Self-Monitoring Scale: A potential endpoint for frontotemporal dementia clinical trials

Seizure resistance without parkinsonism in aged mice after tau reduction

Step-by-Step In Situ Hybridization Method for Localizing Gene Expression Changes in the Brain ⬇️

TAU ablation in excitatory neurons and postnatal TAU knockdown reduce epilepsy, SUDEP, and autism behaviors in a Dravet syndrome model

Tau-dependent Kv4.2 depletion and dendritic hyperexcitability in a mouse model of Alzheimer's disease

Tau-mediated NMDA receptor impairment underlies dysfunction of a selectively vulnerable network in a mouse model of frontotemporal dementia

The Alzheimer's disease risk factor CD2AP maintains blood-brain barrier integrity

The dendritic hypothesis for Alzheimer's disease pathophysiology

Transient activation of cyclic AMP-dependent protein kinase during hippocampal long-term potentiation.

Usp14 deficiency increases tau phosphorylation without altering tau degradation or causing tau-dependent deficits

Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium

Vascular amyloidosis impairs the gliovascular unit in a mouse model of Alzheimer's disease

Vascular amyloidosis impairs the gliovascular unit in a mouse model of Alzheimer’s disease

β-amyloid redirects norepinephrine signaling to activate the pathogenic GSK3β/tau cascade