List of works - Pierre-Eric Juif

A pharmacokinetic drug-drug interaction study between selexipag and midazolam, a CYP3A4 substrate, in healthy male subjects

scientific article published on 21 June 2017

Absolute Bioavailability of Ponesimod, a Selective S1P1 Receptor Modulator, in Healthy Male Subjects

scientific article published on 16 February 2016

Accelerated development of the dual orexin receptor antagonist ACT-541468: Integration of a microtracer in the first-in-human study

scientific article published on 15 February 2018

Biocomparison of Three Formulations of the S1P1 Receptor Modulator Ponesimod in Healthy Subjects.

scientific article published on June 2015

Cardiodynamic Interactions between Two S1P1 Receptor Modulators in an Experimental Clinical Setting: Different Pharmacokinetic Properties as an Opportunity to Mitigate First-Dose Heart Rate Effects

scientific article published on 01 July 2019

Characterization of the fast GABAergic inhibitory action of etifoxine during spinal nociceptive processing in male rats

scientific article published on 26 December 2014

Clinical Pharmacology of the Reversible and Potent P2Y12 Receptor Antagonist ACT-246475 After Single Subcutaneous Administration in Healthy Male Subjects

scientific article published on 08 August 2018

Clinical pharmacology, efficacy, and safety aspects of sphingosine-1-phosphate receptor modulators.

scientific article published on June 2016

Corticosterone analgesia is mediated by the spinal production of neuroactive metabolites that enhance GABAergic inhibitory transmission on dorsal horn rat neurons

scientific article published on 26 November 2014

Effects of multiple-dose ponesimod, a selective S1P1 receptor modulator, on lymphocyte subsets in healthy humans

scientific article published on 28 December 2016

Etifoxine analgesia in experimental monoarthritis: a combined action that protects spinal inhibition and limits central inflammatory processes.

scientific article published on 14 November 2013

Influence of Rifampin-Mediated Organic Anion-Transporting Polypeptide 1B1/1B3 Inhibition on the Pharmacokinetics of Clazosentan

scientific article published on 06 May 2019

Long-lasting spinal oxytocin analgesia is ensured by the stimulation of allopregnanolone synthesis which potentiates GABA(A) receptor-mediated synaptic inhibition.

scientific article

Metabolite profiling in early clinical drug development: current status and future prospects

scientific article

Mitigation of Initial Cardiodynamic Effects of the S1P1 Receptor Modulator Ponesimod Using a Novel Up-Titration Regimen.

scientific article published on 25 August 2016

Modelling pharmacokinetics and pharmacodynamics of the selective S1P1 receptor modulator cenerimod in healthy subjects and systemic lupus erythematosus patients

scientific article published on 14 January 2020

Neurohormonal effects of oxytocin and vasopressin receptor agonists on spinal pain processing in male rats.

scientific article published on 7 May 2013

Pain behavior and spinal cell activation due to carrageenan-induced inflammation in two inbred rat strains with differential hypothalamic-pituitary-adrenal axis reactivity.

scientific article published on 13 November 2011

Peripheral and central alterations affecting spinal nociceptive processing and pain at adulthood in rats exposed to neonatal maternal deprivation.

scientific article published on 10 June 2016

Pharmacokinetics, Pharmacodynamics, Tolerability, and Food Effect of Cenerimod, a Selective S1P₁ Receptor Modulator in Healthy Subjects.

scientific article published on 6 December 2017

Pharmacological rescue of nociceptive hypersensitivity and oxytocin analgesia impairment in a rat model of neonatal maternal separation

scientific article published on 01 December 2018

List of works by Pierre-Eric Juif