List of works - Hayley J. Newton

A Farnesylated Coxiella burnetii Effector Forms a Multimeric Complex at the Mitochondrial Outer Membrane during Infection

scientific article published on 27 February 2017

A bacterial ecto-triphosphate diphosphohydrolase similar to human CD39 is essential for intracellular multiplication of Legionella pneumophila

scientific article published on 26 March 2007

A screen of Coxiella burnetii mutants reveals important roles for Dot/Icm effectors and host autophagy in vacuole biogenesis

scientific article

Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires' disease

scientific article

Biogenesis of the Spacious Coxiella-Containing Vacuole Depends on Host Transcription Factors TFEB and TFE3

scientific article published on 20 February 2020

Characterisation of putative lactate synthetic pathways of Coxiella burnetii

scientific article published in 2021

Contribution of long polar fimbriae to the virulence of rabbit-specific enteropathogenic Escherichia coli

scientific article published on March 2004

Coxiella burnetii Secretion Systems ⬇️

scientific article published on January 1, 2012

Coxiella burnetii utilizes both glutamate and glucose during infection with glucose uptake mediated by multiple transporters

scientific article published on 01 October 2019

Disruption of Iron Homeostasis and Mitochondrial Metabolism Are Promising Targets to Inhibit Candida auris

scientific article published on 12 April 2022

Dot/Icm Effector Translocation by Legionella longbeachae Creates a Replicative Vacuole Similar to That of Legionella pneumophila despite Translocation of Distinct Effector Repertoires

scientific article

Dot/Icm-translocated proteins important for biogenesis of the Coxiella burnetii-containing vacuole identified by screening of an effector mutant sub-library

scientific article published on 16 January 2018

Effector Protein Cig2 Decreases Host Tolerance of Infection by Directing Constitutive Fusion of Autophagosomes with the Coxiella-Containing Vacuole.

scientific article published on 19 July 2016

Effector protein translocation by the Coxiella burnetii Dot/Icm type IV secretion system requires endocytic maturation of the pathogen-occupied vacuole

scientific article

EirA is a novel protein essential for intracellular replication of Coxiella burnetii

scientific article published on 23 March 2020

Enzymatic properties of an ecto-nucleoside triphosphate diphosphohydrolase from Legionella pneumophila: substrate specificity and requirement for virulence

scientific article published on 12 March 2008

Erratum for Kohler et al., Effector Protein Cig2 Decreases Host Tolerance of Infection by Directing Constitutive Fusion of Autophagosomes with the Coxiella-Containing Vacuole

scientific article published on 06 September 2016

Identification of Legionella pneumophila-specific genes by genomic subtractive hybridization with Legionella micdadei and identification of lpnE, a gene required for efficient host cell entry

scientific article

Inhibition of inflammasome activation by Coxiella burnetii type IV secretion system effector IcaA.

scientific article

Interaction between autophagic vesicles and the Coxiella-containing vacuole requires CLTC (clathrin heavy chain)

scientific article published on 29 July 2018

Legionella pneumophila strain 130b possesses a unique combination of type IV secretion systems and novel Dot/Icm secretion system effector proteins

scientific article

Loss of O-Linked Protein Glycosylation in Burkholderia cenocepacia Impairs Biofilm Formation and Siderophore Activity and Alters Transcriptional Regulators

scientific article published on 13 November 2019

Lysosomal degradation products induce Coxiella burnetii virulence

scientific article published on 09 March 2020

Molecular Detection of Legionella: Moving on From mip.

scientific article

Molecular pathogenesis of infections caused by Legionella pneumophila

scientific article

Multiple ecto-nucleoside triphosphate diphosphohydrolases facilitate intracellular replication of Legionella pneumophila

scientific article

Murine Alveolar Macrophages Are Highly Susceptible to Replication of Coxiella burnetii Phase II In Vitro

scientific article published on 13 June 2016

Near-unity nuclear polarization with an open-source 129Xe hyperpolarizer for NMR and MRI.

scientific article

Post-modern pathogens: surprising activities of translocated effectors from E. coli and Legionella

scientific article

Proteomic identification of Coxiella burnetii effector proteins targeted to the host cell mitochondria during infection

scientific article published on 11 November 2020

SdrA, an NADP(H)-regenerating enzyme, is crucial for Coxiella burnetii to resist oxidative stress and replicate intracellularly

scientific article published on 11 January 2020

Sel1 repeat protein LpnE is a Legionella pneumophila virulence determinant that influences vacuolar trafficking

scientific article

Significant role for ladC in initiation of Legionella pneumophila infection.

scientific article published on 21 April 2008

SopF, a phosphoinositide binding effector, promotes the stability of the nascent Salmonella-containing vacuole

scientific article published on 24 July 2019

Taming the Triskelion: Bacterial Manipulation of Clathrin

scientific article published on 27 February 2019

The Coxiella burnetii Dot/Icm System Creates a Comfortable Home through Lysosomal Renovation ⬇️

scientific article published on October 18, 2011

The Coxiella burnetii Dot/Icm System Delivers a Unique Repertoire of Type IV Effectors into Host Cells and Is Required for Intracellular Replication ⬇️

scientific article published on May 26, 2011

The Dot/Icm effector SdhA is necessary for virulence of Legionella pneumophila in Galleria mellonella and A/J mice

scientific article

The Legionella pneumophila F-box protein Lpp2082 (AnkB) modulates ubiquitination of the host protein parvin B and promotes intracellular replication.

scientific article published on 25 March 2010

The multifunctional enzyme S-adenosylhomocysteine/methylthioadenosine nucleosidase is a key metabolic enzyme in the virulence of Salmonella enterica var Typhimurium

scientific article published on 01 November 2019

The role of Rab GTPases in the transport of vacuoles containingLegionella pneumophilaandCoxiella burnetii ⬇️

scientific article published on December 1, 2012

The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-kappaB p65.

scientific article

Two novel point mutations in clinical Staphylococcus aureus reduce linezolid susceptibility and switch on the stringent response to promote persistent infection

scientific article

XeNA: an automated 'open-source' (129)Xe hyperpolarizer for clinical use

scientific article

List of works by Hayley J. Newton

A Farnesylated Coxiella burnetii Effector Forms a Multimeric Complex at the Mitochondrial Outer Membrane during Infection

A bacterial ecto-triphosphate diphosphohydrolase similar to human CD39 is essential for intracellular multiplication of Legionella pneumophila

A screen of Coxiella burnetii mutants reveals important roles for Dot/Icm effectors and host autophagy in vacuole biogenesis

Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires' disease

Biogenesis of the Spacious Coxiella-Containing Vacuole Depends on Host Transcription Factors TFEB and TFE3

Characterisation of putative lactate synthetic pathways of Coxiella burnetii

Contribution of long polar fimbriae to the virulence of rabbit-specific enteropathogenic Escherichia coli

Coxiella burnetii Secretion Systems ⬇️

Coxiella burnetii utilizes both glutamate and glucose during infection with glucose uptake mediated by multiple transporters

Disruption of Iron Homeostasis and Mitochondrial Metabolism Are Promising Targets to Inhibit Candida auris

Dot/Icm Effector Translocation by Legionella longbeachae Creates a Replicative Vacuole Similar to That of Legionella pneumophila despite Translocation of Distinct Effector Repertoires

Dot/Icm-translocated proteins important for biogenesis of the Coxiella burnetii-containing vacuole identified by screening of an effector mutant sub-library

Effector Protein Cig2 Decreases Host Tolerance of Infection by Directing Constitutive Fusion of Autophagosomes with the Coxiella-Containing Vacuole.

Effector protein translocation by the Coxiella burnetii Dot/Icm type IV secretion system requires endocytic maturation of the pathogen-occupied vacuole

EirA is a novel protein essential for intracellular replication of Coxiella burnetii

Enzymatic properties of an ecto-nucleoside triphosphate diphosphohydrolase from Legionella pneumophila: substrate specificity and requirement for virulence

Erratum for Kohler et al., Effector Protein Cig2 Decreases Host Tolerance of Infection by Directing Constitutive Fusion of Autophagosomes with the Coxiella-Containing Vacuole

Identification of Legionella pneumophila-specific genes by genomic subtractive hybridization with Legionella micdadei and identification of lpnE, a gene required for efficient host cell entry

Inhibition of inflammasome activation by Coxiella burnetii type IV secretion system effector IcaA.

Interaction between autophagic vesicles and the Coxiella-containing vacuole requires CLTC (clathrin heavy chain)

Legionella pneumophila strain 130b possesses a unique combination of type IV secretion systems and novel Dot/Icm secretion system effector proteins

Loss of O-Linked Protein Glycosylation in Burkholderia cenocepacia Impairs Biofilm Formation and Siderophore Activity and Alters Transcriptional Regulators

Lysosomal degradation products induce Coxiella burnetii virulence

Molecular Detection of Legionella: Moving on From mip.

Molecular pathogenesis of infections caused by Legionella pneumophila

Multiple ecto-nucleoside triphosphate diphosphohydrolases facilitate intracellular replication of Legionella pneumophila

Murine Alveolar Macrophages Are Highly Susceptible to Replication of Coxiella burnetii Phase II In Vitro

Near-unity nuclear polarization with an open-source 129Xe hyperpolarizer for NMR and MRI.

Post-modern pathogens: surprising activities of translocated effectors from E. coli and Legionella

Proteomic identification of Coxiella burnetii effector proteins targeted to the host cell mitochondria during infection

SdrA, an NADP(H)-regenerating enzyme, is crucial for Coxiella burnetii to resist oxidative stress and replicate intracellularly

Sel1 repeat protein LpnE is a Legionella pneumophila virulence determinant that influences vacuolar trafficking

Significant role for ladC in initiation of Legionella pneumophila infection.

SopF, a phosphoinositide binding effector, promotes the stability of the nascent Salmonella-containing vacuole

Taming the Triskelion: Bacterial Manipulation of Clathrin

The Coxiella burnetii Dot/Icm System Creates a Comfortable Home through Lysosomal Renovation ⬇️

The Coxiella burnetii Dot/Icm System Delivers a Unique Repertoire of Type IV Effectors into Host Cells and Is Required for Intracellular Replication ⬇️

The Dot/Icm effector SdhA is necessary for virulence of Legionella pneumophila in Galleria mellonella and A/J mice

The Legionella pneumophila F-box protein Lpp2082 (AnkB) modulates ubiquitination of the host protein parvin B and promotes intracellular replication.

The multifunctional enzyme S-adenosylhomocysteine/methylthioadenosine nucleosidase is a key metabolic enzyme in the virulence of Salmonella enterica var Typhimurium

The role of Rab GTPases in the transport of vacuoles containingLegionella pneumophilaandCoxiella burnetii ⬇️

The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-kappaB p65.

Two novel point mutations in clinical Staphylococcus aureus reduce linezolid susceptibility and switch on the stringent response to promote persistent infection

XeNA: an automated 'open-source' (129)Xe hyperpolarizer for clinical use