Search filters

List of works by Jorg Taubel

A Highly Durable RNAi Therapeutic Inhibitor of PCSK9.

scientific article

A comparison of simplified lansoprazole suspension administered nasogastrically and pantoprazole administered intravenously: effects on 24-h intragastric pH.

scientific article published in November 2001

A nonparametric approach to QT interval correction for heart rate.

scientific article published on May 2010

A pan-European registration system for volunteer participation is within sight

scientific article published on 29 July 2012

Analyzing the relationship of QT interval and exposure to nitazoxanide, a prospective candidate for influenza antiviral therapy--A formal TQT study

scientific article published on 15 April 2014

Bupivacaine extended release liposome injection does not prolong QTc interval in a thorough QT/QTc study in healthy volunteers

scientific article published on 4 November 2011

Cardiac Safety of Rupatadine in a Single-Ascending-Dose and Multiple-Ascending-Dose Study in Healthy Japanese Subjects, Using Intensive Electrocardiogram Assessments-Comparison With the Previous White Caucasian Thorough QT Study.

scientific article

Cizolirtine citrate (E-4018) in the treatment of chronic neuropathic pain

scientific article published on 01 January 2001

Comparison of Digital 12-Lead ECG and Digital 12-Lead Holter ECG Recordings in Healthy Male Subjects: Results from a Randomized, Double-Blinded, Placebo-Controlled Clinical Trial.

scientific article

Comparison of six commonly used QT correction models and their parameter estimation methods.

scientific article published on January 2012

Comparison of the effects of levofloxacin on QT/QTc interval assessed in both healthy Japanese and Caucasian subjects ⬇️

scientific article published on March 1, 2012

Comparison of the effects of single and repeated oral doses of lansoprazole and rabeprazole on ambulatory 24-hour intragastric pH in healthy volunteers

scientific article published on 01 January 2006

Concentration-effect modeling based on change from baseline to assess the prolonging effect of drugs on QTc together with an estimate of the circadian time course

scientific article published on 27 June 2014

Estimation of the Power of the Food Effect on QTc to Show Assay Sensitivity

scientific article published on 17 August 2017

Insulin at normal physiological levels does not prolong QT(c) interval in thorough QT studies performed in healthy volunteers

scientific article published on February 2013

Lamotrigine does not prolong QTc in a thorough QT/QTc study in healthy subjects.

scientific article published on 23 July 2008

Pharmacodynamic consequences of administration of VLA-4 antagonist CDP323 to multiple sclerosis subjects: a randomized, double-blind phase 1/2 study

scientific article

Pharmacokinetics and Pharmacodynamics of Lomitapide in Japanese Subjects

scientific article published on 18 December 2015

Pharmacokinetics, Safety and Cognitive Function Profile of Rupatadine 10, 20 and 40 mg in Healthy Japanese Subjects: A Randomised Placebo-Controlled Trial.

scientific article

Repeated supratherapeutic dosing of strontium ranelate over 15 days does not prolong QT(c) interval in healthy volunteers.

scientific article published on August 2012

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Rising TAK-438 (Vonoprazan) Doses in Healthy Male Japanese/non-Japanese Subjects

scientific article

Shortening of the QT Interval After Food Can Be Used to Demonstrate Assay Sensitivity in Thorough QT Studies ⬇️

scientific article published on November 8, 2011

Single Doses up to 800 mg of E-52862 Do Not Prolong the QTc Interval--A Retrospective Validation by Pharmacokinetic-Pharmacodynamic Modelling of Electrocardiography Data Utilising the Effects of a Meal on QTc to Demonstrate ECG Assay Sensitivity

scientific article

Stability of the Effect of a Standardized Meal on QTc.

scientific article

The Power of Phase I Studies to Detect Clinical Relevant QTc Prolongation: A Resampling Simulation Study.

scientific article published on 5 October 2015

The effects of steady-state erythromycin and azithromycin on the pharmacokinetics of sildenafil in healthy volunteers.

scientific article published on January 2002

The practical application of adaptive study design in early phase clinical trials: a retrospective analysis of time savings

scientific article published on 25 November 2011

The reproducibility of QTc changes after meal intake

scientific article published on 15 November 2014

The suppression of gastro-oesophageal reflux by alginates

scientific article published on 06 August 2007

Thorough QT study of the effect of intravenous amisulpride on QTc interval in Caucasian and Japanese healthy subjects.

scientific article published on 12 September 2016

Thorough QT study of the effect of oral moxifloxacin on QTc interval in the fed and fasted state in healthy Japanese and Caucasian subjects

scientific article

Three steps to writing adaptive study protocols in the early phase clinical development of new medicines

scientific article

Time of the Day and Magnitude of the Effect of a Drug on the QTc Interval

scientific article published on 31 January 2017

Tolerability and pharmacokinetics of ACT-280778, a novel nondihydropyridine dual L/T-type calcium channel blocker: early clinical studies in healthy male subjects using adaptive designs

scientific article published on 01 February 2014

XXIV World Allergy Congress 2015: Seoul, Korea. 14-17 October 2015

scientific article published in 2016

Paulina is supported by:

About Paulina

Help