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List of works by Steven Staelens

(99)mTc-(CO)(3) His-annexin A5 micro-SPECT demonstrates increased cell death by irinotecan during the vascular normalization window caused by bevacizumab

scientific article

18F-FDG PET, the early phases and the delivery rate of 18F-AV45 PET as proxies of cerebral blood flow in Alzheimer's disease: Validation against 15O-H2O PET

scientific article published on 09 August 2019

18F-Flortanidazole Hypoxia PET Holds Promise as a Prognostic and Predictive Imaging Biomarker in a Lung Cancer Xenograft Model Treated with Metformin and Radiotherapy

scientific article published on 06 July 2018

99mTc-Duramycin SPECT Imaging of Early Tumor Response to Targeted Therapy: A Comparison with 18F-FDG PET.

scientific article published on 22 November 2016

A penalized Algebraic Reconstruction Technique (pART) for PET image reconstruction

scholarly article published 2007

A simulation study on the impact of the blood flow-dependent component in [18F]AV45 SUVR in Alzheimer's disease

scientific article published on 6 December 2017

A three-dimensional theoretical model incorporating spatial detection uncertainty in continuous detector PET.

scientific article published in June 2004

A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

scientific article published on 14 August 2011

A20 (TNFAIP3) deficiency in myeloid cells triggers rheumatoid arthritis

scholarly article by D. Elewaut et al published 22 February 2011 in Annals of the Rheumatic Diseases

Absence of cardiovascular manifestations in a haploinsufficient Tgfbr1 mouse model

scientific article

Accelerated high-frequency repetitive transcranial magnetic stimulation enhances motor activity in rats.

scientific article published on 09 February 2017

Acceleration of GATE SPECT simulations

scientific article published on April 2008

Acceleration of GATE SPECT simulations

Accurate Monte Carlo modelling of the back compartments of SPECT cameras

scientific article published on 30 November 2010

Accurate epileptogenic focus localization through time-variant functional connectivity analysis of intracranial electroencephalographic signals.

scientific article published on 18 February 2011

Acute Ketamine Infusion in Rat Does Not Affect In Vivo [C]ABP688 Binding to Metabotropic Glutamate Receptor Subtype 5

scientific article published on 01 January 2018

An integrated framework to quantitatively link mouse-specific hemodynamics to aneurysm formation in angiotensin II-infused ApoE -/- mice

scientific article

An investigation of temporal regularization techniques for dynamic PET reconstructions using temporal splines

scientific article published in May 2007

Analytical model for Solstice detector response

Antitumour efficacy of two paclitaxel formulations for hyperthermic intraperitoneal chemotherapy (HIPEC) in an in vivo rat model

scientific article published on 18 March 2011

Association of short-term cognitive decline and MCI-to-AD dementia conversion with CSF, MRI, amyloid- and F-FDG-PET imaging

scientific article published on 13 March 2019

Automated identification of ERP peaks through Dynamic Time Warping: an application to developmental dyslexia.

scientific article published on 3 September 2009

Awake 18F-FDG PET Imaging of Memantine-Induced Brain Activation and Test-Retest in Freely Running Mice.

scientific article published on 15 November 2018

Baseline [(18)F]FMISO μPET as a Predictive Biomarker for Response to HIF-1α Inhibition Combined with 5-FU Chemotherapy in a Human Colorectal Cancer Xenograft Model

scientific article

Brain inflammation in a chronic epilepsy model: Evolving pattern of the translocator protein during epileptogenesis

scientific article published on 17 September 2015

Caspase-3 probes for PET imaging of apoptotic tumor response to anticancer therapy

scientific article published on 01 May 2019

Characterization of [(99m)Tc]Duramycin as a SPECT Imaging Agent for Early Assessment of Tumor Apoptosis

scientific article

Characterization of an Orthotopic Colorectal Cancer Mouse Model and Its Feasibility for Accurate Quantification in Positron Emission Tomography

scientific article published on 13 February 2017

Characterization of the ringing artifacts in rotator-based reconstruction with Monte Carlo-based resolution compensation for PET.

scientific article published in September 2010

Cluster computing software for GATE simulations

scientific article published in June 2007

Coadministration of a Gloriosa superba extract improves the in vivo antitumoural activity of gemcitabine in a murine pancreatic tumour model

scientific article published in August 2016

Colonoscopy and µPET/CT are Valid Techniques to Monitor Inflammation in the Adoptive Transfer Colitis Model in Mice

article

Comparing planar image quality of rotating slat and parallel hole collimation: influence of system modeling

scientific article published on 20 March 2008

Comparison of image quality of different iodine isotopes (I-123, I-124, and I-131)

scientific article (publication date: June 2007)

Continuous flushing of the bladder in rodents reduces artifacts and improves quantification in molecular imaging

scientific article published in January 2014

Contrast noise behaviour of a rotating slat collimated gamma camera

Correction for partial volume effects in brain perfusion ECT imaging

Decreased levels of active uPA and KLK8 assessed by [111 In]MICA-401 binding correlate with the seizure burden in an animal model of temporal lobe epilepsy

scientific article

Deep brain stimulation of the prelimbic medial prefrontal cortex: quantification of the effect on glucose metabolism in the rat brain using [(18) F]FDG microPET.

scientific article published in December 2014

Degradation of myocardial perfusion SPECT images caused by contaminants in thallous (201Tl) chloride

scientific article

Design of a high resolution scintillator based SPECT detector (SPECTatress)

Development of a ligand for in vivo imaging of mutant huntingtin in Huntington’s disease

scientific article published in 2022

Development of a novel antibody-tetrazine conjugate for bioorthogonal pretargeting

scientific article published on 19 July 2016

Dipole estimation errors due to not incorporating anisotropic conductivities in realistic head models for EEG source analysis.

scientific article published on 24 September 2009

Early Prediction of Tumor Response to Treatment: Preclinical Validation of 99mTc-Duramycin

scientific article published on 2 February 2016

Effect of cyclosporin A administration on the biodistribution and multipinhole muSPECT imaging of [123I]R91150 in rodent brain

scientific article

Effect of geometrical constraints on PET performance in whole body simultaneous PET-MR

Effect of the static magnetic field of the MR-scanner on ERPs: evaluation of visual, cognitive and motor potentials

scientific article published on 25 January 2010

Effects of metformin on tumor hypoxia and radiotherapy efficacy: a [18F]HX4 PET imaging study in colorectal cancer xenografts

scientific article published on 02 August 2019

Efficacy Screening of Gloriosa Superba Extracts in a Murine Pancreatic Cancer Model Using (18)F-FDG PET/CT for Monitoring Treatment Response

scientific article published in April 2016

Erratum to: Preclinical Comparison of the Amyloid-β Radioligands [11C]Pittsburgh compound B and [18F]florbetaben in Aged APPPS1-21 and BRI1-42 Mouse Models of Cerebral Amyloidosis

scholarly article published in Molecular Imaging and Biology

Estimation of and correction for finite motion sampling errors in small animal PET rigid motion correction

scientific article published on 22 September 2018

Evaluation of 3D Monte Carlo-based scatter correction for 201Tl cardiac perfusion SPECT.

scientific article published in April 2007

Evaluation of 3D Monte Carlo-based scatter correction for 99mTc cardiac perfusion SPECT.

scientific article published in October 2006

Evaluation of Small-Animal PET Outcome Measures to Detect Disease Modification Induced by BACE Inhibition in a Transgenic Mouse Model of Alzheimer Disease

scientific article published on 13 June 2017

Evaluation of [18 F]BR420 and [18 F]BR351 as radiotracers for MMP-9 imaging in colorectal cancer

scientific article published on 21 December 2016

Evaluation of [18F]CP18 as a Substrate-Based Apoptosis Imaging Agent for the Assessment of Early Treatment Response in Oncology

scientific article

Evaluation of [18F]Fluorothymidine as a Biomarker for Early Therapy Response in a Mouse Model of Colorectal Cancer

scientific article published on 20 June 2016

Evolution of the GATE project: new results and developments

FIRST RESULTS WITH THE CLEARPET SMALL ANIMAL PET SCANNERS

Fan beam forced detection in Gate

Fast 3D iterative image reconstruction for SPECT with rotating slat collimators

scientific article published on 9 January 2009

Fast and Accurate Rat Head Motion Tracking With Point Sources for Awake Brain PET.

scientific article published on 13 February 2017

Fast and memory-efficient Monte Carlo-based image reconstruction for whole-body PET.

scientific article

Fast hybrid SPECT simulation including efficient septal penetration modelling (SP-PSF).

scientific article published on 8 May 2007

Fast simulation of yttrium-90 bremsstrahlung photons with GATE.

scientific article published on June 2010

GATE simulations for optimization of pinhole imaging

GATE: Improving the computational efficiency

GATE: a simulation toolkit for PET and SPECT.

scientific article

Geometrical importance sampling and pulse height tallies in GATE.

scientific article published in January 2004

Glutaminase activity in GLS1 Het mouse brain compared to putative pharmacological inhibition by ebselen using ex vivo MRS

scientific article published on 19 July 2019

High resolution μSPECT for brain activation analysis in small animals

Hippocampal deep brain stimulation induces decreased rCBF in the hippocampal formation of the rat.

scientific article published on 13 April 2010

How to Modulate Tumor Hypoxia for Preclinical In Vivo Imaging Research

scientific article published on 18 October 2018

Hybrid scatter correction applied to quantitative holmium-166 SPECT.

scientific article published on 8 September 2006

Ictal-onset localization through connectivity analysis of intracranial EEG signals in patients with refractory epilepsy

scientific article published on 3 May 2013

Imaging brain inflammation in epilepsy

scientific article

In Vivo Amyloid-β Imaging in the APPPS1-21 Transgenic Mouse Model with a (89)Zr-Labeled Monoclonal Antibody

scientific article published on 31 March 2016

In Vivo Preclinical Molecular Imaging of Repeated Exposure to an N-methyl-d-aspartate Antagonist and a Glutaminase Inhibitor as Potential Glutamatergic Modulators

scientific article published on 14 December 2018

In vitro and in vivo evaluation of [99mTc]-labeled tricarbonyl His-annexin A5 as an imaging agent for the detection of phosphatidylserine-expressing cells.

scientific article published on 20 September 2010

In vivo evaluation of (18)F-labeled TCO for pre-targeted PET imaging in the brain

scientific article published on 2 April 2014

In vivo evaluation of [123I]-4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(4-iodobenzyl)piperidine, an iodinated SPECT tracer for imaging the P-gp transporter

scientific article published on 7 April 2010

In vivo imaging of 89Zr-labeled poly(2-ethyl-2-oxazoline)s and poly(ethylene glycol)s

In vivo molecular neuroimaging of glucose utilization and its association with fibrillar amyloid-β load in aged APPPS1-21 mice

scientific article

Influence of skull conductivity perturbations on EEG dipole source analysis.

scientific article published in August 2010

Influence of skull modeling approaches on EEG source localization

scientific article published on 4 September 2013

Iterative CT Reconstruction Using Shearlet-Based Regularization

Iterative CT reconstruction using shearlet-based regularization

Kinetics of angiogenic changes in a new mouse model for hepatocellular carcinoma

scientific article

LROC assessment of non-linear filtering methods in Ga-67 SPECT imaging

Longitudinal Characterization of [18F]-FDG and [18F]-AV45 Uptake in the Double Transgenic TASTPM Mouse Model

scientific article published on 25 November 2016

Longitudinal Characterization of mGluR5 Using 11C-ABP688 PET Imaging in the Q175 Mouse Model of Huntington Disease

scientific article published on 24 May 2018

Longitudinal quantification of inflammation in the murine dextran sodium sulfate-induced colitis model using μPET/CT.

scientific article published on 16 December 2010

Low-dose micro-CT imaging for vascular segmentation and analysis using sparse-view acquisitions

scientific article

MR-based spatial normalization improves [18F]MNI-659 PET regional quantification and detectability of disease effect in the Q175 mouse model of Huntington's disease

scientific article published in PLoS ONE

Markerless rat head motion tracking using structured light for brain PET imaging of unrestrained awake small animals

scientific article published on 19 January 2017

Measurement of porto-systemic shunting in mice by novel three-dimensional micro-single photon emission computed tomography imaging enabling longitudinal follow-up

scientific article

MicroPET Outperforms Beta-Microprobes in Determining Neuroreceptor Availability under Pharmacological Restriction for Cold Mass Occupancy

scientific article published on 10 February 2017

Molecular Imaging of mGluR5 Availability with [11C]ABP68 in Glutaminase Heterozygous Mice

scientific article published on 14 December 2018

Monte Carlo simulation in PET and SPECT instrumentation using GATE

Monte Carlo simulations of a scintillation camera using GATE: validation and application modelling

scientific article published on September 2003

Multiprobe molecular imaging of an NMDA receptor hypofunction rat model for glutamatergic dysfunction

scientific article

N-acetylcysteine- and MK-801-induced changes in glutamate levels do not affect in vivo binding of metabotropic glutamate 5 receptor radioligand 11C-ABP688 in rat brain

scientific article published on 19 September 2013

Neural substrates of conversion deafness in a cochlear implant patient: a molecular imaging study using H₂¹⁵O-PET.

scientific article

Neuroimaging of Subacute Brain Inflammation and Microstructural Changes Predicts Long-Term Functional Outcome after Experimental Traumatic Brain Injury

scientific article published on 03 October 2018

Neuroreceptor kinetics in rats repeatedly exposed to quinpirole as a model for OCD

scientific article published on 07 March 2019

Non-invasive PET imaging of brain inflammation at disease onset predicts spontaneous recurrent seizures and reflects comorbidities

scientific article published on 22 December 2016

Noninvasive Relative Quantification of [11C]ABP688 PET Imaging in Mice Versus an Input Function Measured Over an Arteriovenous Shunt.

scientific article published on 29 June 2018

Noninvasive whole-body imaging of phosphatidylethanolamine as a cell death marker using 99mTc-duramycin during TNF-induced SIRS.

scientific article published in February 2018

Optimization of temporal basis functions in dynamic PET imaging

PET imaging of freely moving interacting rats

scientific article published on 02 March 2019

Performance Characterization of an Actively Cooled Repetitive Transcranial Magnetic Stimulation Coil for the Rat.

scientific article published on 5 February 2016

Performance evaluation of small-animal multipinhole μSPECT scanners for mouse imaging

scientific article published on 24 January 2013

Physics process level discrimination of detections for GATE: assessment of contamination in SPECT and spurious activity in PET.

scientific article

Preclinical Comparison of the Amyloid-β Radioligands [(11)C]Pittsburgh compound B and [(18)F]florbetaben in Aged APPPS1-21 and BRI1-42 Mouse Models of Cerebral Amyloidosis

scientific article published on 21 February 2015

Preclinical evaluation of [111 In]MICA-401, an activity-based probe for SPECT imaging of in vivo uPA activity

scientific article

Preclinical evaluation of monoclonal antibody 14C5 for targeting pancreatic cancer

scientific article

Preclinical molecular imaging of glutamatergic and dopaminergic neuroreceptor kinetics in obsessive compulsive disorder

scientific article published on 29 March 2017

Prelimbic Cortical Injections of a GABA Agonist and Antagonist: In Vivo Quantification of the Effect in the Rat Brain Using [(18)F] FDG MicroPET.

scientific article

Quantifying the effect of repetitive transcranial magnetic stimulation in the rat brain by μSPECT CBF scans

scientific article published on 30 October 2012

Quantitative μPET Imaging of Cerebral Glucose Metabolism and Amyloidosis in the TASTPM Double Transgenic Mouse Model of Alzheimer's Disease

scientific article

Radiosynthesis and in vivo evaluation of [11C]-labelled pyrrole-2-carboxamide derivates as novel radioligands for PET imaging of monoamine oxidase A.

scientific article published on 8 April 2010

Rat Brain Normalization Templates for Robust Regional Analysis of [11C]ABP688 Positron Emission Tomography/Computed Tomography

scientific article published in January 2015

Reconstruction for Gated Dynamic Cardiac PET Imaging Using a Tensor Product Spline Basis

Reconstruction of 2D PET data with Monte Carlo generated system matrix for generalized natural pixels

scientific article

Removal of the ballistocardiographic artifact from EEG-fMRI data: a canonical correlation approach

scientific article

Replacing vascular corrosion casting by in vivo micro-CT imaging for building 3D cardiovascular models in mice

scientific article

Resting-state functional MRI and [18F]-FDG PET demonstrate differences in neuronal activity between commonly used mouse strains

scientific article published on 28 October 2015

SPECT imaging of high energy isotopes and isotopes with high energy contaminants with rotating slat collimators

scientific article published in September 2009

Scatter effects of MR components in PET-MR inserts

Sensitivity of SPECT with rotating slat collimators

Simulation of complex geometries in GATE

Simulation study comparing the imaging performance of a solid state detector with a rotating slat collimator versus parallel beam collimator setups

Single-Photon Emission Computed Tomographic Imaging of the Early Time Course of Therapy-Induced Cell Death Using Technetium 99m Tricarbonyl His-Annexin A5 in a Colorectal Cancer Xenograft Model

Small-animal repetitive transcranial magnetic stimulation combined with [¹⁸F]-FDG microPET to quantify the neuromodulation effect in the rat brain

scientific article published on 27 June 2014

State-associated changes in longitudinal [18F]-PBR111 TSPO PET imaging of psychosis patients: Evidence for the accelerated ageing hypothesis?

scientific article published on 29 November 2018

Subspace electrode selection methodology for the reduction of the effect of uncertain conductivity values in the EEG dipole localization: a simulation study using a patient-specific head model

scientific article published on 16 March 2012

Synthesis and Evaluation of a Zr-89-Labeled Monoclonal Antibody for Immuno-PET Imaging of Amyloid-β Deposition in the Brain

scientific article published on 4 February 2016

Synthesis and in vivo preclinical evaluation of an (18)F labeled uPA inhibitor as a potential PET imaging agent

scientific article published on 29 March 2014

Synthesis and preclinical evaluation of an 18F labeled PDE7 inhibitor for PET neuroimaging

scientific article published on 29 July 2015

System characteristics of SPECT with a slat collimated strip detector

scientific article published on 4 January 2006

TSPO PET upregulation predicts epileptic phenotype at disease onset independently from chronic TSPO expression in a rat model of temporal lobe epilepsy

scientific article published on 28 May 2021

The Cerebrospinal Fluid Aβ1-42/Aβ1-40 Ratio Improves Concordance with Amyloid-PET for Diagnosing Alzheimer's Disease in a Clinical Setting

scientific article published on September 2017

The Effects of Physiological and Methodological Determinants on 18F-FDG Mouse Brain Imaging Exemplified in a Double Transgenic Alzheimer Model

scientific article

The Label Matters: μPET Imaging of the Biodistribution of Low Molar Mass 89Zr and 18F-Labeled Poly(2-ethyl-2-oxazoline).

scientific article published on 2 December 2016

The [18F]FDG μPET readout of a brain activation model to evaluate the metabotropic glutamate receptor 2 positive allosteric modulator JNJ-42153605.

scientific article published on 4 June 2014

The effect of occipital nerve field stimulation on the descending pain pathway in patients with fibromyalgia: a water PET and EEG imaging study

scientific article published on 12 November 2018

The geometric transfer function for a slat collimator mounted on a strip detector

The heterozygous Lemd3 +/GT mouse is not a murine model for osteopoikilosis in humans

scientific article published on 28 October 2009

Theoretical LOR model incorporating spatial uncertainty in continuous detector PET

Tomographic image quality of rotating slat versus parallel hole-collimated SPECT.

scientific article published on 25 October 2011

Towards a reproducible protocol for repetitive and semi-quantitative rat brain imaging with (18) F-FDG: exemplified in a memantine pharmacological challenge

scientific article published on 13 April 2014

Transmission imaging with a moving point source: influence of crystal thickness and collimator type

Transmission imaging with a moving point source: influence of crystal thickness and collimator type

U-SPECT-II: An Ultra-High-Resolution Device for Molecular Small-Animal Imaging

scientific article published on 16 March 2009

Use of a Ray-Based Reconstruction Algorithm to Accurately Quantify Preclinical MicroSPECT Images

Use of the GATE Monte Carlo package for dosimetry applications

Validation and noninvasive kinetic modeling of [11C]UCB-J PET imaging in mice

scientific article published on 15 July 2019

Validation of the GATE Monte Carlo simulation platform for modelling a CsI(Tl) scintillation camera dedicated to small-animal imaging.

scientific article published in January 2004

Validation of the Semiquantitative Static SUVR Method for 18F-AV45 PET by Pharmacokinetic Modeling with an Arterial Input Function

scientific article published on 23 March 2017

[18F]-FDG PET neuroimaging in rats with quinpirole-induced checking behavior as a model for obsessive compulsive disorder

scientific article published on 15 October 2016

[18F]PBR111 PET Imaging in Healthy Controls and Schizophrenia: Test - Retest Reproducibility and Quantification of Neuroinflammation.

scientific article published on 11 January 2018

[99mTc]duramycin for cell death imaging: Impact of kit formulation, purification and species difference

scientific article published on 14 September 2017

μPET imaging of the pharmacokinetic behavior of medium and high molar mass (89)Zr-labeled poly(2-ethyl-2-oxazoline) in comparison to poly(ethylene glycol).

scientific article published on 25 May 2016