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List of works by Pierre-Louis Tharaux

A Novel Extrinsic Pathway for the Unfolded Protein Response in the Kidney

scientific article published on 28 January 2016

A novel role for myeloid endothelin-B receptors in hypertension

scientific article published on 01 March 2019

Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1.

scientific article

Amphiregulin Aggravates Glomerulonephritis via Recruitment and Activation of Myeloid Cells

scientific article published on 02 July 2020

Analysis of Uncoupling Protein 2-Deficient Mice upon Anaesthesia and Sedation Revealed a Role for UCP2 in Locomotion ⬇️

scientific article published on August 10, 2012

Angiogenin Mediates Cell-Autonomous Translational Control under Endoplasmic Reticulum Stress and Attenuates Kidney Injury

scientific article published on 20 July 2015

Autophagy in kidney disease and aging: lessons from rodent models

scientific article

Cardiac Metabolic Deregulation Induced by the Tyrosine Kinase Receptor Inhibitor Sunitinib is rescued by Endothelin Receptor Antagonism

scientific article published on 8 July 2017

Cell-derived microparticles and sickle cell disease chronic vasculopathy in sub-Saharan Africa: A multinational study

scientific article published on 29 November 2020

Cellular regeneration of podocytes from parietal cells: the debate is still open

scientific article published on 01 September 2019

Circulating cell membrane microparticles transfer heme to endothelial cells and trigger vasoocclusions in sickle cell disease

scientific article published on 31 March 2015

Correction to Multifunctional Rare-Earth Vanadate Nanoparticles: Luminescent Labels, Oxidant Sensors, and MRI Contrast Agents

scientific article published on 06 April 2015

Delayed Healing of Sickle Cell Ulcers Is due to Impaired Angiogenesis and CXCL12 Secretion in Skin Wounds

scientific article published on 18 November 2015

Differential association between inflammatory cytokines and multiorgan dysfunction in COVID-19 patients with obesity

scientific article published on 26 May 2021

Direct action of endothelin-1 on podocytes promotes diabetic glomerulosclerosis

scientific article published on 10 April 2014

Early renal damage in patients with sickle cell disease in sub-Saharan Africa: a multinational, prospective, cross-sectional study

scientific article published on 28 October 2014

Effect of sleep apnea syndrome on the vascular endothelium

scientific article published in November 2003

Efficacy of the endothelin receptor blocker bosentan for refractory sickle cell leg ulcers.

scientific article published on 29 July 2008

Efficient second-harmonic imaging of collagen in histological slides using Bessel beam excitation

scientific article

Endothelial Epas1 Deficiency Is Sufficient To Promote Parietal Epithelial Cell Activation and FSGS in Experimental Hypertension.

scientific article published on 19 September 2017

Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis.

scientific article

Endothelin and podocyte injury in chronic kidney disease

scientific article published on August 30, 2011

Endothelin and the podocyte

scientific article

Endothelin in renal injury due to sickle cell disease

scientific article published on August 30, 2011

Endothelin receptor antagonism prevents hypoxia-induced mortality and morbidity in a mouse model of sickle-cell disease.

scientific article

Endothelin, renal diseases, and hypertension.

scientific article

Endothelin-1 Induces Proteinuria by Heparanase-Mediated Disruption of the Glomerular Glycocalyx

scientific article

Endothelium-Neutrophil Communication via B1-Kinin Receptor-Bearing Microvesicles in Vasculitis

scientific article published on 14 July 2017

Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis

scientific article

Epidermal growth factor: a new therapeutic target in glomerular disease ⬇️

scientific article published on April 1, 2012

Erratum: Efficient second-harmonic imaging of collagen in histological slides using Bessel beam excitation

scientific article published on 25 August 2016

Erratum: Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis

scholarly article published in Nature Medicine

Evidence for functional ANP receptors in cultured alveolar type II cells

scientific article published on 01 February 1998

Exploring type I angiotensin (AT1) receptor functions through gene targeting.

scientific article published in August 2004

FIBER-ML, an Open-Source Supervised Machine Learning Tool for Quantification of Fibrosis in Tissue Sections

scientific article published in 2022

French Intensive Care Society, International congress - Réanimation 2016

scientific article published in June 2016

Genetic and pharmacological inhibition of microRNA-92a maintains podocyte cell cycle quiescence and limits crescentic glomerulonephritis

scientific article published on 28 November 2017

Genetic background-dependent thrombotic microangiopathy is related to vascular endothelial growth factor receptor 2 signaling during anti-glomerular basement membrane glomerulonephritis in mice.

scientific article

Glomerular hyperfiltration in adult sickle cell anemia: a frequent hemolysis associated feature

scientific article

Heparin binding EGF is necessary for vasospastic response to endothelin.

scientific article published on 28 July 2006

Histamine provides an original vista on cardiorenal syndrome

scientific article published on 02 March 2020

Hmox1 Deficiency Sensitizes Mice to Peroxynitrite Formation and Diabetic Glomerular Microvascular Injuries

scientific article

How Is Proteinuric Diabetic Nephropathy Caused by Disturbed Proteostasis and Autophagy in Podocytes?

scientific article published in March 2016

How many ways can a podocyte die?

scientific article published on July 2012

Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients

scientific article published on 13 July 2020

Inhibition of Bromodomain and Extraterminal Domain Family Proteins Ameliorates Experimental Renal Damage.

scientific article

Interest and limits of in vitro studies in renal vascular endocrinology

scientific article published on 01 December 1996

L22. Crescent formation: Unraveling local mediators that break glomerular epithelial cell tolerance to immune injury ⬇️

scientific article published on 06 March 2013

Lutheran/basal cell adhesion molecule accelerates progression of crescentic glomerulonephritis in mice

scientific article

Mechanisms mediating the renal profibrotic actions of vasoactive peptides in transgenic mice.

scientific article

Multifunctional rare-Earth vanadate nanoparticles: luminescent labels, oxidant sensors, and MRI contrast agents.

scientific article published on 20 October 2014

Murine platelet production is suppressed by S1P release in the hematopoietic niche, not facilitated by blood S1P sensing

scientific article published on 01 June 2019

Nuclear Factor Erythroid 2-Related Factor 2 Drives Podocyte-Specific Expression of Peroxisome Proliferator-Activated Receptor γ Essential for Resistance to Crescentic GN

scientific article

Nuclear receptors in podocyte biology and glomerular disease

scientific article published on 17 September 2020

Platelet and Erythrocyte Sources of S1P Are Redundant for Vascular Development and Homeostasis, but Both Rendered Essential After Plasma S1P Depletion in Anaphylactic Shock. ⬇️

scientific article published on 31 August 2016

Podocyte-Specific Deletion of Murine CXADR Does Not Impair Podocyte Development, Function or Stress Response

scientific article (publication date: 2015)

Podocytes maintain high basal levels of autophagy independent of mtor signaling

scientific article published on 23 December 2019

Posttranslational modifications of sickle hemoglobin in microparticles may promote injury

scientific article published on 01 June 2019

Pro-cachectic factors link experimental and human chronic kidney disease to skeletal muscle wasting programs

scientific article published on 01 June 2021

Progression and regression in renal vascular and glomerular fibrosis.

scientific article published on February 2004

Regulation of the ROS response dynamics and organization to PDGF motile stimuli revealed by single nanoparticle imaging.

scientific article published on 10 April 2014

Renal and vascular effects of S21402, a dual inhibitor of angiotensin-converting enzyme and neutral endopeptidase, in healthy subjects with hypovolemia

scientific article published in June 2002

Resolution of sickle cell disease associated inflammation and tissue damage with 17R-Resolvin D1

scientific article published on 07 November 2018

Second harmonic imaging and scoring of collagen in fibrotic tissues

scientific article published on 01 April 2007

Second harmonic microscopy to quantify renal interstitial fibrosis and arterial remodeling

scientific article published on 01 September 2008

Selective EGF-Receptor Inhibition in CD4+ T Cells Induces Anergy and Limits Atherosclerosis

scientific article

Selective EGFR (Epidermal Growth Factor Receptor) Deletion in Myeloid Cells Limits Atherosclerosis-Brief Report

scientific article published on 30 November 2017

Sickling of red blood cells through rapid oxygen exchange in microfluidic drops

scientific article published on 6 July 2010

Sildenafil Prevents Podocyte Injury via PPAR-γ-Mediated TRPC6 Inhibition.

scientific article published on 28 November 2016

Single europium-doped nanoparticles measure temporal pattern of reactive oxygen species production inside cells.

scientific article published on 9 August 2009

Spectrum of renal manifestations in sickle cell disease

scientific article

Stimulation of lymphocyte responses by angiotensin II promotes kidney injury in hypertension

scientific article published on 21 May 2008

TGF-beta activity protects against inflammatory aortic aneurysm progression and complications in angiotensin II-infused mice

scientific article published on 25 January 2010

Targeting mTOR Signaling Can Prevent the Progression of FSGS.

scientific article

Targeting signaling pathways in glomerular diseases.

scientific article published on July 2012

The endothelin B receptor plays a crucial role in the adhesion of neutrophils to the endothelium in sickle cell disease

scientific article published on 6 April 2017

The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

scientific article published on 16 May 2022

The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression

scientific article published on 24 July 2019

Transforming growth factor-alpha mediates nuclear factor kappaB activation in strained arteries

scientific article published on 20 July 2006

Transgenic Mice as a Tool to Study the Renin-Angiotensin System ⬇️

scientific article published on January 1, 2001

Transglutaminase-dependent RhoA activation and depletion by serotonin in vascular smooth muscle cells.

scientific article published on 02 December 2006

Troponin T as a marker of differentiation revealed by proteomic analysis in renal arterioles

scientific article

Update on crescentic glomerulonephritis.

scientific article

Urinary endothelin-1 as a marker of renal damage in sickle cell disease

scientific article published on 06 September 2005

Variation in natriuretic peptides and mitral flow indexes during successful ventilatory weaning: a preliminary study.

scientific article published on 3 April 2007

WITHDRAWN: Local miscommunications between glomerular cells as potential therapeutic targets for crescentic glomerulonephritides

retracted scientific article published on 01 April 2019

[EGF receptor blockade in immune cells reduces experimental atherosclerosis]

scientific article published on 01 June 2018

[Hypokalemia. Etiology, physiopathology, diagnosis, treatment]

scientific article published on 01 October 1998

[Interactions between the renin-angiotensin system, nitric oxide and endothelin]

scientific article published on 01 January 1998

[Malignant hypertension: A bright future]

scientific article published on 27 August 2019

[New approach of fibrosis by multiphoton microscopy with second harmonic generation]

scientific article published on 01 October 2006

[Proteomic analysis of proteins involved in the renal phenotype in renovascular hypertension]

scientific article published on 01 January 2004

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