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List of works by Trevor Owens

A noncognate interaction with anti-receptor antibody-activated helper T cells induces small resting murine B cells to proliferate and to secrete antibody

scientific article published on 01 March 1988

A novel microglial subset plays a key role in myelinogenesis in developing brain

scientific article published on 28 September 2017

A pathogenic role for CD8+ T cells in a spontaneous model of demyelinating disease

scientific article published on 01 August 2006

A role for adhesion molecules in contact-dependent T help for B cells ⬇️

scientific article published on 01 April 1991

A specific and sensitive method for visualization of tumor necrosis factor in the murine central nervous system

scientific article

A wonderful week of immunology in Copenhagen

scientific article published on 01 April 2013

An allospecific murine T helper clone which can help both T and B cell responses in vitro and in vivo

scientific article published in May 1984

Angiotensin AT2 receptor-induced interleukin-10 attenuates neuromyelitis optica spectrum disorder-like pathology

scientific article published on 09 July 2019

Angiotensin II Type 1 receptor (AT1) signaling in astrocytes regulates synaptic degeneration-induced leukocyte entry to the central nervous system.

scientific article published on 22 September 2010

Animal models for multiple sclerosis.

scientific article

Astrocytes and microglia express inducible nitric oxide synthase in mice with experimental allergic encephalomyelitis

scientific article published on 01 April 1997

Astrogliosis in the neonatal and adult murine brain post-trauma: elevation of inflammatory cytokines and the lack of requirement for endogenous interferon-gamma

scientific article published in May 1997

Axotomy-induced glial reactions in normal and cytokine transgenic mice.

scientific article

Blood-brain barrier disruption in CCL2 transgenic mice during pertussis toxin-induced brain inflammation

scientific article

Bone marrow-derived versus parenchymal sources of inducible nitric oxide synthase in experimental autoimmune encephalomyelitis.

scientific article published in May 2004

CCL2 recruits T cells into the brain in a CCR2-independent manner.

scientific article

CD8+ T cells in inflammatory demyelinating disease.

scientific article published on 24 October 2007

CD95–CD95L: can the brain learn from the immune system? ⬇️

scientific article published on March 1, 1998

CSF1R Stimulation Promotes Increased Neuroprotection by CD11c+ Microglia in EAE

scientific article published on 01 January 2018

Cell interactions in concanavalin A activated cation flux and DNA synthesis of mouse lymphocytes

scientific article published on 01 November 1980

Cerebrospinal fluid aquaporin-4-immunoglobulin G disrupts blood brain barrier.

scientific article

Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS.

scientific article

Chemokine expression in GKO mice (lacking interferon-gamma) with experimental autoimmune encephalomyelitis

scientific article published on 01 February 1999

Chemokine receptor expression by inflammatory T cells in EAE.

scientific article

Chemokines in experimental autoimmune encephalomyelitis and multiple sclerosis.

scientific article

Co-stimulation by anti-immunoglobulin is required for B cell activation by CD40Llow T cells

scientific article published on 01 December 1994

Comparison of microglia and infiltrating CD11c⁺ cells as antigen presenting cells for T cell proliferation and cytokine response.

scientific article published on 25 March 2014

Complement-dependent pathogenicity of brain-specific antibodies in cerebrospinal fluid.

scientific article published on 29 September 2012

Constitutive activation of extracellular signal-regulated kinase predisposes diffuse large B-cell lymphoma cell lines to CD40-mediated cell death

scientific article published on April 2006

Continued administration of ciliary neurotrophic factor protects mice from inflammatory pathology in experimental autoimmune encephalomyelitis.

scientific article

Cytokine and chemokine inter-regulation in the inflamed or injured CNS

scientific article published on 12 January 2005

Cytokine production by cells in cerebrospinal fluid during experimental allergic encephalomyelitis in SJL/J mice

scientific article

DNA strand breaks and differentiation

scientific article published on 01 March 1983

Derivation from an alloreactive T-cell line of a clone which cross-reacts with a self H2-E-restricted minor alloantigen

scientific article published on 01 May 1984

Detection and cellular localization of phospho-STAT2 in the central nervous system by immunohistochemical staining.

scientific article published in January 2013

Detection of colony-stimulating factor messenger RNA in single T cells by in situ hybridization

scientific article published on 01 May 1989

Diffusion Kurtosis Imaging maps neural damage in the EAE model of multiple sclerosis

scientific article published on 10 December 2019

Direct demonstration of the infiltration of murine central nervous system by Pgp-1/CD44high CD45RB(low) CD4+ T cells that induce experimental allergic encephalomyelitis

scientific article published in September 1992

Dynamics of oligodendrocyte responses to anterograde axonal (Wallerian) and terminal degeneration in normal and TNF-transgenic mice

scientific article

Effectors of Th1 and Th17 cells act on astrocytes and augment their neuroinflammatory properties

scientific article published on 16 October 2017

Elevated interferon gamma expression in the central nervous system of tumour necrosis factor receptor 1-deficient mice with experimental autoimmune encephalomyelitis

scientific article

Elevated interferon-gamma in CNS inflammatory disease: a potential complication for bone marrow reconstitution in MS

scientific article published on 01 August 2000

Enhanced microglial clearance of myelin debris in T cell-infiltrated central nervous system

scientific article published in August 2009

Enhanced response to antigen within lymph nodes of SJL/J mice that were protected against experimental allergic encephalomyelitis by T cell vaccination

scientific article published in April 1993

Experimental Demyelination and Axonal Loss Are Reduced in MicroRNA-146a Deficient Mice

scientific article published on 12 March 2018

Expression of astrocytic type 2 angiotensin receptor in central nervous system inflammation correlates with blood-brain barrier breakdown

scientific article published on 23 April 2010

Glutamate metabolism is down-regulated in astrocytes during experimental allergic encephalomyelitis

scientific article published in May 1997

Helper T cell lines to major and to minor histocompatibility antigens are equally effective in the regulation of B cell responses in vivo.

scientific article published in May 1984

Hypersensitivity Responses in the Central Nervous System

scientific article

IFN-gamma enhances neurogenesis in wild-type mice and in a mouse model of Alzheimer's disease

scientific article published on 7 April 2008

IFN-gamma shapes immune invasion of the central nervous system via regulation of chemokines

scientific article

IFN-gamma-induced chemokines synergize with pertussis toxin to promote T cell entry to the central nervous system.

scientific article published in June 2007

IFNgamma enhances microglial reactions to hippocampal axonal degeneration

scientific article published on 01 May 2000

Immune cell entry to the CNS--a focus for immunoregulation of EAE

article

Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice

scientific article published on 01 October 1998

Immune regulation and CNS autoimmune disease.

scientific article

Immunotherapy for multiple sclerosis: from theory to practice

scientific article published on 01 October 1996

In vivo and in vitro requirements for T-cell activation: Concordance and contrasts ⬇️

scientific article published on 01 November 1984

Increased cationic fluxes in stimulated lymphocytes of the mouse: response of enriched B- and T-cell subpopulations to B- and T-cell mitogens

scientific article published on 01 October 1980

Increased severity of experimental autoimmune encephalomyelitis, chronic macrophage/microglial reactivity, and demyelination in transgenic mice producing tumor necrosis factor-alpha in the central nervous system

scientific article published on 01 April 1997

Induction of endogenous Type I interferon within the central nervous system plays a protective role in experimental autoimmune encephalomyelitis.

scientific article published on 14 April 2015

Inflammation in the central nervous system and Th17 responses are inhibited by IFN-gamma-Induced IL-18 binding protein.

scientific article published on 19 July 2010

Influence of type I IFN signaling on anti-MOG antibody-mediated demyelination.

scientific article

Inhibition of reactive astrocytosis in established experimental autoimmune encephalomyelitis favors infiltration by myeloid cells over T cells and enhances severity of disease

scientific article

Injury-induced type I IFN signaling regulates inflammatory responses in the central nervous system

scientific article

Innate immune responses in central nervous system inflammation ⬇️

scientific article published on May 27, 2011

Innate signaling within the central nervous system recruits protective neutrophils

scientific article published on 08 January 2020

Interferon regulatory factor-7 modulates experimental autoimmune encephalomyelitis in mice.

scientific article published on 23 December 2011

Interferon-gamma confers resistance to experimental allergic encephalomyelitis

scientific article published in July 1996

Interferon-gamma in progression to chronic demyelination and neurological deficit following acute EAE

scientific article published on 01 December 1998

Interferons in the central nervous system: a few instruments play many tunes.

scientific article published on March 2014

Key metalloproteinases are expressed by specific cell types in experimental autoimmune encephalomyelitis

article

Loss rather than downregulation of CD4+ T cells as a mechanism for remission from experimental allergic encephalomyelitis

scientific article published in May 1993

MOG extracellular domain (p1-125) triggers elevated frequency of CXCR3+ CD4+ Th1 cells in the CNS of mice and induces greater incidence of severe EAE

scientific article published on 19 February 2014

Metalloproteinases control brain inflammation induced by pertussis toxin in mice overexpressing the chemokine CCL2 in the central nervous system

scientific article published in November 2006

Microglia and macrophages express tumor necrosis factor receptor p75 following middle cerebral artery occlusion in mice

scientific article published on 11 December 2006

Microglia are required for astroglial Toll-like receptor 4 response and for optimal TLR2 and TLR3 response.

scientific article published on 23 January 2012

Multiple sclerosis and immune regulatory cells

scientific article published on 01 September 2004

NF-kappaB-driven STAT2 and CCL2 expression in astrocytes in response to brain injury

scientific article published in November 2008

Neuromyelitis optica (NMO)--an autoimmune disease of the central nervous system (CNS).

scientific article published on 29 September 2010

Neuromyelitis optica-like pathology is dependent on type I interferon response.

scientific article

Neutrophils that infiltrate the central nervous system regulate T cell responses

article

Nogo-A is a reliable oligodendroglial marker in adult human and mouse CNS and in demyelinated lesions

scientific article published on 01 March 2007

PK11195 binding to the peripheral benzodiazepine receptor as a marker of microglia activation in multiple sclerosis and experimental autoimmune encephalomyelitis

scientific article published in October 1997

Participation of L3T4 in T cell activation in the absence of class II major histocompatibility complex antigens. Inhibition by anti-L3T4 antibodies is a function both of epitope density and mode of presentation of anti-receptor antibody

scientific article published on 01 April 1987

Pathologic and Protective Roles for Microglial Subsets and Bone Marrow- and Blood-Derived Myeloid Cells in Central Nervous System Inflammation

scientific article

Peripheral phosphodiesterase 4 inhibition produced by 4-[2-(3,4-Bis-difluoromethoxyphenyl)-2-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl]-3-methylpyridine-1-oxide (L-826,141) prevents experimental autoimmune encephalomyelitis

scientific article published on 29 June 2006

Production of two hemopoietic growth factors is differentially regulated in single T lymphocytes activated with an anti-T cell receptor antibody

scientific article published on 01 February 1988

Proliferating resident microglia express the stem cell antigen CD34 in response to acute neural injury

scientific article published in April 2005

Protective roles for myeloid cells in neuroinflammation

scientific article published on 27 August 2020

Reactive microgliosis engages distinct responses by microglial subpopulations after minor central nervous system injury

scientific article (publication date: 2005)

Requirement for noncognate interaction with T cells for the activation of B cell immunoglobulin secretion by IL-2 ⬇️

scientific article published on 01 April 1991

Selective enrichment of Th1 CD45RBlow CD4+ T cells in autoimmune infiltrates in experimental allergic encephalomyelitis

scientific article published on 01 March 1994

Selective localization of IgG from cerebrospinal fluid to brain parenchyma

scientific article

Signaling through MyD88 regulates leukocyte recruitment after brain injury.

scientific article published in November 2008

Signaling through intercellular adhesion molecule 1 (ICAM-1) in a B cell lymphoma line. The activation of Lyn tyrosine kinase and the mitogen-activated protein kinase pathway

scientific article published in Journal of Biological Chemistry

Specific blockade by CD54 and MHC II of CD40-mediated signaling for B cell proliferation and survival

scientific article published on 01 May 2001

Statin therapy inhibits remyelination in the central nervous system.

scientific article published on 06 April 2009

Stimulation of adult oligodendrogenesis by myelin-specific T cells

scientific article

Suppression induction in vivo by a T helper clone?

scientific article published on 01 April 1985

Suppressor T cells, distinct from "veto cells," are induced by alloantigen priming and mediate transferable suppression of cytotoxic T lymphocyte responses in vivo

scientific article published on 01 November 1985

Surfactant protein d deficiency in mice is associated with hyperphagia, altered fat deposition, insulin resistance, and increased basal endotoxemia

scientific article

T cell antigen receptor expression by subsets of Ly-2-L3T4- (CD8-CD4-) thymocytes

scientific article published in March 1988

T-cell costimulation: T cells themselves call the shots.

scientific article published on January 1996

T-dependent B-cell activation is signalled by an early increase in potassium influx.

scientific article published on August 1982

TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice

scientific article published on 19 March 2012

TNF-alpha expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis. Regulation by Th1 cytokines

scientific article published on 01 January 1995

TNFalpha: kill or cure for demyelinating disease?

scientific article

Th1 and Th2 help for B cells: differential capacity for induction of autonomous responsiveness to IL-2

scientific article published on 01 June 1995

The Presentation of Cell Surface Alloantigens to T Cells ⬇️

scientific article published on December 1, 1984

The acquisition of cytokine responsiveness by murine B cells: a role for antigen and IL-5 in the induction of IL-2 receptors

scientific article published on 01 March 1994

The attraction of adhesion molecules

scientific article published on 01 August 1993

The cation pump as a switch mechanism controlling proliferation and differentiation in lymphocytes

scientific article published on 01 August 1982

The cell biology of T-dependent B cell activation.

scientific article

The central nervous system environment controls effector CD4+ T cell cytokine profile in experimental allergic encephalomyelitis ⬇️

scientific article published on November 1, 1997

The changing face of cytokines in the brain: perspectives from EAE.

scientific article

The chemokine receptor CCR2 maintains plasmacytoid dendritic cell homeostasis

scientific article published on 26 October 2017

The complex immunology of multiple sclerosis

scientific article published on 01 July 2014

The effect of ultraviolet radiation on early stages of activation of human lymphocytes: inhibition is independent of effects on DNA

scientific article published on 01 September 1982

The murine gammaherpesvirus-68 chemokine-binding protein M3 inhibits experimental autoimmune encephalomyelitis

scientific article published on July 2010

The role of CD4 in antigen-independent activation of isolated single T lymphocytes

scientific article published on 01 October 1988

Thymic CCL2 influences induction of T-cell tolerance

scientific article published on 14 August 2014

Toll-like receptor 2 signaling in response to brain injury: an innate bridge to neuroinflammation.

scientific article published in December 2006

Toll-like receptors in brain development and homeostasis.

scientific article published on 4 September 2007

Toll-like receptors in neurodegeneration.

scientific article published on January 2009

Toll-like receptors on astrocytes: patterning for immunity

scientific article published on 20 November 2004

Type I interferon-activated microglia are critical for neuromyelitis optica pathology

scientific article published on 26 November 2020

VIth International Congress of Neuroimmunology. Edinburgh, Scotland, September 3-7, 2001.

scientific article published in March 2002

Vav-1 expression correlates with NFκB activation and CD40-mediated cell death in diffuse large B-cell lymphoma cell lines

scientific article

Veto in vivo?

scientific article published on 01 February 1985

What is microglia neurotoxicity (Not)?

scientific article published on 03 March 2014

X-linked inhibitor of apoptosis regulates T cell effector function

article

[MBP P89-101 induced experimental allergic encephalomyelitis in mice and establishment of CD4+ T cell line specific to MBP P89-101]

scientific article published on 01 June 1994

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