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List of works by Alan L. Hudson

'Seeing through a glass darkly': casting light on imidazoline 'I' sites

scientific article published in September 1998

(-)Baclofen decreases neurotransmitter release in the mammalian CNS by an action at a novel GABA receptor.

scientific article

1-[(Imidazolidin-2-yl)imino]indazole. Highly alpha 2/I1 selective agonist: synthesis, X-ray structure, and biological activity

scientific article published on 3 June 2008

2-(4,5-Dihydro-1H-imidazol-2-yl)indazole (indazim) derivatives as selective I2 imidazoline receptor ligands ⬇️

scientific article published on October 1, 2003

2-(4,5-Dihydroimidazol-2-yl)benzimidazoles as highly selective imidazoline I2/adrenergic α2 receptor ligands

scientific article published on 16 June 2006

3-[(Imidazolidin-2-yl)imino]indazole ligands with selectivity for the α2-adrenoceptor compared to the imidazoline I1 receptor

scientific article published on 11 November 2010

5-Isothiocyanato-2-benzofuranyl-2-imidazoline (BU99006) an irreversible imidazoline(2) binding site ligand: in vitro and in vivo characterisation in rat brain.

scientific article

6 -Hydroxydopamine decreases benzodiazepine but not GABA receptor binding in rat cerebellum

scientific article published in December 1981

Autoradiographic localization of GABAB receptors in rat cerebellum

scientific article published in December 1981

Autoradiographical and behavioural effects of a chronic infusion of antisense to the alpha2D-adrenoceptor in the rat.

scientific article

Autoradiographical distribution of imidazoline binding sites in monoamine oxidase A deficient mice

scientific article published on 10 February 2006

Autoradiography of I2 receptors in frog brain

scientific article

BU98008, a highly selective imidazoline(1)-receptor ligand.

scientific article published in December 2003

Bicuculline-insensitive gaba receptors on peripheral autonomic nerve terminals ⬇️

scientific article published on April 24, 1981

Binding of an imidazopyridoindole at imidazoline I2 receptors

scientific article published in January 2004

Binding of beta-carbolines at imidazoline I2 receptors: a structure-affinity investigation

scientific article published in February 2004

Bioactive contaminants leach from disposable laboratory plasticware

scientific article

Characterisation and localisation of [3H]2-(2-benzofuranyl)-2-imidazoline binding in rat brain: a selective ligand for imidazoline I2 receptors

scientific article published in July 1998

Characterisation of imidazoline I2 binding sites in pig brain

scientific article published in September 2005

Characterization of [(3)H]harmane binding to rat whole brain membranes.

scientific article published in December 2003

Comparison of alterations in c-fos and Egr-1 (zif268) expression throughout the rat brain following acute administration of different classes of antidepressant compounds.

scientific article published in July 2005

Comparison of crude methanolic CDS extracts from various tissues

scientific article

Distribution of [(3)H]BU224, a selective imidazoline I(2) binding site ligand, in rat brain

scientific article published in August 2002

Effect of harmane, an endogenous β-carboline, on learning and memory in rats.

scientific article

Effects of the beta-carbolines, harmane and pinoline, on insulin secretion from isolated human islets of Langerhans

scientific article published on December 2003

Endogenous indoleamines demonstrate moderate affinity for I2 binding sites

scientific article

Evaluation and initial in vitro and ex vivo characterization of the potential positron emission tomography ligand, BU99008 (2-(4,5-dihydro-1H-imidazol-2-yl)-1- methyl-1H-indole), for the imidazoline₂ binding site

scientific article published on 22 February 2012

Evidence that SL75102 is an agonist at GABAb as well as GABAa receptors

scientific article published in May 1982

Favourable involvement of α2A-adrenoreceptor antagonism in the I₂-imidazoline binding sites-mediated morphine analgesia enhancement

scientific article published on 13 February 2012

Fluorinated analogues of marsanidine, a highly α2-AR/imidazoline I1 binding site-selective hypotensive agent. Synthesis and biological activities

scientific article published on 28 September 2014

Functional studies of specific imidazoline-2 receptor ligands.

scientific article

GABA receptor multiplicity. Visualization of different receptor types in the mammalian CNS.

scientific article published on February 1984

GABAA and GABAB receptor site distribution in the rat central nervous system

scientific article published on 01 February 1987

Harmane and harmalan are bioactive components of classical clonidine-displacing substance.

scientific article published in December 2004

Harmane: an atypical neurotransmitter?

scientific article published on 24 January 2015

Identification of an imidazoline binding protein: creatine kinase and an imidazoline-2 binding site

scientific article published on 03 May 2009

Identification of ligands selective for central I2-imidazoline binding sites

scientific article published on 01 January 1997

Imidazoline (I2) binding sites in chicken brain

scientific article

Imidazoline binding sites in Huntington's and Parkinson's disease putamen

scientific article published in April 1996

Imidazoline2 (I2) receptor- and alpha2-adrenoceptor-mediated modulation of hypothalamic-pituitary-adrenal axis activity in control and acute restraint stressed rats

scientific article published in March 2004

In vitro and ex vivo distribution of [3H]harmane, an endogenous beta-carboline, in rat brain

scientific article published on 19 October 2005

In vitro and in vivo effect of BU99006 (5-isothiocyanato-2-benzofuranyl-2-imidazoline) on I2 binding in relation to MAO: evidence for two distinct I2 binding sites

scientific article published on 10 October 2006

In vitro and in vivo effects of antisense on alpha 2-adrenoceptor expression

scientific article published on 01 January 2000

In vivo estimation of imidazoline(2) binding site turnover.

scientific article published in December 2003

Inhibition of central monoamine oxidase by imidazoline2 site-selective ligands

scientific article

Initial evaluation of novel selective ligands for imidazoline(2) receptors in rat whole brain.

scientific article published in December 2003

Invited review: the evolution of antidepressant mechanisms

scientific article (publication date: February 2004)

Isoguvacine, isonipecotic acid, muscimol and N-methyl isoguvacine on the GABA receptor in rat sympathetic ganglia ⬇️

scientific article published on September 15, 1978

Localization of high affinity [3H]glibenclamide binding sites within the substantia nigra zona reticulata of the rat brain.

scientific article

Modulation of resistance artery tone by the trace amine β-phenylethylamine: dual indirect sympathomimetic and α1-adrenoceptor blocking actions

scientific article published on 12 August 2014

N-(Imidazolidin-2-ylidene)-1-arylmethanamine Oxides: Synthesis, Structure and Pharmacological Evaluation

scientific article published on 14 November 2011

New analogues of agmatine with higher affinity to imidazoline receptors

scientific article

New imidazoline/α(2)-adrenoceptors affecting compounds-4(5)-(2-aminoethyl)imidazoline (dihydrohistamine) derivatives. Synthesis and receptor affinity studies

scientific article published on 25 November 2010

Nonadrenergic Imidazoline Binding Sites and Amine Oxidase Activities in Fat Cells ⬇️

scientific article published on July 12, 1995

Novel imidazoline compounds as partial or full agonists of D2-like dopamine receptors inspired by I2-imidazoline binding sites ligand 2-BFI.

scientific article published on 6 August 2010

Novel ligands for the investigation of imidazoline receptors and their binding proteins.

scientific article published in December 2003

Novel ligands rationally designed for characterizing I2-imidazoline binding sites nature and functions

scientific article published on 29 July 2008

Novel selective compounds for the investigation of imidazoline receptors

scientific article

Pharmacological characterisation of novel alpha 2-adrenoceptor antagonists as potential brain imaging agents.

scientific article published in May 2004

Pharmacological characterisation of the electrically evoked release of monoamines from chicken brain in vitro

scientific article published in February 2007

Potentiation of barbiturate-induced alterations in presynaptic noradrenergic function in rat frontal cortex by imidazol(in)e alpha2-adrenoceptor agonists.

scientific article published in October 1998

Probes for imidazoline binding sites: synthesis and evaluation of a selective, irreversible I2 ligand

scientific article published on 01 March 2000

Pyrazino[1,2-a]indoles as novel high-affinity and selective imidazoline I(2) receptor ligands

scientific article published in February 2004

Quantification of in vivo binding of [3H]RX 821002 in rat brain: evaluation as a radioligand for central alpha 2-adrenoceptors.

scientific article published in November 1992

Quetiapine and Buspirone Both Elevate Cortical Levels of Noradrenaline and Dopamine In vivo, but Do Not have Synergistic Effects.

scientific article published on 14 September 2012

Selective delta-opioid receptor ligands: potential PET ligands based on naltrindole.

scientific article published in April 2001

Synthesis and biological activities of 2-[(heteroaryl)methyl]imidazolines

scientific article published on 25 November 2011

Synthesis of 2,3,5,6-tetrahydro-3H-imidazo[2,1-b] [1,3,5]benzotriazepines and their oxidative ring contraction into 1-(4,5-dihydro-1H-imidazol-2-yl)-1H-benzimidazoles

scientific article

The effect of 1-(4,5-dihydro-1H-imidazol-2-yl) isoquinoline on monoamine release and turnover in the rat frontal cortex

scientific article

The effect of 7-fluoro-marsanidine, a novel α2-adrenoceptor agonist, on extracellular noradrenaline in rat frontal cortex: a microdialysis study

scientific article published on 27 January 2015

The modulatory action of harmane on serotonergic neurotransmission in rat brain

scientific article

Thyrotropin-releasing hormone selectively reverses lorazepam-induced sedation but not slowing of saccadic eye movements

scientific article published on January 1, 1992

Transfer of SAR information from hypotensive indazole to indole derivatives acting at α-adrenergic receptors: In vitro and in vivo studies

scientific article published on 14 March 2016

[3H]2-(2-benzofuranyl)-2-imidazoline: a new selective high affinity radioligand for the study of rabbit brain imidazoline I2 receptors

scientific article published on 01 May 1996

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