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List of works by Kosei Hasegawa

A phase 2 study of intraperitoneal carboplatin plus intravenous dose-dense paclitaxel in front-line treatment of suboptimal residual ovarian cancer

scientific article published on 31 January 2020

A phase I study of farletuzumab, a humanized anti-folate receptor α monoclonal antibody, in patients with solid tumors

scientific article

Advanced Mucinous Adenocarcinoma Arising from a Mature Cystic Teratoma: A Case Report and Literature Review

scientific article

An Unusual Ovarian Mucinous Borderline Tumor with a Large Solid Component.

scientific article published on 22 May 2019

Anti-tumor activity of dual inhibition of phosphatidylinositol 3-kinase and MDM2 against clear cell ovarian carcinoma

scientific article published on 05 September 2019

Antibody-based tumor vascular theranostics targeting endosialin/TEM1 in a new mouse tumor vascular model

scientific article

Association of histone deacetylase expression with histology and prognosis of ovarian cancer

scientific article published on 4 January 2018

Association of statins, aspirin, and venous thromboembolism in women with endometrial cancer

scientific article published on 05 January 2019

Association of the hypoxia-inducible factor-1α (HIF-1α) gene polymorphisms with prognosis in ovarian clear cell carcinoma

article

Characterization of T cell repertoire of blood, tumor, and ascites in ovarian cancer patients using next generation sequencing

scientific article

Characterizing sarcoma dominance pattern in uterine carcinosarcoma: Homologous versus heterologous element

scientific article published on 11 May 2018

Clinical Trials of Neoadjuvant Chemotherapy for Ovarian Cancer: What Do We Gain After an EORTC Trial and After Two Additional Ongoing Trials Are Completed? ⬇️

scientific article published on June 1, 2013

Clinical significance of T cell clonality and expression levels of immune-related genes in endometrial cancer

scientific article

Clinical utility of CA-125 in the management of uterine carcinosarcoma

scientific article published on 01 November 2018

Clinically relevant molecular subtypes and genomic alteration-independent differentiation in gynecologic carcinosarcoma

scientific article published on 31 October 2019

Clinicopathological correlation of ARID1A status with HDAC6 and its related factors in ovarian clear cell carcinoma

scientific article published on 20 February 2019

Coexistence of endometrial mesonephric-like adenocarcinoma and endometrioid carcinoma suggests a Müllerian duct lineage: a case report.

scientific article published on 7 June 2019

Combination Therapy of Pregabalin with Tramadol for Treatment of Peripheral Neuropathy in Patients with Gynecological Cancer Receiving Taxane Containing Chemotherapy

scientific article

Contributing factors for menopausal symptoms after surgical staging for endometrial cancer

scientific article

Correction: Integrated Copy Number and Expression Analysis Identifies Profiles of Whole-Arm Chromosomal Alterations and Subgroups with Favorable Outcome in Ovarian Clear Cell Carcinomas

scientific article published on 6 July 2015

Correlation Between Tumor Mesothelin Expression and Serum Mesothelin in Patients with Epithelial Ovarian Carcinoma: A Potential Noninvasive Biomarker for Mesothelin-targeted Therapy

scientific article published on 3 February 2017

Current and future strategies for treatment of ovarian clear cell carcinoma

scientific article published on 23 June 2020

Development, optimization, and validation of novel anti-TEM1/CD248 affinity agent for optical imaging in cancer

scientific article

Effect of lymphovascular space invasion on survival of stage I epithelial ovarian cancer

scientific article

Effective screening of T cells recognizing neoantigens and construction of T-cell receptor-engineered T cells.

scientific article

Efficacy and safety of nivolumab in Japanese patients with uterine cervical cancer, uterine corpus cancer, or soft tissue sarcoma: Multicenter, open-label phase 2 trial

scientific article published on 03 September 2019

Efficacy and safety of triple therapy with aprepitant, palonosetron, and dexamethasone for preventing nausea and vomiting induced by cisplatin-based chemotherapy for gynecological cancer: KCOG-G1003 phase II trial.

scientific article published on 14 May 2014

Erratum: Pre-operative evaluation of circulating KL-6 levels as a biomarker for epithelial ovarian carcinoma and its correlation with tumor MUC1 expression

scientific article published on 23 August 2017

Estrogen receptor expression and increased risk of lymphovascular space invasion in high-grade serous ovarian carcinoma.

scientific article

Estrogen-producing endometrioid adenocarcinoma resembling sex cord-stromal tumor of the ovary: a review of four postmenopausal cases ⬇️

scientific article published on November 28, 2012

Evaluation of Circulating Tumor DNA in Patients with Ovarian Cancer Harboring Somatic PIK3CA or KRAS Mutations

scientific article published on 06 May 2020

Expression of multiple immune checkpoint molecules on T cells in malignant ascites from epithelial ovarian carcinoma

scientific article published on 21 February 2018

Feasibility study of combination chemotherapy with paclitaxel, doxorubicin and cisplatin without prophylactic granulocyte colony-stimulating factor injection for intermediate-to-high risk or recurrent endometrial cancer

scientific article

Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer

scholarly article

Genomics to immunotherapy of ovarian clear cell carcinoma: Unique opportunities for management

scientific article published on 12 September 2018

Gynecologic Cancer InterGroup (GCIG) consensus review for clear cell carcinoma of the uterine corpus and cervix.

scientific article

Gynecological Cancers Translational, Research Implementation, and Harmonization: Gynecologic Cancer InterGroup Consensus and Still Open Questions

scientific article published on 26 February 2019

High expression of maternal embryonic leucine-zipper kinase (MELK) impacts clinical outcomes in patients with ovarian cancer and its inhibition suppresses ovarian cancer cells growth ex vivo

scientific article published on 01 November 2020

Hormonal Regulation of Patient-Derived Endometrial Cancer Stem-like Cells Generated by Three-Dimensional Culture

scientific article published on 01 August 2019

Identification of novel mutations of ovarian cancer-related genes from RNA-sequencing data for Japanese epithelial ovarian cancer patients

scientific article published on 19 November 2019

Identification of serum cytokine clusters associated with outcomes in ovarian clear cell carcinoma

scientific article published on 28 October 2020

Immunogenomic landscape of gynecologic carcinosarcoma

scientific article published on 06 December 2020

Impact of TP53 immunohistochemistry on the histological grading system for endometrial endometrioid carcinoma

scientific article published on 11 February 2019

Impact of adjuvant therapy on recurrence patterns in stage I uterine carcinosarcoma

scientific article published on 16 February 2017

Impact of molecular classification on clinical management of ovarian cancer

scientific article published in February 2015

Integrated copy number and expression analysis identifies profiles of whole-arm chromosomal alterations and subgroups with favorable outcome in ovarian clear cell carcinomas

scientific article published on 4 June 2015

Integrative genomic analysis of phosphatidylinositol 3'-kinase family identifies PIK3R3 as a potential therapeutic target in epithelial ovarian cancer

scientific article published on 01 September 2007

Intravenous/Intraperitoneal Paclitaxel and Intraperitoneal Carboplatin in Patients With Epithelial Ovarian, Fallopian Tube, or Peritoneal Carcinoma: A Feasibility Study ⬇️

scientific article published on January 1, 2012

Landscape of systemic therapy for ovarian cancer in 2019: Primary therapy

scientific article published on 01 December 2019

MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53.

scientific article published on 21 September 2016

MicroRNA microarray identifies Let-7i as a novel biomarker and therapeutic target in human epithelial ovarian cancer

scientific article published on December 2008

Neoantigen load and HLA-class I expression identify a subgroup of tumors with a T-cell-inflamed phenotype and favorable prognosis in homologous recombination-proficient high-grade serous ovarian carcinoma

scientific article published on 01 May 2020

Partial Deletion of Glycoprotein B5R Enhances Vaccinia Virus Neutralization Escape while Preserving Oncolytic Function

scientific article published on 21 May 2019

Pazopanib as a second line treatment for uterine and ovarian carcinosarcoma: a single institutional study

scientific article published on January 2017

Pembrolizumab monotherapy in Japanese patients with advanced ovarian cancer: Subgroup analysis from the KEYNOTE-100

scientific article published on 03 February 2020

Phase 2 single-arm study on the efficacy and safety of niraparib in Japanese patients with heavily pretreated, homologous recombination-deficient ovarian cancer

scientific article published on 10 December 2020

Phase I Study of Multiple Epitope Peptide Vaccination in Patients With Recurrent or Persistent Cervical Cancer

scientific article published on 9 February 2018

Phase II basket trial of perifosine monotherapy for recurrent gynecologic cancer with or without PIK3CA mutations.

scientific article published on 2 September 2017

Pre-operative evaluation of circulating KL-6 levels as a biomarker for epithelial ovarian carcinoma and its correlation with tumor MUC1 expression

scientific article

Principle and evolving role of intraperitoneal chemotherapy in ovarian cancer

scientific article published on 06 August 2013

Proposal for a Risk-Based Categorization of Uterine Carcinosarcoma

scientific article published on 13 August 2018

Recurrence, death, and secondary malignancy after ovarian conservation for young women with early-stage low-grade endometrial cancer

scientific article published on 16 August 2019

Salvage chemotherapy with taxane and platinum for women with recurrent uterine carcinosarcoma.

scientific article published on 19 October 2017

Serum folate receptor alpha as a biomarker for ovarian cancer: Implications for diagnosis, prognosis and predicting its local tumor expression

scientific article

Significance of Lymphovascular Space Invasion by the Sarcomatous Component in Uterine Carcinosarcoma

scientific article published on 03 July 2018

Significance of abnormal peritoneal cytology on survival of women with stage I-II endometrioid endometrial cancer.

scientific article published on 12 March 2018

Significance of venous thromboembolism in women with uterine carcinosarcoma

scientific article published on 13 December 2017

Single nedaplatin treatment as salvage chemotherapy for platinum/taxane‐resistant/refractory epithelial ovarian, tubal and peritoneal cancers ⬇️

scientific article published on August 1, 2010

Subclinical thiamine deficiency identified by preoperative evaluation in an ovarian cancer patient: Diagnosis and the need for preoperative thiamine measurement

scientific article published on 01 October 2019

Survival outcome of stage I ovarian clear cell carcinoma with lympho-vascular space invasion.

scientific article published on 10 December 2014

Survival outcome of women with stage IV uterine carcinosarcoma who received neoadjuvant chemotherapy followed by surgery.

scientific article

Synchronous mucinous metaplasia and neoplasia of the female genital tract with external urethral meatus neoplasm: A case report

scientific article published on 17 February 2015

Systematic Identification of Characteristic Genes of Ovarian Clear Cell Carcinoma Compared with High-Grade Serous Carcinoma Based on RNA-Sequencing

scientific article published on 04 September 2019

T-LAK Cell-Originated Protein Kinase (TOPK) as a Prognostic Factor and a Potential Therapeutic Target in Ovarian Cancer

scientific article published on 22 June 2016

The Efficacy of Low-Dose Paclitaxel Added to Combination Chemotherapy of Carboplatin and Gemcitabine or Pegylated Liposomal Doxorubicin

scientific article

The Risk of Ovarian Malignancy Algorithm (ROMA) as a Predictive Marker of Peritoneal Dissemination in Epithelial Ovarian Cancer Patients.

scientific article published on 19 May 2015

The frequency of neoantigens per somatic mutation rather than overall mutational load or number of predicted neoantigens per se is a prognostic factor in ovarian clear cell carcinoma.

scientific article published on 16 June 2017

The prognostic significance of tumor lymphangiogenesis and lymphatic vessel density in endometrioid carcinoma of the uterine corpus

scientific article published on 4 September 2017

Transcriptional regulation of PIK3CA oncogene by NF-kappaB in ovarian cancer microenvironment

scientific article

Treatment Outcome of Second-Line Chemotherapy for Gynecologic Carcinosarcoma

scientific article published on 11 June 2020

Tumor characteristics and outcome of uterine carcinosarcoma in women aged ≥80 years

scientific article published on 07 February 2019

Tumor characteristics and survival outcomes of women with tamoxifen-related uterine carcinosarcoma

scientific article

Tumor-related mutations in cell-free DNA in pre-operative plasma as a prognostic indicator of recurrence in endometrial cancer

scientific article published on 21 July 2020

Venous thromboembolism, interleukin-6 and survival outcomes in patients with advanced ovarian clear cell carcinoma.

scientific article published on 31 July 2015

[I. Clinical Development and Prospect of Chemotherapy for Uterine Carcinosarcoma]

[II. Future perspectives of intraperitoneal chemotherapy for ovarian cancer]

scientific article published in February 2014

[III. Chemotherapy, Targeted Therapy and Immunotherapy for Uterine Leiomyosarcoma]

[Ⅰ.Minimally Invasive Surgery for Cervical Cancer]

scientific article published on 01 February 2019

[Ⅲ.The Current Status and Future Perspective of Chemotherapy, Targeted Therapy and Immunotherapy for Cervical Cancer]

scientific article published on 01 February 2020

lncRNA UCA1-Mediated Cdc42 Signaling Promotes Oncolytic Vaccinia Virus Cell-to-Cell Spread in Ovarian Cancer

miR-210 links hypoxia with cell cycle regulation and is deleted in human epithelial ovarian cancer

scientific article

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