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List of works by Sergey B. Zotchev

Actinomycetes from sediments in the Trondheim fjord, Norway: diversity and biological activity.

scientific article published on 23 January 2008

Activation of chloramphenicol biosynthesis in Streptomyces venezuelae ATCC 10712 by ethanol shock: insights from the promoter fusion studies. ⬇️

scientific article

Alginate Biosynthesis Factories in Pseudomonas fluorescens: Localization and Correlation with Alginate Production Level.

scientific article published on 11 December 2015

An orthogonal system for heterologous expression of actinobacterial lasso peptides in Streptomyces hosts.

scientific article published on 29 May 2018

An unexpected role for the putative 4'-phosphopantetheinyl transferase-encoding gene nysF in the regulation of nystatin biosynthesis in Streptomyces noursei ATCC 11455. ⬇️

scientific article published in August 2005

Analysis of the mycosamine biosynthesis and attachment genes in the nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455.

scientific article published on 28 September 2007

Anti-microbial and cytotoxic 1,6-dihydroxyphenazine-5,10-dioxide (iodinin) produced by Streptosporangium sp. DSM 45942 isolated from the fjord sediment.

scientific article published on 26 October 2013

Biosynthesis of deoxyaminosugars in antibiotic-producing bacteria.

scientific article published on 16 January 2004

Biosynthesis of natural products applied to drug discovery

scientific article published on 01 January 2008

Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway. ⬇️

scientific article published in June 2000

Biosynthesis of the polyene macrolide antibiotic nystatin in Streptomyces noursei.

scientific article

Biosynthetic engineering of polyene macrolides towards generation of improved antifungal and antiparasitic agents.

scientific article

Characterization of Streptomyces spp. isolated from the sea surface microlayer in the Trondheim Fjord, Norway.

scientific article published in December 2008

Characterization of a linear extrachromosomal DNA element (pBL1) isolated after interspecific mating between Streptomyces bambergiensis and S. lividans

scientific article published on 01 November 1992

Characterization of the P450 monooxygenase NysL, responsible for C-10 hydroxylation during biosynthesis of the polyene macrolide antibiotic nystatin in Streptomyces noursei.

scientific article

Chemical diversity of polyene macrolides produced by Streptomyces noursei ATCC 11455 and recombinant strain ERD44 with genetically altered polyketide synthase NysC.

scientific article published on November 2004

Chemical modification and biological evaluation of new semisynthetic derivatives of 28,29-Didehydronystatin A1 (S44HP), a genetically engineered antifungal polyene macrolide antibiotic

scientific article published in January 2009

Class IV Lasso Peptides Synergistically Induce Proliferation of Cancer Cells and Sensitize Them to Doxorubicin ⬇️

scientific article published on 10 November 2020

Cloning and Heterologous Expression of the Grecocycline Biosynthetic Gene Cluster

scientific article

Complete genome sequence of the actinomycete Actinoalloteichus hymeniacidonis type strain HPA 177T isolated from a marine sponge

scientific article published on 20 December 2016

Development of a Biosensor Concept to Detect the Production of Cluster-Specific Secondary Metabolites.

scientific article published on 21 February 2017

Engineering terpene biosynthesis in Streptomyces for production of the advanced biofuel precursor bisabolene.

scientific article published on 9 July 2014

Exploring Actinobacteria Associated With Rhizosphere and Endosphere of the Native Alpine Medicinal Plant Leontopodium nivale Subspecies alpinum

scientific article published on 08 November 2019

Genome-based bioprospecting of microbes for new therapeutics.

scientific article published on 03 May 2012

Genomics of sponge-associated Streptomyces spp. closely related to Streptomyces albus J1074: insights into marine adaptation and secondary metabolite biosynthesis potential

scientific article

Genomics-Based Insights Into the Biosynthesis and Unusually High Accumulation of Free Fatty Acids by Streptomyces sp. NP10. ⬇️

scientific article

Hexaene derivatives of nystatin produced as a result of an induced rearrangement within the nysC polyketide synthase gene in S. noursei ATCC 11455.

scientific article

Identification of a New Phosphatase Enzyme Potentially Involved in the Sugar Phosphate Stress Response in Pseudomonas fluorescens

scientific article

Identification of a gene cluster for antibacterial polyketide-derived antibiotic biosynthesis in the nystatin producer Streptomyces noursei ATCC 11455.

scientific article

Identification of a methyl-specific restriction system mediated by a conjugative element from Streptomyces bambergiensis ⬇️

scientific article published on August 1, 1995

Identification of novel genes involved in long-chain n-alkane degradation by Acinetobacter sp. strain DSM 17874.

scientific article

In vivo analysis of the regulatory genes in the nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455 reveals their differential control over antibiotic biosynthesis. ⬇️

scientific article published on March 2004

Initiation of Polyene Macrolide Biosynthesis: Interplay between Polyketide Synthase Domains and Modules as Revealed via Domain Swapping, Mutagenesis, and Heterologous Complementation ⬇️

scientific article published on 05 August 2011

Insights into the evolution of macrolactam biosynthesis through cloning and comparative analysis of the biosynthetic gene cluster for a novel macrocyclic lactam, ML-449 ⬇️

scientific article published on 23 October 2009

Isolation and characterization of the gene cluster for biosynthesis of the thiopeptide antibiotic TP-1161.

scientific article published on 17 September 2010

Marine actinomycetes as an emerging resource for the drug development pipelines.

scientific article published on 12 June 2011

Micropropagation and Cryoconservation of the Endangered Plant Species Artemisia laciniata (Asteraceae)

article

Minimum Information about a Biosynthetic Gene cluster.

scientific article published on August 2015

New Deferoxamine Glycoconjugates Produced upon Overexpression of Pathway-Specific Regulatory Gene in the Marine Sponge-Derived Streptomyces albus PVA94-07. ⬇️

scientific article published on 27 August 2016

New Nystatin-Related Antifungal Polyene Macrolides with Altered Polyol Region Generated via Biosynthetic Engineering of Streptomyces noursei ⬇️

scientific article published on July 15, 2011

Noursamycins, Chlorinated Cyclohexapeptides Identified from Molecular Networking of Streptomyces noursei NTR-SR4

scientific article published on 07 June 2019

Novel bioactive natural products from bacteria via bioprospecting, genome mining and metabolic engineering

scientific article published on 04 March 2019

Nystatin biosynthesis and transport: nysH and nysG genes encoding a putative ABC transporter system in Streptomyces noursei ATCC 11455 are required for efficient conversion of 10-deoxynystatin to nystatin.

scientific article published on November 2005

Piperazic acid containing peptides produced by an endophytic Streptomyces sp. isolated from the medicinal plant Atropa belladonna ⬇️

scientific article published on 13 July 2019

Polyene antibiotic biosynthesis gene clusters.

scientific article

Prauserella flavalba sp. nov., a novel species of the genus Prauserella, isolated from alkaline soil

scientific article

Probing the structure-function relationship of polyene macrolides: engineered biosynthesis of soluble nystatin analogues

scientific article

Production of a new thiopeptide antibiotic, TP-1161, by a marine Nocardiopsis species. ⬇️

scientific article

Rare actinomycete bacteria from the shallow water sediments of the Trondheim fjord, Norway: isolation, diversity and biological activity

scientific article

Rational design of macrolides by virtual screening of combinatorial libraries generated through in silico manipulation of polyketide synthases.

scientific article published in March 2006

Site-specific mutagenesis and domain substitutions in the loading module of the nystatin polyketide synthase, and their effects on nystatin biosynthesis in Streptomyces noursei. ⬇️

scientific article published on 19 February 2003

Streptomyces spp. From Ethiopia Producing Antimicrobial Compounds: Characterization via Bioassays, Genome Analyses, and Mass Spectrometry. ⬇️

scientific article

Structure-antifungal activity relationships of polyene antibiotics of the amphotericin B group

scientific article

Synthesis and study of the antifungal activity of new mono- and disubstituted derivatives of a genetically engineered polyene antibiotic 28,29-didehydronystatin A1 (S44HP).

scientific article published on 4 December 2009

The discovery of giant linear plasmids in strains of Streptomyces bambergiensis

scientific article published on 01 January 1990

The linear Streptomyces plasmid pBL1: analyses of transfer functions.

scientific article published in February 1994

Viennamycins: Lipopeptides Produced by a Streptomyces sp ⬇️

scientific article published on 31 July 2020

[Comparative analysis of in vitro antifungal activity and in vivo acute toxicity of the nystatin analogue S44HP produced via genetic engineering]

scientific article published on 01 January 2005

[Computer-aided design of polyketides with the required properties].

scientific article

[Effect of plasmid pIJ350 on genetic stability of antibiotic production by Streptomyces bambergiensis]

scientific article published on 01 March 1989

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