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List of works by Jarmo T Laitinen

2,3,7,8-Tetrachlorodibenzo-p-dioxin alters melatonin metabolism in fish hepatocytes

scientific article published on 01 June 2000

A Sensitive and Versatile Fluorescent Activity Assay for ABHD12.

scientific article published in January 2016

A Sensitive and Versatile Fluorescent Activity Assay for ABHD6.

scientific article published in January 2016

A rhodopsin-based model for melatonin recognition at its G protein-coupled receptor

scientific article published on 01 May 1996

A sensitive microassay reveals marked regional differences in the capacity of rat brain to generate carbon monoxide

scientific article published on 01 October 1995

Adenosine A1 receptor-dependent G-protein activity in the rat brain during prolonged wakefulness.

scientific article published in September 2004

Age and adjustment to night work.

scientific article

An optimized approach to study endocannabinoid signaling: evidence against constitutive activity of rat brain adenosine A1 and cannabinoid CB1 receptors ⬇️

scientific article (publication date: December 2003)

Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12)

scientific article

Brain regional cannabinoid CB(1) receptor signalling and alternative enzymatic pathways for 2-arachidonoylglycerol generation in brain sections of diacylglycerol lipase deficient mice

scientific article

Characterization of melatonin receptors in the rat area postrema: modulation of affinity with cations and guanine nucleotides

scientific article published in June 1990

Characterization of melatonin receptors in the rat suprachiasmatic nuclei: modulation of affinity with cations and guanine nucleotides

scientific article published in April 1990

Characterization of the sulfhydryl-sensitive site in the enzyme responsible for hydrolysis of 2-arachidonoyl-glycerol in rat cerebellar membranes

scientific article published in June 2005

Chiral 1,3,4-oxadiazol-2-ones as highly selective FAAH inhibitors

scientific article published on 22 October 2013

Circadian adjustment of men and women to night work

scientific article published in April 1996

Despite substantial degradation, 2-arachidonoylglycerol is a potent full efficacy agonist mediating CB(1) receptor-dependent G-protein activation in rat cerebellar membranes

scientific article

Different patterns of light exposure in relation to melatonin and cortisol rhythms and sleep of night workers

scientific article published in April 1994

Differential expression of melatonin receptors in spontaneously hypertensive rats

scientific article published on December 1, 1992

Differential regulation of the rat melatonin receptors: selective age-associated decline and lack of melatonin-induced changes

scientific article published in April 1992

Differential sensitivity to cations of the melatonin receptors in the rat area postrema and suprachiasmatic nuclei

scientific article published in October 1990

Discovery of 12-Thiazole Abietanes as Selective Inhibitors of the Human Metabolic Serine Hydrolase hABHD16A

scientific article published on 13 November 2018

Discovery of triterpenoids as reversible inhibitors of α/β-hydrolase domain containing 12 (ABHD12)

scientific article (publication date: 2014)

Diurnal rhythm of melatonin binding in the rat suprachiasmatic nucleus

scientific article published in March 1989

Diurnal rhythm of melatonin in bovine milk: pharmacokinetics of exogenous melatonin in lactating cows and goats

scientific article published on 01 January 1998

Dopamine stimulates K+ efflux in the chick retina via D1 receptors independently of adenylyl cyclase activation.

scientific article published in October 1993

Effects of continuous opioid receptor blockade on alcohol intake and up-regulation of opioid receptor subtype signalling in a genetic model of high alcohol drinking.

scientific article published in October 1999

Effects of melatonin implants in spring on testicular regression and moulting in adult male raccoon dogs (Nyctereutes procynoides)

scientific article published on 01 September 1995

Effects of melatonin implants on winter fur growth and testicular recrudescence in adult male raccoon dogs (Nyctereutes procyonoides)

scientific article published on 01 April 1996

Effects of mobile phone radiation on UV-induced skin tumourigenesis in ornithine decarboxylase transgenic and non-transgenic mice.

scientific article published on April 2003

Effects of topical anandamide-transport inhibitors, AM404 and olvanil, on intraocular pressure in normotensive rabbits.

scientific article published in April 2001

Exposure to a 50-hz magnetic field induces a circadian rhythm in 6-hydroxymelatonin sulfate excretion in mice.

scientific article

Extracellular UDP-glucose activates P2Y14 Receptor and Induces Signal Transducer and Activator of Transcription 3 (STAT3) Tyr705 phosphorylation and binding to hyaluronan synthase 2 (HAS2) promoter, stimulating hyaluronan synthesis of keratinocytes

scientific article published on 20 May 2014

Functional autoradiography shows unaltered cannabinoid CB1 receptor signalling in hippocampus and cortex of APP/PS1 transgenic mice

scientific article published in December 2012

Guanosine 5'-(gamma-[35S]thio)triphosphate autoradiography allows selective detection of histamine H3 receptor-dependent G protein activation in rat brain tissue sections.

scientific article published in August 1998

High-Resolution Confocal Fluorescence Imaging of Serine Hydrolase Activity in Cryosections - Application to Glioma Brain Unveils Activity Hotspots Originating from Tumor-Associated Neutrophils

scientific article published on 15 March 2020

Identification of WIN55212-3 as a competitive neutral antagonist of the human cannabinoid CB2 receptor

scientific article

Important amino acids for the function of the human MT1 melatonin receptor.

scientific article published in May 2003

In Vivo Characterization of the Ultrapotent Monoacylglycerol Lipase Inhibitor {4-[bis-(benzo[d][1,3]dioxol-5-yl)methyl]-piperidin-1-yl}(1H-1,2,4-triazol-1-yl)methanone (JJKK-048).

scientific article published on 22 July 2016

Increased tonic cannabinoid CB1R activity and brain region-specific desensitization of CB1R Gi/o signaling axis in mice with global genetic knockout of monoacylglycerol lipase

scientific article published on 9 June 2015

Intracerebroventricular antisense knockdown of G alpha i2 results in ciliary stasis and ventricular dilatation in the rat.

scientific article

Inverse agonist exposure enhances ligand binding and G protein activation of the human MT1 melatonin receptor, but leads to receptor down-regulation.

scientific article published on October 2007

Level and distribution of progesterone in bovine milk: effects of mastitis and milk composition

scientific article published on 01 November 1986

Lipid phosphate phosphatase inhibitors locally amplify lysophosphatidic acid LPA1 receptor signalling in rat brain cryosections without affecting global LPA degradation

scientific article

Localization and variable expression of G alpha(i2) in human endometrium and Fallopian tubes.

scientific article published on 8 March 2007

Long-term induction of haem oxygenase-1 (HSP-32) in astrocytes and microglia following transient focal brain ischaemia in the rat.

scientific article

Mechanism by which 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) reduces circulating melatonin levels in the rat.

scientific article published in February 1996

Melatonin receptor genes.

scientific article published on February 1998

Milk progesterone in Finnish dairy cows: a field study on the control of artificial insemination and early pregnancy

Monoglyceride lipase as an enzyme hydrolyzing 2-arachidonoylglycerol.

scientific article published on August 2007

Monoglyceride lipase-like enzymatic activity is responsible for hydrolysis of 2-arachidonoylglycerol in rat cerebellar membranes.

scientific article published on April 2004

Mutagenesis of human Mel1a melatonin receptor expressed in yeast reveals domains important for receptor function

scientific article published on 01 August 1998

Neuroanatomical mapping of juvenile rat brain regions with prominent basal signal in [(35)S]GTPgammaS autoradiography.

scientific article

Oestrus and pregnancy diagnosis by milk progesterone assay in the mare

scientific article published on 01 September 1981

On the respective roles of nitric oxide and carbon monoxide in long-term potentiation in the hippocampus

scientific article published on 01 January 1999

On the respective roles of nitric oxide and carbon monoxide in long-term potentiation in the hippocampus.

scientific article

Overexpression of heme oxygenase in neuronal cells, the possible interaction with Tau

scientific article published in Journal of Biological Chemistry

Pineal muscarinic phosphoinositide response: pertussis toxin resistant signaling with very low receptor number

scientific article published in October 1989

Pineal muscarinic phosphoinositide responses: age-associated sensitization, agonist-induced desensitization and increase in melatonin release from cultured pineal glands

scientific article published in May 1992

Potent and selective N-(4-sulfamoylphenyl)thiourea-based GPR55 agonists

scientific article published on 2 November 2015

Protective properties of tin- and manganese-centered porphyrins against hydrogen peroxide-mediated injury in rat astroglial cells.

scientific article published on December 1998

Quantification of lysophosphatidic acids in rat brain tissue by liquid chromatography-electrospray tandem mass spectrometry

scientific article published on 20 March 2010

Relation of age to circadian adjustment to night work

scientific article published in January 1992

Renal melatonin excretion in sheep is enhanced by water diuresis

scientific article published on 01 September 1993

Revisiting 1,3,4-Oxadiazol-2-ones: Utilization in the Development of ABHD6 Inhibitors

scientific article published on 28 August 2015

Selective detection of adenosine A1 receptor-dependent G-protein activity in basal and stimulated conditions of rat brain [35S]guanosine 5'-(gamma-thio)triphosphate autoradiography

scientific article published in January 1999

Synthesis and CB1 receptor activities of dimethylheptyl derivatives of 2-arachidonoyl glycerol (2-AG) and 2-arachidonyl glyceryl ether (2-AGE).

scientific article published on 5 January 2006

Synthesis and SAR studies of 2-oxoquinoline derivatives as CB2 receptor inverse agonists.

scientific article

Synthesis and in vitro pharmacology of a series of new chiral histamine H3-receptor ligands: 2-(R and S)-Amino-3-(1H-imidazol-4(5)-yl)propyl ether derivatives.

scientific article published in April 1999

Synthesis and preclinical evaluation of [11C]MA-PB-1 for in vivo imaging of brain monoacylglycerol lipase (MAGL).

scientific article published on 25 April 2017

Synthesis, cannabinoid receptor activity, and enzymatic stability of reversed amide derivatives of arachidonoyl ethanolamide.

scientific article published on 27 April 2006

TCDD reduces serum melatonin levels in Long-Evans rats

scientific article published on 01 September 1989

The 'allosteric modulator' SCH-202676 disrupts G protein-coupled receptor function via sulphydryl-sensitive mechanisms.

scientific article published on February 2006

The basic secretagogue compound 48/80 activates G proteins indirectly via stimulation of phospholipase D-lysophosphatidic acid receptor axis and 5-HT1A receptors in rat brain sections.

scientific article published on March 2006

The chick retinal melatonin receptor revisited: localization and modulation of agonist binding with guanine nucleotides

scientific article published in October 1990

The effect of four-day round trip flights over 10 time zones on the circadian variation of salivary melatonin and Cortisol in airline flight attendants

scientific article published on 01 September 1994

The effect of photoperiod on diel rhythms in serum melatonin, cortisol, glucose, and electrolytes in the common dentex, Dentex dentex

scientific article published on 01 February 1999

The functional role of cysteines adjacent to the NRY motif of the human MT1 melatonin receptor.

scientific article published in August 2005

The prediction of the adaptation of circadian rhythms to rapid time zone changes

scientific article published on 01 January 1993

The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2-arachidonoylglycerol signalling through cannabinoid receptors

scientific article

Therapeutic potential of endocannabinoid-hydrolysing enzyme inhibitors.

scientific article published on November 2007

Virtual screening of novel CB2 ligands using a comparative model of the human cannabinoid CB2 receptor.

scientific article published in November 2005

Visualization of 2-arachidonoylglycerol accumulation and cannabinoid CB1 receptor activity in rat brain cryosections by functional autoradiography

scientific article published on 24 January 2007

[(35)S]GTPgammaS autoradiography reveals a wide distribution of G(i/o)-linked ADP receptors in the nervous system: close similarities with the platelet P2Y(ADP) receptor.

scientific article published on April 2001

[Gamma-35S]GTP autoradiography allows region-specific detection of muscarinic receptor-dependent G-protein activation in the chick optic tectum

scientific article published in September 1997

[Physiology of the biological clock and the relation of circadian rhythm disorders to illnesses]

scientific article published on 01 January 1999

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